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Items: 47

1.

Interactions of pesticides with membrane drug transporters: implications for toxicokinetics and toxicity.

Chedik L, Bruyere A, Bacle A, Potin S, Le Vée M, Fardel O.

Expert Opin Drug Metab Toxicol. 2018 Jul;14(7):739-752. doi: 10.1080/17425255.2018.1487398. Epub 2018 Jun 20. Review.

PMID:
29886753
2.

Carrier-mediated uptake of clonidine in cultured human lung cells.

Le Vée M, Jouan E, Fardel O.

Naunyn Schmiedebergs Arch Pharmacol. 2018 Apr;391(4):361-369. doi: 10.1007/s00210-018-1467-7. Epub 2018 Jan 19.

PMID:
29352450
3.

The JAK1/2 Inhibitor Ruxolitinib Reverses Interleukin-6-Mediated Suppression of Drug-Detoxifying Proteins in Cultured Human Hepatocytes.

Febvre-James M, Bruyère A, Le Vée M, Fardel O.

Drug Metab Dispos. 2018 Feb;46(2):131-140. doi: 10.1124/dmd.117.078048. Epub 2017 Nov 21.

PMID:
29162613
4.

Inhibition of organic anion transporter (OAT) activity by cigarette smoke condensate.

Sayyed K, Le Vee M, Abdel-Razzak Z, Fardel O.

Toxicol In Vitro. 2017 Oct;44:27-35. doi: 10.1016/j.tiv.2017.06.014. Epub 2017 Jun 17.

5.

Protein Kinases C-Mediated Regulations of Drug Transporter Activity, Localization and Expression.

Mayati A, Moreau A, Le Vée M, Stieger B, Denizot C, Parmentier Y, Fardel O.

Int J Mol Sci. 2017 Apr 4;18(4). pii: E764. doi: 10.3390/ijms18040764. Review.

6.

Effect of Gevokizumab on Interleukin-1β-Mediated Cytochrome P450 3A4 and Drug Transporter Repression in Cultured Human Hepatocytes.

Moreau A, Le Vée M, Jouan E, Denizot C, Parmentier Y, Fardel O.

Eur J Drug Metab Pharmacokinet. 2017 Oct;42(5):871-878. doi: 10.1007/s13318-017-0406-1.

PMID:
28260174
7.

Inhibition of Human Drug Transporter Activities by the Pyrethroid Pesticides Allethrin and Tetramethrin.

Chedik L, Bruyere A, Le Vee M, Stieger B, Denizot C, Parmentier Y, Potin S, Fardel O.

PLoS One. 2017 Jan 18;12(1):e0169480. doi: 10.1371/journal.pone.0169480. eCollection 2017.

8.

Drug Transporter Expression and Activity in Human Hepatoma HuH-7 Cells.

Jouan E, Le Vée M, Denizot C, Parmentier Y, Fardel O.

Pharmaceutics. 2016 Dec 28;9(1). pii: E3. doi: 10.3390/pharmaceutics9010003.

9.

Inhibition of SLC drug transporter activities by environmental bisphenols.

Bruyere A, Hubert C, Le Vee M, Chedik L, Sayyed K, Stieger B, Denizot C, Parmentier Y, Fardel O.

Toxicol In Vitro. 2017 Apr;40:34-44. doi: 10.1016/j.tiv.2016.12.009. Epub 2016 Dec 15.

PMID:
27989701
10.

Evaluation of P-Glycoprotein Inhibitory Potential Using a Rhodamine 123 Accumulation Assay.

Jouan E, Le Vée M, Mayati A, Denizot C, Parmentier Y, Fardel O.

Pharmaceutics. 2016 Apr 12;8(2). pii: E12. doi: 10.3390/pharmaceutics8020012.

11.

Aryl hydrocarbon receptor-dependent up-regulation of the heterodimeric amino acid transporter LAT1 (SLC7A5)/CD98hc (SLC3A2) by diesel exhaust particle extract in human bronchial epithelial cells.

Le Vee M, Jouan E, Lecureur V, Fardel O.

Toxicol Appl Pharmacol. 2016 Jan 1;290:74-85. doi: 10.1016/j.taap.2015.11.014. Epub 2015 Nov 24.

12.

Protein kinase C-dependent regulation of human hepatic drug transporter expression.

Mayati A, Le Vee M, Moreau A, Jouan E, Bucher S, Stieger B, Denizot C, Parmentier Y, Fardel O.

Biochem Pharmacol. 2015 Dec 15;98(4):703-17. doi: 10.1016/j.bcp.2015.10.007. Epub 2015 Oct 14.

13.

Analysis of Sinusoidal Drug Uptake Transporter Activities in Primary Human Hepatocytes.

Le Vée M, Jouan E, Denizot C, Parmentier Y, Fardel O.

Methods Mol Biol. 2015;1250:287-302. doi: 10.1007/978-1-4939-2074-7_21.

PMID:
26272151
14.

Nature and uses of fluorescent dyes for drug transporter studies.

Fardel O, Le Vee M, Jouan E, Denizot C, Parmentier Y.

Expert Opin Drug Metab Toxicol. 2015;11(8):1233-51. doi: 10.1517/17425255.2015.1053462. Epub 2015 Jun 7. Review.

PMID:
26050735
15.

Polarized location of SLC and ABC drug transporters in monolayer-cultured human hepatocytes.

Le Vee M, Jouan E, Noel G, Stieger B, Fardel O.

Toxicol In Vitro. 2015 Aug;29(5):938-46. doi: 10.1016/j.tiv.2015.03.019. Epub 2015 Apr 7.

16.

Regulation of human hepatic drug transporter activity and expression by diesel exhaust particle extract.

Le Vee M, Jouan E, Stieger B, Lecureur V, Fardel O.

PLoS One. 2015 Mar 24;10(3):e0121232. doi: 10.1371/journal.pone.0121232. eCollection 2015.

17.

Regulation of hepatic drug transporter activity and expression by organochlorine pesticides.

Bucher S, Le Vee M, Jouan E, Fardel O.

J Biochem Mol Toxicol. 2014 Mar;28(3):119-28. doi: 10.1002/jbt.21543. Epub 2013 Nov 27.

PMID:
24464585
18.

Differentiation of human placental BeWo cells by the environmental contaminant benzo(a)pyrene.

Le Vee M, Kolasa E, Jouan E, Collet N, Fardel O.

Chem Biol Interact. 2014 Mar 5;210:1-11. doi: 10.1016/j.cbi.2013.12.004. Epub 2013 Dec 17.

PMID:
24361490
19.

Polarized expression of drug transporters in differentiated human hepatoma HepaRG cells.

Le Vee M, Noel G, Jouan E, Stieger B, Fardel O.

Toxicol In Vitro. 2013 Sep;27(6):1979-86. doi: 10.1016/j.tiv.2013.07.003. Epub 2013 Jul 12.

20.

Functional expression and regulation of drug transporters in monolayer- and sandwich-cultured mouse hepatocytes.

Noel G, Le Vee M, Moreau A, Stieger B, Parmentier Y, Fardel O.

Eur J Pharm Sci. 2013 Apr 11;49(1):39-50. doi: 10.1016/j.ejps.2013.01.013. Epub 2013 Feb 6.

21.

Differential regulation of drug transporter expression by all-trans retinoic acid in hepatoma HepaRG cells and human hepatocytes.

Le Vee M, Jouan E, Stieger B, Fardel O.

Eur J Pharm Sci. 2013 Mar 12;48(4-5):767-74. doi: 10.1016/j.ejps.2013.01.005. Epub 2013 Jan 23.

22.

The mitochondrial fluorescent dye rhodamine 123 is a high-affinity substrate for organic cation transporters (OCTs) 1 and 2.

Jouan E, Le Vee M, Denizot C, Da Violante G, Fardel O.

Fundam Clin Pharmacol. 2014 Feb;28(1):65-77. doi: 10.1111/j.1472-8206.2012.01071.x. Epub 2012 Aug 23.

PMID:
22913740
23.

Environmental chemicals as substrates, inhibitors or inducers of drug transporters: implication for toxicokinetics, toxicity and pharmacokinetics.

Fardel O, Kolasa E, Le Vee M.

Expert Opin Drug Metab Toxicol. 2012 Jan;8(1):29-46. doi: 10.1517/17425255.2012.637918. Epub 2011 Dec 19. Review.

PMID:
22176607
24.

MAPK- and PKC/CREB-dependent induction of interleukin-11 by the environmental contaminant formaldehyde in human bronchial epithelial cells.

Lecureur V, Arzel M, Ameziane S, Houlbert N, Le Vee M, Jouneau S, Fardel O.

Toxicology. 2012 Feb 6;292(1):13-22. doi: 10.1016/j.tox.2011.11.011. Epub 2011 Nov 28.

PMID:
22138297
25.

Regulation of drug transporter expression by oncostatin M in human hepatocytes.

Le Vee M, Jouan E, Stieger B, Lecureur V, Fardel O.

Biochem Pharmacol. 2011 Aug 1;82(3):304-11. doi: 10.1016/j.bcp.2011.04.017. Epub 2011 May 6.

26.

RNAi-based screening identifies kinases interfering with dioxin-mediated up-regulation of CYP1A1 activity.

Gilot D, Le Meur N, Giudicelli F, Le Vée M, Lagadic-Gossmann D, Théret N, Fardel O.

PLoS One. 2011 Mar 29;6(3):e18261. doi: 10.1371/journal.pone.0018261.

27.

Drug transporter expression in human macrophages.

Moreau A, Le Vee M, Jouan E, Parmentier Y, Fardel O.

Fundam Clin Pharmacol. 2011 Dec;25(6):743-52. doi: 10.1111/j.1472-8206.2010.00913.x. Epub 2011 Jan 7.

PMID:
21210849
28.

Involvement of aryl hydrocarbon receptor in basal and 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced expression of target genes in primary human hepatocytes.

Le Vee M, Jouan E, Fardel O.

Toxicol In Vitro. 2010 Sep;24(6):1775-81. doi: 10.1016/j.tiv.2010.07.001. Epub 2010 Jul 7.

PMID:
20619336
29.

Regulation of drug transporter mRNA expression by interferon-γ in primary human hepatocytes.

Le Vee M, Jouan E, Moreau A, Fardel O.

Fundam Clin Pharmacol. 2011 Feb;25(1):99-103. doi: 10.1111/j.1472-8206.2010.00822.x.

PMID:
20199580
30.

Regulation of human hepatic drug transporter expression by pro-inflammatory cytokines.

Fardel O, Le Vée M.

Expert Opin Drug Metab Toxicol. 2009 Dec;5(12):1469-81. doi: 10.1517/17425250903304056. Review.

PMID:
19785515
31.

Differential regulation of drug transporter expression by hepatocyte growth factor in primary human hepatocytes.

Le Vee M, Lecureur V, Moreau A, Stieger B, Fardel O.

Drug Metab Dispos. 2009 Nov;37(11):2228-35. doi: 10.1124/dmd.109.028035. Epub 2009 Aug 6.

32.

TNFalpha- and NF-kappaB-dependent induction of the chemokine CCL1 in human macrophages exposed to the atherogenic lipoprotein(a).

N'Diaye M, Le Ferrec E, Kronenberg F, Dieplinger H, Le Vee M, Fardel O.

Life Sci. 2009 Mar 27;84(13-14):451-7. doi: 10.1016/j.lfs.2009.01.012. Epub 2009 Feb 2.

PMID:
19302817
33.

Regulation of drug transporter expression in human hepatocytes exposed to the proinflammatory cytokines tumor necrosis factor-alpha or interleukin-6.

Le Vee M, Lecureur V, Stieger B, Fardel O.

Drug Metab Dispos. 2009 Mar;37(3):685-93. doi: 10.1124/dmd.108.023630. Epub 2008 Dec 15.

34.

Analysis of drug transporter expression in human intestinal Caco-2 cells by real-time PCR.

Maubon N, Le Vee M, Fossati L, Audry M, Le Ferrec E, Bolze S, Fardel O.

Fundam Clin Pharmacol. 2007 Dec;21(6):659-63.

PMID:
18034668
35.

Down-regulation of organic anion transporter expression in human hepatocytes exposed to the proinflammatory cytokine interleukin 1beta.

Le Vee M, Gripon P, Stieger B, Fardel O.

Drug Metab Dispos. 2008 Feb;36(2):217-22. Epub 2007 Nov 8.

36.

AhR- and c-maf-dependent induction of beta7-integrin expression in human macrophages in response to environmental polycyclic aromatic hydrocarbons.

Monteiro P, Gilot D, Le Ferrec E, Lecureur V, N'diaye M, Le Vee M, Podechard N, Pouponnot C, Fardel O.

Biochem Biophys Res Commun. 2007 Jun 29;358(2):442-8. Epub 2007 Apr 26.

PMID:
17490615
37.

Differential regulation of sinusoidal and canalicular hepatic drug transporter expression by xenobiotics activating drug-sensing receptors in primary human hepatocytes.

Jigorel E, Le Vee M, Boursier-Neyret C, Parmentier Y, Fardel O.

Drug Metab Dispos. 2006 Oct;34(10):1756-63. Epub 2006 Jul 12.

38.

Functional expression of sinusoidal and canalicular hepatic drug transporters in the differentiated human hepatoma HepaRG cell line.

Le Vee M, Jigorel E, Glaise D, Gripon P, Guguen-Guillouzo C, Fardel O.

Eur J Pharm Sci. 2006 May;28(1-2):109-17. Epub 2006 Feb 20.

PMID:
16488578
39.

Potent inhibition of carcinogen-bioactivating cytochrome P450 1B1 by the p53 inhibitor pifithrin alpha.

Sparfel L, Van Grevenynghe J, Le Vee M, Aninat C, Fardel O.

Carcinogenesis. 2006 Mar;27(3):656-63. Epub 2005 Oct 29.

PMID:
16258175
40.

Functional expression of sinusoidal drug transporters in primary human and rat hepatocytes.

Jigorel E, Le Vee M, Boursier-Neyret C, Bertrand M, Fardel O.

Drug Metab Dispos. 2005 Oct;33(10):1418-22. Epub 2005 Jul 13.

41.

Physiological, pharmacological and clinical features of the multidrug resistance protein 2.

Fardel O, Jigorel E, Le Vee M, Payen L.

Biomed Pharmacother. 2005 Apr;59(3):104-14. Review.

PMID:
15795103
42.

Inhibition of carcinogen-bioactivating cytochrome P450 1 isoforms by amiloride derivatives.

Sparfel L, Huc L, Le Vee M, Desille M, Lagadic-Gossmann D, Fardel O.

Biochem Pharmacol. 2004 May 1;67(9):1711-9.

PMID:
15081870
43.

Cytochrome P450-dependent toxicity of environmental polycyclic aromatic hydrocarbons towards human macrophages.

van Grevenynghe J, Sparfel L, Le Vee M, Gilot D, Drenou B, Fauchet R, Fardel O.

Biochem Biophys Res Commun. 2004 May 7;317(3):708-16.

PMID:
15081398
44.

Specificity of three ELISA-gE kits for screening pig meat for antibodies to Aujeszky's disease.

De Lange K, Haddad N, Le Potier MF, Agier C, Le Vée M, Amar P, Toma B.

Vet Rec. 2003 Nov 15;153(20):621-4.

PMID:
14653341
45.

Polycyclic aromatic hydrocarbons inhibit differentiation of human monocytes into macrophages.

van Grevenynghe J, Rion S, Le Ferrec E, Le Vee M, Amiot L, Fauchet R, Fardel O.

J Immunol. 2003 Mar 1;170(5):2374-81.

46.
47.

Transcriptional induction of CYP1A1 by oltipraz in human Caco-2 cells is aryl hydrocarbon receptor- and calcium-dependent.

Le Ferrec E, Lagadic-Gossmann D, Rauch C, Bardiau C, Maheo K, Massiere F, Le Vee M, Guillouzo A, Morel F.

J Biol Chem. 2002 Jul 5;277(27):24780-7. Epub 2002 Apr 16.

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