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Items: 1 to 50 of 186

1.

Western oropharyngeal and gut microbial profiles are associated with allergic conditions in Chinese immigrant children.

Guo J, Lv Q, Ariff A, Zhang X, Peacock CS, Song Y, Wen X, Saiganesh A, Melton PE, Dykes GA, Moses EK, LE Souëf PN, Lu F, Zhang G.

World Allergy Organ J. 2019 Aug 9;12(8):100051. doi: 10.1016/j.waojou.2019.100051. eCollection 2019 Aug.

2.

Suboptimal asthma care: Lessons from Australia and a way forward.

Schultz A, le Souef P, Barwick M.

Respirology. 2019 Aug 3. doi: 10.1111/resp.13661. [Epub ahead of print] No abstract available.

3.

Progressive increase of FcεRI expression across several PBMC subsets is associated with atopy and atopic asthma within school-aged children.

Leffler J, Read JF, Jones AC, Mok D, Hollams EM, Laing IA, Le Souef PN, Sly PD, Kusel MMH, de Klerk NH, Bosco A, Holt PG, Strickland DH.

Pediatr Allergy Immunol. 2019 Sep;30(6):646-653. doi: 10.1111/pai.13063. Epub 2019 May 22.

PMID:
30985951
4.

Upper Airway Cell Transcriptomics Identify a Major New Immunological Phenotype with Strong Clinical Correlates in Young Children with Acute Wheezing.

Khoo SK, Read J, Franks K, Zhang G, Bizzintino J, Coleman L, McCrae C, Öberg L, Troy NM, Prastanti F, Everard J, Oo S, Borland ML, Maciewicz RA, Le Souëf PN, Laing IA, Bosco A.

J Immunol. 2019 Mar 15;202(6):1845-1858. doi: 10.4049/jimmunol.1800178. Epub 2019 Feb 11.

PMID:
30745463
5.

Glutathione S-Transferase Genotype Protects against In Utero Tobacco-linked Lung Function Deficits.

Owens L, Laing IA, Murdzoska J, Zhang G, Turner SW, Le Souëf PN.

Am J Respir Crit Care Med. 2019 Aug 15;200(4):462-470. doi: 10.1164/rccm.201807-1332OC.

PMID:
30726102
6.

Pediatric asthma: An unmet need for more effective, focused treatments.

Papadopoulos NG, Čustović A, Cabana MD, Dell SD, Deschildre A, Hedlin G, Hossny E, Le Souëf P, Matricardi PM, Nieto A, Phipatanakul W, Pitrez PM, Pohunek P, Gavornikova M, Jaumont X, Price DB.

Pediatr Allergy Immunol. 2019 Feb;30(1):7-16. doi: 10.1111/pai.12990. Epub 2018 Nov 15. Review.

7.

Prevalence of allergic sensitization, hay fever, eczema, and asthma in a longitudinal birth cohort.

Owens L, Laing IA, Zhang G, Turner S, Le Souëf PN.

J Asthma Allergy. 2018 Aug 13;11:173-180. doi: 10.2147/JAA.S170285. eCollection 2018.

8.

Basophil counts in PBMC populations during childhood acute wheeze/asthma are associated with future exacerbations.

Leffler J, Jones AC, Hollams EM, Prastanti F, Le Souëf PN, Holt PG, Bosco A, Laing IA, Strickland DH.

J Allergy Clin Immunol. 2018 Nov;142(5):1639-1641.e5. doi: 10.1016/j.jaci.2018.07.003. Epub 2018 Jul 21. No abstract available.

PMID:
30036597
9.

Rhinovirus is the most common virus and rhinovirus-C is the most common species in paediatric intensive care respiratory admissions.

Cox DW, Khoo SK, Zhang G, Lindsay K, Keil AD, Knight G, Gern JE, Laing IA, Bizzintino J, Le Souëf PN.

Eur Respir J. 2018 Aug 9;52(2). pii: 1800207. doi: 10.1183/13993003.00207-2018. Print 2018 Aug. No abstract available.

10.

Airway Interleukin-33 and type 2 cytokines in adult patients with acute asthma.

Poulsen NN, Bjerregaard A, Khoo SK, Laing IA, Le Souëf P, Backer V, Rapley L, Cohen SE, Barrett L, Thompson P, Baltic S, Porsbjerg C.

Respir Med. 2018 Jul;140:50-56. doi: 10.1016/j.rmed.2018.05.016. Epub 2018 May 19.

PMID:
29957280
11.

A marked shift in innate and adaptive immune response in chinese immigrants living in a western environment.

Saiganesh A, Hales BJ, Li Y, Holt PG, Le Souëf PN, Zhang G.

Allergy. 2018 Oct;73(10):2092-2094. doi: 10.1111/all.13531. Epub 2018 Jul 11. No abstract available.

PMID:
29935021
12.

Airway function in infancy is linked to airflow measurements and respiratory symptoms from childhood into adulthood.

Owens L, Laing IA, Zhang G, Turner S, Le Souëf PN.

Pediatr Pulmonol. 2018 Aug;53(8):1082-1088. doi: 10.1002/ppul.24062. Epub 2018 May 27.

PMID:
29806178
13.

Lung function trajectories from pre-school age to adulthood and their associations with early life factors: a retrospective analysis of three population-based birth cohort studies.

Belgrave DCM, Granell R, Turner SW, Curtin JA, Buchan IE, Le Souëf PN, Simpson A, Henderson AJ, Custovic A.

Lancet Respir Med. 2018 Jul;6(7):526-534. doi: 10.1016/S2213-2600(18)30099-7. Epub 2018 Apr 5.

14.

Viral infections in wheezing disorders.

Le Souëf P.

Eur Respir Rev. 2018 Apr 5;27(147). pii: 170133. doi: 10.1183/16000617.0133-2017. Print 2018 Mar 31. Review.

15.

Prospective Assessment of Rhinovirus Symptoms and Species Recurrence in Children With and Without an Acute Wheezing Exacerbation.

Lethbridge R, Prastanti F, Robertson C, Oo S, Khoo SK, Le Souëf PN, Laing IA.

Viral Immunol. 2018 May;31(4):299-305. doi: 10.1089/vim.2017.0152. Epub 2018 Feb 15.

PMID:
29446705
16.

Association between pro-inflammatory alleles and allergic phenotypes in Xhosa adolescents.

Laurence C, van der Merwe L, Zhang G, Le Souëf P, Levin M.

Pediatr Allergy Immunol. 2018 May;29(3):311-317. doi: 10.1111/pai.12859. Epub 2018 Feb 6.

PMID:
29314322
17.

The Western environment reduces innate immune cytokine production in Chinese immigrants.

Saiganesh A, Hales BJ, Chen S, Filipovska-Naumovska E, Pereira G, Garand M, Kollmann TR, Currie AJ, Le Souëf PN, Zhang G.

J Allergy Clin Immunol. 2018 Apr;141(4):1504-1507.e3. doi: 10.1016/j.jaci.2017.11.031. Epub 2017 Dec 21. No abstract available.

PMID:
29274412
18.

Genetic Variants in the IL-4/IL-13 Pathway Influence Measles Vaccine Responses and Vaccine Failure in Children from Mozambique.

Clifford HD, Hayden CM, Khoo SK, Naniche D, Mandomando IM, Zhang G, Richmond P, Le Souëf PN.

Viral Immunol. 2017 Sep;30(7):472-478. doi: 10.1089/vim.2017.0014. Epub 2017 Jun 8.

PMID:
28594599
19.

High fractional exhaled nitric oxide and sputum eosinophils are associated with an increased risk of future virus-induced exacerbations: A prospective cohort study.

Bjerregaard A, Laing IA, Backer V, Sverrild A, Khoo SK, Chidlow G, Sikazwe C, Smith DW, Le Souëf P, Porsbjerg C.

Clin Exp Allergy. 2017 Aug;47(8):1007-1013. doi: 10.1111/cea.12935. Epub 2017 May 9.

PMID:
28390083
20.

Characteristics associated with clinical severity and inflammatory phenotype of naturally occurring virus-induced exacerbations of asthma in adults.

Bjerregaard A, Laing IA, Poulsen N, Backer V, Sverrild A, Fally M, Khoo SK, Barrett L, Baltic S, Thompson PJ, Chidlow G, Sikazwe C, Smith DW, Bochkov YA, Le Souëf P, Porsbjerg C.

Respir Med. 2017 Feb;123:34-41. doi: 10.1016/j.rmed.2016.12.010. Epub 2016 Dec 18.

21.

Knowledge, attitudes and practices regarding tuberculosis care among health workers in Southern Mozambique.

Noé A, Ribeiro RM, Anselmo R, Maixenchs M, Sitole L, Munguambe K, Blanco S, le Souef P, García-Basteiro AL.

BMC Pulm Med. 2017 Jan 5;17(1):2. doi: 10.1186/s12890-016-0344-8.

22.

Rhinovirus C is associated with wheezing and rhinovirus A is associated with pneumonia in hospitalized children in Morocco.

Annamalay AA, Jroundi I, Bizzintino J, Khoo SK, Zhang G, Lehmann D, Laing IA, Gern J, Goldblatt J, Mahraoui C, Benmessaoud R, Moraleda C, Bassat Q, Le Souëf P.

J Med Virol. 2017 Apr;89(4):582-588. doi: 10.1002/jmv.24684. Epub 2016 Sep 30.

PMID:
27677921
23.

Clinical characteristics of eosinophilic asthma exacerbations.

Bjerregaard A, Laing IA, Backer V, Fally M, Khoo SK, Chidlow G, Sikazwe C, Smith DW, Le Souëf P, Porsbjerg C.

Respirology. 2017 Feb;22(2):295-300. doi: 10.1111/resp.12905. Epub 2016 Sep 21.

PMID:
27649851
24.

Infant lung function predicts asthma persistence and remission in young adults.

Owens L, Laing IA, Zhang G, Le Souëf PN.

Respirology. 2017 Feb;22(2):289-294. doi: 10.1111/resp.12901. Epub 2016 Sep 16.

25.

Immunodominant T-Cell Epitopes in the VP1 Capsid Protein of Rhinovirus Species A and C.

Gaido CM, Stone S, Chopra A, Thomas WR, Le Souëf PN, Hales BJ.

J Virol. 2016 Nov 14;90(23):10459-10471. doi: 10.1128/JVI.01701-16. Print 2016 Dec 1.

26.

Gene-based analysis of regulatory variants identifies 4 putative novel asthma risk genes related to nucleotide synthesis and signaling.

Ferreira MA, Jansen R, Willemsen G, Penninx B, Bain LM, Vicente CT, Revez JA, Matheson MC, Hui J, Tung JY, Baltic S, Le Souëf P, Montgomery GW, Martin NG, Robertson CF, James A, Thompson PJ, Boomsma DI, Hopper JL, Hinds DA, Werder RB, Phipps S; Australian Asthma Genetics Consortium Collaborators.

J Allergy Clin Immunol. 2017 Apr;139(4):1148-1157. doi: 10.1016/j.jaci.2016.07.017. Epub 2016 Aug 20.

27.

The use of inhaled corticosteroids in pediatric asthma: update.

Hossny E, Rosario N, Lee BW, Singh M, El-Ghoneimy D, Soh JY, Le Souef P.

World Allergy Organ J. 2016 Aug 12;9:26. doi: 10.1186/s40413-016-0117-0. eCollection 2016. Review.

28.

Rhinovirus species and clinical features in children hospitalised with pneumonia from Mozambique.

Annamalay AA, Lanaspa M, Khoo SK, Madrid L, Acácio S, Zhang G, Laing IA, Gern J, Goldblatt J, Bizzintino J, Lehmann D, Le Souëf PN, Bassat Q.

Trop Med Int Health. 2016 Sep;21(9):1171-80. doi: 10.1111/tmi.12743. Epub 2016 Jul 26.

29.

Respiratory viruses in young South African children with acute lower respiratory infections and interactions with HIV.

Annamalay AA, Abbott S, Sikazwe C, Khoo SK, Bizzintino J, Zhang G, Laing I, Chidlow GR, Smith DW, Gern J, Goldblatt J, Lehmann D, Green RJ, Le Souëf PN.

J Clin Virol. 2016 Aug;81:58-63. doi: 10.1016/j.jcv.2016.06.002. Epub 2016 Jun 4.

PMID:
27317881
30.

Pressurised metered dose inhaler-spacer technique in young children improves with video instruction.

Shaw N, Le Souëf P, Turkovic L, McCahon L, Kicic A, Sly PD, Devadason S, Schultz A.

Eur J Pediatr. 2016 Jul;175(7):1007-12. doi: 10.1007/s00431-016-2738-2. Epub 2016 Jun 1.

PMID:
27251668
31.

Early sensitization is associated with reduced lung function from birth into adulthood.

Owens L, Laing I, Zhang G, Le Souef P.

J Allergy Clin Immunol. 2016 May;137(5):1605-1607.e2. doi: 10.1016/j.jaci.2015.10.030. Epub 2015 Dec 10. No abstract available.

PMID:
26686471
32.

Asthma education material for children and their families; a global survey of current resources.

Everard ML, Wahn U, Dorsano S, Hossny E, Le Souef P.

World Allergy Organ J. 2015 Dec 14;8:35. doi: 10.1186/s40413-015-0084-x. eCollection 2015.

33.

Western environment/lifestyle is associated with increased genome methylation and decreased gene expression in Chinese immigrants living in Australia.

Zhang G, Wang K, Schultz E, Khoo SK, Zhang X, Annamalay A, Laing IA, Hales BJ, Goldblatt J, Le Souëf PN.

Environ Mol Mutagen. 2016 Jan;57(1):65-73. doi: 10.1002/em.21989. Epub 2015 Dec 16.

PMID:
26671525
34.

Longitudinal assessment of airway responsiveness from 1 month to 18 years in the PIAF birth cohort.

Cox DW, Mullane D, Zhang GC, Turner SW, Hayden CM, Goldblatt J, Landau LI, Le Souëf PN.

Eur Respir J. 2015 Dec;46(6):1654-61. doi: 10.1183/13993003.00397-2015. Epub 2015 Oct 22.

35.

The wheezing child: an algorithm.

Oo S, Le Souëf P.

Aust Fam Physician. 2015 Jun;44(6):360-4.

36.

Rhinovirus-C detection in children presenting with acute respiratory infection to hospital in Brazil.

Fawkner-Corbett DW, Khoo SK, Duarte CM, Bezerra PG, Bochkov YA, Gern JE, Le Souef PN, McNamara PS.

J Med Virol. 2016 Jan;88(1):58-63. doi: 10.1002/jmv.24300.

37.

Lower anti-echovirus antibody responses in children presenting to hospital with asthma exacerbations.

Iwasaki J, Chai LY, Khoo SK, Bizzintino J, Laing IA, Le Souëf PN, Thomas WR, Hales BJ.

Clin Exp Allergy. 2015 Oct;45(10):1523-30. doi: 10.1111/cea.12501.

PMID:
25640320
38.

A longitudinal study of lung function from 1 month to 18 years of age.

Turner S, Fielding S, Mullane D, Cox DW, Goldblatt J, Landau L, le Souef P.

Thorax. 2014 Nov;69(11):1015-20. doi: 10.1136/thoraxjnl-2013-204931. Epub 2014 Jun 2.

PMID:
24891326
39.

Comparison of rhinovirus antibody titers in children with asthma exacerbations and species-specific rhinovirus infection.

Iwasaki J, Smith WA, Khoo SK, Bizzintino J, Zhang G, Cox DW, Laing IA, Le Souëf PN, Thomas WR, Hales BJ.

J Allergy Clin Immunol. 2014 Jul;134(1):25-32. doi: 10.1016/j.jaci.2014.03.014. Epub 2014 Apr 24.

40.

Rhinovirus and the developing lung.

Cox DW, Le Souëf PN.

Paediatr Respir Rev. 2014 Sep;15(3):268-74. doi: 10.1016/j.prrv.2014.03.002. Epub 2014 Mar 27. Review.

PMID:
24767866
41.

Birth cohorts in asthma and allergic diseases: report of a NIAID/NHLBI/MeDALL joint workshop.

Bousquet J, Gern JE, Martinez FD, Anto JM, Johnson CC, Holt PG, Lemanske RF Jr, Le Souëf PN, Tepper RS, von Mutius ER, Arshad SH, Bacharier LB, Becker A, Belanger K, Bergström A, Bernstein DI, Cabana MD, Carroll KN, Castro M, Cooper PJ, Gillman MW, Gold DR, Henderson J, Heinrich J, Hong SJ, Jackson DJ, Keil T, Kozyrskyj AL, Lødrup Carlsen KC, Miller RL, Momas I, Morgan WJ, Noel P, Ownby DR, Pinart M, Ryan PH, Schwaninger JM, Sears MR, Simpson A, Smit HA, Stern DA, Subbarao P, Valenta R, Wang X, Weiss ST, Wood R, Wright AL, Wright RJ, Togias A, Gergen PJ.

J Allergy Clin Immunol. 2014 Jun;133(6):1535-46. doi: 10.1016/j.jaci.2014.01.018. Epub 2014 Mar 15.

42.

EAACI position statement on asthma exacerbations and severe asthma.

Custovic A, Johnston SL, Pavord I, Gaga M, Fabbri L, Bel EH, Le Souëf P, Lötvall J, Demoly P, Akdis CA, Ryan D, Mäkelä MJ, Martinez F, Holloway JW, Saglani S, O'Byrne P, Papi A, Sergejeva S, Magnan A, Del Giacco S, Kalayci O, Hamelmann E, Papadopoulos NG.

Allergy. 2013 Dec;68(12):1520-31. doi: 10.1111/all.12275. Epub 2013 Nov 6. Review.

PMID:
24410781
43.

Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.

Ferreira MA, Matheson MC, Tang CS, Granell R, Ang W, Hui J, Kiefer AK, Duffy DL, Baltic S, Danoy P, Bui M, Price L, Sly PD, Eriksson N, Madden PA, Abramson MJ, Holt PG, Heath AC, Hunter M, Musk B, Robertson CF, Le Souëf P, Montgomery GW, Henderson AJ, Tung JY, Dharmage SC, Brown MA, James A, Thompson PJ, Pennell C, Martin NG, Evans DM, Hinds DA, Hopper JL; Australian Asthma Genetics Consortium Collaborators.

J Allergy Clin Immunol. 2014 Jun;133(6):1564-71. doi: 10.1016/j.jaci.2013.10.030. Epub 2013 Dec 31.

44.

Impact of CD14 promoter variants on measles vaccine responses and vaccine failure in children from Australia and Mozambique.

Clifford HD, Hayden CM, Khoo SK, Naniche D, Mandomando IM, Zhang G, Richmond P, Le Souëf PN.

Tissue Antigens. 2013 Dec;82(6):420-2. doi: 10.1111/tan.12226. Epub 2013 Oct 21. No abstract available.

PMID:
24147858
45.

Human rhinovirus species C infection in young children with acute wheeze is associated with increased acute respiratory hospital admissions.

Cox DW, Bizzintino J, Ferrari G, Khoo SK, Zhang G, Whelan S, Lee WM, Bochkov YA, Geelhoed GC, Goldblatt J, Gern JE, Laing IA, Le Souëf PN.

Am J Respir Crit Care Med. 2013 Dec 1;188(11):1358-64. doi: 10.1164/rccm.201303-0498OC.

46.

Correction: Genome-Wide Association Studies of Asthma in Population-Based Cohorts Confirm Known and Suggested Loci and Identify an Additional Association near HLA.

Ramasamy A, Kuokkanen M, Vedantam S, Gajdos ZK, Couto Alves A, Lyon HN, Ferreira MAR, Strachan DP, Zhao JH, Abramson MJ, Brown MA, Coin L, Dharmage SC, Duffy DL, Haahtela T, Heath AC, Janson C, Kähönen M, Khaw KT, Laitinen J, Le Souef P, Lehtimäki T; Australian Asthma Genetics Consortium collaborators, Madden PAF, Marks GB, Martin NG, Matheson MC, Palmer CD, Palotie A, Pouta A, Robertson CF, Viikari J, Widen E, Wjst M, Jarvis DL, Montgomery GW, Thompson PJ, Wareham N, Eriksson J, Jousilahti P, Laitinen T, Pekkanen J, Raitakari OT, O'Connor GT, Salomaa V, Jarvelin MR, Hirschhorn JN.

PLoS One. 2013 Mar 4;8(3). doi: 10.1371/annotation/9630862b-4676-4b82-9869-8d8fbb2a2e65. eCollection 2013.

47.

A Dysmorphometric Analysis to Investigate Facial Phenotypic Signatures as a Foundation for Non-invasive Monitoring of Lysosomal Storage Disorders.

Kung S, Walters M, Claes P, Goldblatt J, Le Souef P, Baynam G.

JIMD Rep. 2013;8:31-9. doi: 10.1007/8904_2012_152. Epub 2012 Jun 10.

48.

Reduced infant lung function, active smoking, and wheeze in 18-year-old individuals.

Mullane D, Turner SW, Cox DW, Goldblatt J, Landau LI, le Souëf PN.

JAMA Pediatr. 2013 Apr;167(4):368-73. doi: 10.1001/jamapediatrics.2013.633. Erratum in: JAMA Pediatr. 2013 Sep;167(9):873. Cox, Des [corrected to Cox, Des W].

49.

Usefulness of parental response to questions about adherence to prescribed inhaled corticosteroids in young children.

Schultz A, Sly PD, Zhang G, Venter A, Devadason SG, le Souëf PN.

Arch Dis Child. 2012 Dec;97(12):1092-6. doi: 10.1136/archdischild-2012-302312. Epub 2012 Oct 25.

PMID:
23100609
50.

Genome-wide association studies of asthma in population-based cohorts confirm known and suggested loci and identify an additional association near HLA.

Ramasamy A, Kuokkanen M, Vedantam S, Gajdos ZK, Couto Alves A, Lyon HN, Ferreira MA, Strachan DP, Zhao JH, Abramson MJ, Brown MA, Coin L, Dharmage SC, Duffy DL, Haahtela T, Heath AC, Janson C, Kähönen M, Khaw KT, Laitinen J, Le Souef P, Lehtimäki T; Australian Asthma Genetics Consortium Collaborators, Madden PA, Marks GB, Martin NG, Matheson MC, Palmer CD, Palotie A, Pouta A, Robertson CF, Viikari J, Widen E, Wjst M, Jarvis DL, Montgomery GW, Thompson PJ, Wareham N, Eriksson J, Jousilahti P, Laitinen T, Pekkanen J, Raitakari OT, O'Connor GT, Salomaa V, Jarvelin MR, Hirschhorn JN.

PLoS One. 2012;7(9):e44008. doi: 10.1371/journal.pone.0044008. Epub 2012 Sep 28. Erratum in: PLoS One. 2013 Mar 4;8(3):.

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