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The Philani MOVIE study: a cluster-randomized controlled trial of a mobile video entertainment-education intervention to promote exclusive breastfeeding in South Africa.

Adam M, Tomlinson M, Le Roux I, LeFevre AE, McMahon SA, Johnston J, Kirton A, Mbewu N, Strydom SL, Prober C, Bärnighausen T.

BMC Health Serv Res. 2019 Apr 2;19(1):211. doi: 10.1186/s12913-019-4000-x.


Perinatal maternal depression in rural South Africa: Child outcomes over the first two years.

Christodoulou J, Le Roux K, Tomlinson M, Le Roux IM, Katzen LS, Rotheram-Borus MJ.

J Affect Disord. 2019 Mar 15;247:168-174. doi: 10.1016/j.jad.2019.01.019. Epub 2019 Jan 15.


A longitudinal cohort study of rural adolescent vs adult South African mothers and their children from birth to 24 months.

le Roux K, Christodoulou J, Stansert-Katzen L, Dippenaar E, Laurenzi C, le Roux IM, Tomlinson M, Rotheram-Borus MJ.

BMC Pregnancy Childbirth. 2019 Jan 11;19(1):24. doi: 10.1186/s12884-018-2164-8.


A recurrent point mutation in PRKCA is a hallmark of chordoid gliomas.

Rosenberg S, Simeonova I, Bielle F, Verreault M, Bance B, Le Roux I, Daniau M, Nadaradjane A, Gleize V, Paris S, Marie Y, Giry M, Polivka M, Figarella-Branger D, Aubriot-Lorton MH, Villa C, Vasiljevic A, Lechapt-Zalcman E, Kalamarides M, Sharif A, Mokhtari K, Pagnotta SM, Iavarone A, Lasorella A, Huillard E, Sanson M.

Nat Commun. 2018 Jun 18;9(1):2371. doi: 10.1038/s41467-018-04622-w.


Community health workers' experiences of using video teaching tools during home visits-A pilot study.

Coetzee B, Kohrman H, Tomlinson M, Mbewu N, Le Roux I, Adam M.

Health Soc Care Community. 2018 Mar;26(2):167-175. doi: 10.1111/hsc.12488. Epub 2017 Sep 5.


To evaluate if increased supervision and support of South African Government health workers' home visits improves maternal and child outcomes: study protocol for a randomized control trial.

Rotheram-Borus MJ, Le Roux K, Le Roux IM, Christodoulou J, Laurenzi C, Mbewu N, Tomlinson M.

Trials. 2017 Aug 7;18(1):368. doi: 10.1186/s13063-017-2074-5.


Antenatal depressed mood and child cognitive and physical growth at 18-months in South Africa: a cluster randomised controlled trial of home visiting by community health workers.

Tomlinson M, Rotheram-Borus MJ, Scheffler A, le Roux I.

Epidemiol Psychiatr Sci. 2018 Dec;27(6):601-610. doi: 10.1017/S2045796017000257. Epub 2017 Jun 13.


Injury-Induced Senescence Enables In Vivo Reprogramming in Skeletal Muscle.

Chiche A, Le Roux I, von Joest M, Sakai H, Aguín SB, Cazin C, Salam R, Fiette L, Alegria O, Flamant P, Tajbakhsh S, Li H.

Cell Stem Cell. 2017 Mar 2;20(3):407-414.e4. doi: 10.1016/j.stem.2016.11.020. Epub 2016 Dec 22.


Thirty-Six-Month Outcomes of a Generalist Paraprofessional Perinatal Home Visiting Intervention in South Africa on Maternal Health and Child Health and Development.

Tomlinson M, Rotheram-Borus MJ, le Roux IM, Youssef M, Nelson SH, Scheffler A, Weiss RE, O'Connor M, Worthman CM.

Prev Sci. 2016 Nov;17(8):937-948.


The Philani Mentor Mothers Intervention: Neighbourhood wide impact on child growth in Cape Town's peri-urban settlements.

Tomlinson M, Hartley M, le Roux I, Rotheram-Borus MJ.

Vulnerable Child Youth Stud. 2016;11(3):221-222. doi: 10.1080/17450128.2016.1220658. Epub 2016 Aug 30.


Numb is required to prevent p53-dependent senescence following skeletal muscle injury.

Le Roux I, Konge J, Le Cam L, Flamant P, Tajbakhsh S.

Nat Commun. 2015 Oct 27;6:8528. doi: 10.1038/ncomms9528.


Community health workers can improve child growth of antenatally-depressed, South African mothers: a cluster randomized controlled trial.

Tomlinson M, Rotheram-Borus MJ, Harwood J, le Roux IM, O'Connor M, Worthman C.

BMC Psychiatry. 2015 Sep 23;15:225. doi: 10.1186/s12888-015-0606-7.


The Role of Community Health Workers in the Re-Engineering of Primary Health Care in Rural Eastern Cape.

le Roux K, le Roux I, Mbewu N, Davis E.

S Afr Fam Pract (2004). 2015 Mar 1;57(2):116-120.


Re-engagement in HIV care among mothers living with HIV in South Africa over 36 months post-birth.

Rotheram-Borus MJ, Tomlinson M, Scheffler A, Le Roux IM.

AIDS. 2015 Nov;29(17):2361-2. doi: 10.1097/QAD.0000000000000837.


The impact of paraprofessional home visitors on infants' growth and health at 18 months.

le Roux IM, Rotheram-Borus MJ, Stein J, Tomlinson M.

Vulnerable Child Youth Stud. 2014 Jan 1;9(4):291-304.


A cluster randomised controlled effectiveness trial evaluating perinatal home visiting among South African mothers/infants.

Rotheram-Borus MJ, Tomlinson M, le Roux IM, Harwood JM, Comulada S, O'Connor MJ, Weiss RE, Worthman CM.

PLoS One. 2014 Oct 23;9(10):e105934. doi: 10.1371/journal.pone.0105934. eCollection 2014.


Community-based prenatal screening for postpartum depression in a South African township.

Hung KJ, Tomlinson M, le Roux IM, Dewing S, Chopra M, Tsai AC.

Int J Gynaecol Obstet. 2014 Jul;126(1):74-7. doi: 10.1016/j.ijgo.2014.01.011. Epub 2014 Apr 2.


Antenatal depression case finding by community health workers in South Africa: feasibility of a mobile phone application.

Tsai AC, Tomlinson M, Dewing S, le Roux IM, Harwood JM, Chopra M, Rotheram-Borus MJ.

Arch Womens Ment Health. 2014 Oct;17(5):423-31. doi: 10.1007/s00737-014-0426-7. Epub 2014 Mar 30.


Food insecurity and its association with co-occurring postnatal depression, hazardous drinking, and suicidality among women in peri-urban South Africa.

Dewing S, Tomlinson M, le Roux IM, Chopra M, Tsai AC.

J Affect Disord. 2013 Sep 5;150(2):460-5. doi: 10.1016/j.jad.2013.04.040. Epub 2013 May 23.


Embryonic founders of adult muscle stem cells are primed by the determination gene Mrf4.

Sambasivan R, Comai G, Le Roux I, Gomès D, Konge J, Dumas G, Cimper C, Tajbakhsh S.

Dev Biol. 2013 Sep 1;381(1):241-55. doi: 10.1016/j.ydbio.2013.04.018. Epub 2013 Apr 25.


Multiple risk factors during pregnancy in South Africa: the need for a horizontal approach to perinatal care.

Tomlinson M, O'Connor MJ, le Roux IM, Stewart J, Mbewu N, Harwood J, Rotheram-Borus MJ.

Prev Sci. 2014 Jun;15(3):277-82. doi: 10.1007/s11121-013-0376-8.


Outcomes of home visits for pregnant mothers and their infants: a cluster randomized controlled trial.

le Roux IM, Tomlinson M, Harwood JM, O'Connor MJ, Worthman CM, Mbewu N, Stewart J, Hartley M, Swendeman D, Comulada WS, Weiss RE, Rotheram-Borus MJ.

AIDS. 2013 Jun 1;27(9):1461-71. doi: 10.1097/QAD.0b013e3283601b53.


Value of a mobile information system to improve quality of care by community health workers.

Tomlinson M, Rotheram-Borus MJ, Doherty T, Swendeman D, Tsai AC, Ijumba P, le Roux I, Jackson D, Stewart J, Friedman A, Colvin M, Chopra M.

S Afr J Inf Manag. 2013;15(1). doi: 10.4102/sajim.v15i1.528.


A randomized controlled trial of home visits by neighborhood mentor mothers to improve children's nutrition in South Africa.

le Roux IM, le Roux K, Mbeutu K, Comulada WS, Desmond KA, Rotheram-Borus MJ.

Vulnerable Child Youth Stud. 2011 Jun;6(2):91-102. Epub 2011 Jun 28.


Philani Plus (+): a Mentor Mother community health worker home visiting program to improve maternal and infants' outcomes.

Rotheram-Borus MJ, le Roux IM, Tomlinson M, Mbewu N, Comulada WS, le Roux K, Stewart J, O'Connor MJ, Hartley M, Desmond K, Greco E, Worthman CM, Idemundia F, Swendeman D.

Prev Sci. 2011 Dec;12(4):372-88. doi: 10.1007/s11121-011-0238-1.


Depressed mood in pregnancy: prevalence and correlates in two Cape Town peri-urban settlements.

Hartley M, Tomlinson M, Greco E, Comulada WS, Stewart J, le Roux I, Mbewu N, Rotheram-Borus MJ.

Reprod Health. 2011 May 2;8:9. doi: 10.1186/1742-4755-8-9.


Home visits by neighborhood Mentor Mothers provide timely recovery from childhood malnutrition in South Africa: results from a randomized controlled trial.

le Roux IM, le Roux K, Comulada WS, Greco EM, Desmond KA, Mbewu N, Rotheram-Borus MJ.

Nutr J. 2010 Nov 22;9:56. doi: 10.1186/1475-2891-9-56.


No emergence of Echinococcus multilocularis in foxes in Flanders and Brussels anno 2007-2008.

Van Gucht S, Van Den Berge K, Quataert P, Verschelde P, Le Roux I.

Zoonoses Public Health. 2010 Dec;57(7-8):e65-70. doi: 10.1111/j.1863-2378.2009.01322.x.


Numb promotes an increase in skeletal muscle progenitor cells in the embryonic somite.

Jory A, Le Roux I, Gayraud-Morel B, Rocheteau P, Cohen-Tannoudji M, Cumano A, Tajbakhsh S.

Stem Cells. 2009 Nov;27(11):2769-80. doi: 10.1002/stem.220.


Early mouse caudal development relies on crosstalk between retinoic acid, Shh and Fgf signalling pathways.

Ribes V, Le Roux I, Rhinn M, Schuhbaur B, Dollé P.

Development. 2009 Feb;136(4):665-76. doi: 10.1242/dev.016204.


Combinatorial signalling controls Neurogenin2 expression at the onset of spinal neurogenesis.

Ribes V, Stutzmann F, Bianchetti L, Guillemot F, Dollé P, Le Roux I.

Dev Biol. 2008 Sep 15;321(2):470-81. doi: 10.1016/j.ydbio.2008.06.003. Epub 2008 Jun 13.


Asymmetric cell divisions and asymmetric cell fates.

Tajbakhsh S, Rocheteau P, Le Roux I.

Annu Rev Cell Dev Biol. 2009;25:671-99. doi: 10.1146/annurev.cellbio.24.110707.175415. Review.


Retinaldehyde dehydrogenase 2 and Hoxc8 are required in the murine brachial spinal cord for the specification of Lim1+ motoneurons and the correct distribution of Islet1+ motoneurons.

Vermot J, Schuhbaur B, Le Mouellic H, McCaffery P, Garnier JM, Hentsch D, Brûlet P, Niederreither K, Chambon P, Dollé P, Le Roux I.

Development. 2005 Apr;132(7):1611-21.


Stat3 signaling is present and active during development of the central nervous system and eye of vertebrates.

Yan Y, Bian W, Xie Z, Cao X, Le Roux I, Guillemot F, Jing N.

Dev Dyn. 2004 Oct;231(2):248-57.


Medical Compliance and Income-Health Gradients.

Case A, Le Roux I, Menendez A.

Am Econ Rev. 2004;94(2):331-5. No abstract available.


Direct and concentration-dependent regulation of the proneural gene Neurogenin2 by Pax6.

Scardigli R, Bäumer N, Gruss P, Guillemot F, Le Roux I.

Development. 2003 Jul;130(14):3269-81.


The regional pattern of retinoic acid synthesis by RALDH2 is essential for the development of posterior pharyngeal arches and the enteric nervous system.

Niederreither K, Vermot J, Le Roux I, Schuhbaur B, Chambon P, Dollé P.

Development. 2003 Jun;130(11):2525-34.


A floor plate enhancer of the zebrafish netrin1 gene requires Cyclops (Nodal) signalling and the winged helix transcription factor FoxA2.

Rastegar S, Albert S, Le Roux I, Fischer N, Blader P, Müller F, Strähle U.

Dev Biol. 2002 Dec 1;252(1):1-14.


A proposed vitamin A supplementation programme for South Africa--design, coverage and cost.

Saitowitz R, Hendricks M, Fiedler J, le Roux I, Hussey G, Makan B.

S Afr Med J. 2001 Sep;91(9):755-60.


Notch signaling in the development of the inner ear: lessons from Drosophila.

Eddison M, Le Roux I, Lewis J.

Proc Natl Acad Sci U S A. 2000 Oct 24;97(22):11692-9.


Sensory organ generation in the chicken inner ear: contributions of bone morphogenetic protein 4, serrate1, and lunatic fringe.

Cole LK, Le Roux I, Nunes F, Laufer E, Lewis J, Wu DK.

J Comp Neurol. 2000 Aug 28;424(3):509-20.


Stimulation of human epidermal differentiation by delta-notch signalling at the boundaries of stem-cell clusters.

Lowell S, Jones P, Le Roux I, Dunne J, Watt FM.

Curr Biol. 2000 May 4;10(9):491-500.


Serrate1-induced notch signalling regulates the decision between immunity and tolerance made by peripheral CD4(+) T cells.

Hoyne GF, Le Roux I, Corsin-Jimenez M, Tan K, Dunne J, Forsyth LM, Dallman MJ, Owen MJ, Ish-Horowicz D, Lamb JR.

Int Immunol. 2000 Feb;12(2):177-85.


Cell fate choices and the expression of Notch, Delta and Serrate homologues in the chick inner ear: parallels with Drosophila sense-organ development.

Adam J, Myat A, Le Roux I, Eddison M, Henrique D, Ish-Horowicz D, Lewis J.

Development. 1998 Dec;125(23):4645-54.


The Notch ligand, Jagged-1, influences the development of primitive hematopoietic precursor cells.

Varnum-Finney B, Purton LE, Yu M, Brashem-Stein C, Flowers D, Staats S, Moore KA, Le Roux I, Mann R, Gray G, Artavanis-Tsakonas S, Bernstein ID.

Blood. 1998 Jun 1;91(11):4084-91.


Maintenance of neuroepithelial progenitor cells by Delta-Notch signalling in the embryonic chick retina.

Henrique D, Hirsinger E, Adam J, Le Roux I, Pourquié O, Ish-Horowicz D, Lewis J.

Curr Biol. 1997 Sep 1;7(9):661-70.


Half-body irradiation in multiple myeloma.

Jacobs P, Johnson C, le Roux I.

S Afr Med J. 1995 Dec;85(12):1308. No abstract available.


Promoter-specific regulation of gene expression by an exogenously added homedomain that promotes neurite growth.

Le Roux I, Duharcourt S, Volovitch M, Prochiantz A, Ronchi E.

FEBS Lett. 1995 Jul 17;368(2):311-4.

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