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The role of Glial cell derived neurotrophic factor in head and neck cancer.

Cao H, He Q, Eyben RV, Bloomstein J, Nambiar DK, Viswanathan V, Aggarwal S, Kwok S, Liang R, Koong AJ, Lewis JS Jr, Kong C, Xiao N, Le QT.

PLoS One. 2020 Feb 21;15(2):e0229311. doi: 10.1371/journal.pone.0229311. eCollection 2020.


Comments on the Publication by Corkum et al on "Does 5 + 5 mm Equal Better Radiation Treatment Plans in Head and Neck Cancers?"

Grégoire V, Grau C, Le QT, Yom SS; Head and Neck Intergroup.

Adv Radiat Oncol. 2020 Jan 1;5(1):140-141. doi: 10.1016/j.adro.2019.08.011. eCollection 2020 Jan-Feb. No abstract available.


Gelless Secondary Growth of Zeolitic Aluminophosphate Membranes on Porous Supports with High Performance in CO2 /CH4 Separation.

Le QT, Nguyen DH, Nguyen NM, Nguyen DP, Nguyen TM, Nguyen TN, Pham TC.

ChemSusChem. 2020 Jan 13. doi: 10.1002/cssc.201903571. [Epub ahead of print]


Proton radiotherapy and treatment delay in head and neck squamous cell carcinoma.

Jin MC, Harris JP, Sabolch AN, Gensheimer M, Le QT, Beadle BM, Pollom EL.

Laryngoscope. 2019 Dec 14. doi: 10.1002/lary.28458. [Epub ahead of print]


Association analysis of phenotypic and metabolomic changes in Arabidopsis accessions and their F1 hybrids affected by different photoperiod and sucrose supply.

Le QTN, Sugi N, Furukawa J, Kobayashi M, Saito K, Kusano M, Shiba H.

Plant Biotechnol (Tokyo). 2019 Sep 25;36(3):155-165. doi: 10.5511/plantbiotechnology.19.0604a.


Galectin-1-driven T cell exclusion in the tumor endothelium promotes immunotherapy resistance.

Nambiar DK, Aguilera T, Cao H, Kwok S, Kong C, Bloomstein J, Wang Z, Rangan VS, Jiang D, von Eyben R, Liang R, Agarwal S, Colevas AD, Korman A, Allen CT, Uppaluri R, Koong AC, Giaccia A, Le QT.

J Clin Invest. 2019 Dec 2;129(12):5553-5567. doi: 10.1172/JCI129025.


Decreased glomerular filtration rate in patients with at least 5 years of type 2 diabetes in Ho Chi Minh City, Vietnam: Prevalence and associated factors.

Le HT, Le TT, Tran NMT, Nguyen TTT, Minh NCS, Le QT, Tram TAT, Tran TD, Doan TX, Thai TT.

Prim Care Diabetes. 2019 Sep 4. pii: S1751-9918(19)30180-9. doi: 10.1016/j.pcd.2019.08.003. [Epub ahead of print]


Lambda-Carrageenan Enhances the Effects of Radiation Therapy in Cancer Treatment by Suppressing Cancer Cell Invasion and Metastasis through Racgap1 Inhibition.

Wu PH, Onodera Y, Recuenco FC, Giaccia AJ, Le QT, Shimizu S, Shirato H, Nam JM.

Cancers (Basel). 2019 Aug 16;11(8). pii: E1192. doi: 10.3390/cancers11081192.


Tumor Subregion Evolution-based Imaging Features to Assess Early Response and Predict Prognosis in Oropharyngeal Cancer.

Wu J, Gensheimer M, Zhang N, Guo M, Liang R, Zhang C, Fischbein N, Pollom E, Beadle B, Le QT, Li R.

J Nucl Med. 2019 Aug 16. pii: jnumed.119.230037. doi: 10.2967/jnumed.119.230037. [Epub ahead of print]


Nomogram to Predict the Benefit of Intensive Treatment for Locoregionally Advanced Head and Neck Cancer.

Mell LK, Shen H, Nguyen-Tân PF, Rosenthal DI, Zakeri K, Vitzthum LK, Frank SJ, Schiff PB, Trotti AM 3rd, Bonner JA, Jones CU, Yom SS, Thorstad WL, Wong SJ, Shenouda G, Ridge JA, Zhang QE, Le QT.

Clin Cancer Res. 2019 Dec 1;25(23):7078-7088. doi: 10.1158/1078-0432.CCR-19-1832. Epub 2019 Aug 16.


Role of chemotherapy in 5000 patients with head and neck cancer treated by curative surgery: A subgroup analysis of the meta-analysis of chemotherapy in head and neck cancer.

Dauzier E, Lacas B, Blanchard P, Le QT, Simon C, Wolf G, Janot F, Horiuchi M, Tobias JS, Moon J, Simes J, Deshmane V, Mazeron JJ, Mehta S, Zaktonik B, Tamura M, Moyal E, Licitra L, Fortpied C, Haffty BG, Ghi MG, Gregoire V, Harris J, Bourhis J, Aupérin A, Pignon JP; MACH-NC Collaborative Group.

Oral Oncol. 2019 Aug;95:106-114. doi: 10.1016/j.oraloncology.2019.06.001. Epub 2019 Jun 15.


Impact of naturally forming human α/β-tryptase heterotetramers in the pathogenesis of hereditary α-tryptasemia.

Le QT, Lyons JJ, Naranjo AN, Olivera A, Lazarus RA, Metcalfe DD, Milner JD, Schwartz LB.

J Exp Med. 2019 Oct 7;216(10):2348-2361. doi: 10.1084/jem.20190701. Epub 2019 Jul 23.


Radiographic Extranodal Extension in Human Papillomavirus-Associated Oropharyngeal Carcinoma: Can it Help Tailor Treatment?

Gensheimer MF, Le QT.

Int J Radiat Oncol Biol Phys. 2019 Aug 1;104(5):1028-1029. doi: 10.1016/j.ijrobp.2019.05.022. No abstract available.


The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of squamous cell carcinoma of the head and neck (HNSCC).

Cohen EEW, Bell RB, Bifulco CB, Burtness B, Gillison ML, Harrington KJ, Le QT, Lee NY, Leidner R, Lewis RL, Licitra L, Mehanna H, Mell LK, Raben A, Sikora AG, Uppaluri R, Whitworth F, Zandberg DP, Ferris RL.

J Immunother Cancer. 2019 Jul 15;7(1):184. doi: 10.1186/s40425-019-0662-5.


International Guideline on Dose Prioritization and Acceptance Criteria in Radiation Therapy Planning for Nasopharyngeal Carcinoma.

Lee AW, Ng WT, Pan JJ, Chiang CL, Poh SS, Choi HC, Ahn YC, AlHussain H, Corry J, Grau C, Grégoire V, Harrington KJ, Hu CS, Kwong DL, Langendijk JA, Le QT, Lee NY, Lin JC, Lu TX, Mendenhall WM, O'Sullivan B, Ozyar E, Peters LJ, Rosenthal DI, Sanguineti G, Soong YL, Tao Y, Yom SS, Wee JT.

Int J Radiat Oncol Biol Phys. 2019 Nov 1;105(3):567-580. doi: 10.1016/j.ijrobp.2019.06.2540. Epub 2019 Jul 2. Erratum in: Int J Radiat Oncol Biol Phys. 2019 Dec 1;105(5):1166-1167.


The changing therapeutic landscape of head and neck cancer.

Cramer JD, Burtness B, Le QT, Ferris RL.

Nat Rev Clin Oncol. 2019 Nov;16(11):669-683. doi: 10.1038/s41571-019-0227-z. Epub 2019 Jun 12. Review.


Nasopharyngeal carcinoma.

Chen YP, Chan ATC, Le QT, Blanchard P, Sun Y, Ma J.

Lancet. 2019 Jul 6;394(10192):64-80. doi: 10.1016/S0140-6736(19)30956-0. Epub 2019 Jun 6. Review.


Biological Activities and Chemical Constituents of Essential Oils from Piper cubeba Bojer and Piper nigrum L.

Andriana Y, Xuan TD, Quy TN, Tran HD, Le QT.

Molecules. 2019 May 15;24(10). pii: E1876. doi: 10.3390/molecules24101876.


Role of Treatment Deintensification in the Management of p16+ Oropharyngeal Cancer: ASCO Provisional Clinical Opinion.

Adelstein DJ, Ismaila N, Ku JA, Burtness B, Swiecicki PL, Mell L, Beitler JJ, Gross N, Jones CU, Kaufman M, Le QT, Semrad TJ, Siu LL, Ridge JA.

J Clin Oncol. 2019 Jun 20;37(18):1578-1589. doi: 10.1200/JCO.19.00441. Epub 2019 Apr 25.


Integrating Tumor and Nodal Imaging Characteristics at Baseline and Mid-Treatment Computed Tomography Scans to Predict Distant Metastasis in Oropharyngeal Cancer Treated With Concurrent Chemoradiotherapy.

Wu J, Gensheimer MF, Zhang N, Han F, Liang R, Qian Y, Zhang C, Fischbein N, Pollom EL, Beadle B, Le QT, Li R.

Int J Radiat Oncol Biol Phys. 2019 Jul 15;104(4):942-952. doi: 10.1016/j.ijrobp.2019.03.036. Epub 2019 Mar 30.


Validation of NRG oncology/RTOG-0129 risk groups for HPV-positive and HPV-negative oropharyngeal squamous cell cancer: Implications for risk-based therapeutic intensity trials.

Fakhry C, Zhang Q, Gillison ML, Nguyen-Tân PF, Rosenthal DI, Weber RS, Lambert L, Trotti AM 3rd, Barrett WL, Thorstad WL, Yom SS, Wong SJ, Ridge JA, Rao SSD, Spencer S, Fortin A, Raben D, Harris J, Le QT.

Cancer. 2019 Jun 15;125(12):2027-2038. doi: 10.1002/cncr.32025. Epub 2019 Mar 26.


Current Treatment Landscape of Nasopharyngeal Carcinoma and Potential Trials Evaluating the Value of Immunotherapy.

Le QT, Colevas AD, O'Sullivan B, Lee AWM, Lee N, Ma B, Siu LL, Waldron J, Lim CM, Riaz N, Lynn J, Malik S.

J Natl Cancer Inst. 2019 Mar 26. pii: djz044. doi: 10.1093/jnci/djz044. [Epub ahead of print]


Cost-effectiveness of Screening for Nasopharyngeal Carcinoma among Asian American Men in the United States.

Harris JP, Saraswathula A, Kaplun B, Qian Y, Chan KCA, Chan ATC, Le QT, Owens DK, Goldhaber-Fiebert JD, Pollom E.

Otolaryngol Head Neck Surg. 2019 Jul;161(1):82-90. doi: 10.1177/0194599819832593. Epub 2019 Mar 5.


Increased Galectin-1 Expression in Thymic Epithelial Tumors.

Riess JW, Kong CS, West RB, Padda SK, Neal JW, Wakelee HA, Le QT.

Clin Lung Cancer. 2019 May;20(3):e356-e361. doi: 10.1016/j.cllc.2018.12.005. Epub 2018 Dec 21.


Characterization of the Transglycosylation Reaction of 4-α-Glucanotransferase (MalQ) and Its Role in Glycogen Breakdown in Escherichia coli.

Nguyen DHD, Park SH, Tran PL, Kim JW, Le QT, Boos W, Park JT.

J Microbiol Biotechnol. 2019 Mar 28;29(3):357-366. doi: 10.4014/jmb.1811.11051.


Smoking, age, nodal disease, T stage, p16 status, and risk of distant metastases in patients with squamous cell cancer of the oropharynx.

Beitler JJ, Switchenko JM, Dignam JJ, McDonald MW, Saba NF, Shin DM, Magliocca KR, Cassidy RJ, El-Deiry MW, Patel MR, Steuer CE, Xiao C, Hudgins PA, Aiken AH, Curran WJ Jr, Le QT.

Cancer. 2019 Mar 1;125(5):704-711. doi: 10.1002/cncr.31820. Epub 2018 Dec 11.


The use of texture-based radiomics CT analysis to predict outcomes in early-stage non-small cell lung cancer treated with stereotactic ablative radiotherapy.

Starkov P, Aguilera TA, Golden DI, Shultz DB, Trakul N, Maxim PG, Le QT, Loo BW, Diehn M, Depeursinge A, Rubin DL.

Br J Radiol. 2019 Feb;92(1094):20180228. doi: 10.1259/bjr.20180228. Epub 2018 Nov 20.


Radiotherapy plus cetuximab or cisplatin in human papillomavirus-positive oropharyngeal cancer (NRG Oncology RTOG 1016): a randomised, multicentre, non-inferiority trial.

Gillison ML, Trotti AM, Harris J, Eisbruch A, Harari PM, Adelstein DJ, Sturgis EM, Burtness B, Ridge JA, Ringash J, Galvin J, Yao M, Koyfman SA, Blakaj DM, Razaq MA, Colevas AD, Beitler JJ, Jones CU, Dunlap NE, Seaward SA, Spencer S, Galloway TJ, Phan J, Dignam JJ, Le QT.

Lancet. 2019 Jan 5;393(10166):40-50. doi: 10.1016/S0140-6736(18)32779-X. Epub 2018 Nov 15.


Adaptive radiotherapy for head and neck cancer: Are we ready to put it into routine clinical practice?

Gensheimer MF, Le QT.

Oral Oncol. 2018 Nov;86:19-24. doi: 10.1016/j.oraloncology.2018.08.010. Epub 2018 Sep 10. Review.


Identification and validation of novel microenvironment-based immune molecular subgroups of head and neck squamous cell carcinoma: implications for immunotherapy.

Chen YP, Wang YQ, Lv JW, Li YQ, Chua MLK, Le QT, Lee N, Colevas AD, Seiwert T, Hayes DN, Riaz N, Vermorken JB, O'Sullivan B, He QM, Yang XJ, Tang LL, Mao YP, Sun Y, Liu N, Ma J.

Ann Oncol. 2019 Jan 1;30(1):68-75. doi: 10.1093/annonc/mdy470.


Focus on the Number of Radiation Oncology Trials or on Clinical Relevance-Reply.

Liu X, Le QT, Ma J.

JAMA Oncol. 2018 Dec 1;4(12):1791-1792. doi: 10.1001/jamaoncol.2018.5105. No abstract available.


Factors associated with a low prevalence of exclusive breastfeeding during hospital stay in urban and semi-rural areas of southern Vietnam.

Le QT, Phung KL, Nguyen VT, Anders KL, Nguyen MN, Hoang DT, Bui TT, Nguyen VV, Thwaites GE, Simmons C, Baker S.

Int Breastfeed J. 2018 Oct 19;13:46. doi: 10.1186/s13006-018-0188-3. eCollection 2018.


A pooled analysis of individual patient data from National Clinical Trials Network clinical trials of concurrent chemoradiotherapy for limited-stage small cell lung cancer in elderly patients versus younger patients.

Stinchcombe TE, Fan W, Schild SE, Vokes EE, Bogart J, Le QT, Thomas CR, Edelman MJ, Horn L, Komaki R, Cohen HJ, Kishor Ganti A, Pang H, Wang X.

Cancer. 2019 Feb 1;125(3):382-390. doi: 10.1002/cncr.31813. Epub 2018 Oct 21.


Survival of patients with head and neck cancer treated with definitive radiotherapy and concurrent cisplatin or concurrent cetuximab: A Surveillance, Epidemiology, and End Results-Medicare analysis.

Xiang M, Holsinger FC, Colevas AD, Chen MM, Le QT, Beadle BM.

Cancer. 2018 Dec 1;124(23):4486-4494. doi: 10.1002/cncr.31708. Epub 2018 Oct 17.


In Regard to Bossi et al.

Fakhry C, Nguyen-Tân PF, Lambert L, Rosenthal DI, Weber RS, Gillison ML, Trotti AM 3rd, Barrett WL, Thorstad WL, Jones CU, Yom SS, Wong SJ, Ridge JA, Rao SSD, Bonner JA, Vigneault E, Raben D, Kudrimoti MR, Harris J, Le QT.

Int J Radiat Oncol Biol Phys. 2018 Nov 1;102(3):669-670. doi: 10.1016/j.ijrobp.2018.06.020. No abstract available.


Papaverine and its derivatives radiosensitize solid tumors by inhibiting mitochondrial metabolism.

Benej M, Hong X, Vibhute S, Scott S, Wu J, Graves E, Le QT, Koong AC, Giaccia AJ, Yu B, Chen CS, Papandreou I, Denko NC.

Proc Natl Acad Sci U S A. 2018 Oct 16;115(42):10756-10761. doi: 10.1073/pnas.1808945115. Epub 2018 Sep 10. Erratum in: Proc Natl Acad Sci U S A. 2018 Dec 4;115(49):E11561.


In Regard to Beadle and Anderson.

Le QT, Yom SS, Wee JTS, Lee AWM, Grau C, Grégoire V, Porceddu S, Welch JJ, Mehanna H.

Int J Radiat Oncol Biol Phys. 2018 Sep 1;102(1):229-230. doi: 10.1016/j.ijrobp.2018.05.015. Epub 2018 Aug 8. No abstract available.


Investigation of magnetic droplet solitons using x-ray holography with extended references.

Burgos-Parra E, Bukin N, Sani S, Figueroa AI, Beutier G, Dupraz M, Chung S, Dürrenfeld P, Le QT, Mohseni SM, Houshang A, Cavill SA, Hicken RJ, Åkerman J, van der Laan G, Ogrin FY.

Sci Rep. 2018 Aug 1;8(1):11533. doi: 10.1038/s41598-018-29856-y.


Feasibility of optimizing intensity-modulated radiation therapy plans based on measured mucosal dose adjacent to dental fillings and toxicity outcomes.

Seol SW, Aggarwal S, von Eyben R, Wang Z, Chan C, Say C, Xing L, Hara W, Yang Y, Le QT.

J Appl Clin Med Phys. 2018 Sep;19(5):444-452. doi: 10.1002/acm2.12407. Epub 2018 Jul 9.


Direct Observation of Zhang-Li Torque Expansion of Magnetic Droplet Solitons.

Chung S, Le QT, Ahlberg M, Awad AA, Weigand M, Bykova I, Khymyn R, Dvornik M, Mazraati H, Houshang A, Jiang S, Nguyen TNA, Goering E, Schütz G, Gräfe J, Åkerman J.

Phys Rev Lett. 2018 May 25;120(21):217204. doi: 10.1103/PhysRevLett.120.217204.


Characteristics of Radiotherapy Trials Compared With Other Oncological Clinical Trials in the Past 10 Years.

Liu X, Zhang Y, Tang LL, Le QT, Chua MLK, Wee JTS, Lee NY, O'Sullivan B, Lee AWM, Sun Y, Ma J.

JAMA Oncol. 2018 Aug 1;4(8):1073-1079. doi: 10.1001/jamaoncol.2018.0887.


Aldehyde dehydrogenase 3A1 activation prevents radiation-induced xerostomia by protecting salivary stem cells from toxic aldehydes.

Saiki JP, Cao H, Van Wassenhove LD, Viswanathan V, Bloomstein J, Nambiar DK, Mattingly AJ, Jiang D, Chen CH, Stevens MC, Simmons AL, Park HS, von Eyben R, Kool ET, Sirjani D, Knox SM, Le QT, Mochly-Rosen D.

Proc Natl Acad Sci U S A. 2018 Jun 12;115(24):6279-6284. doi: 10.1073/pnas.1802184115. Epub 2018 May 24.


Combining precision radiotherapy with molecular targeting and immunomodulatory agents: a guideline by the American Society for Radiation Oncology.

Bristow RG, Alexander B, Baumann M, Bratman SV, Brown JM, Camphausen K, Choyke P, Citrin D, Contessa JN, Dicker A, Kirsch DG, Krause M, Le QT, Milosevic M, Morris ZS, Sarkaria JN, Sondel PM, Tran PT, Wilson GD, Willers H, Wong RKS, Harari PM.

Lancet Oncol. 2018 May;19(5):e240-e251. doi: 10.1016/S1470-2045(18)30096-2. Review.


Workshop Report for Cancer Research: Defining the Shades of Gy: Utilizing the Biological Consequences of Radiotherapy in the Development of New Treatment Approaches-Meeting Viewpoint.

Ahmed MM, Coleman CN, Mendonca M, Bentzen S, Vikram B, Seltzer SM, Goodhead D, Obcemea C, Mohan R, Prise KM, Capala J, Citrin D, Kao G, Aryankalayil M, Eke I, Buchsbaum JC, Prasanna PGS, Liu FF, Le QT, Teicher B, Kirsch DG, Smart D, Tepper J, Formenti S, Haas-Kogan D, Raben D, Mitchell J.

Cancer Res. 2018 May 1;78(9):2166-2170. doi: 10.1158/0008-5472.CAN-17-3760. Epub 2018 Apr 23. No abstract available.


Mutational screening of germline RB1 gene in Vietnamese patients with retinoblastoma reveals three novel mutations.

Nguyen HH, Nguyen HTT, Vu NP, Le QT, Pham CM, Huyen TT, Manh H, Pham HLB, Nguyen TD, Le HTT, Van Nong H.

Mol Vis. 2018 Mar 17;24:231-238. eCollection 2018.


A Human Genome-Wide RNAi Screen Reveals Diverse Modulators that Mediate IRE1α-XBP1 Activation.

Yang Z, Zhang J, Jiang D, Khatri P, Solow-Cordero DE, Toesca DAS, Koumenis C, Denko NC, Giaccia AJ, Le QT, Koong AC.

Mol Cancer Res. 2018 May;16(5):745-753. doi: 10.1158/1541-7786.MCR-17-0307. Epub 2018 Feb 9.


Selection of external beam radiotherapy approaches for precise and accurate cancer treatment.

Shirato H, Le QT, Kobashi K, Prayongrat A, Takao S, Shimizu S, Giaccia A, Xing L, Umegaki K.

J Radiat Res. 2018 Mar 1;59(suppl_1):i2-i10. doi: 10.1093/jrr/rrx092.


Impact of anthropogenic activities on water quality and plankton communities in the Day River (Red River Delta, Vietnam).

Hoang HTT, Duong TT, Nguyen KT, Le QTP, Luu MTN, Trinh DA, Le AH, Ho CT, Dang KD, Némery J, Orange D, Klein J.

Environ Monit Assess. 2018 Jan 8;190(2):67. doi: 10.1007/s10661-017-6435-z.


Posterior Estimates of Dynamic Constants in HIV Transmission Modeling.

Chen Y, Dale R, He H, Le QT.

Comput Math Methods Med. 2017;2017:1093045. doi: 10.1155/2017/1093045. Epub 2017 Nov 7.


Future cancer research priorities in the USA: a Lancet Oncology Commission.

Jaffee EM, Dang CV, Agus DB, Alexander BM, Anderson KC, Ashworth A, Barker AD, Bastani R, Bhatia S, Bluestone JA, Brawley O, Butte AJ, Coit DG, Davidson NE, Davis M, DePinho RA, Diasio RB, Draetta G, Frazier AL, Futreal A, Gambhir SS, Ganz PA, Garraway L, Gerson S, Gupta S, Heath J, Hoffman RI, Hudis C, Hughes-Halbert C, Ibrahim R, Jadvar H, Kavanagh B, Kittles R, Le QT, Lippman SM, Mankoff D, Mardis ER, Mayer DK, McMasters K, Meropol NJ, Mitchell B, Naredi P, Ornish D, Pawlik TM, Peppercorn J, Pomper MG, Raghavan D, Ritchie C, Schwarz SW, Sullivan R, Wahl R, Wolchok JD, Wong SL, Yung A.

Lancet Oncol. 2017 Nov;18(11):e653-e706. doi: 10.1016/S1470-2045(17)30698-8. Epub 2017 Oct 31. Review.

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