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Items: 44

1.

Robust surgical approach for cutaneous neurofibroma in neurofibromatosis type 1.

Chamseddin BH, Hernandez L, Solorzano D, Vega J, Le LQ.

JCI Insight. 2019 Apr 30;5. pii: 128881. doi: 10.1172/jci.insight.128881.

2.

Overcoming BET Inhibitor Resistance in Malignant Peripheral Nerve Sheath Tumors.

Cooper JM, Patel AJ, Chen Z, Liao CP, Chen K, Mo J, Wang Y, Le LQ.

Clin Cancer Res. 2019 Jun 1;25(11):3404-3416. doi: 10.1158/1078-0432.CCR-18-2437. Epub 2019 Feb 22.

PMID:
30796033
3.

Next-generation sequencing in precision oncology: Patient understanding and expectations.

Roberts JS, Gornick MC, Le LQ, Bartnik NJ, Zikmund-Fisher BJ, Chinnaiyan AM; MI-ONCOSEQ Study team.

Cancer Med. 2019 Jan;8(1):227-237. doi: 10.1002/cam4.1947. Epub 2019 Jan 1.

4.

Double-Stranded RNA Sensing Determines Epithelial Cell Identity.

Liao CP, Tchegnon E, Le LQ.

J Invest Dermatol. 2019 Jan;139(1):17-19. doi: 10.1016/j.jid.2018.08.008.

PMID:
30579424
5.
6.

NF1 heterozygosity fosters de novo tumorigenesis but impairs malignant transformation.

Brosseau JP, Liao CP, Wang Y, Ramani V, Vandergriff T, Lee M, Patel A, Ariizumi K, Le LQ.

Nat Commun. 2018 Nov 27;9(1):5014. doi: 10.1038/s41467-018-07452-y.

7.

Spatiotemporal Loss of NF1 in Schwann Cell Lineage Leads to Different Types of Cutaneous Neurofibroma Susceptible to Modification by the Hippo Pathway.

Chen Z, Mo J, Brosseau JP, Shipman T, Wang Y, Liao CP, Cooper JM, Allaway RJ, Gosline SJC, Guinney J, Carroll TJ, Le LQ.

Cancer Discov. 2019 Jan;9(1):114-129. doi: 10.1158/2159-8290.CD-18-0151. Epub 2018 Oct 22.

PMID:
30348677
8.

The biology of cutaneous neurofibromas: Consensus recommendations for setting research priorities.

Brosseau JP, Pichard DC, Legius EH, Wolkenstein P, Lavker RM, Blakeley JO, Riccardi VM, Verma SK, Brownell I, Le LQ.

Neurology. 2018 Jul 10;91(2 Supplement 1):S14-S20. doi: 10.1212/WNL.0000000000005788.

PMID:
29987131
9.

Creating a comprehensive research strategy for cutaneous neurofibromas.

Blakeley JO, Wolkenstein P, Widemann BC, Lee J, Le LQ, Jackson R, Stathis M, Verma SK.

Neurology. 2018 Jul 10;91(2 Supplement 1):S1-S4. doi: 10.1212/WNL.0000000000005789.

PMID:
29987129
10.

Cutaneous neurofibromas in the genomics era: current understanding and open questions.

Allaway RJ, Gosline SJC, La Rosa S, Knight P, Bakker A, Guinney J, Le LQ.

Br J Cancer. 2018 Jun;118(12):1539-1548. doi: 10.1038/s41416-018-0073-2. Epub 2018 Apr 26. Review.

11.

2016 Children's Tumor Foundation conference on neurofibromatosis type 1, neurofibromatosis type 2, and schwannomatosis.

Fisher MJ, Belzberg AJ, de Blank P, De Raedt T, Elefteriou F, Ferner RE, Giovannini M, Harris GJ, Kalamarides M, Karajannis MA, Kim A, Lázaro C, Le LQ, Li W, Listernick R, Martin S, Morrison H, Pasmant E, Ratner N, Schorry E, Ullrich NJ, Viskochil D, Weiss B, Widemann BC, Zhu Y, Bakker A, Serra E.

Am J Med Genet A. 2018 May;176(5):1258-1269. doi: 10.1002/ajmg.a.38675.

12.

Contributions of inflammation and tumor microenvironment to neurofibroma tumorigenesis.

Liao CP, Booker RC, Brosseau JP, Chen Z, Mo J, Tchegnon E, Wang Y, Clapp DW, Le LQ.

J Clin Invest. 2018 Jul 2;128(7):2848-2861. doi: 10.1172/JCI99424. Epub 2018 May 21.

13.

Arsenical keratosis secondary to Fowler solution.

Hinojosa JA, Williams CL, Vandergriff T, Le LQ.

JAAD Case Rep. 2017 Dec 19;4(1):72-74. doi: 10.1016/j.jdcr.2017.11.008. eCollection 2018 Jan. No abstract available.

14.

Clinical Value of Multiparametric Whole-Body Magnetic Resonance Imaging over Whole-Spine Magnetic Resonance Imaging in Patients with Neurofibromatosis Type I.

Zhang L, Dessouky R, Xi Y, Chhabra A, Le LQ.

World Neurosurg. 2017 Dec;108:729-737. doi: 10.1016/j.wneu.2017.09.066. Epub 2017 Sep 20.

PMID:
28939538
15.

Updated nomenclature for human and mouse neurofibromatosis type 1 genes.

Anastasaki C, Le LQ, Kesterson RA, Gutmann DH.

Neurol Genet. 2017 Jul 26;3(4):e169. doi: 10.1212/NXG.0000000000000169. eCollection 2017 Aug. No abstract available.

16.

Identification of hair shaft progenitors that create a niche for hair pigmentation.

Liao CP, Booker RC, Morrison SJ, Le LQ.

Genes Dev. 2017 Apr 15;31(8):744-756. doi: 10.1101/gad.298703.117. Epub 2017 May 2.

17.

Tumor segmentation of whole-body magnetic resonance imaging in neurofibromatosis type 1 patients: tumor burden correlates.

Heffler MA, Le LQ, Xi Y, Chhabra A.

Skeletal Radiol. 2017 Jan;46(1):93-99. Epub 2016 Nov 4.

PMID:
27815599
18.

The role of nerve microenvironment for neurofibroma development.

Liao CP, Pradhan S, Chen Z, Patel AJ, Booker RC, Le LQ.

Oncotarget. 2016 Sep 20;7(38):61500-61508. doi: 10.18632/oncotarget.11133.

19.

Steric and Electronic Influence of Aryl Isocyanides on the Properties of Iridium(III) Cyclometalates.

Maity A, Le LQ, Zhu Z, Bao J, Teets TS.

Inorg Chem. 2016 Mar 7;55(5):2299-308. doi: 10.1021/acs.inorgchem.5b02691. Epub 2016 Feb 24.

PMID:
26905022
20.

Cells of origin in the embryonic nerve roots for NF1-associated plexiform neurofibroma.

Chen Z, Liu C, Patel AJ, Liao CP, Wang Y, Le LQ.

Cancer Cell. 2014 Nov 10;26(5):695-706. doi: 10.1016/j.ccell.2014.09.009. Epub 2014 Oct 30.

21.

BET bromodomain inhibition triggers apoptosis of NF1-associated malignant peripheral nerve sheath tumors through Bim induction.

Patel AJ, Liao CP, Chen Z, Liu C, Wang Y, Le LQ.

Cell Rep. 2014 Jan 16;6(1):81-92. doi: 10.1016/j.celrep.2013.12.001. Epub 2013 Dec 27.

22.

Preclinical therapeutic efficacy of a novel pharmacologic inducer of apoptosis in malignant peripheral nerve sheath tumors.

Chau V, Lim SK, Mo W, Liu C, Patel AJ, McKay RM, Wei S, Posner BA, De Brabander JK, Williams NS, Parada LF, Le LQ.

Cancer Res. 2014 Jan 15;74(2):586-97. doi: 10.1158/0008-5472.CAN-13-1934. Epub 2013 Nov 27.

23.

Ontogenic changes in lung cholesterol metabolism, lipid content, and histology in mice with Niemann-Pick type C disease.

Ramirez CM, Lopez AM, Le LQ, Posey KS, Weinberg AG, Turley SD.

Biochim Biophys Acta. 2014 Jan;1841(1):54-61. doi: 10.1016/j.bbalip.2013.09.010. Epub 2013 Sep 26.

24.

CXCR4/CXCL12 mediate autocrine cell- cycle progression in NF1-associated malignant peripheral nerve sheath tumors.

Mo W, Chen J, Patel A, Zhang L, Chau V, Li Y, Cho W, Lim K, Xu J, Lazar AJ, Creighton CJ, Bolshakov S, McKay RM, Lev D, Le LQ, Parada LF.

Cell. 2013 Feb 28;152(5):1077-90. doi: 10.1016/j.cell.2013.01.053. Epub 2013 Feb 21.

25.

Recurrent perianal red plaque with superficial erosions and pustular exudate in a 16-month-old boy.

Hoang MT, Carroll BT, Le LQ.

Clin Exp Dermatol. 2013 Mar;38(2):203-4. doi: 10.1111/j.1365-2230.2011.04283.x. Epub 2012 Oct 1. No abstract available.

PMID:
23020708
26.

Skin-derived precursors as a source of progenitors for cutaneous nerve regeneration.

Chen Z, Pradhan S, Liu C, Le LQ.

Stem Cells. 2012 Oct;30(10):2261-70. doi: 10.1002/stem.1186.

27.

An exophytic, bleeding nodule on the left malar region.

Hoang MT, Mock JR, Hoang MP, Cohen JB, Le LQ.

Clin Exp Dermatol. 2013 Mar;38(2):217-8. doi: 10.1111/j.1365-2230.2012.04400.x. Epub 2012 Jun 8. No abstract available.

PMID:
22681240
28.

Susceptible stages in Schwann cells for NF1-associated plexiform neurofibroma development.

Le LQ, Liu C, Shipman T, Chen Z, Suter U, Parada LF.

Cancer Res. 2011 Jul 1;71(13):4686-95. doi: 10.1158/0008-5472.CAN-10-4577. Epub 2011 May 6.

29.

Treatment of indeterminate cell histiocytosis with pravastatin.

Burns MV, Ahmed A, Callahan GB, Le LQ, Cockerell C.

J Am Acad Dermatol. 2011 May;64(5):e85-6. doi: 10.1016/j.jaad.2010.08.022. No abstract available.

PMID:
21496694
30.

Cutaneous features predict paraspinal neurofibromas in neurofibromatosis type 1.

Brown RM, Klesse LJ, Le LQ.

J Invest Dermatol. 2010 Sep;130(9):2167-9. doi: 10.1038/jid.2010.206.

31.

Yeast profilin complements profilin deficiency in transgenic tomato fruits and allows development of hypoallergenic tomato fruits.

Le LQ, Mahler V, Scheurer S, Foetisch K, Braun Y, Weigand D, Enrique E, Lidholm J, Paulus KE, Sonnewald S, Vieths S, Sonnewald U.

FASEB J. 2010 Dec;24(12):4939-47. doi: 10.1096/fj.10-163063. Epub 2010 Aug 13.

PMID:
20709910
32.

Cell of origin and microenvironment contribution for NF1-associated dermal neurofibromas.

Le LQ, Shipman T, Burns DK, Parada LF.

Cell Stem Cell. 2009 May 8;4(5):453-63. doi: 10.1016/j.stem.2009.03.017.

33.

Genome-wide siRNA-based functional genomics of pigmentation identifies novel genes and pathways that impact melanogenesis in human cells.

Ganesan AK, Ho H, Bodemann B, Petersen S, Aruri J, Koshy S, Richardson Z, Le LQ, Krasieva T, Roth MG, Farmer P, White MA.

PLoS Genet. 2008 Dec;4(12):e1000298. doi: 10.1371/journal.pgen.1000298. Epub 2008 Dec 5.

34.

A case of simultaneously occurring lichen sclerosus and segmental vitiligo: connecting the underlying autoimmune pathogenesis.

Weisberg EL, Le LQ, Cohen JB.

Int J Dermatol. 2008 Oct;47(10):1053-5. doi: 10.1111/j.1365-4632.2008.03623.x. No abstract available.

PMID:
18986354
35.

Tumor microenvironment and neurofibromatosis type I: connecting the GAPs.

Le LQ, Parada LF.

Oncogene. 2007 Jul 12;26(32):4609-16. Epub 2007 Feb 12. Review.

36.

Design of tomato fruits with reduced allergenicity by dsRNAi-mediated inhibition of ns-LTP (Lyc e 3) expression.

Le LQ, Lorenz Y, Scheurer S, Fötisch K, Enrique E, Bartra J, Biemelt S, Vieths S, Sonnewald U.

Plant Biotechnol J. 2006 Mar;4(2):231-42.

37.

Reduced allergenicity of tomato fruits harvested from Lyc e 1-silenced transgenic tomato plants.

Le LQ, Mahler V, Lorenz Y, Scheurer S, Biemelt S, Vieths S, Sonnewald U.

J Allergy Clin Immunol. 2006 Nov;118(5):1176-83. Epub 2006 Sep 8.

PMID:
17088146
38.

Retraction.

Witte ON, Kabarowski JH, Xu Y, Le LQ, Zhu K.

Science. 2005 Jan 14;307(5707):206. No abstract available.

PMID:
15653487
39.

Positron emission tomography imaging analysis of G2A as a negative modifier of lymphoid leukemogenesis initiated by the BCR-ABL oncogene.

Le LQ, Kabarowski JH, Wong S, Nguyen K, Gambhir SS, Witte ON.

Cancer Cell. 2002 May;1(4):381-91.

40.
41.

Mice lacking the orphan G protein-coupled receptor G2A develop a late-onset autoimmune syndrome.

Le LQ, Kabarowski JH, Weng Z, Satterthwaite AB, Harvill ET, Jensen ER, Miller JF, Witte ON.

Immunity. 2001 May;14(5):561-71.

42.

Direct genetic demonstration of G alpha 13 coupling to the orphan G protein-coupled receptor G2A leading to RhoA-dependent actin rearrangement.

Kabarowski JH, Feramisco JD, Le LQ, Gu JL, Luoh SW, Simon MI, Witte ON.

Proc Natl Acad Sci U S A. 2000 Oct 24;97(22):12109-14.

43.

A DNA damage and stress inducible G protein-coupled receptor blocks cells in G2/M.

Weng Z, Fluckiger AC, Nisitani S, Wahl MI, Le LQ, Hunter CA, Fernal AA, Le Beau MM, Witte ON.

Proc Natl Acad Sci U S A. 1998 Oct 13;95(21):12334-9.

44.

Regional gene therapy with a BMP-2-producing murine stromal cell line induces heterotopic and orthotopic bone formation in rodents.

Lieberman JR, Le LQ, Wu L, Finerman GA, Berk A, Witte ON, Stevenson S.

J Orthop Res. 1998 May;16(3):330-9.

PMID:
9671928

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