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Items: 13

1.

A Novel Anti-HER2 Antibody-Drug Conjugate XMT-1522 for HER2-Positive Breast And Gastric Cancers Resistant to Trastuzumab Emtansine.

Le Joncour V, Martins A, Puhka M, Isola J, Salmikangas M, Laakkonen P, Joensuu H, Barok M.

Mol Cancer Ther. 2019 Jul 10. pii: molcanther.0207.2019. doi: 10.1158/1535-7163.MCT-19-0207. [Epub ahead of print]

PMID:
31292166
2.

Vulnerability of invasive glioblastoma cells to lysosomal membrane destabilization.

Le Joncour V, Filppu P, Hyvönen M, Holopainen M, Turunen SP, Sihto H, Burghardt I, Joensuu H, Tynninen O, Jääskeläinen J, Weller M, Lehti K, Käkelä R, Laakkonen P.

EMBO Mol Med. 2019 Jun;11(6). pii: e9034. doi: 10.15252/emmm.201809034.

3.

Octreotide Conjugates for Tumor Targeting and Imaging.

Figueras E, Martins A, Borbély A, Le Joncour V, Cordella P, Perego R, Modena D, Pagani P, Esposito S, Auciello G, Frese M, Gallinari P, Laakkonen P, Steinkühler C, Sewald N.

Pharmaceutics. 2019 May 7;11(5). pii: E220. doi: 10.3390/pharmaceutics11050220.

4.

Predicting In Vivo Payloads Delivery using a Blood-brain Tumor-barrier in a Dish.

Le Joncour V, Karaman S, Laakkonen PM.

J Vis Exp. 2019 Apr 16;(146). doi: 10.3791/59384.

PMID:
31058900
5.

Seek & Destroy, use of targeting peptides for cancer detection and drug delivery.

Le Joncour V, Laakkonen P.

Bioorg Med Chem. 2018 Jun 1;26(10):2797-2806. doi: 10.1016/j.bmc.2017.08.052. Epub 2017 Sep 1. Review.

6.

Selenoprotein T Deficiency Leads to Neurodevelopmental Abnormalities and Hyperactive Behavior in Mice.

Castex MT, Arabo A, Bénard M, Roy V, Le Joncour V, Prévost G, Bonnet JJ, Anouar Y, Falluel-Morel A.

Mol Neurobiol. 2016 Nov;53(9):5818-5832. doi: 10.1007/s12035-015-9505-7. Epub 2015 Oct 26.

PMID:
26497036
7.

Chemotactic G protein-coupled receptors control cell migration by repressing autophagosome biogenesis.

Coly PM, Perzo N, Le Joncour V, Lecointre C, Schouft MT, Desrues L, Tonon MC, Wurtz O, Gandolfo P, Castel H, Morin F.

Autophagy. 2016 Dec;12(12):2344-2362. Epub 2016 Oct 7.

8.

Gene expression analyses of primary melanomas reveal CTHRC1 as an important player in melanoma progression.

Eriksson J, Le Joncour V, Nummela P, Jahkola T, Virolainen S, Laakkonen P, Saksela O, Hölttä E.

Oncotarget. 2016 Mar 22;7(12):15065-92. doi: 10.18632/oncotarget.7604.

9.

Signaling switch of the urotensin II vasosactive peptide GPCR: prototypic chemotaxic mechanism in glioma.

Lecointre C, Desrues L, Joubert JE, Perzo N, Guichet PO, Le Joncour V, Brulé C, Chabbert M, Leduc R, Prézeau L, Laquerrière A, Proust F, Gandolfo P, Morin F, Castel H.

Oncogene. 2015 Sep 24;34(39):5080-94. doi: 10.1038/onc.2014.433. Epub 2015 Jan 19.

PMID:
25597409
10.

Evaluation of the impact of the cancer therapy everolimus on the central nervous system in mice.

Dubois M, Le Joncour V, Tonon MC, Anouar Y, Proust F, Morin F, Gandolfo P, Joly F, Hilber P, Castel H.

PLoS One. 2014 Dec 1;9(12):e113533. doi: 10.1371/journal.pone.0113533. eCollection 2014.

11.

Synthesis, biological evaluation, and in vivo imaging of the first camptothecin-fluorescein conjugate.

Chevalier A, Dubois M, Le Joncour V, Dautrey S, Lecointre C, Romieu A, Renard PY, Castel H, Sabot C.

Bioconjug Chem. 2013 Jul 17;24(7):1119-33. doi: 10.1021/bc3005304. Epub 2013 Jun 24.

PMID:
23750546
12.

Synthesis and biological evaluation of a novel (99m)Tc labeled 2-nitroimidazole derivative as a potential agent for imaging tumor hypoxia.

Joyard Y, Le Joncour V, Castel H, Diouf CB, Bischoff L, Papamicaël C, Levacher V, Vera P, Bohn P.

Bioorg Med Chem Lett. 2013 Jul 1;23(13):3704-8. doi: 10.1016/j.bmcl.2013.05.015. Epub 2013 May 16.

PMID:
23726027
13.

Neuroprotective effects of PACAP against ethanol-induced toxicity in the developing rat cerebellum.

Botia B, Jolivel V, Burel D, Le Joncour V, Roy V, Naassila M, Bénard M, Fournier A, Vaudry H, Vaudry D.

Neurotox Res. 2011 Apr;19(3):423-34. doi: 10.1007/s12640-010-9186-y. Epub 2010 Apr 27.

PMID:
20422475

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