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Items: 38

1.

FZD5 is a Gαq-coupled receptor that exhibits the functional hallmarks of prototypical GPCRs.

Wright SC, Cañizal MCA, Benkel T, Simon K, Le Gouill C, Matricon P, Namkung Y, Lukasheva V, König GM, Laporte SA, Carlsson J, Kostenis E, Bouvier M, Schulte G, Hoffmann C.

Sci Signal. 2018 Dec 4;11(559). pii: eaar5536. doi: 10.1126/scisignal.aar5536.

PMID:
30514810
2.

Type 2 diabetes-associated variants of the MT2 melatonin receptor affect distinct modes of signaling.

Karamitri A, Plouffe B, Bonnefond A, Chen M, Gallion J, Guillaume JL, Hegron A, Boissel M, Canouil M, Langenberg C, Wareham NJ, Le Gouill C, Lukasheva V, Lichtarge O, Froguel P, Bouvier M, Jockers R.

Sci Signal. 2018 Aug 28;11(545). pii: eaan6622. doi: 10.1126/scisignal.aan6622.

PMID:
30154102
3.

Evolutionary action and structural basis of the allosteric switch controlling β2AR functional selectivity.

Schönegge AM, Gallion J, Picard LP, Wilkins AD, Le Gouill C, Audet M, Stallaert W, Lohse MJ, Kimmel M, Lichtarge O, Bouvier M.

Nat Commun. 2017 Dec 18;8(1):2169. doi: 10.1038/s41467-017-02257-x.

4.

Mapping GPR88-Venus illuminates a novel role for GPR88 in sensory processing.

Ehrlich AT, Semache M, Bailly J, Wojcik S, Arefin TM, Colley C, Le Gouill C, Gross F, Lukasheva V, Hogue M, Darcq E, Harsan LA, Bouvier M, Kieffer BL.

Brain Struct Funct. 2018 Apr;223(3):1275-1296. doi: 10.1007/s00429-017-1547-3. Epub 2017 Nov 6.

PMID:
29110094
5.

Purinergic Receptor Transactivation by the β2-Adrenergic Receptor Increases Intracellular Ca2+ in Nonexcitable Cells.

Stallaert W, van der Westhuizen ET, Schönegge AM, Plouffe B, Hogue M, Lukashova V, Inoue A, Ishida S, Aoki J, Le Gouill C, Bouvier M.

Mol Pharmacol. 2017 May;91(5):533-544. doi: 10.1124/mol.116.106419. Epub 2017 Mar 9.

6.

Monitoring G protein-coupled receptor and β-arrestin trafficking in live cells using enhanced bystander BRET.

Namkung Y, Le Gouill C, Lukashova V, Kobayashi H, Hogue M, Khoury E, Song M, Bouvier M, Laporte SA.

Nat Commun. 2016 Jul 11;7:12178. doi: 10.1038/ncomms12178.

7.

Cellular and subcellular context determine outputs from signaling biosensors.

Devost D, Audet N, Zhou C, Kobayashi H, Bonin H, Lukashova V, Le Gouill C, Bouvier M, Hébert TE.

Methods Cell Biol. 2016;132:319-37. doi: 10.1016/bs.mcb.2015.11.010. Epub 2016 Jan 29.

PMID:
26928550
8.

Quantifying biased signaling in GPCRs using BRET-based biosensors.

Namkung Y, Radresa O, Armando S, Devost D, Beautrait A, Le Gouill C, Laporte SA.

Methods. 2016 Jan 1;92:5-10. doi: 10.1016/j.ymeth.2015.04.010. Epub 2015 Apr 15.

PMID:
25890247
9.

Multiplexing of multicolor bioluminescence resonance energy transfer.

Breton B, Sauvageau É, Zhou J, Bonin H, Le Gouill C, Bouvier M.

Biophys J. 2010 Dec 15;99(12):4037-46. doi: 10.1016/j.bpj.2010.10.025.

10.

Pharmacological chaperones restore function to MC4R mutants responsible for severe early-onset obesity.

René P, Le Gouill C, Pogozheva ID, Lee G, Mosberg HI, Farooqi IS, Valenzano KJ, Bouvier M.

J Pharmacol Exp Ther. 2010 Dec;335(3):520-32. doi: 10.1124/jpet.110.172098. Epub 2010 Sep 8.

11.

A novel biased allosteric compound inhibitor of parturition selectively impedes the prostaglandin F2alpha-mediated Rho/ROCK signaling pathway.

Goupil E, Tassy D, Bourguet C, Quiniou C, Wisehart V, Pétrin D, Le Gouill C, Devost D, Zingg HH, Bouvier M, Saragovi HU, Chemtob S, Lubell WD, Claing A, Hébert TE, Laporte SA.

J Biol Chem. 2010 Aug 13;285(33):25624-36. doi: 10.1074/jbc.M110.115196. Epub 2010 Jun 15.

12.

Caveolae facilitate but are not essential for platelet-activating factor-mediated calcium mobilization and extracellular signal-regulated kinase activation.

Poisson C, Rollin S, Véronneau S, Bousquet SM, Larrivée JF, Le Gouill C, Boulay G, Stankova J, Rola-Pleszczynski M.

J Immunol. 2009 Aug 15;183(4):2747-57. doi: 10.4049/jimmunol.0802651. Epub 2009 Jul 20.

13.

Functional selectivity of natural and synthetic prostaglandin EP4 receptor ligands.

Leduc M, Breton B, Galés C, Le Gouill C, Bouvier M, Chemtob S, Heveker N.

J Pharmacol Exp Ther. 2009 Oct;331(1):297-307. doi: 10.1124/jpet.109.156398. Epub 2009 Jul 7.

14.

Inverse agonist-induced signaling and down-regulation of the platelet-activating factor receptor.

Dupré DJ, Thompson C, Chen Z, Rollin S, Larrivée JF, Le Gouill C, Rola-Pleszczynski M, Stanková J.

Cell Signal. 2007 Oct;19(10):2068-79. Epub 2007 Jun 13.

PMID:
17609120
15.

Agonist-induced internalization of leukotriene B(4) receptor 1 requires G-protein-coupled receptor kinase 2 but not arrestins.

Chen Z, Gaudreau R, Le Gouill C, Rola-Pleszczynski M, Stanková J.

Mol Pharmacol. 2004 Sep;66(3):377-86.

16.

Inverse agonist activity of selected ligands of the cysteinyl-leukotriene receptor 1.

Dupré DJ, Le Gouill C, Gingras D, Rola-Pleszczynski M, Stanková J.

J Pharmacol Exp Ther. 2004 Apr;309(1):102-8. Epub 2004 Jan 12.

17.

Structural determinants regulating expression of the high affinity leukotriene B4 receptor: involvement of dileucine motifs and alpha-helix VIII.

Gaudreau R, Beaulieu ME, Chen Z, Le Gouill C, Lavigne P, Stanková J, Rola-Pleszczynski M.

J Biol Chem. 2004 Mar 12;279(11):10338-45. Epub 2003 Dec 19.

18.

Trafficking, ubiquitination, and down-regulation of the human platelet-activating factor receptor.

Dupré DJ, Chen Z, Le Gouill C, Thériault C, Parent JL, Rola-Pleszczynski M, Stankova J.

J Biol Chem. 2003 Nov 28;278(48):48228-35. Epub 2003 Sep 18.

19.

Upregulation of expression of the chemokine receptor CCR5 by hydrogen peroxide in human monocytes.

Lehoux G, Le Gouill C, Stankova J, Rola-Pleszczynski M.

Mediators Inflamm. 2003 Feb;12(1):29-35.

20.

An expanded V2 receptor retention signal.

Le Gouill C, Innamorati G, Birnbaumer M.

FEBS Lett. 2002 Dec 18;532(3):363-6.

21.

GIP, a G-protein-coupled receptor interacting protein.

Innamorati G, Whang MI, Molteni R, Le Gouill C, Birnbaumer M.

Regul Pept. 2002 Nov 15;109(1-3):173-9.

PMID:
12409230
22.
23.
24.

Inverse agonist activity of selected ligands of platelet-activating factor receptor.

Dupré DJ, Le Gouill C, Rola-Pleszczynski M, Stanková J.

J Pharmacol Exp Ther. 2001 Oct;299(1):358-65.

25.

The long and the short cycle. Alternative intracellular routes for trafficking of G-protein-coupled receptors.

Innamorati G, Le Gouill C, Balamotis M, Birnbaumer M.

J Biol Chem. 2001 Apr 20;276(16):13096-103. Epub 2001 Jan 9.

26.

IL-10 up-regulates CCR5 gene expression in human monocytes.

Houle M, Thivierge M, Le Gouill C, Stankovà J, Rola-Pleszczynski M.

Inflammation. 1999 Jun;23(3):241-51.

PMID:
10392758
27.

Selective modulation of wild type receptor functions by mutants of G-protein-coupled receptors.

Le Gouill C, Parent JL, Caron CA, Gaudreau R, Volkov L, Rola-Pleszczynski M, Stanková J.

J Biol Chem. 1999 Apr 30;274(18):12548-54.

28.

Signalling through the leukotriene B4 receptor involves both alphai and alpha16, but not alphaq or alpha11 G-protein subunits.

Gaudreau R, Le Gouill C, Métaoui S, Lemire S, Stankovà J, Rola-Pleszczynski M.

Biochem J. 1998 Oct 1;335 ( Pt 1):15-8.

30.

Structural and functional requirements for agonist-induced internalization of the human platelet-activating factor receptor.

Le Gouill C, Parent JL, Rola-Pleszczynski M, Stanková J.

J Biol Chem. 1997 Aug 22;272(34):21289-95.

31.

Role of the Cys90, Cys95 and Cys173 residues in the structure and function of the human platelet-activating factor receptor.

Le Gouill C, Parent JL, Rola-Pleszczynski M, Stanková J.

FEBS Lett. 1997 Feb 3;402(2-3):203-8.

32.

Mutations of two adjacent amino acids generate inactive and constitutively active forms of the human platelet-activating factor receptor.

Parent JL, Le Gouill C, de Brum-Fernandes AJ, Rola-Pleszczynski M, Stanková J.

J Biol Chem. 1996 Apr 5;271(14):7949-55.

33.
34.

A highly efficient technique for cloning of refractory DNA fragments and polymerase chain reaction products.

Parent JL, Le Gouill C, Rola-Pleszczynski M, Stanková J.

Anal Biochem. 1994 Aug 1;220(2):426-8. No abstract available.

PMID:
7978289
35.

Analysis of recombinant plasmids by a modified alkaline lysis method.

Le Gouill C, Parent JL, Rola-Pleszczynski M, Stankova J.

Anal Biochem. 1994 May 15;219(1):164. No abstract available.

PMID:
8059948
37.

Construction of a shuttle lacZ alpha-based Escherichia coli-actinomycetes vector containing the phage JHJ-3 replicon.

Gaudreau LR, Le Gouill C, Déry CV.

FEMS Microbiol Lett. 1992 Dec 1;78(2-3):257-60.

PMID:
1490607
38.

A rapid procedure for the screening of recombinant plasmids.

Le Gouill C, Déry CV.

Nucleic Acids Res. 1991 Dec 11;19(23):6655. No abstract available.

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