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Items: 12

1.

Dual blockade of IL-4 and IL-13 with dupilumab, an IL-4Rα antibody, is required to broadly inhibit type 2 inflammation.

Le Floc'h A, Allinne J, Nagashima K, Scott G, Birchard D, Asrat S, Bai Y, Lim WK, Martin J, Huang T, Potocky TB, Kim JH, Rafique A, Papadopoulos NJ, Stahl N, Yancopoulos GD, Murphy AJ, Sleeman MA, Orengo JM.

Allergy. 2019 Dec 14. doi: 10.1111/all.14151. [Epub ahead of print]

PMID:
31838750
2.

Correction: Annular PIP3 accumulation controls actin architecture and modulates cytotoxicity at the immunological synapse.

Le Floc'h A, Tanaka Y, Bantilan NS, Voisinne G, Altan-Bonnet G, Fukui Y, Huse M.

J Exp Med. 2017 Apr 3;214(4):1203. doi: 10.1084/jem.2013132403102017c. Epub 2017 Mar 14. No abstract available.

3.

Cytotoxic T Cells Use Mechanical Force to Potentiate Target Cell Killing.

Basu R, Whitlock BM, Husson J, Le Floc'h A, Jin W, Oyler-Yaniv A, Dotiwala F, Giannone G, Hivroz C, Biais N, Lieberman J, Kam LC, Huse M.

Cell. 2016 Mar 24;165(1):100-110. doi: 10.1016/j.cell.2016.01.021. Epub 2016 Feb 25.

4.

Molecular mechanisms and functional implications of polarized actin remodeling at the T cell immunological synapse.

Le Floc'h A, Huse M.

Cell Mol Life Sci. 2015 Feb;72(3):537-556. doi: 10.1007/s00018-014-1760-7. Epub 2014 Oct 30. Review.

5.

Diacylglycerol kinase α establishes T cell polarity by shaping diacylglycerol accumulation at the immunological synapse.

Chauveau A, Le Floc'h A, Bantilan NS, Koretzky GA, Huse M.

Sci Signal. 2014 Aug 26;7(340):ra82. doi: 10.1126/scisignal.2005287.

6.

Annular PIP3 accumulation controls actin architecture and modulates cytotoxicity at the immunological synapse.

Le Floc'h A, Tanaka Y, Bantilan NS, Voisinne G, Altan-Bonnet G, Fukui Y, Huse M.

J Exp Med. 2013 Nov 18;210(12):2721-37. doi: 10.1084/jem.20131324. Epub 2013 Nov 4. Erratum in: J Exp Med. 2017 Apr 3;214(4):1203.

7.

From lipid second messengers to molecular motors: microtubule-organizing center reorientation in T cells.

Huse M, Le Floc'h A, Liu X.

Immunol Rev. 2013 Nov;256(1):95-106. doi: 10.1111/imr.12116. Review.

8.

IL-2-dependent tuning of NK cell sensitivity for target cells is controlled by regulatory T cells.

Gasteiger G, Hemmers S, Firth MA, Le Floc'h A, Huse M, Sun JC, Rudensky AY.

J Exp Med. 2013 Jun 3;210(6):1167-78. doi: 10.1084/jem.20122462. Epub 2013 May 6.

9.

CD103 or LFA-1 engagement at the immune synapse between cytotoxic T cells and tumor cells promotes maturation and regulates T-cell effector functions.

Franciszkiewicz K, Le Floc'h A, Boutet M, Vergnon I, Schmitt A, Mami-Chouaib F.

Cancer Res. 2013 Jan 15;73(2):617-28. doi: 10.1158/0008-5472.CAN-12-2569. Epub 2012 Nov 27.

10.

Minimal engagement of CD103 on cytotoxic T lymphocytes with an E-cadherin-Fc molecule triggers lytic granule polarization via a phospholipase Cgamma-dependent pathway.

Le Floc'h A, Jalil A, Franciszkiewicz K, Validire P, Vergnon I, Mami-Chouaib F.

Cancer Res. 2011 Jan 15;71(2):328-38. doi: 10.1158/0008-5472.CAN-10-2457. Epub 2011 Jan 11.

11.

Intratumoral induction of CD103 triggers tumor-specific CTL function and CCR5-dependent T-cell retention.

Franciszkiewicz K, Le Floc'h A, Jalil A, Vigant F, Robert T, Vergnon I, Mackiewicz A, Benihoud K, Validire P, Chouaib S, Combadière C, Mami-Chouaib F.

Cancer Res. 2009 Aug 1;69(15):6249-55. doi: 10.1158/0008-5472.CAN-08-3571. Epub 2009 Jul 28.

12.

Alpha E beta 7 integrin interaction with E-cadherin promotes antitumor CTL activity by triggering lytic granule polarization and exocytosis.

Le Floc'h A, Jalil A, Vergnon I, Le Maux Chansac B, Lazar V, Bismuth G, Chouaib S, Mami-Chouaib F.

J Exp Med. 2007 Mar 19;204(3):559-70. Epub 2007 Feb 26.

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