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Items: 12

1.

Mouse Parthenogenetic Embryonic Stem Cells with Biparental-Like Expression of Imprinted Genes Generate Cortical-Like Neurons That Integrate into the Injured Adult Cerebral Cortex.

Varrault A, Eckardt S, Girard B, Le Digarcher A, Sassetti I, Meusnier C, Ripoll C, Badalyan A, Bertaso F, McLaughlin KJ, Journot L, Bouschet T.

Stem Cells. 2018 Feb;36(2):192-205. doi: 10.1002/stem.2721. Epub 2017 Nov 10.

2.

Identification of Plagl1/Zac1 binding sites and target genes establishes its role in the regulation of extracellular matrix genes and the imprinted gene network.

Varrault A, Dantec C, Le Digarcher A, Chotard L, Bilanges B, Parrinello H, Dubois E, Rialle S, Severac D, Bouschet T, Journot L.

Nucleic Acids Res. 2017 Oct 13;45(18):10466-10480. doi: 10.1093/nar/gkx672.

3.

In Vitro Corticogenesis from Embryonic Stem Cells Recapitulates the In Vivo Epigenetic Control of Imprinted Gene Expression.

Bouschet T, Dubois E, Reynès C, Kota SK, Rialle S, Maupetit-Méhouas S, Pezet M, Le Digarcher A, Nidelet S, Demolombe V, Cavelier P, Meusnier C, Maurizy C, Sabatier R, Feil R, Arnaud P, Journot L, Varrault A.

Cereb Cortex. 2017 Mar 1;27(3):2418-2433. doi: 10.1093/cercor/bhw102.

PMID:
27095822
4.

A systems-level approach to parental genomic imprinting: the imprinted gene network includes extracellular matrix genes and regulates cell cycle exit and differentiation.

Al Adhami H, Evano B, Le Digarcher A, Gueydan C, Dubois E, Parrinello H, Dantec C, Bouschet T, Varrault A, Journot L.

Genome Res. 2015 Mar;25(3):353-67. doi: 10.1101/gr.175919.114. Epub 2015 Jan 22.

5.

Expression at the imprinted dlk1-gtl2 locus is regulated by proneural genes in the developing telencephalon.

Seibt J, Armant O, Le Digarcher A, Castro D, Ramesh V, Journot L, Guillemot F, Vanderhaeghen P, Bouschet T.

PLoS One. 2012;7(11):e48675. doi: 10.1371/journal.pone.0048675. Epub 2012 Nov 6.

6.

Genome-wide profiling of G protein-coupled receptors in cerebellar granule neurons using high-throughput, real-time PCR.

Maurel B, Le Digarcher A, Dantec C, Journot L.

BMC Genomics. 2011 May 16;12:241. doi: 10.1186/1471-2164-12-241.

7.

Modulation of imprinted gene network in placenta results in normal development of in vitro manipulated mouse embryos.

Fauque P, Ripoche MA, Tost J, Journot L, Gabory A, Busato F, Le Digarcher A, Mondon F, Gut I, Jouannet P, Vaiman D, Dandolo L, Jammes H.

Hum Mol Genet. 2010 May 1;19(9):1779-90. doi: 10.1093/hmg/ddq059. Epub 2010 Feb 11.

PMID:
20150233
8.

H19 acts as a trans regulator of the imprinted gene network controlling growth in mice.

Gabory A, Ripoche MA, Le Digarcher A, Watrin F, Ziyyat A, Forné T, Jammes H, Ainscough JF, Surani MA, Journot L, Dandolo L.

Development. 2009 Oct;136(20):3413-21. doi: 10.1242/dev.036061. Epub 2009 Sep 17.

9.

Identification of potential pharmacological targets by analysis of the comprehensive G protein-coupled receptor repertoire in the four cardiac chambers.

Moore-Morris T, Varrault A, Mangoni ME, Le Digarcher A, Negre V, Dantec C, Journot L, Nargeot J, Couette B.

Mol Pharmacol. 2009 May;75(5):1108-16. doi: 10.1124/mol.108.054155. Epub 2009 Feb 19.

PMID:
19229040
10.

Zac1 regulates an imprinted gene network critically involved in the control of embryonic growth.

Varrault A, Gueydan C, Delalbre A, Bellmann A, Houssami S, Aknin C, Severac D, Chotard L, Kahli M, Le Digarcher A, Pavlidis P, Journot L.

Dev Cell. 2006 Nov;11(5):711-22.

11.

The candidate tumor suppressor gene ZAC is involved in keratinocyte differentiation and its expression is lost in basal cell carcinomas.

Basyuk E, Coulon V, Le Digarcher A, Coisy-Quivy M, Moles JP, Gandarillas A, Journot L.

Mol Cancer Res. 2005 Sep;3(9):483-92.

12.

Genes regulated in neurons undergoing transcription-dependent apoptosis belong to signaling pathways rather than the apoptotic machinery.

Desagher S, Severac D, Lipkin A, Bernis C, Ritchie W, Le Digarcher A, Journot L.

J Biol Chem. 2005 Feb 18;280(7):5693-702. Epub 2004 Nov 12.

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