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Items: 1 to 50 of 208

1.

A phase 2 study of GVAX colon vaccine with cyclophosphamide and pembrolizumab in patients with mismatch repair proficient advanced colorectal cancer.

Yarchoan M, Huang CY, Zhu Q, Ferguson AK, Durham JN, Anders RA, Thompson ED, Rozich NS, Thomas DL 2nd, Nauroth JM, Rodriguez C, Osipov A, De Jesus-Acosta A, Le DT, Murphy AG, Laheru D, Donehower RC, Jaffee EM, Zheng L, Azad NS.

Cancer Med. 2019 Dec 26. doi: 10.1002/cam4.2763. [Epub ahead of print]

2.

Ultra-deep massively parallel sequencing with unique molecular identifier tagging achieves comparable performance to droplet digital PCR for detection and quantification of circulating tumor DNA from lung cancer patients.

Tran LS, Pham HT, Tran VU, Tran TT, Dang AH, Le DT, Nguyen SL, Nguyen NV, Nguyen TV, Vo BT, Dao HT, Nguyen NH, Tran TH, Nguyen CV, Pham PC, Dang-Mai AT, Dinh-Nguyen TK, Phan VH, Do TT, Truong Dinh K, Do HN, Phan MD, Giang H, Nguyen HN.

PLoS One. 2019 Dec 16;14(12):e0226193. doi: 10.1371/journal.pone.0226193. eCollection 2019.

3.

Adeno-associated virus capsid protein expression in Escherichia coli and chemically defined capsid assembly.

Le DT, Radukic MT, Müller KM.

Sci Rep. 2019 Dec 9;9(1):18631. doi: 10.1038/s41598-019-54928-y.

4.

Real-world Treatment Patterns and Clinical Outcomes Across Lines of Therapy in Patients With Advanced/Metastatic Gastric or Gastroesophageal Junction Cancer.

Le DT, Ott PA, Korytowsky B, Le H, Le TK, Zhang Y, Maglinte GA, Abraham P, Patel D, Shangguan T, Chau I.

Clin Colorectal Cancer. 2019 Sep 24. pii: S1533-0028(19)30445-1. doi: 10.1016/j.clcc.2019.09.001. [Epub ahead of print]

5.

The Usefulness of Meta-Analyses to Hip and Knee Surgeons.

Park KJ, Lambert BS, Brown LD, Le DT, Chaliki K, Lee J, Rossano A, Benjamin K, Moreno MR, Incavo SJ.

J Bone Joint Surg Am. 2019 Dec 4;101(23):2082-2090. doi: 10.2106/JBJS.19.00420.

PMID:
31800421
6.

On-line Smoothing and Error Modelling for Integration of GNSS and Visual Odometry.

Duong TT, Chiang KW, Le DT.

Sensors (Basel). 2019 Nov 29;19(23). pii: E5259. doi: 10.3390/s19235259.

7.

Inactivation of human norovirus and its surrogate by the disinfectant consisting of calcium hydrogen carbonate mesoscopic crystals.

Shimakura H, Gen-Nagata F, Haritani M, Furusaki K, Kato Y, Yamashita-Kawanishi N, LE DT, Tsuzuki M, Tohya Y, Kyuwa S, Saito H, Horimoto T, Onodera T, Haga T.

FEMS Microbiol Lett. 2019 Oct 1;366(19). pii: fnz235. doi: 10.1093/femsle/fnz235.

PMID:
31758686
8.

Phase II Open-Label Study of Pembrolizumab in Treatment-Refractory, Microsatellite Instability-High/Mismatch Repair-Deficient Metastatic Colorectal Cancer: KEYNOTE-164.

Le DT, Kim TW, Van Cutsem E, Geva R, Jäger D, Hara H, Burge M, O'Neil B, Kavan P, Yoshino T, Guimbaud R, Taniguchi H, Elez E, Al-Batran SE, Boland PM, Crocenzi T, Atreya CE, Cui Y, Dai T, Marinello P, Diaz LA Jr, André T.

J Clin Oncol. 2020 Jan 1;38(1):11-19. doi: 10.1200/JCO.19.02107. Epub 2019 Nov 14.

PMID:
31725351
9.

Efficacy of Pembrolizumab in Patients With Noncolorectal High Microsatellite Instability/Mismatch Repair-Deficient Cancer: Results From the Phase II KEYNOTE-158 Study.

Marabelle A, Le DT, Ascierto PA, Di Giacomo AM, De Jesus-Acosta A, Delord JP, Geva R, Gottfried M, Penel N, Hansen AR, Piha-Paul SA, Doi T, Gao B, Chung HC, Lopez-Martin J, Bang YJ, Frommer RS, Shah M, Ghori R, Joe AK, Pruitt SK, Diaz LA Jr.

J Clin Oncol. 2020 Jan 1;38(1):1-10. doi: 10.1200/JCO.19.02105. Epub 2019 Nov 4.

PMID:
31682550
10.

Correction to: Developing real-world comparators for clinical trials in chemotherapy-refractory patients with gastric cancer or gastroesophageal junction cancer.

Chau I, Le DT, Ott PA, Korytowsky B, Le H, Le TK, Zhang Y, Sanchez T, Maglinte GA, Laurie M, Abraham P, Patel D, Shangguan T.

Gastric Cancer. 2020 Jan;23(1):142. doi: 10.1007/s10120-019-01021-y.

11.

Lesion-Level Response Dynamics to Programmed Cell Death Protein (PD-1) Blockade.

Osorio JC, Arbour KC, Le DT, Durham JN, Plodkowski AJ, Halpenny DF, Ginsberg MS, Sawan P, Crompton JG, Yu HA, Namakydoust A, Nabet BY, Chaft JE, Riely GJ, Rizvi H, Diaz LA Jr, Hellmann MD.

J Clin Oncol. 2019 Dec 20;37(36):3546-3555. doi: 10.1200/JCO.19.00709. Epub 2019 Nov 1.

PMID:
31675272
12.

Delay-Aware Reverse Approach for Data Aggregation Scheduling in Wireless Sensor Networks.

Nguyen DT, Le DT, Kim M, Choo H.

Sensors (Basel). 2019 Oct 17;19(20). pii: E4511. doi: 10.3390/s19204511.

13.

The Usefulness of Meta-Analyses to Hip and Knee Surgeons.

Park KJ, Lambert BS, Brown LD, Le DT, Chaliki K, Lee J, Rossano A, Benjamin K, Moreno MR, Incavo SJ.

J Bone Joint Surg Am. 2019 Oct 9. doi: 10.2106/JBJS.19.00420. [Epub ahead of print]

PMID:
31596805
14.

Developing real-world comparators for clinical trials in chemotherapy-refractory patients with gastric cancer or gastroesophageal junction cancer.

Chau I, Le DT, Ott PA, Korytowsky B, Le H, Le TK, Zhang Y, Sanchez T, Maglinte GA, Laurie M, Abraham P, Patel D, Shangguan T.

Gastric Cancer. 2020 Jan;23(1):133-141. doi: 10.1007/s10120-019-01008-9. Epub 2019 Sep 23. Erratum in: Gastric Cancer. 2019 Nov 3;:.

15.

AuNP-M2e + sCpG vaccination of juvenile mice generates lifelong protective immunity to influenza A virus infection.

Bimler L, Song AY, Le DT, Murphy Schafer A, Paust S.

Immun Ageing. 2019 Sep 2;16:23. doi: 10.1186/s12979-019-0162-y. eCollection 2019.

16.

Noninvasive Detection of Microsatellite Instability and High Tumor Mutation Burden in Cancer Patients Treated with PD-1 Blockade.

Georgiadis A, Durham JN, Keefer LA, Bartlett BR, Zielonka M, Murphy D, White JR, Lu S, Verner EL, Ruan F, Riley D, Anders RA, Gedvilaite E, Angiuoli S, Jones S, Velculescu VE, Le DT, Diaz LA Jr, Sausen M.

Clin Cancer Res. 2019 Dec 1;25(23):7024-7034. doi: 10.1158/1078-0432.CCR-19-1372. Epub 2019 Sep 10.

PMID:
31506389
17.

Examining the link between thoracic rotation and scapular dyskinesis and shoulder pain amongst college swimmers.

Welbeck AN, Amilo NR, Le DT, Killelea CM, Kirsch AN, Zarzour RH, Burgi CR, Sell TC, Faherty MS.

Phys Ther Sport. 2019 Nov;40:78-84. doi: 10.1016/j.ptsp.2019.08.013. Epub 2019 Aug 29.

PMID:
31499399
18.

Immunopathologic Stratification of Colorectal Cancer for Checkpoint Blockade Immunotherapy.

Llosa NJ, Luber B, Siegel N, Awan AH, Oke T, Zhu Q, Bartlett BR, Aulakh LK, Thompson ED, Jaffee EM, Durham JN, Sears CL, Le DT, Diaz LA Jr, Pardoll DM, Wang H, Housseau F, Anders RA.

Cancer Immunol Res. 2019 Oct;7(10):1574-1579. doi: 10.1158/2326-6066.CIR-18-0927. Epub 2019 Aug 22.

PMID:
31439614
19.

The reliability and validity of the social responsiveness scale to measure autism symptomology in Vietnamese children.

Nguyen PH, Ocansey ME, Miller M, Le DTK, Schmidt RJ, Prado EL.

Autism Res. 2019 Nov;12(11):1706-1718. doi: 10.1002/aur.2179. Epub 2019 Jul 29.

PMID:
31355545
20.

Early results of displaced femoral neck fragility fractures treated with supercapsular percutaneous-assisted total hip arthroplasty.

Mitchell RJ, Kay AB, Smith KM, Murphy SB, Le DT.

Arthroplast Today. 2019 Mar 16;5(2):193-196. doi: 10.1016/j.artd.2019.02.003. eCollection 2019 Jun.

21.

Novel GDAP1 Mutation in a Vietnamese Family with Charcot-Marie-Tooth Disease.

Mai PT, Le DT, Nguyen TT, Le Gia HL, Nguyen Le TH, Le M, Do DM.

Biomed Res Int. 2019 Apr 24;2019:7132494. doi: 10.1155/2019/7132494. eCollection 2019.

22.

Results from a Phase IIb, Randomized, Multicenter Study of GVAX Pancreas and CRS-207 Compared with Chemotherapy in Adults with Previously Treated Metastatic Pancreatic Adenocarcinoma (ECLIPSE Study).

Le DT, Picozzi VJ, Ko AH, Wainberg ZA, Kindler H, Wang-Gillam A, Oberstein P, Morse MA, Zeh HJ 3rd, Weekes C, Reid T, Borazanci E, Crocenzi T, LoConte NK, Musher B, Laheru D, Murphy A, Whiting C, Nair N, Enstrom A, Ferber S, Brockstedt DG, Jaffee EM.

Clin Cancer Res. 2019 Sep 15;25(18):5493-5502. doi: 10.1158/1078-0432.CCR-18-2992. Epub 2019 May 24.

PMID:
31126960
23.

Human natural killer cells mediate adaptive immunity to viral antigens.

Nikzad R, Angelo LS, Aviles-Padilla K, Le DT, Singh VK, Bimler L, Vukmanovic-Stejic M, Vendrame E, Ranganath T, Simpson L, Haigwood NL, Blish CA, Akbar AN, Paust S.

Sci Immunol. 2019 May 10;4(35). pii: eaat8116. doi: 10.1126/sciimmunol.aat8116.

24.

Role of the INDETERMINATE DOMAIN Genes in Plants.

Kumar M, Le DT, Hwang S, Seo PJ, Kim HU.

Int J Mol Sci. 2019 May 9;20(9). pii: E2286. doi: 10.3390/ijms20092286. Review.

25.

Intratumoral Adaptive Immunosuppression and Type 17 Immunity in Mismatch Repair Proficient Colorectal Tumors.

Llosa NJ, Luber B, Tam AJ, Smith KN, Siegel N, Awan AH, Fan H, Oke T, Zhang J, Domingue J, Engle EL, Roberts CA, Bartlett BR, Aulakh LK, Thompson ED, Taube JM, Durham JN, Sears CL, Le DT, Diaz LA, Pardoll DM, Wang H, Anders RA, Housseau F.

Clin Cancer Res. 2019 Sep 1;25(17):5250-5259. doi: 10.1158/1078-0432.CCR-19-0114. Epub 2019 May 6.

PMID:
31061070
26.

Genetic diversity of tumors with mismatch repair deficiency influences anti-PD-1 immunotherapy response.

Mandal R, Samstein RM, Lee KW, Havel JJ, Wang H, Krishna C, Sabio EY, Makarov V, Kuo F, Blecua P, Ramaswamy AT, Durham JN, Bartlett B, Ma X, Srivastava R, Middha S, Zehir A, Hechtman JF, Morris LG, Weinhold N, Riaz N, Le DT, Diaz LA Jr, Chan TA.

Science. 2019 May 3;364(6439):485-491. doi: 10.1126/science.aau0447.

27.

An Interscholastic Network To Generate LexA Enhancer Trap Lines in Drosophila.

Kockel L, Griffin C, Ahmed Y, Fidelak L, Rajan A, Gould EP, Haigney M, Ralston B, Tercek RJ, Galligani L, Rao S, Huq L, Bhargava HK, Dooner AC, Lemmerman EG, Malusa RF, Nguyen TH, Chung JS, Gregory SM, Kuwana KM, Regenold JT, Wei A, Ashton J, Dickinson P, Martel K, Cai C, Chen C, Price S, Qiao J, Shepley D, Zhang J, Chalasani M, Nguyen K, Aalto A, Kim B, Tazawa-Goodchild E, Sherwood A, Rahman A, Wu SYC, Lotzkar J, Michaels S, Aristotle H, Clark A, Gasper G, Xiang E, Schlör FL, Lu M, Haering K, Friberg J, Kuwana A, Lee J, Liu A, Norton E, Hamad L, Lee C, Okeremi D, diTullio H, Dumoulin K, Chi SYG, Derossi GS, Horowitch RE, Issa EC, Le DT, Morales BC, Noori A, Shao J, Cho S, Hoang MN, Johnson IM, Lee KC, Lee M, Madamidola EA, Schmitt KE, Byan G, Park T, Chen J, Monovoukas A, Kang MJ, McGowan T, Walewski JJ, Simon B, Zu SJ, Miller GP, Fitzpatrick KB, Lantz N, Fox E, Collette J, Kurtz R, Duncan C, Palmer R, Rotondo C, Janicki E, Chisholm T, Rankin A, Park S, Kim SK.

G3 (Bethesda). 2019 Jul 9;9(7):2097-2106. doi: 10.1534/g3.119.400105.

28.

Child stunting is associated with child, maternal, and environmental factors in Vietnam.

Beal T, Le DT, Trinh TH, Burra DD, Huynh T, Duong TT, Truong TM, Nguyen DS, Nguyen KT, de Haan S, Jones AD.

Matern Child Nutr. 2019 Oct;15(4):e12826. doi: 10.1111/mcn.12826. Epub 2019 May 2.

PMID:
30958643
29.

Correction to: persistent mutant oncogene specific T cells in two patients benefitting from anti-PD-1.

Smith KN, Llosa NJ, Cottrell TR, Siegel N, Fan H, Suri P, Chan HY, Guo H, Oke T, Awan AH, Verde F, Danilova L, Anagnostou V, Tam AJ, Luber BS, Bartlett BR, Aulakh LK, Sidhom JW, Zhu Q, Sears CL, Cope L, Sharfman WH, Thompson ED, Riemer J, Marrone KA, Naidoo J, Velculescu VE, Forde PM, Vogelstein B, Kinzler KW, Papadopoulos N, Durham JN, Wang H, Le DT, Justesen S, Taube JM, Diaz LA Jr, Brahmer JR, Pardoll DM, Anders RA, Housseau F.

J Immunother Cancer. 2019 Mar 6;7(1):63. doi: 10.1186/s40425-019-0547-7.

30.

The Significance of Ascites in Patients With Pancreatic Ductal Adenocarcinoma: A Case-Control Study.

Baretti M, Pulluri B, Tsai HL, Blackford AL, Wolfgang CL, Laheru D, Zheng L, Herman J, Le DT, Narang AK, de Jesus-Acosta A.

Pancreas. 2019 Apr;48(4):585-589. doi: 10.1097/MPA.0000000000001262.

PMID:
30817723
31.

Persistent mutant oncogene specific T cells in two patients benefitting from anti-PD-1.

Smith KN, Llosa NJ, Cottrell TR, Siegel N, Fan H, Suri P, Chan HY, Guo H, Oke T, Awan AH, Verde F, Danilova L, Anagnostou V, Tam AJ, Luber BS, Bartlett BR, Aulakh LK, Sidhom JW, Zhu Q, Sears CL, Cope L, Sharfman WH, Thompson ED, Riemer J, Marrone KA, Naidoo J, Velculescu VE, Forde PM, Vogelstein B, Kinzler KW, Papadopoulos N, Durham JN, Wang H, Le DT, Justesen S, Taube JM, Diaz LA Jr, Brahmer JR, Pardoll DM, Anders RA, Housseau F.

J Immunother Cancer. 2019 Feb 11;7(1):40. doi: 10.1186/s40425-018-0492-x. Erratum in: J Immunother Cancer. 2019 Mar 6;7(1):63.

32.

A Mutation in the Transcription Factor Foxp3 Drives T Helper 2 Effector Function in Regulatory T Cells.

Van Gool F, Nguyen MLT, Mumbach MR, Satpathy AT, Rosenthal WL, Giacometti S, Le DT, Liu W, Brusko TM, Anderson MS, Rudensky AY, Marson A, Chang HY, Bluestone JA.

Immunity. 2019 Feb 19;50(2):362-377.e6. doi: 10.1016/j.immuni.2018.12.016. Epub 2019 Jan 29.

PMID:
30709738
33.

Anticancer activity of gomisin J from Schisandra chinensis fruit.

Jung S, Moon HI, Kim S, Quynh NTN, Yu J, Sandag Z, Le DT, Lee H, Lee H, Lee MS.

Oncol Rep. 2019 Jan;41(1):711-717. doi: 10.3892/or.2018.6850. Epub 2018 Nov 2.

PMID:
30542721
34.

Two new and potentially highly threatened Megophrys Horned frogs (Amphibia: Megophryidae) from Indochina's highest mountains.

Tapley B, Cutajar T, Mahony S, Nguyen CT, Dau VQ, Luong AM, Le DT, Nguyen TT, Nguyen TQ, Portway C, Luong HV, Rowley JJL.

Zootaxa. 2018 Oct 31;4508(3):301-333. doi: 10.11646/zootaxa.4508.3.1.

PMID:
30485981
35.

Inhibitory role of AMP‑activated protein kinase in necroptosis of HCT116 colon cancer cells with p53 null mutation under nutrient starvation.

Le DT, Jung S, Quynh NTN, Sandag Z, Lee BS, Kim S, Lee H, Lee H, Lee MS.

Int J Oncol. 2019 Feb;54(2):702-712. doi: 10.3892/ijo.2018.4634. Epub 2018 Nov 14.

PMID:
30431068
36.

Acridone alkaloids from the rhizomes of Luvunga scandens (Roxb.) Buch. Ham.

Tran NMA, Do THT, Truong LH, Le DT, Phan MN, Pham NKT, Mai DT, Nguyen TP.

Nat Prod Res. 2019 Aug;33(15):2176-2181. doi: 10.1080/14786419.2018.1492577. Epub 2018 Nov 10.

PMID:
30417672
37.

Identification, Structural Characterization and Gene Expression Analysis of Members of the Nuclear Factor-Y Family in Chickpea (Cicer arietinum L.) under Dehydration and Abscisic Acid Treatments.

Chu HD, Nguyen KH, Watanabe Y, Le DT, Pham TLT, Mochida K, Tran LP.

Int J Mol Sci. 2018 Oct 23;19(11). pii: E3290. doi: 10.3390/ijms19113290.

38.

Integrating Immunotherapy Into Colorectal Cancer Care.

Wilt C, Le DT.

Oncology (Williston Park). 2018 Oct 15;32(10):494-8. Review.

39.

DNA repair defects and implications for immunotherapy.

Bever KM, Le DT.

J Clin Invest. 2018 Oct 1;128(10):4236-4242. doi: 10.1172/JCI122010. Epub 2018 Oct 1. Review.

40.

Full genome analysis of bovine papillomavirus type 1 derived from a calf with severe cutaneous multiple papillomatosis.

Shimakura H, Dong J, Zhu W, Chambers JK, Uchida K, Kiriki K, Uematsu M, Goto Y, Yasuda M, Yamashita-Kawanishi N, Tsuzuki M, LE DT, Hatama S, Haga T.

J Vet Med Sci. 2018 Nov 9;80(11):1691-1695. doi: 10.1292/jvms.18-0289. Epub 2018 Sep 12.

41.

CheckMate-032 Study: Efficacy and Safety of Nivolumab and Nivolumab Plus Ipilimumab in Patients With Metastatic Esophagogastric Cancer.

Janjigian YY, Bendell J, Calvo E, Kim JW, Ascierto PA, Sharma P, Ott PA, Peltola K, Jaeger D, Evans J, de Braud F, Chau I, Harbison CT, Dorange C, Tschaika M, Le DT.

J Clin Oncol. 2018 Oct 1;36(28):2836-2844. doi: 10.1200/JCO.2017.76.6212. Epub 2018 Aug 15. Erratum in: J Clin Oncol. 2019 Feb 10;37(5):443.

42.

A Phase I Trial of a Guadecitabine (SGI-110) and Irinotecan in Metastatic Colorectal Cancer Patients Previously Exposed to Irinotecan.

Lee V, Wang J, Zahurak M, Gootjes E, Verheul HM, Parkinson R, Kerner Z, Sharma A, Rosner G, De Jesus-Acosta A, Laheru D, Le DT, Oganesian A, Lilly E, Brown T, Jones P, Baylin S, Ahuja N, Azad N.

Clin Cancer Res. 2018 Dec 15;24(24):6160-6167. doi: 10.1158/1078-0432.CCR-18-0421. Epub 2018 Aug 10.

43.

T cell receptor repertoire features associated with survival in immunotherapy-treated pancreatic ductal adenocarcinoma.

Hopkins AC, Yarchoan M, Durham JN, Yusko EC, Rytlewski JA, Robins HS, Laheru DA, Le DT, Lutz ER, Jaffee EM.

JCI Insight. 2018 Jul 12;3(13). pii: 122092. doi: 10.1172/jci.insight.122092.

44.

A human anti-IL-2 antibody that potentiates regulatory T cells by a structure-based mechanism.

Trotta E, Bessette PH, Silveria SL, Ely LK, Jude KM, Le DT, Holst CR, Coyle A, Potempa M, Lanier LL, Garcia KC, Crellin NK, Rondon IJ, Bluestone JA.

Nat Med. 2018 Jul;24(7):1005-1014. doi: 10.1038/s41591-018-0070-2. Epub 2018 Jun 25.

45.

Controlled Defect Based Ultra Broadband Full-sized Metamaterial Absorber.

Tran MC, Le DH, Pham VH, Do HT, Le DT, Dang HL, Vu DL.

Sci Rep. 2018 Jun 22;8(1):9523. doi: 10.1038/s41598-018-27920-1.

46.

Function of the evolutionarily conserved plant methionine-S-sulfoxide reductase without the catalytic residue.

Le DT, Nguyen KL, Chu HD, Vu NT, Pham TTL, Tran LP.

Protoplasma. 2018 Nov;255(6):1741-1750. doi: 10.1007/s00709-018-1266-5. Epub 2018 May 28.

PMID:
29808313
47.

Immunotherapy in colorectal cancer.

Le DT.

Clin Adv Hematol Oncol. 2018 Jan;16(1):22-24. No abstract available.

PMID:
29741500
48.

A new species of Leptolalax (Anura: Megophryidae) from Son Tra Peninsula, central Vietnam.

Nguyen LT, Poyarkov NAJ, Le DT, Vo BD, Phan HT, Duong TV, Murphy RW, Nguyen SN.

Zootaxa. 2018 Feb 28;4388(1):1-21. doi: 10.11646/zootaxa.4388.1.1.

PMID:
29690461
49.

Anti-cancerous effect of cis-khellactone from Angelica amurensis through the induction of three programmed cell deaths.

Jung S, Moon HI, Lee BS, Kim S, Quynh NTN, Yu J, Le DT, Sandag Z, Lee H, Lee H, Anh NH, Yang Y, Lim JS, Kim KI, Lee MS.

Oncotarget. 2018 Mar 30;9(24):16744-16757. doi: 10.18632/oncotarget.24686. eCollection 2018 Mar 30.

50.

DNA mismatch repair in cancer.

Baretti M, Le DT.

Pharmacol Ther. 2018 Sep;189:45-62. doi: 10.1016/j.pharmthera.2018.04.004. Epub 2018 Apr 15. Review.

PMID:
29669262

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