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AuNP-M2e + sCpG vaccination of juvenile mice generates lifelong protective immunity to influenza A virus infection.

Bimler L, Song AY, Le DT, Murphy Schafer A, Paust S.

Immun Ageing. 2019 Sep 2;16:23. doi: 10.1186/s12979-019-0162-y. eCollection 2019.


Noninvasive Detection of Microsatellite Instability and High Tumor Mutation Burden in Cancer Patients Treated with PD-1 Blockade.

Georgiadis A, Durham JN, Keefer LA, Bartlett BR, Zielonka M, Murphy D, White JR, Lu S, Verner EL, Ruan F, Riley D, Anders RA, Gedvilaite E, Angiuoli S, Jones S, Velculescu VE, Le DT, Diaz LA Jr, Sausen M.

Clin Cancer Res. 2019 Sep 10. doi: 10.1158/1078-0432.CCR-19-1372. [Epub ahead of print]


Examining the link between thoracic rotation and scapular dyskinesis and shoulder pain amongst college swimmers.

Welbeck AN, Amilo NR, Le DT, Killelea CM, Kirsch AN, Zarzour RH, Burgi CR, Sell TC, Faherty MS.

Phys Ther Sport. 2019 Aug 29;40:78-84. doi: 10.1016/j.ptsp.2019.08.013. [Epub ahead of print]


Immunopathologic Stratification of Colorectal Cancer for Checkpoint Blockade Immunotherapy.

Llosa NJ, Luber B, Siegel N, Awan AH, Oke T, Zhu Q, Bartlett BR, Aulakh LK, Thompson ED, Jaffee EM, Durham JN, Sears CL, Le DT, Diaz LA Jr, Pardoll DM, Wang H, Housseau F, Anders RA.

Cancer Immunol Res. 2019 Aug 22. doi: 10.1158/2326-6066.CIR-18-0927. [Epub ahead of print]


The reliability and validity of the social responsiveness scale to measure autism symptomology in Vietnamese children.

Nguyen PH, Ocansey ME, Miller M, Le DTK, Schmidt RJ, Prado EL.

Autism Res. 2019 Jul 29. doi: 10.1002/aur.2179. [Epub ahead of print]


Early results of displaced femoral neck fragility fractures treated with supercapsular percutaneous-assisted total hip arthroplasty.

Mitchell RJ, Kay AB, Smith KM, Murphy SB, Le DT.

Arthroplast Today. 2019 Mar 16;5(2):193-196. doi: 10.1016/j.artd.2019.02.003. eCollection 2019 Jun.


Novel GDAP1 Mutation in a Vietnamese Family with Charcot-Marie-Tooth Disease.

Mai PT, Le DT, Nguyen TT, Le Gia HL, Nguyen Le TH, Le M, Do DM.

Biomed Res Int. 2019 Apr 24;2019:7132494. doi: 10.1155/2019/7132494. eCollection 2019.


Results from a Phase IIb, Randomized, Multicenter Study of GVAX Pancreas and CRS-207 Compared with Chemotherapy in Adults with Previously Treated Metastatic Pancreatic Adenocarcinoma (ECLIPSE Study).

Le DT, Picozzi VJ, Ko AH, Wainberg ZA, Kindler H, Wang-Gillam A, Oberstein P, Morse MA, Zeh HJ 3rd, Weekes C, Reid T, Borazanci E, Crocenzi T, LoConte NK, Musher B, Laheru D, Murphy A, Whiting C, Nair N, Enstrom A, Ferber S, Brockstedt DG, Jaffee EM.

Clin Cancer Res. 2019 Sep 15;25(18):5493-5502. doi: 10.1158/1078-0432.CCR-18-2992. Epub 2019 May 24.


Human natural killer cells mediate adaptive immunity to viral antigens.

Nikzad R, Angelo LS, Aviles-Padilla K, Le DT, Singh VK, Bimler L, Vukmanovic-Stejic M, Vendrame E, Ranganath T, Simpson L, Haigwood NL, Blish CA, Akbar AN, Paust S.

Sci Immunol. 2019 May 10;4(35). pii: eaat8116. doi: 10.1126/sciimmunol.aat8116.


Role of the INDETERMINATE DOMAIN Genes in Plants.

Kumar M, Le DT, Hwang S, Seo PJ, Kim HU.

Int J Mol Sci. 2019 May 9;20(9). pii: E2286. doi: 10.3390/ijms20092286. Review.


Intratumoral Adaptive Immunosuppression and Type 17 Immunity in Mismatch Repair Proficient Colorectal Tumors.

Llosa NJ, Luber B, Tam AJ, Smith KN, Siegel N, Awan AH, Fan H, Oke T, Zhang J, Domingue J, Engle EL, Roberts CA, Bartlett BR, Aulakh LK, Thompson ED, Taube JM, Durham JN, Sears CL, Le DT, Diaz LA, Pardoll DM, Wang H, Anders RA, Housseau F.

Clin Cancer Res. 2019 Sep 1;25(17):5250-5259. doi: 10.1158/1078-0432.CCR-19-0114. Epub 2019 May 6.


Genetic diversity of tumors with mismatch repair deficiency influences anti-PD-1 immunotherapy response.

Mandal R, Samstein RM, Lee KW, Havel JJ, Wang H, Krishna C, Sabio EY, Makarov V, Kuo F, Blecua P, Ramaswamy AT, Durham JN, Bartlett B, Ma X, Srivastava R, Middha S, Zehir A, Hechtman JF, Morris LG, Weinhold N, Riaz N, Le DT, Diaz LA Jr, Chan TA.

Science. 2019 May 3;364(6439):485-491. doi: 10.1126/science.aau0447.


An Interscholastic Network To Generate LexA Enhancer Trap Lines in Drosophila.

Kockel L, Griffin C, Ahmed Y, Fidelak L, Rajan A, Gould EP, Haigney M, Ralston B, Tercek RJ, Galligani L, Rao S, Huq L, Bhargava HK, Dooner AC, Lemmerman EG, Malusa RF, Nguyen TH, Chung JS, Gregory SM, Kuwana KM, Regenold JT, Wei A, Ashton J, Dickinson P, Martel K, Cai C, Chen C, Price S, Qiao J, Shepley D, Zhang J, Chalasani M, Nguyen K, Aalto A, Kim B, Tazawa-Goodchild E, Sherwood A, Rahman A, Wu SYC, Lotzkar J, Michaels S, Aristotle H, Clark A, Gasper G, Xiang E, Schlör FL, Lu M, Haering K, Friberg J, Kuwana A, Lee J, Liu A, Norton E, Hamad L, Lee C, Okeremi D, diTullio H, Dumoulin K, Chi SYG, Derossi GS, Horowitch RE, Issa EC, Le DT, Morales BC, Noori A, Shao J, Cho S, Hoang MN, Johnson IM, Lee KC, Lee M, Madamidola EA, Schmitt KE, Byan G, Park T, Chen J, Monovoukas A, Kang MJ, McGowan T, Walewski JJ, Simon B, Zu SJ, Miller GP, Fitzpatrick KB, Lantz N, Fox E, Collette J, Kurtz R, Duncan C, Palmer R, Rotondo C, Janicki E, Chisholm T, Rankin A, Park S, Kim SK.

G3 (Bethesda). 2019 Jul 9;9(7):2097-2106. doi: 10.1534/g3.119.400105.


Child stunting is associated with child, maternal, and environmental factors in Vietnam.

Beal T, Le DT, Trinh TH, Burra DD, Huynh T, Duong TT, Truong TM, Nguyen DS, Nguyen KT, de Haan S, Jones AD.

Matern Child Nutr. 2019 Apr 8:e12826. doi: 10.1111/mcn.12826. [Epub ahead of print]


Correction to: persistent mutant oncogene specific T cells in two patients benefitting from anti-PD-1.

Smith KN, Llosa NJ, Cottrell TR, Siegel N, Fan H, Suri P, Chan HY, Guo H, Oke T, Awan AH, Verde F, Danilova L, Anagnostou V, Tam AJ, Luber BS, Bartlett BR, Aulakh LK, Sidhom JW, Zhu Q, Sears CL, Cope L, Sharfman WH, Thompson ED, Riemer J, Marrone KA, Naidoo J, Velculescu VE, Forde PM, Vogelstein B, Kinzler KW, Papadopoulos N, Durham JN, Wang H, Le DT, Justesen S, Taube JM, Diaz LA Jr, Brahmer JR, Pardoll DM, Anders RA, Housseau F.

J Immunother Cancer. 2019 Mar 6;7(1):63. doi: 10.1186/s40425-019-0547-7.


The Significance of Ascites in Patients With Pancreatic Ductal Adenocarcinoma: A Case-Control Study.

Baretti M, Pulluri B, Tsai HL, Blackford AL, Wolfgang CL, Laheru D, Zheng L, Herman J, Le DT, Narang AK, de Jesus-Acosta A.

Pancreas. 2019 Apr;48(4):585-589. doi: 10.1097/MPA.0000000000001262.


Persistent mutant oncogene specific T cells in two patients benefitting from anti-PD-1.

Smith KN, Llosa NJ, Cottrell TR, Siegel N, Fan H, Suri P, Chan HY, Guo H, Oke T, Awan AH, Verde F, Danilova L, Anagnostou V, Tam AJ, Luber BS, Bartlett BR, Aulakh LK, Sidhom JW, Zhu Q, Sears CL, Cope L, Sharfman WH, Thompson ED, Riemer J, Marrone KA, Naidoo J, Velculescu VE, Forde PM, Vogelstein B, Kinzler KW, Papadopoulos N, Durham JN, Wang H, Le DT, Justesen S, Taube JM, Diaz LA Jr, Brahmer JR, Pardoll DM, Anders RA, Housseau F.

J Immunother Cancer. 2019 Feb 11;7(1):40. doi: 10.1186/s40425-018-0492-x. Erratum in: J Immunother Cancer. 2019 Mar 6;7(1):63.


A Mutation in the Transcription Factor Foxp3 Drives T Helper 2 Effector Function in Regulatory T Cells.

Van Gool F, Nguyen MLT, Mumbach MR, Satpathy AT, Rosenthal WL, Giacometti S, Le DT, Liu W, Brusko TM, Anderson MS, Rudensky AY, Marson A, Chang HY, Bluestone JA.

Immunity. 2019 Feb 19;50(2):362-377.e6. doi: 10.1016/j.immuni.2018.12.016. Epub 2019 Jan 29.


Anticancer activity of gomisin J from Schisandra chinensis fruit.

Jung S, Moon HI, Kim S, Quynh NTN, Yu J, Sandag Z, Le DT, Lee H, Lee H, Lee MS.

Oncol Rep. 2019 Jan;41(1):711-717. doi: 10.3892/or.2018.6850. Epub 2018 Nov 2.


Two new and potentially highly threatened Megophrys Horned frogs (Amphibia: Megophryidae) from Indochina's highest mountains.

Tapley B, Cutajar T, Mahony S, Nguyen CT, Dau VQ, Luong AM, Le DT, Nguyen TT, Nguyen TQ, Portway C, Luong HV, Rowley JJL.

Zootaxa. 2018 Oct 31;4508(3):301-333. doi: 10.11646/zootaxa.4508.3.1.


Inhibitory role of AMP‑activated protein kinase in necroptosis of HCT116 colon cancer cells with p53 null mutation under nutrient starvation.

Le DT, Jung S, Quynh NTN, Sandag Z, Lee BS, Kim S, Lee H, Lee H, Lee MS.

Int J Oncol. 2019 Feb;54(2):702-712. doi: 10.3892/ijo.2018.4634. Epub 2018 Nov 14.


Acridone alkaloids from the rhizomes of Luvunga scandens (Roxb.) Buch. Ham.

Tran NMA, Do THT, Truong LH, Le DT, Phan MN, Pham NKT, Mai DT, Nguyen TP.

Nat Prod Res. 2019 Aug;33(15):2176-2181. doi: 10.1080/14786419.2018.1492577. Epub 2018 Nov 10.


Identification, Structural Characterization and Gene Expression Analysis of Members of the Nuclear Factor-Y Family in Chickpea (Cicer arietinum L.) under Dehydration and Abscisic Acid Treatments.

Chu HD, Nguyen KH, Watanabe Y, Le DT, Pham TLT, Mochida K, Tran LP.

Int J Mol Sci. 2018 Oct 23;19(11). pii: E3290. doi: 10.3390/ijms19113290.


Integrating Immunotherapy Into Colorectal Cancer Care.

Wilt C, Le DT.

Oncology (Williston Park). 2018 Oct 15;32(10):494-8. Review.


DNA repair defects and implications for immunotherapy.

Bever KM, Le DT.

J Clin Invest. 2018 Oct 1;128(10):4236-4242. doi: 10.1172/JCI122010. Epub 2018 Oct 1. Review.


Full genome analysis of bovine papillomavirus type 1 derived from a calf with severe cutaneous multiple papillomatosis.

Shimakura H, Dong J, Zhu W, Chambers JK, Uchida K, Kiriki K, Uematsu M, Goto Y, Yasuda M, Yamashita-Kawanishi N, Tsuzuki M, LE DT, Hatama S, Haga T.

J Vet Med Sci. 2018 Nov 9;80(11):1691-1695. doi: 10.1292/jvms.18-0289. Epub 2018 Sep 12.


CheckMate-032 Study: Efficacy and Safety of Nivolumab and Nivolumab Plus Ipilimumab in Patients With Metastatic Esophagogastric Cancer.

Janjigian YY, Bendell J, Calvo E, Kim JW, Ascierto PA, Sharma P, Ott PA, Peltola K, Jaeger D, Evans J, de Braud F, Chau I, Harbison CT, Dorange C, Tschaika M, Le DT.

J Clin Oncol. 2018 Oct 1;36(28):2836-2844. doi: 10.1200/JCO.2017.76.6212. Epub 2018 Aug 15. Erratum in: J Clin Oncol. 2019 Feb 10;37(5):443.


A Phase I Trial of a Guadecitabine (SGI-110) and Irinotecan in Metastatic Colorectal Cancer Patients Previously Exposed to Irinotecan.

Lee V, Wang J, Zahurak M, Gootjes E, Verheul HM, Parkinson R, Kerner Z, Sharma A, Rosner G, De Jesus-Acosta A, Laheru D, Le DT, Oganesian A, Lilly E, Brown T, Jones P, Baylin S, Ahuja N, Azad N.

Clin Cancer Res. 2018 Dec 15;24(24):6160-6167. doi: 10.1158/1078-0432.CCR-18-0421. Epub 2018 Aug 10.


T cell receptor repertoire features associated with survival in immunotherapy-treated pancreatic ductal adenocarcinoma.

Hopkins AC, Yarchoan M, Durham JN, Yusko EC, Rytlewski JA, Robins HS, Laheru DA, Le DT, Lutz ER, Jaffee EM.

JCI Insight. 2018 Jul 12;3(13). pii: 122092. doi: 10.1172/jci.insight.122092.


A human anti-IL-2 antibody that potentiates regulatory T cells by a structure-based mechanism.

Trotta E, Bessette PH, Silveria SL, Ely LK, Jude KM, Le DT, Holst CR, Coyle A, Potempa M, Lanier LL, Garcia KC, Crellin NK, Rondon IJ, Bluestone JA.

Nat Med. 2018 Jul;24(7):1005-1014. doi: 10.1038/s41591-018-0070-2. Epub 2018 Jun 25.


Controlled Defect Based Ultra Broadband Full-sized Metamaterial Absorber.

Tran MC, Le DH, Pham VH, Do HT, Le DT, Dang HL, Vu DL.

Sci Rep. 2018 Jun 22;8(1):9523. doi: 10.1038/s41598-018-27920-1.


Function of the evolutionarily conserved plant methionine-S-sulfoxide reductase without the catalytic residue.

Le DT, Nguyen KL, Chu HD, Vu NT, Pham TTL, Tran LP.

Protoplasma. 2018 Nov;255(6):1741-1750. doi: 10.1007/s00709-018-1266-5. Epub 2018 May 28.


Immunotherapy in colorectal cancer.

Le DT.

Clin Adv Hematol Oncol. 2018 Jan;16(1):22-24. No abstract available.


A new species of Leptolalax (Anura: Megophryidae) from Son Tra Peninsula, central Vietnam.

Nguyen LT, Poyarkov NAJ, Le DT, Vo BD, Phan HT, Duong TV, Murphy RW, Nguyen SN.

Zootaxa. 2018 Feb 28;4388(1):1-21. doi: 10.11646/zootaxa.4388.1.1.


Anti-cancerous effect of cis-khellactone from Angelica amurensis through the induction of three programmed cell deaths.

Jung S, Moon HI, Lee BS, Kim S, Quynh NTN, Yu J, Le DT, Sandag Z, Lee H, Lee H, Anh NH, Yang Y, Lim JS, Kim KI, Lee MS.

Oncotarget. 2018 Mar 30;9(24):16744-16757. doi: 10.18632/oncotarget.24686. eCollection 2018 Mar 30.


DNA mismatch repair in cancer.

Baretti M, Le DT.

Pharmacol Ther. 2018 Sep;189:45-62. doi: 10.1016/j.pharmthera.2018.04.004. Epub 2018 Apr 15. Review.


Stereotactic body radiation therapy for palliative management of pancreatic adenocarcinoma in elderly and medically inoperable patients.

Ryan JF, Rosati LM, Groot VP, Le DT, Zheng L, Laheru DA, Shin EJ, Jackson J, Moore J, Narang AK, Herman JM.

Oncotarget. 2018 Mar 27;9(23):16427-16436. doi: 10.18632/oncotarget.24713. eCollection 2018 Mar 27.


Clinical presentation of immune checkpoint inhibitor-induced inflammatory arthritis differs by immunotherapy regimen.

Cappelli LC, Brahmer JR, Forde PM, Le DT, Lipson EJ, Naidoo J, Zheng L, Bingham CO 3rd, Shah AA.

Semin Arthritis Rheum. 2018 Dec;48(3):553-557. doi: 10.1016/j.semarthrit.2018.02.011. Epub 2018 Mar 22.


Histopathological and immunophenotypic features of ipilimumab-associated colitis compared to ulcerative colitis.

Adler BL, Pezhouh MK, Kim A, Luan L, Zhu Q, Gani F, Yarchoan M, Chen J, Voltaggio L, Parian A, Lazarev M, Lauwers GY, Pawlik TM, Montgomery EA, Jaffee E, Le DT, Taube JM, Anders RA.

J Intern Med. 2018 Jun;283(6):568-577. doi: 10.1111/joim.12744. Epub 2018 Mar 24.


Tensile, Thermal, Dielectric and Morphological Properties of Polyoxymethylene/Silica Nanocomposites.

Mai TT, Chinh NT, Baskaran R, Trang NTT, Thang VV, Le DTT, Minh DQ, Hoang T.

J Nanosci Nanotechnol. 2018 Jul 1;18(7):4963-4970. doi: 10.1166/jnn.2018.15352.


Feeling out a link between feeling and infant sociomoral evaluation.

Steckler CM, Liberman Z, Van de Vondervoort JW, Slevinsky J, Le DT, Hamlin JK.

Br J Dev Psychol. 2018 Sep;36(3):482-500. doi: 10.1111/bjdp.12232. Epub 2017 Dec 28.


Field- and clinically derived estimates of Wolbachia-mediated blocking of dengue virus transmission potential in Aedes aegypti mosquitoes.

Carrington LB, Tran BCN, Le NTH, Luong TTH, Nguyen TT, Nguyen PT, Nguyen CVV, Nguyen HTC, Vu TT, Vo LT, Le DT, Vu NT, Nguyen GT, Luu HQ, Dang AD, Hurst TP, O'Neill SL, Tran VT, Kien DTH, Nguyen NM, Wolbers M, Wills B, Simmons CP.

Proc Natl Acad Sci U S A. 2018 Jan 9;115(2):361-366. doi: 10.1073/pnas.1715788115. Epub 2017 Dec 26.


A rare case of esophageal metastasis from pancreatic ductal adenocarcinoma: a case report and literature review.

Rosati LM, Kummerlowe MN, Poling J, Hacker-Prietz A, Narang AK, Shin EJ, Le DT, Fishman EK, Hruban RH, Yang SC, Weiss MJ, Herman JM.

Oncotarget. 2017 Jun 12;8(59):100942-100950. doi: 10.18632/oncotarget.18458. eCollection 2017 Nov 21.


Wound healing activity of Streptocaulon juventas root ethanolic extract.

Nguyen MC, Le DT, Kamei K, Dang TPT.

Wound Repair Regen. 2017 Nov;25(6):956-963. doi: 10.1111/wrr.12599. Epub 2018 Feb 7.


Multiplex Proximity Ligation Assay to Identify Potential Prognostic Biomarkers for Improved Survival in Locally Advanced Pancreatic Cancer Patients Treated With Stereotactic Body Radiation Therapy.

Rao AD, Liu Y, von Eyben R, Hsu CC, Hu C, Rosati LM, Parekh A, Ng K, Hacker-Prietz A, Zheng L, Pawlik TM, Laheru DA, Jaffee EM, Weiss MJ, Le DT, Hruban RH, De Jesus-Acosta A, Wolfgang CL, Narang AK, Chang DT, Koong AC, Herman JM.

Int J Radiat Oncol Biol Phys. 2018 Feb 1;100(2):486-489. doi: 10.1016/j.ijrobp.2017.10.001. Epub 2017 Oct 12.


Stereotactic Body Radiation Therapy for Isolated Local Recurrence After Surgical Resection of Pancreatic Ductal Adenocarcinoma Appears to be Safe and Effective.

Ryan JF, Groot VP, Rosati LM, Hacker-Prietz A, Narang AK, McNutt TR, Jackson JF, Le DT, Jaffee EM, Zheng L, Laheru DA, He J, Pawlik TM, Weiss MJ, Wolfgang CL, Herman JM.

Ann Surg Oncol. 2018 Jan;25(1):280-289. doi: 10.1245/s10434-017-6134-6. Epub 2017 Oct 23.


A Blueprint to Advance Colorectal Cancer Immunotherapies.

Le DT, Hubbard-Lucey VM, Morse MA, Heery CR, Dwyer A, Marsilje TH, Brodsky AN, Chan E, Deming DA, Diaz LA Jr, Fridman WH, Goldberg RM, Hamilton SR, Housseau F, Jaffee EM, Kang SP, Krishnamurthi SS, Lieu CH, Messersmith W, Sears CL, Segal NH, Yang A, Moss RA, Cha E, O'Donnell-Tormey J, Roach N, Davis AQ, McAbee K, Worrall S, Benson AB.

Cancer Immunol Res. 2017 Nov;5(11):942-949. doi: 10.1158/2326-6066.CIR-17-0375. Epub 2017 Oct 16.


Potential transmission opportunity of CTX-M-producing Escherichia coli on a large-scale chicken farm in Vietnam.

Bui TKN, Bui TMH, Ueda S, Le DT, Yamamoto Y, Hirai I.

J Glob Antimicrob Resist. 2018 Jun;13:1-6. doi: 10.1016/j.jgar.2017.09.014. Epub 2017 Oct 10.


Cutaneous Eruptions in Patients Receiving Immune Checkpoint Blockade: Clinicopathologic Analysis of the Nonlichenoid Histologic Pattern.

Kaunitz GJ, Loss M, Rizvi H, Ravi S, Cuda JD, Bleich KB, Esandrio J, Sander I, Le DT, Diaz LA Jr, Brahmer JR, Drake CG, Hollmann TJ, Lacouture ME, Hellmann MD, Lipson EJ, Taube JM.

Am J Surg Pathol. 2017 Oct;41(10):1381-1389. doi: 10.1097/PAS.0000000000000900.


Social evaluation of intentional, truly accidental, and negligently accidental helpers and harmers by 10-month-old infants.

Woo BM, Steckler CM, Le DT, Hamlin JK.

Cognition. 2017 Nov;168:154-163. doi: 10.1016/j.cognition.2017.06.029. Epub 2017 Jul 5.


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