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Items: 1 to 50 of 70

1.

TE1PA as Innovating Chelator for 64Cu Immuno-TEP Imaging: A Comparative in Vivo Study with DOTA/NOTA by Conjugation on 9E7.4 mAb in a Syngeneic Multiple Myeloma Model.

Navarro AS, Le Bihan T, Le Saëc P, Bris NL, Bailly C, Saï-Maurel C, Bourgeois M, Chérel M, Tripier R, Faivre-Chauvet A.

Bioconjug Chem. 2019 Sep 18;30(9):2393-2403. doi: 10.1021/acs.bioconjchem.9b00510. Epub 2019 Aug 22.

PMID:
31386357
2.

A role for S-nitrosylation of the SUMO-conjugating enzyme SCE1 in plant immunity.

Skelly MJ, Malik SI, Le Bihan T, Bo Y, Jiang J, Spoel SH, Loake GJ.

Proc Natl Acad Sci U S A. 2019 Aug 20;116(34):17090-17095. doi: 10.1073/pnas.1900052116. Epub 2019 Aug 1.

PMID:
31371496
3.

Shotgun proteomic analysis of nanoparticle-synthesizing Desulfovibrio alaskensis in response to platinum and palladium.

Capeness MJ, Imrie L, Mühlbauer LF, Le Bihan T, Horsfall LE.

Microbiology. 2019 Jul 30. doi: 10.1099/mic.0.000840. [Epub ahead of print]

PMID:
31361216
4.

Genome annotation improvements from cross-phyla proteogenomics and time-of-day differences in malaria mosquito proteins using untargeted quantitative proteomics.

Imrie L, Le Bihan T, O'Toole Á, Hickner PV, Dunn WA, Weise B, Rund SSC.

PLoS One. 2019 Jul 29;14(7):e0220225. doi: 10.1371/journal.pone.0220225. eCollection 2019.

5.

Quantitative Phosphoproteomic Using Titanium Dioxide Micro-Columns and Label-Free Quantitation.

Barrios-Llerena ME, Le Bihan T.

Methods Mol Biol. 2019;1977:35-42. doi: 10.1007/978-1-4939-9232-4_4.

PMID:
30980321
6.

Time-resolved interaction proteomics of the GIGANTEA protein under diurnal cycles in Arabidopsis.

Krahmer J, Goralogia GS, Kubota A, Zardilis A, Johnson RS, Song YH, MacCoss MJ, Le Bihan T, Halliday KJ, Imaizumi T, Millar AJ.

FEBS Lett. 2019 Feb;593(3):319-338. doi: 10.1002/1873-3468.13311. Epub 2018 Dec 28.

7.

Redox regulation of pyruvate kinase M2 by cysteine oxidation and S-nitrosation.

Mitchell AR, Yuan M, Morgan HP, McNae IW, Blackburn EA, Le Bihan T, Homem RA, Yu M, Loake GJ, Michels PA, Wear MA, Walkinshaw MD.

Biochem J. 2018 Oct 31;475(20):3275-3291. doi: 10.1042/BCJ20180556.

8.

Synthesis of C-functionalized TE1PA and comparison with its analogues. An example of bioconjugation on 9E7.4 mAb for multiple myeloma 64Cu-PET imaging.

Le Bihan T, Navarro AS, Le Bris N, Le Saëc P, Gouard S, Haddad F, Gestin JF, Chérel M, Faivre-Chauvet A, Tripier R.

Org Biomol Chem. 2018 Jun 13;16(23):4261-4271. doi: 10.1039/c8ob00499d.

PMID:
29701218
9.

Sumoylation of the Plant Clock Transcription Factor CCA1 Suppresses DNA Binding.

Hansen LL, Imrie L, Le Bihan T, van den Burg HA, van Ooijen G.

J Biol Rhythms. 2017 Dec;32(6):570-582. doi: 10.1177/0748730417737695. Epub 2017 Nov 27.

10.

A structurally distinct TGF-β mimic from an intestinal helminth parasite potently induces regulatory T cells.

Johnston CJC, Smyth DJ, Kodali RB, White MPJ, Harcus Y, Filbey KJ, Hewitson JP, Hinck CS, Ivens A, Kemter AM, Kildemoes AO, Le Bihan T, Soares DC, Anderton SM, Brenn T, Wigmore SJ, Woodcock HV, Chambers RC, Hinck AP, McSorley HJ, Maizels RM.

Nat Commun. 2017 Nov 23;8(1):1741. doi: 10.1038/s41467-017-01886-6.

11.

Glycogen Synthase Kinase-3 Modulates Cbl-b and Constrains T Cell Activation.

Tran CW, Saibil SD, Le Bihan T, Hamilton SR, Lang KS, You H, Lin AE, Garza KM, Elford AR, Tai K, Parsons ME, Wigmore K, Vainberg MG, Penninger JM, Woodgett JR, Mak TW, Ohashi PS.

J Immunol. 2017 Dec 15;199(12):4056-4065. doi: 10.4049/jimmunol.1600396. Epub 2017 Nov 6.

12.

HpARI Protein Secreted by a Helminth Parasite Suppresses Interleukin-33.

Osbourn M, Soares DC, Vacca F, Cohen ES, Scott IC, Gregory WF, Smyth DJ, Toivakka M, Kemter AM, le Bihan T, Wear M, Hoving D, Filbey KJ, Hewitson JP, Henderson H, Gonzàlez-Cìscar A, Errington C, Vermeren S, Astier AL, Wallace WA, Schwarze J, Ivens AC, Maizels RM, McSorley HJ.

Immunity. 2017 Oct 17;47(4):739-751.e5. doi: 10.1016/j.immuni.2017.09.015.

13.

Nucleoredoxin guards against oxidative stress by protecting antioxidant enzymes.

Kneeshaw S, Keyani R, Delorme-Hinoux V, Imrie L, Loake GJ, Le Bihan T, Reichheld JP, Spoel SH.

Proc Natl Acad Sci U S A. 2017 Jul 19. pii: 201703344. doi: 10.1073/pnas.1703344114. [Epub ahead of print]

14.

Protein Co-Expression Analysis as a Strategy to Complement a Standard Quantitative Proteomics Approach: Case of a Glioblastoma Multiforme Study.

Kanonidis EI, Roy MM, Deighton RF, Le Bihan T.

PLoS One. 2016 Aug 29;11(8):e0161828. doi: 10.1371/journal.pone.0161828. eCollection 2016.

15.

Erratum to: Fibrinogen production is enhanced in an in-vitro model of non-alcoholic fatty liver disease: an isolated risk factor for cardiovascular events?

Yeung EN, Treskes P, Martin SF, Manning JR, Dunbar DR, Rogers SM, Le Bihan T, Lockman KA, Morley SD, Hayes PC, Nelson LJ, Plevris JN.

Lipids Health Dis. 2016 Aug 1;15(1):125. No abstract available.

16.

Proteomic profiling of cellular steatosis with concomitant oxidative stress in vitro.

Lockman KA, Htun V, Sinha R, Treskes P, Nelson LJ, Martin SF, Rogers SM, Le Bihan T, Hayes PC, Plevris JN.

Lipids Health Dis. 2016 Jul 2;15:114. doi: 10.1186/s12944-016-0283-7.

17.

Data from quantitative label free proteomics analysis of rat spleen.

Dudekula K, Le Bihan T.

Data Brief. 2016 Jun 4;8:494-500. doi: 10.1016/j.dib.2016.05.058. eCollection 2016 Sep.

18.

Identification of S-Nitrosothiols by the Sequential Cysteine Blocking Technique.

Homem RA, Le Bihan T, Yu M, Loake GJ.

Methods Mol Biol. 2016;1424:163-74. doi: 10.1007/978-1-4939-3600-7_14.

PMID:
27094419
19.

Identification of novel pathways linking epithelial-to-mesenchymal transition with resistance to HER2-targeted therapy.

Creedon H, Gómez-Cuadrado L, Tarnauskaitė Ž, Balla J, Canel M, MacLeod KG, Serrels B, Fraser C, Unciti-Broceta A, Tracey N, Le Bihan T, Klinowska T, Sims AH, Byron A, Brunton VG.

Oncotarget. 2016 Mar 8;7(10):11539-52. doi: 10.18632/oncotarget.7317.

20.

Erratum: Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity.

Buck AH, Coakley G, Simbari F, McSorley HJ, Quintana JF, Le Bihan T, Kumar S, Abreu-Goodger C, Lear M, Harcus Y, Ceroni A, Babayan SA, Blaxter M, Ivens A, Maizels RM.

Nat Commun. 2015 Oct 22;6:8772. doi: 10.1038/ncomms9772. No abstract available.

21.

Cell populations can use aneuploidy to survive telomerase insufficiency.

Millet C, Ausiannikava D, Le Bihan T, Granneman S, Makovets S.

Nat Commun. 2015 Oct 22;6:8664. doi: 10.1038/ncomms9664.

22.

Rock geochemistry induces stress and starvation responses in the bacterial proteome.

Bryce CC, Le Bihan T, Martin SF, Harrison JP, Bush T, Spears B, Moore A, Leys N, Byloos B, Cockell CS.

Environ Microbiol. 2016 Apr;18(4):1110-21. doi: 10.1111/1462-2920.13093. Epub 2015 Dec 22.

PMID:
26470852
23.

Fibrinogen production is enhanced in an in-vitro model of non-alcoholic fatty liver disease: an isolated risk factor for cardiovascular events?

Yeung EN, Treskes P, Martin SF, Manning JR, Dunbar DR, Rogers SM, Le Bihan T, Lockman KA, Morley SD, Hayes PC, Nelson LJ, Plevris JN.

Lipids Health Dis. 2015 Aug 10;14:86. doi: 10.1186/s12944-015-0069-3. Erratum in: Lipids Health Dis. 2016;15(1):125.

24.

Label-free quantitative analysis of the casein kinase 2-responsive phosphoproteome of the marine minimal model species Ostreococcus tauri.

Le Bihan T, Hindle M, Martin SF, Barrios-Llerena ME, Krahmer J, Kis K, Millar AJ, van Ooijen G.

Proteomics. 2015 Dec;15(23-24):4135-44. doi: 10.1002/pmic.201500086. Epub 2015 Jun 9.

25.

Sample preparation for phosphoproteomic analysis of circadian time series in Arabidopsis thaliana.

Krahmer J, Hindle MM, Martin SF, Le Bihan T, Millar AJ.

Methods Enzymol. 2015;551:405-31. doi: 10.1016/bs.mie.2014.10.022. Epub 2014 Dec 26.

26.

Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity.

Buck AH, Coakley G, Simbari F, McSorley HJ, Quintana JF, Le Bihan T, Kumar S, Abreu-Goodger C, Lear M, Harcus Y, Ceroni A, Babayan SA, Blaxter M, Ivens A, Maizels RM.

Nat Commun. 2014 Nov 25;5:5488. doi: 10.1038/ncomms6488. Erratum in: Nat Commun. 2015;6:8772.

27.

Snapshots of pre-rRNA structural flexibility reveal eukaryotic 40S assembly dynamics at nucleotide resolution.

Hector RD, Burlacu E, Aitken S, Le Bihan T, Tuijtel M, Zaplatina A, Cook AG, Granneman S.

Nucleic Acids Res. 2014 Oct 29;42(19):12138-54. doi: 10.1093/nar/gku815. Epub 2014 Sep 8.

28.

The reduced kinome of Ostreococcus tauri: core eukaryotic signalling components in a tractable model species.

Hindle MM, Martin SF, Noordally ZB, van Ooijen G, Barrios-Llerena ME, Simpson TI, Le Bihan T, Millar AJ.

BMC Genomics. 2014 Aug 2;15:640. doi: 10.1186/1471-2164-15-640.

29.

CPF-associated phosphatase activity opposes condensin-mediated chromosome condensation.

Vanoosthuyse V, Legros P, van der Sar SJ, Yvert G, Toda K, Le Bihan T, Watanabe Y, Hardwick K, Bernard P.

PLoS Genet. 2014 Jun 19;10(6):e1004415. doi: 10.1371/journal.pgen.1004415. eCollection 2014 Jun.

30.

The proteomic response in glioblastoma in young patients.

Deighton RF, Le Bihan T, Martin SF, Barrios-Llerena ME, Gerth AM, Kerr LE, McCulloch J, Whittle IR.

J Neurooncol. 2014 Aug;119(1):79-89. doi: 10.1007/s11060-014-1474-6. Epub 2014 May 18.

31.

Interactions among mitochondrial proteins altered in glioblastoma.

Deighton RF, Le Bihan T, Martin SF, Gerth AMJ, McCulloch M, Edgar JM, Kerr LE, Whittle IR, McCulloch J.

J Neurooncol. 2014 Jun;118(2):247-256. doi: 10.1007/s11060-014-1430-5. Epub 2014 Apr 13.

32.

Impact of age on the cerebrovascular proteomes of wild-type and Tg-SwDI mice.

Searcy JL, Le Bihan T, Salvadores N, McCulloch J, Horsburgh K.

PLoS One. 2014 Feb 26;9(2):e89970. doi: 10.1371/journal.pone.0089970. eCollection 2014.

33.

PI3K/Akt1 signalling specifies foregut precursors by generating regionalized extra-cellular matrix.

Villegas SN, Rothová M, Barrios-Llerena ME, Pulina M, Hadjantonakis AK, Le Bihan T, Astrof S, Brickman JM.

Elife. 2013 Dec 24;2:e00806. doi: 10.7554/eLife.00806.

34.

Functional analysis of the rodent CK1tau mutation in the circadian clock of a marine unicellular alga.

van Ooijen G, Martin SF, Barrios-Llerena ME, Hindle M, Le Bihan T, O'Neill JS, Millar AJ.

BMC Cell Biol. 2013 Oct 15;14:46. doi: 10.1186/1471-2121-14-46.

35.

Total variance should drive data handling strategies in third generation proteomic studies.

Herrmann AG, Searcy JL, Le Bihan T, McCulloch J, Deighton RF.

Proteomics. 2013 Nov;13(22):3251-5. doi: 10.1002/pmic.201300056. Epub 2013 Oct 27.

36.

Functional analysis of Casein Kinase 1 in a minimal circadian system.

van Ooijen G, Hindle M, Martin SF, Barrios-Llerena M, Sanchez F, Bouget FY, O'Neill JS, Le Bihan T, Millar AJ.

PLoS One. 2013 Jul 25;8(7):e70021. doi: 10.1371/journal.pone.0070021. Print 2013.

37.

Telomeres, a busy platform for cell signaling.

Gardano L, Pucci F, Christian L, Le Bihan T, Harrington L.

Front Oncol. 2013 Jun 10;3:146. doi: 10.3389/fonc.2013.00146. eCollection 2013.

38.

Photobacterium profundum under pressure: a MS-based label-free quantitative proteomics study.

Le Bihan T, Rayner J, Roy MM, Spagnolo L.

PLoS One. 2013 May 31;8(5):e60897. doi: 10.1371/journal.pone.0060897. Print 2013.

39.

Adaptive changes in the neuronal proteome: mitochondrial energy production, endoplasmic reticulum stress, and ribosomal dysfunction in the cellular response to metabolic stress.

Herrmann AG, Deighton RF, Le Bihan T, McCulloch MC, Searcy JL, Kerr LE, McCulloch J.

J Cereb Blood Flow Metab. 2013 May;33(5):673-83. doi: 10.1038/jcbfm.2012.204. Epub 2013 Jan 16.

40.

Native gel electrophoresis of human telomerase distinguishes active complexes with or without dyskerin.

Gardano L, Holland L, Oulton R, Le Bihan T, Harrington L.

Nucleic Acids Res. 2012 Mar;40(5):e36. doi: 10.1093/nar/gkr1243. Epub 2011 Dec 19.

41.

Proteome turnover in the green alga Ostreococcus tauri by time course 15N metabolic labeling mass spectrometry.

Martin SF, Munagapati VS, Salvo-Chirnside E, Kerr LE, Le Bihan T.

J Proteome Res. 2012 Jan 1;11(1):476-86. doi: 10.1021/pr2009302. Epub 2011 Dec 1.

PMID:
22077659
42.

S-nitrosylation of NADPH oxidase regulates cell death in plant immunity.

Yun BW, Feechan A, Yin M, Saidi NB, Le Bihan T, Yu M, Moore JW, Kang JG, Kwon E, Spoel SH, Pallas JA, Loake GJ.

Nature. 2011 Oct 13;478(7368):264-8. doi: 10.1038/nature10427.

PMID:
21964330
43.

Proteomic analysis of mitochondria in APOE transgenic mice and in response to an ischemic challenge.

James R, Searcy JL, Le Bihan T, Martin SF, Gliddon CM, Povey J, Deighton RF, Kerr LE, McCulloch J, Horsburgh K.

J Cereb Blood Flow Metab. 2012 Jan;32(1):164-76. doi: 10.1038/jcbfm.2011.120. Epub 2011 Aug 31. Erratum in: J Cereb Blood Flow Metab. 2012 Feb;32(2):399.

44.

The use of a novel quantitation strategy based on Reductive Isotopic Di-Ethylation (RIDE) to evaluate the effect of glufosinate on the unicellular algae Ostreococcus tauri.

Barrios-Llerena ME, Pritchard JC, Kerr LE, Le Bihan T.

J Proteomics. 2011 Nov 18;74(12):2798-809. doi: 10.1016/j.jprot.2011.06.014. Epub 2011 Jun 25.

PMID:
21726673
45.

Shotgun proteomic analysis of the unicellular alga Ostreococcus tauri.

Le Bihan T, Martin SF, Chirnside ES, van Ooijen G, Barrios-Llerena ME, O'Neill JS, Shliaha PV, Kerr LE, Millar AJ.

J Proteomics. 2011 Sep 6;74(10):2060-70. doi: 10.1016/j.jprot.2011.05.028. Epub 2011 May 24.

PMID:
21635980
46.

Circadian clock parameter measurement: characterization of clock transcription factors using surface plasmon resonance.

O'Neill JS, van Ooijen G, Le Bihan T, Millar AJ.

J Biol Rhythms. 2011 Apr;26(2):91-8. doi: 10.1177/0748730410397465.

47.

SCFCdc4 enables mating type switching in yeast by cyclin-dependent kinase-mediated elimination of the Ash1 transcriptional repressor.

Liu Q, Larsen B, Ricicova M, Orlicky S, Tekotte H, Tang X, Craig K, Quiring A, Le Bihan T, Hansen C, Sicheri F, Tyers M.

Mol Cell Biol. 2011 Feb;31(3):584-98. doi: 10.1128/MCB.00845-10. Epub 2010 Nov 22.

48.
49.

Symmetry breaking of ionic semiconductors under pressure: the case of InAs.

Libotte H, Aquilanti G, Pascarelli S, Crichton WA, Le Bihan T, Gaspard JP.

J Phys Condens Matter. 2009 Dec 2;21(49):495801. doi: 10.1088/0953-8984/21/49/495801. Epub 2009 Nov 13.

PMID:
21836204
50.

Gel free analysis of the proteome of intracellular Leishmania mexicana.

Paape D, Barrios-Llerena ME, Le Bihan T, Mackay L, Aebischer T.

Mol Biochem Parasitol. 2010 Feb;169(2):108-14. doi: 10.1016/j.molbiopara.2009.10.009. Epub 2009 Nov 10.

PMID:
19900490

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