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Items: 24


Neuromedin U is a gut peptide that alters oral glucose tolerance by delaying gastric emptying via direct contraction of the pylorus and vagal-dependent mechanisms.

Jarry AC, Merah N, Cisse F, Cayetanot F, Fiamma MN, Willemetz A, Gueddouri D, Barka B, Valet P, Guilmeau S, Bado A, Le Beyec J, Bodineau L, Le Gall M.

FASEB J. 2019 Apr;33(4):5377-5388. doi: 10.1096/fj.201801718R. Epub 2019 Feb 12.


Intestinal plasticity in response to nutrition and gastrointestinal surgery.

Le Gall M, Thenet S, Aguanno D, Jarry AC, Genser L, Ribeiro-Parenti L, Joly F, Ledoux S, Bado A, Le Beyec J.

Nutr Rev. 2019 Mar 1;77(3):129-143. doi: 10.1093/nutrit/nuy064.


Fasting levels of glicentin are higher in Roux-en-Y gastric bypass patients exhibiting postprandial hypoglycemia during a meal test.

Poitou C, Bouaziz-Amar E, Genser L, Oppert JM, Lacorte JM, Le Beyec J.

Surg Obes Relat Dis. 2018 Jul;14(7):929-935. doi: 10.1016/j.soard.2018.03.014. Epub 2018 Mar 19.


Evaluation of a melanocortin-4 receptor (MC4R) agonist (Setmelanotide) in MC4R deficiency.

Collet TH, Dubern B, Mokrosinski J, Connors H, Keogh JM, Mendes de Oliveira E, Henning E, Poitou-Bernert C, Oppert JM, Tounian P, Marchelli F, Alili R, Le Beyec J, Pépin D, Lacorte JM, Gottesdiener A, Bounds R, Sharma S, Folster C, Henderson B, O'Rahilly S, Stoner E, Gottesdiener K, Panaro BL, Cone RD, Clément K, Farooqi IS, Van der Ploeg LHT.

Mol Metab. 2017 Oct;6(10):1321-1329. doi: 10.1016/j.molmet.2017.06.015. Epub 2017 Jul 8.


Microbiota Is Involved in Post-resection Adaptation in Humans with Short Bowel Syndrome.

Gillard L, Mayeur C, Robert V, Pingenot I, Le Beyec J, Bado A, Lepage P, Thomas M, Joly F.

Front Physiol. 2017 Apr 19;8:224. doi: 10.3389/fphys.2017.00224. eCollection 2017.


Extensive Intestinal Resection Triggers Behavioral Adaptation, Intestinal Remodeling and Microbiota Transition in Short Bowel Syndrome.

Mayeur C, Gillard L, Le Beyec J, Bado A, Joly F, Thomas M.

Microorganisms. 2016 Mar 8;4(1). pii: E16. doi: 10.3390/microorganisms4010016. Review.


Enhanced Ghrelin Levels and Hypothalamic Orexigenic AgRP and NPY Neuropeptide Expression in Models of Jejuno-Colonic Short Bowel Syndrome.

Gillard L, Billiauws L, Stan-Iuga B, Ribeiro-Parenti L, Jarry AC, Cavin JB, Cluzeaud F, Mayeur C, Thomas M, Freund JN, Lacorte JM, Le Gall M, Bado A, Joly F, Le Beyec J.

Sci Rep. 2016 Jun 21;6:28345. doi: 10.1038/srep28345.


Remodeling of the residual gastric mucosa after roux-en-y gastric bypass or vertical sleeve gastrectomy in diet-induced obese rats.

Arapis K, Cavin JB, Gillard L, Cluzeaud F, Lettéron P, Ducroc R, Le Beyec J, Hourseau M, Couvelard A, Marmuse JP, Le Gall M, Bado A.

PLoS One. 2015 Mar 30;10(3):e0121414. doi: 10.1371/journal.pone.0121414. eCollection 2015.


Seven novel deleterious LEPR mutations found in early-onset obesity: a ΔExon6-8 shared by subjects from Reunion Island, France, suggests a founder effect.

Huvenne H, Le Beyec J, Pépin D, Alili R, Kherchiche PP, Jeannic E, Frelut ML, Lacorte JM, Nicolino M, Viard A, Laville M, Ledoux S, Tounian P, Poitou C, Dubern B, Clément K.

J Clin Endocrinol Metab. 2015 May;100(5):E757-66. doi: 10.1210/jc.2015-1036. Epub 2015 Mar 9.


Intestinal deletion of leptin signaling alters activity of nutrient transporters and delayed the onset of obesity in mice.

Tavernier A, Cavin JB, Le Gall M, Ducroc R, Denis RG, Cluzeaud F, Guilmeau S, Sakar Y, Barbot L, Kapel N, Le Beyec J, Joly F, Chua S, Luquet S, Bado A.

FASEB J. 2014 Sep;28(9):4100-10. doi: 10.1096/fj.14-255158. Epub 2014 Jun 13.


Overexpression of gastric leptin precedes adipocyte leptin during high-fat diet and is linked to 5HT-containing enterochromaffin cells.

Le Beyec J, Pelletier AL, Arapis K, Hourseau M, Cluzeaud F, Descatoire V, Ducroc R, Aparicio T, Joly F, Couvelard A, Marmuse JP, Le Gall M, Bado A.

Int J Obes (Lond). 2014 Oct;38(10):1357-64. doi: 10.1038/ijo.2014.14. Epub 2014 Jan 28.


Association between melanocortin-4 receptor mutations and eating behaviors in obese patients: a case--control study.

Valette M, Poitou C, Kesse-Guyot E, Bellisle F, Carette C, Le Beyec J, Hercberg S, Clément K, Czernichow S.

Int J Obes (Lond). 2014 Jun;38(6):883-5. doi: 10.1038/ijo.2013.190. Epub 2013 Oct 9.


Homozygous leptin receptor mutation due to uniparental disomy of chromosome 1: response to bariatric surgery.

Le Beyec J, Cugnet-Anceau C, Pépin D, Alili R, Cotillard A, Lacorte JM, Basdevant A, Laville M, Clément K.

J Clin Endocrinol Metab. 2013 Feb;98(2):E397-402. doi: 10.1210/jc.2012-2779. Epub 2012 Dec 28.


Melanocortin-4 receptor mutations and polymorphisms do not affect weight loss after bariatric surgery.

Valette M, Poitou C, Le Beyec J, Bouillot JL, Clement K, Czernichow S.

PLoS One. 2012;7(11):e48221. doi: 10.1371/journal.pone.0048221. Epub 2012 Nov 21.


Hepatocyte nuclear factor 4alpha, a key factor for homeostasis, cell architecture, and barrier function of the adult intestinal epithelium.

Cattin AL, Le Beyec J, Barreau F, Saint-Just S, Houllier A, Gonzalez FJ, Robine S, Pinçon-Raymond M, Cardot P, Lacasa M, Ribeiro A.

Mol Cell Biol. 2009 Dec;29(23):6294-308. doi: 10.1128/MCB.00939-09. Epub 2009 Oct 5.


Epidermal growth factor receptor is involved in enterocyte anoikis through the dismantling of E-cadherin-mediated junctions.

Lugo-Martínez VH, Petit CS, Fouquet S, Le Beyec J, Chambaz J, Pinçon-Raymond M, Cardot P, Thenet S.

Am J Physiol Gastrointest Liver Physiol. 2009 Feb;296(2):G235-44. doi: 10.1152/ajpgi.90313.2008. Epub 2008 Dec 4.


Cell shape regulates global histone acetylation in human mammary epithelial cells.

Le Beyec J, Xu R, Lee SY, Nelson CM, Rizki A, Alcaraz J, Bissell MJ.

Exp Cell Res. 2007 Aug 15;313(14):3066-75. Epub 2007 Apr 27.


Homozygous null mutation of the melanocortin-4 receptor and severe early-onset obesity.

Dubern B, Bisbis S, Talbaoui H, Le Beyec J, Tounian P, Lacorte JM, Clément K.

J Pediatr. 2007 Jun;150(6):613-7, 617.e1.


E-cadherin-dependent transcriptional control of apolipoprotein A-IV gene expression in intestinal epithelial cells: a role for the hepatic nuclear factor 4.

Peignon G, Thenet S, Schreider C, Fouquet S, Ribeiro A, Dussaulx E, Chambaz J, Cardot P, Pinçon-Raymond M, Le Beyec J.

J Biol Chem. 2006 Feb 10;281(6):3560-8. Epub 2005 Dec 7.


Restriction of apolipoprotein A-IV gene expression to the intestine villus depends on a hormone-responsive element and parallels differential expression of the hepatic nuclear factor 4alpha and gamma isoforms.

Sauvaget D, Chauffeton V, Citadelle D, Chatelet FP, Cywiner-Golenzer C, Chambaz J, Pinçon-Raymond M, Cardot P, Le Beyec J, Ribeiro A.

J Biol Chem. 2002 Sep 13;277(37):34540-8. Epub 2002 Jun 24.


Prostate cancer in bone: importance of context for inhibition of matrix metalloproteinases.

Bissell MJ, Le Beyec J, Anderson RL.

J Natl Cancer Inst. 2002 Jan 2;94(1):4-5. No abstract available.


Illegitimate expression of apolipoprotein A-II in Caco-2 cells is due to chromatin organization.

Le Beyec J, Ribeiro A, Schreider C, Chambaz J, Rousset M, Pinçon-Raymond M, Cardot P.

Exp Cell Res. 1999 Mar 15;247(2):373-9.


The -700/-310 fragment of the apolipoprotein A-IV gene combined with the -890/-500 apolipoprotein C-III enhancer is sufficient to direct a pattern of gene expression similar to that for the endogenous apolipoprotein A-IV gene.

Le Beyec J, Chauffeton V, Kan HY, Janvier PL, Cywiner-Golenzer C, Chatelet FP, Kalopissis AD, Zannis V, Chambaz J, Pinçon-Raymond M, Cardot P.

J Biol Chem. 1999 Feb 19;274(8):4954-61.


A complete epithelial organization of Caco-2 cells induces I-FABP and potentializes apolipoprotein gene expression.

Le Beyec J, Delers F, Jourdant F, Schreider C, Chambaz J, Cardot P, Pinçon-Raymond M.

Exp Cell Res. 1997 Oct 10;236(1):311-20.


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