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Items: 48


STING-dependent sensing of self-DNA drives silica-induced lung inflammation.

Benmerzoug S, Rose S, Bounab B, Gosset D, Duneau L, Chenuet P, Mollet L, Le Bert M, Lambers C, Geleff S, Roth M, Fauconnier L, Sedda D, Carvalho C, Perche O, Laurenceau D, Ryffel B, Apetoh L, Kiziltunc A, Uslu H, Albez FS, Akgun M, Togbe D, Quesniaux VFJ.

Nat Commun. 2018 Dec 6;9(1):5226. doi: 10.1038/s41467-018-07425-1.


PD-1 Is Involved in the Dysregulation of Type 2 Innate Lymphoid Cells in a Murine Model of Obesity.

Oldenhove G, Boucquey E, Taquin A, Acolty V, Bonetti L, Ryffel B, Le Bert M, Englebert K, Boon L, Moser M.

Cell Rep. 2018 Nov 20;25(8):2053-2060.e4. doi: 10.1016/j.celrep.2018.10.091.


The probiotic strain Escherichia coli Nissle 1917 prevents papain-induced respiratory barrier injury and severe allergic inflammation in mice.

Secher T, Maillet I, Mackowiak C, Le Bérichel J, Philippeau A, Panek C, Boury M, Oswald E, Saoudi A, Erard F, Le Bert M, Quesniaux V, Couturier-Maillard A, Ryffel B.

Sci Rep. 2018 Jul 26;8(1):11245. doi: 10.1038/s41598-018-29689-9.


The IL-33 Receptor ST2 Regulates Pulmonary Inflammation and Fibrosis to Bleomycin.

Fanny M, Nascimento M, Baron L, Schricke C, Maillet I, Akbal M, Riteau N, Le Bert M, Quesniaux V, Ryffel B, Gombault A, Même S, Même W, Couillin I.

Front Immunol. 2018 Jun 25;9:1476. doi: 10.3389/fimmu.2018.01476. eCollection 2018.


Pannexin-1 channels contribute to seizure generation in human epileptic brain tissue and in a mouse model of epilepsy.

Dossi E, Blauwblomme T, Moulard J, Chever O, Vasile F, Guinard E, Le Bert M, Couillin I, Pallud J, Capelle L, Huberfeld G, Rouach N.

Sci Transl Med. 2018 May 30;10(443). pii: eaar3796. doi: 10.1126/scitranslmed.aar3796.


Inducible CTCF insulator delays the IgH 3' regulatory region-mediated activation of germline promoters and alters class switching.

Braikia FZ, Oudinet C, Haddad D, Oruc Z, Orlando D, Dauba A, Le Bert M, Khamlichi AA.

Proc Natl Acad Sci U S A. 2017 Jun 6;114(23):6092-6097. doi: 10.1073/pnas.1701631114. Epub 2017 May 22.


Controlled Mycobacterium tuberculosis infection in mice under treatment with anti-IL-17A or IL-17F antibodies, in contrast to TNFα neutralization.

Segueni N, Tritto E, Bourigault ML, Rose S, Erard F, Le Bert M, Jacobs M, Di Padova F, Stiehl DP, Moulin P, Brees D, Chibout SD, Ryffel B, Kammüller M, Quesniaux VF.

Sci Rep. 2016 Nov 17;6:36923. doi: 10.1038/srep36923.


IL-1R1-MyD88 axis elicits papain-induced lung inflammation.

Agoro R, Piotet-Morin J, Palomo J, Michaudel C, Vigne S, Maillet I, Chenuet P, Guillou N, Le Bérichel J, Kisielow M, Flodby P, Borok Z, Crandall ED, Le Bert M, Quesniaux V, Muller M, Di Padova F, Ryffel B, Gabay C, Couturier-Maillard A.

Eur J Immunol. 2016 Nov;46(11):2531-2541. doi: 10.1002/eji.201646366. Epub 2016 Sep 22.


Protein kinase Cθ controls type 2 innate lymphoid cell and TH2 responses to house dust mite allergen.

Madouri F, Chenuet P, Beuraud C, Fauconnier L, Marchiol T, Rouxel N, Ledru A, Gallerand M, Lombardi V, Mascarell L, Marquant Q, Apetoh L, Erard F, Le Bert M, Trovero F, Quesniaux VFJ, Ryffel B, Togbe D.

J Allergy Clin Immunol. 2017 May;139(5):1650-1666. doi: 10.1016/j.jaci.2016.08.044. Epub 2016 Oct 14.


[Bone involvement in systemic mastocytosis: Report of two cases].

Florenzano P, Mezzano V, Le-Bert M, González G.

Rev Med Chil. 2016 Mar;144(3):401-5. doi: 10.4067/S0034-98872016000300018. Spanish.


Innate myeloid cell TNFR1 mediates first line defence against primary Mycobacterium tuberculosis infection.

Segueni N, Benmerzoug S, Rose S, Gauthier A, Bourigault ML, Reverchon F, Philippeau A, Erard F, Le Bert M, Bouscayrol H, Wachter T, Garcia I, Kollias G, Jacobs M, Ryffel B, Quesniaux VF.

Sci Rep. 2016 Mar 2;6:22454. doi: 10.1038/srep22454.


Unusual Ultrasound Appearance of Subungual Keratoacanthoma With Clinical and Histological Correlation.

Le-Bert M, Soto D, Vial V, Bentjerodt R, Wortsman X.

Actas Dermosifiliogr. 2016 Jun;107(5):442-4. doi: 10.1016/ Epub 2016 Jan 29. English, Spanish. No abstract available.


Complete cis Exclusion upon Duplication of the Eμ Enhancer at the Immunoglobulin Heavy Chain Locus.

Puget N, Leduc C, Oruc Z, Moutahir M, Le Bert M, Khamlichi AA.

Mol Cell Biol. 2015 Jul;35(13):2231-41.


The NLRP3 inflammasome is activated by nanoparticles through ATP, ADP and adenosine.

Baron L, Gombault A, Fanny M, Villeret B, Savigny F, Guillou N, Panek C, Le Bert M, Lagente V, Rassendren F, Riteau N, Couillin I.

Cell Death Dis. 2015 Feb 5;6:e1629. doi: 10.1038/cddis.2014.576.


Role of IL-1β in experimental cystic fibrosis upon P. aeruginosa infection.

Palomo J, Marchiol T, Piotet J, Fauconnier L, Robinet M, Reverchon F, Le Bert M, Togbe D, Buijs-Offerman R, Stolarczyk M, Quesniaux VF, Scholte BJ, Ryffel B.

PLoS One. 2014 Dec 12;9(12):e114884. doi: 10.1371/journal.pone.0114884. eCollection 2014.


Relative contribution of IL-1α, IL-1β and TNF to the host response to Mycobacterium tuberculosis and attenuated M. bovis BCG.

Bourigault ML, Segueni N, Rose S, Court N, Vacher R, Vasseur V, Erard F, Le Bert M, Garcia I, Iwakura Y, Jacobs M, Ryffel B, Quesniaux VF.

Immun Inflamm Dis. 2013 Oct;1(1):47-62. doi: 10.1002/iid3.9. Epub 2013 Oct 30.


Neutrophil Inhibitory Factor Selectively Inhibits the Endothelium-Driven Transmigration of Eosinophils In Vitro and Airway Eosinophilia in OVA-Induced Allergic Lung Inflammation.

Schnyder-Candrian S, Maillet I, Le Bert M, Brault L, Jacobs M, Ryffel B, Schnyder B, Moser R.

J Allergy (Cairo). 2012;2012:245909. doi: 10.1155/2012/245909. Epub 2012 Dec 4.


ATP release and purinergic signaling: a common pathway for particle-mediated inflammasome activation.

Riteau N, Baron L, Villeret B, Guillou N, Savigny F, Ryffel B, Rassendren F, Le Bert M, Gombault A, Couillin I.

Cell Death Dis. 2012 Oct 11;3:e403. doi: 10.1038/cddis.2012.144.


Inflammasome-IL-1-Th17 response in allergic lung inflammation.

Besnard AG, Togbe D, Couillin I, Tan Z, Zheng SG, Erard F, Le Bert M, Quesniaux V, Ryffel B.

J Mol Cell Biol. 2012 Feb;4(1):3-10. doi: 10.1093/jmcb/mjr042. Epub 2011 Dec 6. Review.


IL-1 and IL-23 mediate early IL-17A production in pulmonary inflammation leading to late fibrosis.

Gasse P, Riteau N, Vacher R, Michel ML, Fautrel A, di Padova F, Fick L, Charron S, Lagente V, Eberl G, Le Bert M, Quesniaux VF, Huaux F, Leite-de-Moraes M, Ryffel B, Couillin I.

PLoS One. 2011;6(8):e23185. doi: 10.1371/journal.pone.0023185. Epub 2011 Aug 16.


Sense transcription through the S region is essential for immunoglobulin class switch recombination.

Haddad D, Oruc Z, Puget N, Laviolette-Malirat N, Philippe M, Carrion C, Le Bert M, Khamlichi AA.

EMBO J. 2011 Apr 20;30(8):1608-20. doi: 10.1038/emboj.2011.56. Epub 2011 Mar 4.


Cigarette smoke-induced pulmonary inflammation is TLR4/MyD88 and IL-1R1/MyD88 signaling dependent.

Doz E, Noulin N, Boichot E, Guénon I, Fick L, Le Bert M, Lagente V, Ryffel B, Schnyder B, Quesniaux VF, Couillin I.

J Immunol. 2008 Jan 15;180(2):1169-78.


Replacement of Igamma3 germ-line promoter by Igamma1 inhibits class-switch recombination to IgG3.

Oruc Z, Boumédiène A, Le Bert M, Khamlichi AA.

Proc Natl Acad Sci U S A. 2007 Dec 18;104(51):20484-9. Epub 2007 Dec 11.


Tumor necrosis factor is critical to control tuberculosis infection.

Jacobs M, Togbe D, Fremond C, Samarina A, Allie N, Botha T, Carlos D, Parida SK, Grivennikov S, Nedospasov S, Monteiro A, Le Bert M, Quesniaux V, Ryffel B.

Microbes Infect. 2007 Apr;9(5):623-8. Epub 2007 Feb 21. Review.


Histological skin changes in heterozygote carriers of mutations in ABCC6, the gene causing pseudoxanthoma elasticum.

Martin L, Chassaing N, Delaite D, Estève E, Maître F, Le Bert M.

J Eur Acad Dermatol Venereol. 2007 Mar;21(3):368-73.


[Increased haemoglobin A2 levels in pseudoxanthoma elasticum].

Martin L, Pissard S, Blanc P, Chassaing N, Legac E, Briault S, Le Bert M, Le Saux O.

Ann Dermatol Venereol. 2006 Aug-Sep;133(8-9 Pt 1):645-51. French.


The 5'HS4 insulator element is an efficient tool to analyse the transient expression of an Em mu-GFP vector in a transgenic mouse model.

Guglielmi L, Truffinet V, Carrion C, Le Bert M, Cogné N, Cogné M, Denizot Y.

Transgenic Res. 2005 Aug;14(4):361-4. No abstract available.


Pseudoxanthoma elasticum: a clinical, pathophysiological and genetic update including 11 novel ABCC6 mutations.

Chassaing N, Martin L, Calvas P, Le Bert M, Hovnanian A.

J Med Genet. 2005 Dec;42(12):881-92. Epub 2005 May 13. Review.


Bidirectional transcriptional activity of the Pgk1 promoter and transmission ratio distortion in Capn3-deficient mice.

Taveau M, Stockholm D, Marchand S, Roudaut C, Le Bert M, Richard I.

Genomics. 2004 Sep;84(3):592-5.


Toll-like receptor pathways in the immune responses to mycobacteria.

Quesniaux V, Fremond C, Jacobs M, Parida S, Nicolle D, Yeremeev V, Bihl F, Erard F, Botha T, Drennan M, Soler MN, Le Bert M, Schnyder B, Ryffel B.

Microbes Infect. 2004 Aug;6(10):946-59. Review.


Mouse embryonic stem cell sorting for the generation of transgenic mice by sedimentation field-flow fractionation.

Guglielmi L, Battu S, Le Bert M, Faucher JL, Cardot PJ, Denizot Y.

Anal Chem. 2004 Mar 15;76(6):1580-5.


Immunoglobulin class-switch recombination in mice devoid of any S mu tandem repeat.

Khamlichi AA, Glaudet F, Oruc Z, Denis V, Le Bert M, Cogné M.

Blood. 2004 May 15;103(10):3828-36. Epub 2004 Feb 12.


Combination of 3' and 5' IgH regulatory elements mimics the B-specific endogenous expression pattern of IgH genes from pro-B cells to mature B cells in a transgenic mouse model.

Guglielmi L, Le Bert M, Comte I, Dessain ML, Drouet M, Ayer-Le Lievre C, Cogné M, Denizot Y.

Biochim Biophys Acta. 2003 Oct 21;1642(3):181-90.


Insulators to improve expression of a 3(')IgH LCR-driven reporter gene in transgenic mouse models.

Guglielmi L, Le Bert M, Truffinet V, Cogné M, Denizot Y.

Biochem Biophys Res Commun. 2003 Aug 1;307(3):466-71.


Effect of the Emu IgH enhancer on expression of a GFP reporter gene in transfected B cells and transgenic mice.

Guglielmi L, Le Bert M, Cogné M, Denizot Y.

Immunol Lett. 2003 Mar 3;86(1):77-83.


Localization of the 3' IgH locus elements that effect long-distance regulation of class switch recombination.

Pinaud E, Khamlichi AA, Le Morvan C, Drouet M, Nalesso V, Le Bert M, Cogné M.

Immunity. 2001 Aug;15(2):187-99.


Can cellular transplantation improve function in doxorubicin-induced heart failure?

Scorsin M, Hagege AA, Dolizy I, Marotte F, Mirochnik N, Copin H, Barnoux M, le Bert M, Samuel JL, Rappaport L, Menasché P.

Circulation. 1998 Nov 10;98(19 Suppl):II151-5; discussion II155-6.


Alternatively spliced focal adhesion kinase in rat brain with increased autophosphorylation activity.

Burgaya F, Toutant M, Studler JM, Costa A, Le Bert M, Gelman M, Girault JA.

J Biol Chem. 1997 Nov 7;272(45):28720-5.


Paranodin, a glycoprotein of neuronal paranodal membranes.

Menegoz M, Gaspar P, Le Bert M, Galvez T, Burgaya F, Palfrey C, Ezan P, Arnos F, Girault JA.

Neuron. 1997 Aug;19(2):319-31.


Regulation of a neuronal form of focal adhesion kinase by anandamide.

Derkinderen P, Toutant M, Burgaya F, Le Bert M, Siciliano JC, de Franciscis V, Gelman M, Girault JA.

Science. 1996 Sep 20;273(5282):1719-22.


Immortalization of different precursors of glial cells with a targeted and temperature-sensitive oncogene.

Bernard R, Le Bert M, Borde I, Galiana E, Evrard C, Rouget P.

Exp Cell Res. 1994 Sep;214(1):373-80.


Seizure-related opening of the blood-brain barrier induced by soman: possible correlation with the acute neuropathology observed in poisoned rats.

Carpentier P, Delamanche IS, Le Bert M, Blanchet G, Bouchaud C.

Neurotoxicology. 1990 Fall;11(3):493-508.


[Consultation on morbidity in adolescents in primary care].

López IM, Romero MI, Vargas S, Rojas D, Aranda W, Le Bert M, Guerrero MA.

Rev Chil Pediatr. 1985 Sep-Oct;56(5):359-61. Spanish. No abstract available.


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