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Items: 1 to 50 of 272

1.

In vivo biased agonism at 5-HT1A receptors: characterisation by simultaneous PET/MR imaging.

Vidal B, Fieux S, Redouté J, Villien M, Bonnefoi F, Le Bars D, Newman-Tancredi A, Costes N, Zimmer L.

Neuropsychopharmacology. 2018 Jul 6. doi: 10.1038/s41386-018-0145-2. [Epub ahead of print]

PMID:
30030540
2.

Frontal Transcranial Direct Current Stimulation Induces Dopamine Release in the Ventral Striatum in Human.

Fonteneau C, Redoute J, Haesebaert F, Le Bars D, Costes N, Suaud-Chagny MF, Brunelin J.

Cereb Cortex. 2018 Jul 1;28(7):2636-2646. doi: 10.1093/cercor/bhy093.

3.

AGE Content of a Protein Load Is Responsible for Renal Performances: A Pilot Study.

Normand G, Lemoine S, Villien M, Le Bars D, Merida I, Irace Z, Troalen T, Costes N, Juillard L.

Diabetes Care. 2018 Jun;41(6):1292-1294. doi: 10.2337/dc18-0131. Epub 2018 Apr 2.

PMID:
29610272
4.

Oxytocin Fails to Recruit Serotonergic Neurotransmission in the Autistic Brain.

Lefevre A, Mottolese R, Redouté J, Costes N, Le Bars D, Geoffray MM, Leboyer M, Sirigu A.

Cereb Cortex. 2017 Oct 17:1-10. doi: 10.1093/cercor/bhx272. [Epub ahead of print]

PMID:
29045584
5.

Entanglement between thermoregulation and nociception in the rat: the case of morphine.

El Bitar N, Pollin B, Karroum E, Pincedé I, Le Bars D.

J Neurophysiol. 2016 Dec 1;116(6):2473-2496. doi: 10.1152/jn.00482.2016. Epub 2016 Sep 7.

6.

The prominent role of serotonergic degeneration in apathy, anxiety and depression in de novo Parkinson's disease.

Maillet A, Krack P, Lhommée E, Météreau E, Klinger H, Favre E, Le Bars D, Schmitt E, Bichon A, Pelissier P, Fraix V, Castrioto A, Sgambato-Faure V, Broussolle E, Tremblay L, Thobois S.

Brain. 2016 Sep;139(Pt 9):2486-502. doi: 10.1093/brain/aww162. Epub 2016 Aug 17.

PMID:
27538418
7.

Direct Electrophilic (Benzenesulfonyl)Difluoromethylthiolation with a Shelf-Stable Reagent.

Ismalaj E, Le Bars D, Billard T.

Angew Chem Int Ed Engl. 2016 Apr 4;55(15):4790-3. doi: 10.1002/anie.201601280. Epub 2016 Mar 8.

PMID:
27037994
8.

The rostral ventromedial medulla control of cutaneous vasomotion of paws and tail in the rat: implication for pain studies.

El Bitar N, Pollin B, Huang G, Mouraux A, Le Bars D.

J Neurophysiol. 2016 Feb 1;115(2):773-89. doi: 10.1152/jn.00695.2015. Epub 2015 Nov 18.

9.

Neural substrates of levodopa-responsive gait disorders and freezing in advanced Parkinson's disease: a kinesthetic imagery approach.

Maillet A, Thobois S, Fraix V, Redouté J, Le Bars D, Lavenne F, Derost P, Durif F, Bloem BR, Krack P, Pollak P, Debû B.

Hum Brain Mapp. 2015 Mar;36(3):959-80. doi: 10.1002/hbm.22679. Epub 2014 Nov 19.

PMID:
25411130
10.

"On-" and "off-" cells in the rostral ventromedial medulla of rats held in thermoneutral conditions: are they involved in thermoregulation?

El Bitar N, Pollin B, Le Bars D.

J Neurophysiol. 2014 Nov 1;112(9):2199-217. doi: 10.1152/jn.00722.2013. Epub 2014 Jul 9.

11.

Thermoregulatory vasomotor tone of the rat tail and paws in thermoneutral conditions and its impact on a behavioral model of acute pain.

El Bitar N, Pollin B, Karroum E, Pincedé I, Mouraux A, Le Bars D.

J Neurophysiol. 2014 Nov 1;112(9):2185-98. doi: 10.1152/jn.00721.2013. Epub 2014 Jul 9.

12.

Switching brain serotonin with oxytocin.

Mottolese R, Redouté J, Costes N, Le Bars D, Sirigu A.

Proc Natl Acad Sci U S A. 2014 Jun 10;111(23):8637-42. doi: 10.1073/pnas.1319810111. Epub 2014 May 27.

13.

Accuracy of distinguishing between dysembryoplastic neuroepithelial tumors and other epileptogenic brain neoplasms with [¹¹C]methionine PET.

Rheims S, Rubi S, Bouvard S, Bernard E, Streichenberger N, Guenot M, Le Bars D, Hammers A, Ryvlin P.

Neuro Oncol. 2014 Oct;16(10):1417-26. doi: 10.1093/neuonc/nou022. Epub 2014 Mar 5.

14.

Positron emission tomography with α-[11C]methyl-L-tryptophan in tuberous sclerosis complex-related epilepsy.

Rubí S, Costes N, Heckemann RA, Bouvard S, Hammers A, Martí Fuster B, Ostrowsky K, Montavont A, Jung J, Setoain X, Catenoix H, Hino K, Liger F, Le Bars D, Ryvlin P.

Epilepsia. 2013 Dec;54(12):2143-50. doi: 10.1111/epi.12412. Epub 2013 Oct 28.

15.

Current status of positron emission tomography radiotracers for serotonin receptors in humans.

Zimmer L, Le Bars D.

J Labelled Comp Radiopharm. 2013 Mar-Apr;56(3-4):105-13. doi: 10.1002/jlcr.3001. Review.

PMID:
24285316
16.

PET radiotracers for molecular imaging of serotonin 5-HT1A receptors.

Billard T, Le Bars D, Zimmer L.

Curr Med Chem. 2014;21(1):70-81. Review.

PMID:
23992341
17.

Noninvasive quantitative assessment of pulmonary blood flow with 18F-FDG PET.

Pouzot C, Richard JC, Gros A, Costes N, Lavenne F, Le Bars D, Guerin C.

J Nucl Med. 2013 Sep;54(9):1653-60. doi: 10.2967/jnumed.112.116699. Epub 2013 Aug 1.

18.

A multi-atlas based method for automated anatomical Macaca fascicularis brain MRI segmentation and PET kinetic extraction.

Ballanger B, Tremblay L, Sgambato-Faure V, Beaudoin-Gobert M, Lavenne F, Le Bars D, Costes N.

Neuroimage. 2013 Aug 15;77:26-43. doi: 10.1016/j.neuroimage.2013.03.029. Epub 2013 Mar 26.

PMID:
23537938
19.

Mechanical allodynia in neuropathic pain. Where are the brain representations located? A positron emission tomography (PET) study.

Peyron R, Faillenot I, Pomares FB, Le Bars D, Garcia-Larrea L, Laurent B.

Eur J Pain. 2013 Oct;17(9):1327-37. doi: 10.1002/j.1532-2149.2013.00307.x. Epub 2013 Mar 27.

PMID:
23536357
20.

Psychophysics of a nociceptive test in the mouse: ambient temperature as a key factor for variation.

Pincedé I, Pollin B, Meert T, Plaghki L, Le Bars D.

PLoS One. 2012;7(5):e36699. doi: 10.1371/journal.pone.0036699. Epub 2012 May 18.

21.

Ventricular muscarinic receptor remodeling in patients with and without primary ventricular fibrillation. An imaging study.

Mazzadi AN, Pineau J, Costes N, Le Bars D, Bonnefoi F, Porcher R, Croisille P, Chevalier P.

J Nucl Cardiol. 2012 Oct;19(5):1017-25. doi: 10.1007/s12350-012-9576-z. Epub 2012 May 17.

PMID:
22592514
22.

Role of serotonergic 1A receptor dysfunction in depression associated with Parkinson's disease.

Ballanger B, Klinger H, Eche J, Lerond J, Vallet AE, Le Bars D, Tremblay L, Sgambato-Faure V, Broussolle E, Thobois S.

Mov Disord. 2012 Jan;27(1):84-9. doi: 10.1002/mds.23895. Epub 2011 Oct 12.

PMID:
21994070
23.

Comparison of 4 radiolabeled antagonists for serotonin 5-HT(7) receptor neuroimaging: toward the first PET radiotracer.

Lemoine L, Andries J, Le Bars D, Billard T, Zimmer L.

J Nucl Med. 2011 Nov;52(11):1811-8. doi: 10.2967/jnumed.111.089185. Epub 2011 Oct 11.

24.

Synthesis and biological evaluation of potential 5-HT(7) receptor PET radiotracers.

Andries J, Lemoine L, Le Bars D, Zimmer L, Billard T.

Eur J Med Chem. 2011 Aug;46(8):3455-61. doi: 10.1016/j.ejmech.2011.05.010. Epub 2011 May 12.

PMID:
21620533
25.

Dose-dependent opposite effects of gabapentin on the depressive action of morphine on a C-fibre reflex in the rat.

Pollin B, Roy-Ledoux R, le Bars D, Adam F.

Neuropharmacology. 2011 Sep;61(4):551-7. doi: 10.1016/j.neuropharm.2011.04.020. Epub 2011 May 6.

PMID:
21570415
26.

In vivo demonstration of amyloid burden in posterior cortical atrophy: a case series with PET and CSF findings.

Formaglio M, Costes N, Seguin J, Tholance Y, Le Bars D, Roullet-Solignac I, Mercier B, Krolak-Salmon P, Vighetto A.

J Neurol. 2011 Oct;258(10):1841-51. doi: 10.1007/s00415-011-6030-0. Epub 2011 Apr 10.

PMID:
21479849
27.

A reassessment of stress-induced "analgesia" in the rat using an unbiased method.

Carrive P, Churyukanov M, Le Bars D.

Pain. 2011 Mar;152(3):676-86. doi: 10.1016/j.pain.2010.12.019. Epub 2011 Jan 28.

PMID:
21277086
28.

Chronic low-back pain modulation is enhanced by hypnotic analgesic suggestion by recruiting an emotional network: a PET imaging study.

Nusbaum F, Redouté J, Le Bars D, Volckmann P, Simon F, Hannoun S, Ribes G, Gaucher J, Laurent B, Sappey-Marinier D.

Int J Clin Exp Hypn. 2011 Jan;59(1):27-44. doi: 10.1080/00207144.2011.522874.

PMID:
21104483
29.

18F-FLT and 18F-FDG positron emission tomography for the imaging of advanced well-differentiated gastro-entero-pancreatic endocrine tumours.

Giammarile F, Billotey C, Lombard-Bohas C, Le Bars D, Bournaud C, Masson S, Walter T, Houzard C, Scoazec JY, Hervieu V, Vuillez JP, Cornu C, Janier M, Borson-Chazot F.

Nucl Med Commun. 2011 Feb;32(2):91-7. doi: 10.1097/MNM.0b013e3283412143.

PMID:
21076344
30.

Looking for a 5-HT7 radiotracer for positron emission tomography.

Andriès J, Lemoine L, Mouchel-Blaisot A, Tang S, Verdurand M, Le Bars D, Zimmer L, Billard T.

Bioorg Med Chem Lett. 2010 Jun 15;20(12):3730-3. doi: 10.1016/j.bmcl.2010.04.076. Epub 2010 Apr 24.

PMID:
20471259
31.

The fine tuning of pain thresholds: a sophisticated double alarm system.

Plaghki L, Decruynaere C, Van Dooren P, Le Bars D.

PLoS One. 2010 Apr 23;5(4):e10269. doi: 10.1371/journal.pone.0010269.

32.

Muscarinic receptor upregulation in patients with myocardial infarction: a new paradigm.

Mazzadi AN, Pineau J, Costes N, Le Bars D, Bonnefoi F, Croisille P, Porcher R, Chevalier P.

Circ Cardiovasc Imaging. 2009 Sep;2(5):365-72. doi: 10.1161/CIRCIMAGING.108.822106. Epub 2009 Jul 7.

PMID:
19808624
33.

[18F]F15599, a novel 5-HT1A receptor agonist, as a radioligand for PET neuroimaging.

Lemoine L, Verdurand M, Vacher B, Blanc E, Le Bars D, Newman-Tancredi A, Zimmer L.

Eur J Nucl Med Mol Imaging. 2010 Mar;37(3):594-605. doi: 10.1007/s00259-009-1274-y. Epub 2009 Sep 30.

PMID:
19789870
34.

Freezing of enkephalinergic functions by multiple noxious foci: a source of pain sensitization?

Cesselin F, Bourgoin S, Mauborgne A, Hamon M, Le Bars D.

PLoS One. 2009 Sep 3;4(9):e6874. doi: 10.1371/journal.pone.0006874.

35.

Association between triallelic polymorphism of the serotonin transporter and [18F]MPPF binding potential at 5-HT1A receptors in healthy subjects.

Lothe A, Boni C, Costes N, Gorwood P, Bouvard S, Le Bars D, Lavenne F, Ryvlin P.

Neuroimage. 2009 Aug 15;47(2):482-92. doi: 10.1016/j.neuroimage.2009.04.067. Epub 2009 May 3.

PMID:
19409499
36.

Effects of amyloid-β peptides on the serotoninergic 5-HT1A receptors in the rat hippocampus.

Verdurand M, Bérod A, Le Bars D, Zimmer L.

Neurobiol Aging. 2011 Jan;32(1):103-14. doi: 10.1016/j.neurobiolaging.2009.01.008. Epub 2009 Feb 26.

PMID:
19249128
37.

Letter to the editor of Pain about Gemma Ford and David Finn, Clinical correlates of stress-induced analgesia: evidence from pharmacological study. Pain 2008;140:3-7.

Le Bars D, Carrive P.

Pain. 2009 Mar;142(1-2):165-7; author reply 167-8. doi: 10.1016/j.pain.2009.01.009. Epub 2009 Feb 5. No abstract available.

PMID:
19200659
38.

Peripheral and central determinants of a nociceptive reaction: an approach to psychophysics in the rat.

Benoist JM, Pincedé I, Ballantyne K, Plaghki L, Le Bars D.

PLoS One. 2008 Sep 3;3(9):e3125. doi: 10.1371/journal.pone.0003125.

39.

Automated radiosynthesis of the Pittsburg compound-B using a commercial synthesizer.

Verdurand M, Bort G, Tadino V, Bonnefoi F, Le Bars D, Zimmer L.

Nucl Med Commun. 2008 Oct;29(10):920-6. doi: 10.1097/MNM.0b013e328304e0e1.

PMID:
18769311
40.

Organic background of restrictive-type anorexia nervosa suggested by increased serotonin 1A receptor binding in right frontotemporal cortex of both lean and recovered patients: [18F]MPPF PET scan study.

Galusca B, Costes N, Zito NG, Peyron R, Bossu C, Lang F, Le Bars D, Estour B.

Biol Psychiatry. 2008 Dec 1;64(11):1009-13. doi: 10.1016/j.biopsych.2008.06.006. Epub 2008 Jul 18.

PMID:
18639866
41.

[Fluorine-18 in radiopharmacy].

de Beco V, Le Bars D, Scherrmann JM.

Ann Pharm Fr. 2008 Jan;66(1):60-5. doi: 10.1016/j.pharma.2007.12.002. Epub 2008 Mar 28. Review. French.

PMID:
18435989
42.

Motor urgency is mediated by the contralateral cerebellum in Parkinson's disease.

Ballanger B, Baraduc P, Broussolle E, Le Bars D, Desmurget M, Thobois S.

J Neurol Neurosurg Psychiatry. 2008 Oct;79(10):1110-6. doi: 10.1136/jnnp.2007.141689. Epub 2008 Mar 20.

PMID:
18356249
43.

A distinct [18F]MPPF PET profile in amnestic mild cognitive impairment compared to mild Alzheimer's disease.

Truchot L, Costes N, Zimmer L, Laurent B, Le Bars D, Thomas-Antérion C, Mercier B, Hermier M, Vighetto A, Krolak-Salmon P.

Neuroimage. 2008 Apr 15;40(3):1251-6. doi: 10.1016/j.neuroimage.2008.01.030. Epub 2008 Feb 1.

PMID:
18313943
44.

Globus pallidus stimulation reduces frontal hyperactivity in tardive dystonia.

Thobois S, Ballanger B, Xie-Brustolin J, Damier P, Durif F, Azulay JP, Derost P, Witjas T, Raoul S, Le Bars D, Broussolle E.

J Cereb Blood Flow Metab. 2008 Jun;28(6):1127-38. doi: 10.1038/sj.jcbfm.9600610. Epub 2008 Jan 30.

PMID:
18231115
45.

The glycine site-specific NMDA antagonist (+)-HA966 enhances the effect of morphine and reverses morphine tolerance via a spinal mechanism.

Adam F, Dufour E, Le Bars D.

Neuropharmacology. 2008 Mar;54(3):588-96. doi: 10.1016/j.neuropharm.2007.11.013. Epub 2007 Nov 28.

PMID:
18177675
46.

In vitro and in vivo studies with [(18)F]fluorocholine on digestive tumoral cell lines and in an animal model of metastasized endocrine tumor.

Nejjari M, Kryza D, Poncet G, Roche C, Perek N, Chayvialle JA, Le Bars D, Scoazec JY, Janier M, Borson-Chazot F.

Nucl Med Biol. 2008 Jan;35(1):123-30.

PMID:
18158951
47.

Synthesis and biological evaluation in rat and cat of [18F]12ST05 as a potential 5-HT6 PET radioligand.

Tang S, Verdurand M, Joseph B, Lemoine L, Daoust A, Billard T, Fournet G, Le Bars D, Zimmer L.

Nucl Med Biol. 2007 Nov;34(8):995-1002. Epub 2007 Sep 21.

PMID:
17998104
48.

Ultra violet-induced localized inflammatory hyperalgesia in awake rats and the role of sensory and sympathetic innervation of the skin.

Saadé NE, Farhat O, Rahal O, Safieh-Garabedian B, Le Bars D, Jabbur SJ.

Brain Behav Immun. 2008 Feb;22(2):245-56. Epub 2007 Sep 19.

PMID:
17884331
49.

Formation of diacetyl and acetoin by Lactococcus lactis via aspartate catabolism.

Le Bars D, Yvon M.

J Appl Microbiol. 2008 Jan;104(1):171-7.

50.

Up-regulation of hippocampal serotonin metabolism in mild cognitive impairment.

Truchot L, Costes SN, Zimmer L, Laurent B, Le Bars D, Thomas-Antérion C, Croisile B, Mercier B, Hermier M, Vighetto A, Krolak-Salmon P.

Neurology. 2007 Sep 4;69(10):1012-7.

PMID:
17785670

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