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Year Number of Results
2009 4
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Association analysis of LCE3C-LCE3B deletion in Tunisian psoriatic population.
Ammar M, Bouazizi F, Bouhaha R, Zaraa I, Kouidhi S, Ourheni S, Helms C, Doss N, Dhaoui R, Ben Osman A, Ben Ammar-El Gaaïed A, Marrakchi R, Mokni M, Bouchlaka-Souissi C. Ammar M, et al. Arch Dermatol Res. 2012 Nov;304(9):733-8. doi: 10.1007/s00403-012-1279-4. Epub 2012 Aug 29. Arch Dermatol Res. 2012. PMID: 22926764
An association between a common deletion comprising the late cornified envelope LCE3B and LCE3C genes (LCE3C_LCE3B-del) and psoriasis has been reported in Caucasian and Asian populations. ...Our findings indicate that the LCE3C_LCE3B-del might play a role in …
An association between a common deletion comprising the late cornified envelope LCE3B and LCE3C genes (LCE3C_LCE3B-del) and ps …
Association between the LCE3C_LCE3B deletion polymorphism and susceptibility to psoriasis: a meta-analysis of published studies.
Song GG, Kim JH, Lee YH. Song GG, et al. Genet Test Mol Biomarkers. 2013 Jul;17(7):572-7. doi: 10.1089/gtmb.2013.0030. Epub 2013 Apr 30. Genet Test Mol Biomarkers. 2013. PMID: 23631431
OBJECTIVE: To determine whether a deletion comprising the LCE3C and LCE3B genes (LCE3C_LCE3B-del) confers susceptibility to psoriasis. ...Meta-analysis of the LCE3C_LCE3B-del allele showed no association between psoriatic arthritis and the LCE3C_LCE3B- …
OBJECTIVE: To determine whether a deletion comprising the LCE3C and LCE3B genes (LCE3C_LCE3B-del) confers susceptibility to ps …
Antimicrobial Late Cornified Envelope Proteins: The Psoriasis Risk Factor Deletion of LCE3B/C Genes Affects Microbiota Composition.
Niehues H, van der Krieken DA, Ederveen THA, Jansen PAM, van Niftrik L, Mesman R, Netea MG, Smits JPH, Schalkwijk J, van den Bogaard EH, Zeeuwen PLJM. Niehues H, et al. J Invest Dermatol. 2022 Jul;142(7):1947-1955.e6. doi: 10.1016/j.jid.2021.11.036. Epub 2021 Dec 21. J Invest Dermatol. 2022. PMID: 34942199 Free article.
The LCE3 proteins have been the focus of dermatological research because the combined deletion of LCE3B and LCE3C genes (LCE3B/C-del) is a risk factor for psoriasis. We previously reported that LCE3B/C-del increases the expression of the LCE3A gene and that L …
The LCE3 proteins have been the focus of dermatological research because the combined deletion of LCE3B and LCE3C genes (LCE3B …
Mutation analysis of the LCE3B/LCE3C genes in Psoriasis.
Coto E, Santos-Juanes J, Coto-Segura P, Díaz M, Soto J, Queiro R, Alvarez V. Coto E, et al. BMC Med Genet. 2010 Mar 23;11:45. doi: 10.1186/1471-2350-11-45. BMC Med Genet. 2010. PMID: 20331852 Free PMC article.
BACKGROUND: An association between a common deletion comprising the late cornified envelope LCE3B and LCE3C genes (LCE3C_LCE3B-del) and Psoriasis (Ps) has been reported. ...The analysis of the coding sequence of LCE3B and LCE3C in the patients who had at leas …
BACKGROUND: An association between a common deletion comprising the late cornified envelope LCE3B and LCE3C genes (LCE3C_LCE3B …
Deletion of LCE3C_LCE3B is associated with rheumatoid arthritis and systemic lupus erythematosus in the Chinese Han population.
Lu X, Guo J, Zhou X, Li R, Liu X, Zhao Y, Zhu B, Liu X, Xu J, Zhu P, Wu X, He J, Liu X, Zhang H, Li Z. Lu X, et al. Ann Rheum Dis. 2011 Sep;70(9):1648-51. doi: 10.1136/ard.2010.148072. Epub 2011 May 30. Ann Rheum Dis. 2011. PMID: 21628307
OBJECTIVES: The deletion of LCE3C_LCE3B confers susceptibility to psoriasis and rheumatoid arthritis (RA) in Caucasians. ...CONCLUSIONS: This study provides evidence for an association between LCE3C_LCE3B-del and RA in non-Caucasian populations, and SNPs rs4112788 a …
OBJECTIVES: The deletion of LCE3C_LCE3B confers susceptibility to psoriasis and rheumatoid arthritis (RA) in Caucasians. ...CONCLUSIO …
Deletion of LCE3C and LCE3B is a susceptibility factor for psoriatic arthritis: a study in Spanish and Italian populations and meta-analysis.
Docampo E, Giardina E, Riveira-Muñoz E, de Cid R, Escaramís G, Perricone C, Fernández-Sueiro JL, Maymó J, González-Gay MA, Blanco FJ, Hüffmeier U, Lisbona MP, Martín J, Carracedo A, Reis A, Rabionet R, Novelli G, Estivill X. Docampo E, et al. Arthritis Rheum. 2011 Jul;63(7):1860-5. doi: 10.1002/art.30340. Arthritis Rheum. 2011. PMID: 21400479 Free article.
OBJECTIVE: The LCE3C_LCE3B-del variant is associated with psoriasis and rheumatoid arthritis. ...Meta-analysis including data from all previous published studies confirmed an association of PsA with the LCE3C_LCE3B-del tag SNP. CONCLUSION: LCE3C_LCE3B-del is …
OBJECTIVE: The LCE3C_LCE3B-del variant is associated with psoriasis and rheumatoid arthritis. ...Meta-analysis including data from al …
Psoriasis: An Immunogenetic Perspective.
Kocaaga A, Kocaaga M. Kocaaga A, et al. Glob Med Genet. 2022 Jun 13;9(2):82-89. doi: 10.1055/s-0042-1743259. eCollection 2022 Jun. Glob Med Genet. 2022. PMID: 35707771 Free PMC article. Review.
To date, >70 psoriasis susceptibility loci have been identified, including HLA-Cw6, IL12B, IL23R, and LCE3B/3C. Some genetic markers are used in clinical diagnosis, prognosis, treatment, and personalized new drug development that can further explain the pathogenesis of …
To date, >70 psoriasis susceptibility loci have been identified, including HLA-Cw6, IL12B, IL23R, and LCE3B/3C. Some genetic marke …
Deletion of LCE3C and LCE3B genes is associated with psoriasis in a northern Chinese population.
Xu L, Li Y, Zhang X, Sun H, Sun D, Jia X, Shen C, Zhou J, Ji G, Liu P, Guan R, Yu Y, Jin Y, Bai J, Sun D, Yu J, Fu S. Xu L, et al. Br J Dermatol. 2011 Oct;165(4):882-7. doi: 10.1111/j.1365-2133.2011.10485.x. Br J Dermatol. 2011. PMID: 21711330
BACKGROUND: It has been shown that a deletion in the late cornified envelope (LCE) gene cluster (LCE3C_LCE3B-del) is associated with susceptibility to psoriasis in European populations. ...In subgroup analysis, the distribution was significantly different between patients …
BACKGROUND: It has been shown that a deletion in the late cornified envelope (LCE) gene cluster (LCE3C_LCE3B-del) is associated with …
Deletion of late cornified envelope genes, LCE3C_LCE3B-del, is not associated with psoriatic arthritis in Tunisian patients.
Chiraz BS, Myriam A, Ines Z, Catherine J, Fatma B, Ilhem C, Raoudha T, Hela Z, Hela F, Elyes B, Nejib D, Cindy H, Amel E, Slaheddine S. Chiraz BS, et al. Mol Biol Rep. 2014 Jun;41(6):4141-6. doi: 10.1007/s11033-014-3285-4. Epub 2014 Feb 25. Mol Biol Rep. 2014. PMID: 24566688
To assess whether this deletion may contribute to the genetic predisposition to PsA in Tunisia, a total of 73 patients with PsA and 120 healthy matched controls were screened for the deletion, LCE3C_LCE3B-del, and its tag SNP, rs4112788. We also evaluated a possible relati …
To assess whether this deletion may contribute to the genetic predisposition to PsA in Tunisia, a total of 73 patients with PsA and 120 heal …
Deletion of the late cornified envelope LCE3B and LCE3C genes as a susceptibility factor for psoriasis.
de Cid R, Riveira-Munoz E, Zeeuwen PL, Robarge J, Liao W, Dannhauser EN, Giardina E, Stuart PE, Nair R, Helms C, Escaramís G, Ballana E, Martín-Ezquerra G, den Heijer M, Kamsteeg M, Joosten I, Eichler EE, Lázaro C, Pujol RM, Armengol L, Abecasis G, Elder JT, Novelli G, Armour JA, Kwok PY, Bowcock A, Schalkwijk J, Estivill X. de Cid R, et al. Nat Genet. 2009 Feb;41(2):211-5. doi: 10.1038/ng.313. Epub 2009 Jan 25. Nat Genet. 2009. PMID: 19169253 Free PMC article.
The absence of LCE3B and LCE3C (LCE3C_LCE3B-del) is significantly associated (P = 1.38E-08) with risk of psoriasis in 2,831 samples from Spain, The Netherlands, Italy and the United States, and in a family-based study (P = 5.4E-04). LCE3C_LCE3B-del is tagged …
The absence of LCE3B and LCE3C (LCE3C_LCE3B-del) is significantly associated (P = 1.38E-08) with risk of psoriasis in 2,831 sa …
57 results