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Items: 15


Insulin-like growth factor receptor signaling in breast tumor epithelium protects cells from endoplasmic reticulum stress and regulates the tumor microenvironment.

Obr AE, Kumar S, Chang YJ, Bulatowicz JJ, Barnes BJ, Birge RB, Lazzarino DA, Gallagher E, LeRoith D, Wood TL.

Breast Cancer Res. 2018 Nov 20;20(1):138. doi: 10.1186/s13058-018-1063-2.


IGF1R inhibition in mammary epithelia promotes canonical Wnt signaling and Wnt1-driven tumors.

Rota LM, Albanito L, Shin ME, Goyeneche CL, Shushanov S, Gallagher EJ, LeRoith D, Lazzarino DA, Wood TL.

Cancer Res. 2014 Oct 1;74(19):5668-79. doi: 10.1158/0008-5472.CAN-14-0970. Epub 2014 Aug 4.


Determining mammosphere-forming potential: application of the limiting dilution analysis.

Rota LM, Lazzarino DA, Ziegler AN, LeRoith D, Wood TL.

J Mammary Gland Biol Neoplasia. 2012 Jun;17(2):119-23. doi: 10.1007/s10911-012-9258-0. Epub 2012 Jun 8. Review.


Elevated circulating IGF-I promotes mammary gland development and proliferation.

Cannata D, Lann D, Wu Y, Elis S, Sun H, Yakar S, Lazzarino DA, Wood TL, Leroith D.

Endocrinology. 2010 Dec;151(12):5751-61. doi: 10.1210/en.2010-0792. Epub 2010 Oct 6.


Insulin-mediated acceleration of breast cancer development and progression in a nonobese model of type 2 diabetes.

Novosyadlyy R, Lann DE, Vijayakumar A, Rowzee A, Lazzarino DA, Fierz Y, Carboni JM, Gottardis MM, Pennisi PA, Molinolo AA, Kurshan N, Mejia W, Santopietro S, Yakar S, Wood TL, LeRoith D.

Cancer Res. 2010 Jan 15;70(2):741-51. doi: 10.1158/0008-5472.CAN-09-2141. Epub 2010 Jan 12.


Brain injury expands the numbers of neural stem cells and progenitors in the SVZ by enhancing their responsiveness to EGF.

Alagappan D, Lazzarino DA, Felling RJ, Balan M, Kotenko SV, Levison SW.

ASN Neuro. 2009 May 20;1(2). pii: e00009. doi: 10.1042/AN20090002.


IGF ligand and receptor regulation of mammary development.

Rowzee AM, Lazzarino DA, Rota L, Sun Z, Wood TL.

J Mammary Gland Biol Neoplasia. 2008 Dec;13(4):361-70. doi: 10.1007/s10911-008-9102-8. Epub 2008 Nov 20. Review.


Insulin-like growth factor type-I receptor internalization and recycling mediate the sustained phosphorylation of Akt.

Romanelli RJ, LeBeau AP, Fulmer CG, Lazzarino DA, Hochberg A, Wood TL.

J Biol Chem. 2007 Aug 3;282(31):22513-24. Epub 2007 Jun 1.


IL-8 and MCP-1 secretion is enhanced by the peptide-nucleic acid immunomodulator, Product R, in U937 cells and primary human monocytes.

Lazzarino DA, de Diego M, Hirschman SZ, Zhang KY, Shaikh S, Musi E, Liaw L, Alexander RJ.

Cytokine. 2001 May 21;14(4):234-9.


CXCR4 and CCR5 expression by H9 T-cells is downregulated by a peptide-nucleic acid immunomodulator.

Lazzarino DA, Diego M, Musi E, Hirschman SZ, Alexander RJ.

Immunol Lett. 2000 Nov 1;74(3):189-95.


Yeast mitochondria contain ATP-sensitive, reversible actin-binding activity.

Lazzarino DA, Boldogh I, Smith MG, Rosand J, Pon LA.

Mol Biol Cell. 1994 Jul;5(7):807-18.


Deficient glycosylation of arylsulfatase A in pseudo arylsulfatase-A deficiency.

Ameen M, Lazzarino DA, Kelly BM, Gabel CA, Chang PL.

Mol Cell Biochem. 1990 Feb 9;92(2):117-27.


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