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Items: 36

1.

The Longest Amyloid-β Precursor Protein Intracellular Domain Produced with Aβ42 Forms β-Sheet-Containing Monomers That Self-Assemble and Are Proteolyzed by Insulin-Degrading Enzyme.

Krasinski CA, Zheng Q, Ivancic VA, Spratt DE, Lazo ND.

ACS Chem Neurosci. 2018 Aug 3. doi: 10.1021/acschemneuro.8b00305. [Epub ahead of print]

PMID:
30067897
2.

Mechanistic Studies of the Inhibition of Insulin Fibril Formation by Rosmarinic Acid.

Zheng Q, Lazo ND.

J Phys Chem B. 2018 Mar 1;122(8):2323-2331. doi: 10.1021/acs.jpcb.8b00689. Epub 2018 Feb 13.

PMID:
29401384
3.

A versatile platform for adding functional properties to amyloid fibrils.

Fontaine DFA, Ivancic VA, Reardon MB, Lazo ND, Jakobsche CE.

Org Biomol Chem. 2017 Oct 4;15(38):8023-8027. doi: 10.1039/c7ob02042b.

PMID:
28930349
4.

Binding Modes of Thioflavin T on the Surface of Amyloid Fibrils Studied by NMR.

Ivancic VA, Ekanayake O, Lazo ND.

Chemphyschem. 2016 Aug 18;17(16):2461-4. doi: 10.1002/cphc.201600246. Epub 2016 Jun 7.

PMID:
27165642
5.

Optimized bio-inspired stiffening design for an engine nacelle.

Lazo N, Vodenitcharova T, Hoffman M.

Bioinspir Biomim. 2015 Nov 4;10(6):066008. doi: 10.1088/1748-3190/10/6/066008.

PMID:
26531222
6.

K114 (trans, trans)-bromo-2,5-bis(4-hydroxystyryl)benzene is an efficient detector of cationic amyloid fibrils.

Selmani V, Robbins KJ, Ivancic VA, Lazo ND.

Protein Sci. 2015 Mar;24(3):420-5. doi: 10.1002/pro.2620. Epub 2015 Jan 13.

7.

Conformational analysis of thioflavin T bound to the surface of amyloid fibrils.

Robbins KJ, Liu G, Selmani V, Lazo ND.

Langmuir. 2012 Dec 4;28(48):16490-5. doi: 10.1021/la303677t. Epub 2012 Nov 16.

PMID:
23151310
8.

Kinetic profile of amyloid formation in the presence of an aromatic inhibitor by nuclear magnetic resonance.

Liu G, Gaines JC, Robbins KJ, Lazo ND.

ACS Med Chem Lett. 2012 Aug 28;3(10):856-9. doi: 10.1021/ml300147m. eCollection 2012 Oct 11.

9.

Curcumin modulates the self-assembly of the islet amyloid polypeptide by disassembling α-helix.

Sparks S, Liu G, Robbins KJ, Lazo ND.

Biochem Biophys Res Commun. 2012 Jun 15;422(4):551-5. doi: 10.1016/j.bbrc.2012.05.013. Epub 2012 May 10.

PMID:
22579683
10.

Helix-dipole effects in peptide self-assembly to amyloid.

Liu G, Robbins KJ, Sparks S, Selmani V, Bilides KM, Gomes EE, Lazo ND.

Biochemistry. 2012 May 22;51(20):4167-74. doi: 10.1021/bi3001616. Epub 2012 May 11.

PMID:
22559877
11.

Treatment of malignant, non-resectable, epithelial origin esophageal tumours with the humanized anti-epidermal growth factor antibody nimotuzumab combined with radiation therapy and chemotherapy.

Ramos-Suzarte M, Lorenzo-Luaces P, Lazo NG, Perez ML, Soriano JL, Gonzalez CE, Hernadez IM, Albuerne YÁ, Moreno BP, Alvarez ES, Callejo IP, Alert J, Martell JA, Gonzalez YS, Gonzalez YS, Astudillo de la Vega H, Ruiz-Garcia EB, Ramos TC.

Cancer Biol Ther. 2012 Jun;13(8):600-5. doi: 10.4161/cbt.19849. Epub 2012 Jun 1.

PMID:
22555809
12.

Mechanistic studies of peptide self-assembly: transient α-helices to stable β-sheets.

Liu G, Prabhakar A, Aucoin D, Simon M, Sparks S, Robbins KJ, Sheen A, Petty SA, Lazo ND.

J Am Chem Soc. 2010 Dec 29;132(51):18223-32. doi: 10.1021/ja1069882. Epub 2010 Dec 7.

PMID:
21138275
13.

Amyloid-β protein oligomerization and the importance of tetramers and dodecamers in the aetiology of Alzheimer's disease.

Bernstein SL, Dupuis NF, Lazo ND, Wyttenbach T, Condron MM, Bitan G, Teplow DB, Shea JE, Ruotolo BT, Robinson CV, Bowers MT.

Nat Chem. 2009 Jul;1(4):326-31. doi: 10.1038/nchem.247.

14.

Amyloid beta-protein: experiment and theory on the 21-30 fragment.

Murray MM, Krone MG, Bernstein SL, Baumketner A, Condron MM, Lazo ND, Teplow DB, Wyttenbach T, Shea JE, Bowers MT.

J Phys Chem B. 2009 Apr 30;113(17):6041-6. doi: 10.1021/jp808384x.

15.

Effects of familial Alzheimer's disease mutations on the folding nucleation of the amyloid beta-protein.

Krone MG, Baumketner A, Bernstein SL, Wyttenbach T, Lazo ND, Teplow DB, Bowers MT, Shea JE.

J Mol Biol. 2008 Aug 1;381(1):221-8. doi: 10.1016/j.jmb.2008.05.069. Epub 2008 Jun 4.

16.

Familial Alzheimer's disease mutations alter the stability of the amyloid beta-protein monomer folding nucleus.

Grant MA, Lazo ND, Lomakin A, Condron MM, Arai H, Yamin G, Rigby AC, Teplow DB.

Proc Natl Acad Sci U S A. 2007 Oct 16;104(42):16522-7. Epub 2007 Oct 10.

17.

Elucidating amyloid beta-protein folding and assembly: A multidisciplinary approach.

Teplow DB, Lazo ND, Bitan G, Bernstein S, Wyttenbach T, Bowers MT, Baumketner A, Shea JE, Urbanc B, Cruz L, Borreguero J, Stanley HE.

Acc Chem Res. 2006 Sep;39(9):635-45. Review.

18.

Structure of the 21-30 fragment of amyloid beta-protein.

Baumketner A, Bernstein SL, Wyttenbach T, Lazo ND, Teplow DB, Bowers MT, Shea JE.

Protein Sci. 2006 Jun;15(6):1239-47.

19.
20.

Solvent and mutation effects on the nucleation of amyloid beta-protein folding.

Cruz L, Urbanc B, Borreguero JM, Lazo ND, Teplow DB, Stanley HE.

Proc Natl Acad Sci U S A. 2005 Dec 20;102(51):18258-63. Epub 2005 Dec 9.

21.

On the nucleation of amyloid beta-protein monomer folding.

Lazo ND, Grant MA, Condron MC, Rigby AC, Teplow DB.

Protein Sci. 2005 Jun;14(6):1581-96.

22.

Folding events in the 21-30 region of amyloid beta-protein (Abeta) studied in silico.

Borreguero JM, Urbanc B, Lazo ND, Buldyrev SV, Teplow DB, Stanley HE.

Proc Natl Acad Sci U S A. 2005 Apr 26;102(17):6015-20. Epub 2005 Apr 18.

23.

EX1 hydrogen exchange and protein folding.

Ferraro DM, Lazo N, Robertson AD.

Biochemistry. 2004 Jan 27;43(3):587-94. Review. Erratum in: Biochemistry. 2004 Mar 30;43(12):3756.

PMID:
14730962
24.
26.
27.

Fibril formation by amyloid-beta proteins may involve beta-helical protofibrils.

Lazo ND, Downing DT.

J Pept Res. 1999 Jun;53(6):633-40.

PMID:
10408337
29.

Amyloid fibrils may be assembled from beta-helical protofibrils.

Lazo ND, Downing DT.

Biochemistry. 1998 Feb 17;37(7):1731-5. Review. No abstract available.

PMID:
9492738
30.

Beta-helical fibrils from a model peptide.

Lazo ND, Downing DT.

Biochem Biophys Res Commun. 1997 Jun 27;235(3):675-9.

PMID:
9207218
31.
32.
34.

Low-temperature solid-state 15N NMR characterization of polypeptide backbone librations.

Lazo ND, Hu W, Cross TA.

J Magn Reson B. 1995 Apr;107(1):43-50.

PMID:
7538014
35.

6-Hydroxy-4-sphingenine in human epidermal ceramides.

Robson KJ, Stewart ME, Michelsen S, Lazo ND, Downing DT.

J Lipid Res. 1994 Nov;35(11):2060-8.

36.

Rapidly-frozen polypeptide samples for characterization of high definition dynamics by solid-state NMR spectroscopy.

Lazo ND, Hu W, Lee KC, Cross TA.

Biochem Biophys Res Commun. 1993 Dec 15;197(2):904-9.

PMID:
7505577

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