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Items: 44

1.

Predicting Drug-Induced Liver Injury with Bayesian Machine Learning.

Williams DP, Lazic SE, Foster AJ, Semenova E, Morgan P.

Chem Res Toxicol. 2019 Oct 2. doi: 10.1021/acs.chemrestox.9b00264. [Epub ahead of print]

PMID:
31535850
2.

Conclusions from a behavioral aging study on male and female F2 hybrid mice on age-related behavior, buoyancy in water-based tests, and an ethical method to assess lifespan.

Adelöf J, Ross JM, Lazic SE, Zetterberg M, Wiseman J, Hernebring M.

Aging (Albany NY). 2019 Sep 11;11(17):7150-7168. doi: 10.18632/aging.102242. Epub 2019 Sep 11.

3.

Integrated in vitro models for hepatic safety and metabolism: evaluation of a human Liver-Chip and liver spheroid.

Foster AJ, Chouhan B, Regan SL, Rollison H, Amberntsson S, Andersson LC, Srivastava A, Darnell M, Cairns J, Lazic SE, Jang KJ, Petropolis DB, Kodella K, Rubins JE, Williams D, Hamilton GA, Ewart L, Morgan P.

Arch Toxicol. 2019 Apr;93(4):1021-1037. doi: 10.1007/s00204-019-02427-4. Epub 2019 Mar 26.

PMID:
30915487
4.

Training in experimental design and statistics is essential: Response to Jordan.

Lazic SE, Clarke-Williams CJ, Munafò MR.

PLoS Biol. 2018 Oct 15;16(10):e3000022. doi: 10.1371/journal.pbio.3000022. eCollection 2018 Oct.

5.

Four simple ways to increase power without increasing the sample size.

Lazic SE.

Lab Anim. 2018 Dec;52(6):621-629. doi: 10.1177/0023677218767478. Epub 2018 Apr 8.

PMID:
29629616
6.

What exactly is 'N' in cell culture and animal experiments?

Lazic SE, Clarke-Williams CJ, Munafò MR.

PLoS Biol. 2018 Apr 4;16(4):e2005282. doi: 10.1371/journal.pbio.2005282. eCollection 2018 Apr.

7.

Predicting Drug Safety and Communicating Risk: Benefits of a Bayesian Approach.

Lazic SE, Edmunds N, Pollard CE.

Toxicol Sci. 2018 Mar 1;162(1):89-98. doi: 10.1093/toxsci/kfx236.

PMID:
29126124
8.

An open-label study to assess the feasibility and tolerability of rilmenidine for the treatment of Huntington's disease.

Underwood BR, Green-Thompson ZW, Pugh PJ, Lazic SE, Mason SL, Griffin J, Jones PS, Rowe JB, Rubinsztein DC, Barker RA.

J Neurol. 2017 Dec;264(12):2457-2463. doi: 10.1007/s00415-017-8647-0. Epub 2017 Oct 26.

9.

An Analysis of the Relationship Between Preclinical and Clinical QT Interval-Related Data.

Pollard CE, Skinner M, Lazic SE, Prior HM, Conlon KM, Valentin JP, Dota C.

Toxicol Sci. 2017 Sep 1;159(1):94-101. doi: 10.1093/toxsci/kfx125.

PMID:
28903488
10.

A multi-scale convolutional neural network for phenotyping high-content cellular images.

Godinez WJ, Hossain I, Lazic SE, Davies JW, Zhang X.

Bioinformatics. 2017 Jul 1;33(13):2010-2019. doi: 10.1093/bioinformatics/btx069.

PMID:
28203779
11.

Ranking, selecting, and prioritising genes with desirability functions.

Lazic SE.

PeerJ. 2015 Nov 26;3:e1444. doi: 10.7717/peerj.1444. eCollection 2015.

12.

Large-scale phenotyping links adult hippocampal neurogenesis to the reaction to novelty.

van Dijk RM, Lazic SE, Slomianka L, Wolfer DP, Amrein I.

Hippocampus. 2016 May;26(5):646-57. doi: 10.1002/hipo.22548. Epub 2015 Nov 25.

PMID:
26540138
13.

Sleep deficits but no metabolic deficits in premanifest Huntington's disease.

Lazar AS, Panin F, Goodman AO, Lazic SE, Lazar ZI, Mason SL, Rogers L, Murgatroyd PR, Watson LP, Singh P, Borowsky B, Shneerson JM, Barker RA.

Ann Neurol. 2015 Oct;78(4):630-48. doi: 10.1002/ana.24495. Epub 2015 Aug 21.

14.
15.

Quantifying the behavioural relevance of hippocampal neurogenesis.

Lazic SE, Fuss J, Gass P.

PLoS One. 2014 Nov 26;9(11):e113855. doi: 10.1371/journal.pone.0113855. eCollection 2014. Review.

16.

Chronic early life stress alters developmental and adult neurogenesis and impairs cognitive function in mice.

Naninck EF, Hoeijmakers L, Kakava-Georgiadou N, Meesters A, Lazic SE, Lucassen PJ, Korosi A.

Hippocampus. 2015 Mar;25(3):309-28. doi: 10.1002/hipo.22374. Epub 2014 Oct 30.

PMID:
25269685
17.

Trio study and meta-analysis support the association of genetic variation at the serotonin transporter with early-onset obsessive-compulsive disorder.

Walitza S, Marinova Z, Grünblatt E, Lazic SE, Remschmidt H, Vloet TD, Wendland JR.

Neurosci Lett. 2014 Sep 19;580:100-3. doi: 10.1016/j.neulet.2014.07.038. Epub 2014 Aug 2.

18.

A retrospective analysis of hand tapping as a longitudinal marker of disease progression in Huntington's disease.

Collins LM, Lazic SE, Barker RA.

BMC Neurol. 2014 Feb 24;14:35. doi: 10.1186/1471-2377-14-35.

19.

The hippocampus of the eastern rock sengi: cytoarchitecture, markers of neuronal function, principal cell numbers, and adult neurogenesis.

Slomianka L, Drenth T, Cavegn N, Menges D, Lazic SE, Phalanndwa M, Chimimba CT, Amrein I.

Front Neuroanat. 2013 Oct 29;7:34. doi: 10.3389/fnana.2013.00034. eCollection 2013.

20.
21.

Improving basic and translational science by accounting for litter-to-litter variation in animal models.

Lazic SE, Essioux L.

BMC Neurosci. 2013 Mar 22;14:37. doi: 10.1186/1471-2202-14-37.

22.

A call for transparent reporting to optimize the predictive value of preclinical research.

Landis SC, Amara SG, Asadullah K, Austin CP, Blumenstein R, Bradley EW, Crystal RG, Darnell RB, Ferrante RJ, Fillit H, Finkelstein R, Fisher M, Gendelman HE, Golub RM, Goudreau JL, Gross RA, Gubitz AK, Hesterlee SE, Howells DW, Huguenard J, Kelner K, Koroshetz W, Krainc D, Lazic SE, Levine MS, Macleod MR, McCall JM, Moxley RT 3rd, Narasimhan K, Noble LJ, Perrin S, Porter JD, Steward O, Unger E, Utz U, Silberberg SD.

Nature. 2012 Oct 11;490(7419):187-91. doi: 10.1038/nature11556.

23.

Sustained hippocampal neurogenesis in females is amplified in P66(Shc-/-) mice: An animal model of healthy aging.

Berry A, Amrein I, Nötzli S, Lazic SE, Bellisario V, Giorgio M, Pelicci PG, Alleva E, Lipp HP, Cirulli F.

Hippocampus. 2012 Dec;22(12):2249-59. doi: 10.1002/hipo.22042. Epub 2012 Jun 18.

PMID:
22707391
24.

Transcriptional profiling of human brain endothelial cells reveals key properties crucial for predictive in vitro blood-brain barrier models.

Urich E, Lazic SE, Molnos J, Wells I, Freskgård PO.

PLoS One. 2012;7(5):e38149. doi: 10.1371/journal.pone.0038149. Epub 2012 May 31.

25.

Expression profiles of metabolic enzymes and drug transporters in the liver and along the intestine of beagle dogs.

Haller S, Schuler F, Lazic SE, Bachir-Cherif D, Krämer SD, Parrott NJ, Steiner G, Belli S.

Drug Metab Dispos. 2012 Aug;40(8):1603-10. doi: 10.1124/dmd.112.045443. Epub 2012 May 17.

PMID:
22596220
26.

Role of the intestinal peptide transporter PEPT1 in oseltamivir absorption: in vitro and in vivo studies.

Poirier A, Belli S, Funk C, Otteneder MB, Portmann R, Heinig K, Prinssen E, Lazic SE, Rayner CR, Hoffmann G, Singer T, Smith DE, Schuler F.

Drug Metab Dispos. 2012 Aug;40(8):1556-65. doi: 10.1124/dmd.112.044990. Epub 2012 May 14.

27.

Using causal models to distinguish between neurogenesis-dependent and -independent effects on behaviour.

Lazic SE.

J R Soc Interface. 2012 May 7;9(70):907-17. doi: 10.1098/rsif.2011.0510. Epub 2011 Sep 28.

28.

Modeling hippocampal neurogenesis across the lifespan in seven species.

Lazic SE.

Neurobiol Aging. 2012 Aug;33(8):1664-71. doi: 10.1016/j.neurobiolaging.2011.03.008. Epub 2011 May 28.

PMID:
21621300
29.

Common and overlapping oncogenic pathways contribute to the evolution of acute myeloid leukemias.

Kvinlaug BT, Chan WI, Bullinger L, Ramaswami M, Sears C, Foster D, Lazic SE, Okabe R, Benner A, Lee BH, De Silva I, Valk PJ, Delwel R, Armstrong SA, Döhner H, Gilliland DG, Huntly BJ.

Cancer Res. 2011 Jun 15;71(12):4117-29. doi: 10.1158/0008-5472.CAN-11-0176. Epub 2011 Apr 19.

30.

Relating hippocampal neurogenesis to behavior: the dangers of ignoring confounding variables.

Lazic SE.

Neurobiol Aging. 2010 Dec;31(12):2169-71; discussion 2172-5. doi: 10.1016/j.neurobiolaging.2010.04.037.

PMID:
20864221
31.

The problem of pseudoreplication in neuroscientific studies: is it affecting your analysis?

Lazic SE.

BMC Neurosci. 2010 Jan 14;11:5. doi: 10.1186/1471-2202-11-5.

32.

Visualising disease progression on multiple variables with vector plots and path plots.

Lazic SE, Mason SL, Michell AW, Barker RA.

BMC Med Res Methodol. 2009 May 27;9:32. doi: 10.1186/1471-2288-9-32.

33.

Graft outcomes influenced by co-expression of Pax7 in graft and host tissue.

Thomas M, Tyers P, Lazic SE, Caldwell MA, Barker RA, Beazley L, Ziman M.

J Anat. 2009 Mar;214(3):396-405. doi: 10.1111/j.1469-7580.2009.01049.x. Erratum in: J Anat. 2009 Aug;215(2):225. Caldwell, Maeve A [added].

34.
35.

Synergistic effects of dehydroepiandrosterone and fluoxetine on proliferation of progenitor cells in the dentate gyrus of the adult male rat.

Pinnock SB, Lazic SE, Wong HT, Wong IH, Herbert J.

Neuroscience. 2009 Feb 18;158(4):1644-51. doi: 10.1016/j.neuroscience.2008.10.035. Epub 2008 Oct 30.

36.
37.

Hand tapping: a simple, reproducible, objective marker of motor dysfunction in Huntington's disease.

Michell AW, Goodman AO, Silva AH, Lazic SE, Morton AJ, Barker RA.

J Neurol. 2008 Aug;255(8):1145-52. doi: 10.1007/s00415-008-0859-x. Epub 2008 May 13.

PMID:
18465109
38.
39.

Olfactory abnormalities in Huntington's disease: decreased plasticity in the primary olfactory cortex of R6/1 transgenic mice and reduced olfactory discrimination in patients.

Lazic SE, Goodman AO, Grote HE, Blakemore C, Morton AJ, Hannan AJ, van Dellen A, Barker RA.

Brain Res. 2007 Jun 2;1151:219-26. Epub 2007 Mar 12.

PMID:
17400200
40.

Lack of efficacy of music to improve sleep: a polysomnographic and quantitative EEG analysis.

Lazic SE, Ogilvie RD.

Int J Psychophysiol. 2007 Mar;63(3):232-9. Epub 2006 Nov 22.

PMID:
17123654
41.

Neurogenesis in the R6/1 transgenic mouse model of Huntington's disease: effects of environmental enrichment.

Lazic SE, Grote HE, Blakemore C, Hannan AJ, van Dellen A, Phillips W, Barker RA.

Eur J Neurosci. 2006 Apr;23(7):1829-38.

PMID:
16623840
42.

Rapid decline in motor symptoms in HD neural transplant patients prior to surgery.

Lazic SE, Barker RA.

Brain Res Bull. 2004 Mar 1;63(1):83-4. No abstract available.

PMID:
15121242
43.

Decreased hippocampal cell proliferation in R6/1 Huntington's mice.

Lazic SE, Grote H, Armstrong RJ, Blakemore C, Hannan AJ, van Dellen A, Barker RA.

Neuroreport. 2004 Apr 9;15(5):811-3.

PMID:
15073520
44.

The future of cell-based transplantation therapies for neurodegenerative disorders.

Lazic SE, Barker RA.

J Hematother Stem Cell Res. 2003 Dec;12(6):635-42. Review.

PMID:
14977473

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