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Items: 1 to 50 of 177

1.

cAMP Response Element-Binding Protein (CREB): A Possible Signaling Molecule Link in the Pathophysiology of Schizophrenia.

Wang H, Xu J, Lazarovici P, Quirion R, Zheng W.

Front Mol Neurosci. 2018 Aug 30;11:255. doi: 10.3389/fnmol.2018.00255. eCollection 2018. Review.

2.

Reverting the molecular fingerprint of tumor dormancy as a therapeutic strategy for glioblastoma.

Tiram G, Ferber S, Ofek P, Eldar-Boock A, Ben-Shushan D, Yeini E, Krivitsky A, Blatt R, Almog N, Henkin J, Amsalem O, Yavin E, Cohen G, Lazarovici P, Lee JS, Ruppin E, Milyavsky M, Grossman R, Ram Z, Calderón M, Haag R, Satchi-Fainaro R.

FASEB J. 2018 Jun 1:fj201701568R. doi: 10.1096/fj.201701568R. [Epub ahead of print]

PMID:
29856660
3.

Neuroprotective Effects of Bioactive Compounds and MAPK Pathway Modulation in "Ischemia"-Stressed PC12 Pheochromocytoma Cells.

Lahiani A, Brand-Yavin A, Yavin E, Lazarovici P.

Brain Sci. 2018 Feb 8;8(2). pii: E32. doi: 10.3390/brainsci8020032. Review.

4.

Nerve growth factor plays a role in the neurotherapeutic effect of a CD45+ pan-hematopoietic subpopulation derived from human umbilical cord blood in a traumatic brain injury model.

Gincberg G, Shohami E, Trembovler V, Alexandrovich AG, Lazarovici P, Elchalal U.

Cytotherapy. 2018 Feb;20(2):245-261. doi: 10.1016/j.jcyt.2017.11.008. Epub 2017 Dec 20.

PMID:
29274773
5.

Methylene-Cycloalkylacetate (MCA) Scaffold-Based Compounds as Novel Neurotropic Agents.

Lankri D, Haham D, Lahiani A, Lazarovici P, Tsvelikhovsky D.

ACS Chem Neurosci. 2018 Apr 18;9(4):691-698. doi: 10.1021/acschemneuro.7b00473. Epub 2017 Dec 29.

PMID:
29265805
6.
7.

Nerve Growth Factor-Induced Angiogenesis: 2. The Quail Chorioallantoic Membrane Assay.

Lazarovici P, Lahiani A, Gincberg G, Haham D, Marcinkiewicz C, Lelkes PI.

Methods Mol Biol. 2018;1727:251-259. doi: 10.1007/978-1-4939-7571-6_19.

PMID:
29222787
8.

Nerve Growth Factor-Induced Angiogenesis: 1. Endothelial Cell Tube Formation Assay.

Lazarovici P, Lahiani A, Gincberg G, Haham D, Fluksman A, Benny O, Marcinkiewicz C, Lelkes PI.

Methods Mol Biol. 2018;1727:239-250. doi: 10.1007/978-1-4939-7571-6_18.

PMID:
29222786
9.

Dysbindin-1 Involvement in the Etiology of Schizophrenia.

Wang H, Xu J, Lazarovici P, Zheng W.

Int J Mol Sci. 2017 Sep 22;18(10). pii: E2044. doi: 10.3390/ijms18102044. Review.

10.

The involvement of DARPP-32 in the pathophysiology of schizophrenia.

Wang H, Farhan M, Xu J, Lazarovici P, Zheng W.

Oncotarget. 2017 Apr 21;8(32):53791-53803. doi: 10.18632/oncotarget.17339. eCollection 2017 Aug 8. Review.

11.

The Molecular Basis of Toxins' Interactions with Intracellular Signaling via Discrete Portals.

Lahiani A, Yavin E, Lazarovici P.

Toxins (Basel). 2017 Mar 16;9(3). pii: E107. doi: 10.3390/toxins9030107. Review.

12.

Protein toxins of the Echis coloratus viper venom directly activate TRPV1.

Geron M, Kumar R, Matzner H, Lahiani A, Gincberg G, Cohen G, Lazarovici P, Priel A.

Biochim Biophys Acta Gen Subj. 2017 Mar;1861(3):615-623. doi: 10.1016/j.bbagen.2017.01.004. Epub 2017 Jan 4.

PMID:
28063984
13.

Novel Synthetic PEGylated Conjugate of α-Lipoic Acid and Tempol Reduces Cell Death in a Neuronal PC12 Clonal Line Subjected to Ischemia.

Lahiani A, Hidmi A, Katzhendler J, Yavin E, Lazarovici P.

ACS Chem Neurosci. 2016 Oct 19;7(10):1452-1462. Epub 2016 Aug 22.

PMID:
27499112
14.

Artemisinin conferred ERK mediated neuroprotection to PC12 cells and cortical neurons exposed to sodium nitroprusside-induced oxidative insult.

Zheng W, Chong CM, Wang H, Zhou X, Zhang L, Wang R, Meng Q, Lazarovici P, Fang J.

Free Radic Biol Med. 2016 Aug;97:158-167. doi: 10.1016/j.freeradbiomed.2016.05.023. Epub 2016 May 27.

PMID:
27242266
15.

Solid nano-in-nanoparticles for potential delivery of siRNA.

Amsalem O, Nassar T, Benhamron S, Lazarovici P, Benita S, Yavin E.

J Control Release. 2017 Jul 10;257:144-155. doi: 10.1016/j.jconrel.2016.05.043. Epub 2016 May 20.

PMID:
27215702
16.

Enhanced Re-Endothelialization of Decellularized Rat Lungs.

Stabler CT, Caires LC Jr, Mondrinos MJ, Marcinkiewicz C, Lazarovici P, Wolfson MR, Lelkes PI.

Tissue Eng Part C Methods. 2016 May;22(5):439-50. doi: 10.1089/ten.TEC.2016.0012. Epub 2016 Apr 1.

17.

Revascularization of decellularized lung scaffolds: principles and progress.

Stabler CT, Lecht S, Mondrinos MJ, Goulart E, Lazarovici P, Lelkes PI.

Am J Physiol Lung Cell Mol Physiol. 2015 Dec 1;309(11):L1273-85. doi: 10.1152/ajplung.00237.2015. Epub 2015 Sep 25. Review.

18.

Mesenchymal stem cells for therapeutic applications in pulmonary medicine.

Stabler CT, Lecht S, Lazarovici P, Lelkes PI.

Br Med Bull. 2015 Sep;115(1):45-56. doi: 10.1093/bmb/ldv026. Epub 2015 Jun 10. Review.

PMID:
26063231
19.

Enhanced therapeutic anti-inflammatory effect of betamethasone on topical administration with low-frequency, low-intensity (20 kHz, 100 mW/cm(2)) ultrasound exposure on carrageenan-induced arthritis in a mouse model.

Cohen G, Natsheh H, Sunny Y, Bawiec CR, Touitou E, Lerman MA, Lazarovici P, Lewin PA.

Ultrasound Med Biol. 2015 Sep;41(9):2449-57. doi: 10.1016/j.ultrasmedbio.2015.04.009. Epub 2015 May 21.

20.

Association of p75(NTR) and α9β1 integrin modulates NGF-dependent cellular responses.

Ventresca EM, Lecht S, Jakubowski P, Chiaverelli RA, Weaver M, Del Valle L, Ettinger K, Gincberg G, Priel A, Braiman A, Lazarovici P, Lelkes PI, Marcinkiewicz C.

Cell Signal. 2015 Jun;27(6):1225-36. doi: 10.1016/j.cellsig.2015.02.029. Epub 2015 Mar 5.

21.

Nerve growth factor-induced myoprotection in C2C12 muscle cells is mediated by α9β1 integrin via release of PGE2.

Ettinger K, Nevo Y, Marcinkiewicz C, Lazarovici P.

J Basic Clin Physiol Pharmacol. 2015 Jul;26(4):411-5. doi: 10.1515/jbcpp-2014-0111.

PMID:
25741790
22.

Anti-angiogenic activities of snake venom CRISP isolated from Echis carinatus sochureki.

Lecht S, Chiaverelli RA, Gerstenhaber J, Calvete JJ, Lazarovici P, Casewell NR, Harrison R, Lelkes PI, Marcinkiewicz C.

Biochim Biophys Acta. 2015 Jun;1850(6):1169-79. doi: 10.1016/j.bbagen.2015.02.002. Epub 2015 Feb 7.

PMID:
25665484
23.

Vipegitide: a folded peptidomimetic partial antagonist of α2β1 integrin with antiplatelet aggregation activity.

Momic T, Katzhendler J, Shai E, Noy E, Senderowitz H, Eble JA, Marcinkiewicz C, Varon D, Lazarovici P.

Drug Des Devel Ther. 2015 Jan 5;9:291-304. doi: 10.2147/DDDT.S72844. eCollection 2015.

24.

Gardenamide A attenuated cell apoptosis induced by serum deprivation insult via the ERK1/2 and PI3K/AKT signaling pathways.

Wang R, Yang J, Peng L, Zhao J, Mu N, Huang J, Lazarovici P, Chen H, Zheng W.

Neuroscience. 2015 Feb 12;286:242-50. doi: 10.1016/j.neuroscience.2014.11.056. Epub 2014 Dec 6.

PMID:
25485482
25.

Human placental eXpanded (PLX) mesenchymal-like adherent stromal cells confer neuroprotection to nerve growth factor (NGF)-differentiated PC12 cells exposed to ischemia by secretion of IL-6 and VEGF.

Lahiani A, Zahavi E, Netzer N, Ofir R, Pinzur L, Raveh S, Arien-Zakay H, Yavin E, Lazarovici P.

Biochim Biophys Acta. 2015 Feb;1853(2):422-30. doi: 10.1016/j.bbamcr.2014.11.009. Epub 2014 Nov 15.

26.

IGF-1 signaling via the PI3K/Akt pathway confers neuroprotection in human retinal pigment epithelial cells exposed to sodium nitroprusside insult.

Wang H, Liao S, Geng R, Zheng Y, Liao R, Yan F, Thrimawithana T, Little PJ, Feng ZP, Lazarovici P, Zheng W.

J Mol Neurosci. 2015 Apr;55(4):931-40. doi: 10.1007/s12031-014-0448-7. Epub 2014 Oct 23.

PMID:
25339505
27.

Transcriptional down-regulation of epidermal growth factor (EGF) receptors by nerve growth factor (NGF) in PC12 cells.

Cohen G, Ettinger K, Lecht S, Lelkes PI, Lazarovici P.

J Mol Neurosci. 2014 Nov;54(3):574-85. doi: 10.1007/s12031-014-0388-2. Epub 2014 Jul 31. Review.

PMID:
25078264
28.

Vimocin and vidapin, cyclic KTS peptides, are dual antagonists of α1β1/α2β1 integrins with antiangiogenic activity.

Momic T, Katzehendler J, Benny O, Lahiani A, Cohen G, Noy E, Senderowitz H, Eble JA, Marcinkiewicz C, Lazarovici P.

J Pharmacol Exp Ther. 2014 Sep;350(3):506-19. doi: 10.1124/jpet.114.214643. Epub 2014 Jun 17.

PMID:
24939421
29.

Neurotherapeutic effect of cord blood derived CD45+ hematopoietic cells in mice after traumatic brain injury.

Arien-Zakay H, Gincberg G, Nagler A, Cohen G, Liraz-Zaltsman S, Trembovler V, Alexandrovich AG, Matok I, Galski H, Elchalal U, Lelkes PI, Lazarovici P, Shohami E.

J Neurotrauma. 2014 Aug 15;31(16):1405-16. doi: 10.1089/neu.2013.3270. Epub 2014 Jul 14.

30.

Cytocompatibility of novel extracellular matrix protein analogs of biodegradable polyester polymers derived from α-hydroxy amino acids.

Lecht S, Cohen-Arazi N, Cohen G, Ettinger K, Momic T, Kolitz M, Naamneh M, Katzhendler J, Domb AJ, Lazarovici P, Lelkes PI.

J Biomater Sci Polym Ed. 2014;25(6):608-24. doi: 10.1080/09205063.2014.888303. Epub 2014 Feb 25.

PMID:
24568316
31.

The effects of a chactoid scorpion venom and its purified toxins on rat blood pressure and mast cells histamine release.

Ettinger K, Cohen G, Momic T, Lazarovici P.

Toxins (Basel). 2013 Jul 29;5(8):1332-42. doi: 10.3390/toxins5081332.

32.

Near infrared optical visualization of epidermal growth factor receptors levels in COLO205 colorectal cell line, orthotopic tumor in mice and human biopsies.

Cohen G, Lecht S, Oron-Herman M, Momic T, Nissan A, Lazarovici P.

Int J Mol Sci. 2013 Jul 12;14(7):14669-88. doi: 10.3390/ijms140714669.

33.

P-glycoprotein-dependent resistance of cancer cells toward the extrinsic TRAIL apoptosis signaling pathway.

Galski H, Oved-Gelber T, Simanovsky M, Lazarovici P, Gottesman MM, Nagler A.

Biochem Pharmacol. 2013 Sep 1;86(5):584-96. doi: 10.1016/j.bcp.2013.06.004. Epub 2013 Jun 14. Erratum in: Biochem Pharmacol. 2014 Dec 1;92(3):518.

34.

NGF promotes hemodynamic recovery in a rabbit hindlimb ischemic model through trkA- and VEGFR2-dependent pathways.

Karatzas A, Katsanos K, Lilis I, Papadaki H, Kitrou P, Lecht S, Marcinkiewicz C, Siablis D, Lelkes PI, Lazarovici P, Tsopanoglou NE.

J Cardiovasc Pharmacol. 2013 Sep;62(3):270-7. doi: 10.1097/FJC.0b013e3182982de7.

PMID:
23644989
35.

Tissue factor activity and ECM-related gene expression in human aortic endothelial cells grown on electrospun biohybrid scaffolds.

Han J, Gerstenhaber JA, Lazarovici P, Lelkes PI.

Biomacromolecules. 2013 May 13;14(5):1338-48. doi: 10.1021/bm400450m. Epub 2013 Apr 18.

PMID:
23560456
36.

Identification of inhibitors of α2β1 integrin, members of C-lectin type proteins, in Echis sochureki venom.

Jakubowski P, Calvete JJ, Eble JA, Lazarovici P, Marcinkiewicz C.

Toxicol Appl Pharmacol. 2013 May 15;269(1):34-42. doi: 10.1016/j.taap.2013.03.002. Epub 2013 Mar 13.

37.

Identification of α2β1 integrin inhibitor VP-i with anti-platelet properties in the venom of Vipera palaestinae.

Arlinghaus FT, Momic T, Ammar NA, Shai E, Spectre G, Varon D, Marcinkiewicz C, Heide H, Lazarovici P, Eble JA.

Toxicon. 2013 Mar 15;64:96-105. doi: 10.1016/j.toxicon.2013.01.001. Epub 2013 Jan 11.

PMID:
23319078
38.

Nerve growth factor reduces myocardial ischemia/reperfusion injury in rat hearts.

Strande JL, Routhu KV, Lecht S, Lazarovici P.

J Basic Clin Physiol Pharmacol. 2013;24(1):81-4. doi: 10.1515/jbcpp-2012-0045.

39.

Enhanced survival and neurite network formation of human umbilical cord blood neuronal progenitors in three-dimensional collagen constructs.

Bercu MM, Arien-Zakay H, Stoler D, Lecht S, Lelkes PI, Samuel S, Or R, Nagler A, Lazarovici P, Elchalal U.

J Mol Neurosci. 2013 Oct;51(2):249-61. doi: 10.1007/s12031-012-9933-z. Epub 2012 Dec 12.

PMID:
23233347
40.

Vixapatin (VP12), a c-type lectin-protein from Vipera xantina palestinae venom: characterization as a novel anti-angiogenic compound.

Momic T, Cohen G, Reich R, Arlinghaus FT, Eble JA, Marcinkiewicz C, Lazarovici P.

Toxins (Basel). 2012 Oct;4(10):862-77. doi: 10.3390/toxins4100862. Epub 2012 Oct 18.

41.

Bio-imaging of colorectal cancer models using near infrared labeled epidermal growth factor.

Cohen G, Lecht S, Arien-Zakay H, Ettinger K, Amsalem O, Oron-Herman M, Yavin E, Prus D, Benita S, Nissan A, Lazarovici P.

PLoS One. 2012;7(11):e48803. doi: 10.1371/journal.pone.0048803. Epub 2012 Nov 8.

42.

Electrospun hydroxyapatite-containing chitosan nanofibers crosslinked with genipin for bone tissue engineering.

Frohbergh ME, Katsman A, Botta GP, Lazarovici P, Schauer CL, Wegst UG, Lelkes PI.

Biomaterials. 2012 Dec;33(36):9167-78. doi: 10.1016/j.biomaterials.2012.09.009. Epub 2012 Sep 27.

43.

Neural stem cells: therapeutic potential for neurodegenerative diseases.

Gincberg G, Arien-Zakay H, Lazarovici P, Lelkes PI.

Br Med Bull. 2012;104:7-19. doi: 10.1093/bmb/lds024. Epub 2012 Sep 17. Review.

PMID:
22988303
44.

Nerve growth factor stimulation of ERK1/2 phosphorylation requires both p75NTR and α9β1 integrin and confers myoprotection towards ischemia in C2C12 skeletal muscle cell model.

Ettinger K, Lecht S, Arien-Zakay H, Cohen G, Aga-Mizrachi S, Yanay N, Saragovi HU, Nedev H, Marcinkiewicz C, Nevo Y, Lazarovici P.

Cell Signal. 2012 Dec;24(12):2378-88. doi: 10.1016/j.cellsig.2012.08.008. Epub 2012 Aug 30.

PMID:
22960610
45.

Angioneural crosstalk in scaffolds with oriented microchannels for regenerative spinal cord injury repair.

Saglam A, Perets A, Canver AC, Li HL, Kollins K, Cohen G, Fischer I, Lazarovici P, Lelkes PI.

J Mol Neurosci. 2013 Feb;49(2):334-46. doi: 10.1007/s12031-012-9863-9. Epub 2012 Aug 10.

PMID:
22878912
46.

Multimodal neuroprotection induced by PACAP38 in oxygen-glucose deprivation and middle cerebral artery occlusion stroke models.

Lazarovici P, Cohen G, Arien-Zakay H, Chen J, Zhang C, Chopp M, Jiang H.

J Mol Neurosci. 2012 Nov;48(3):526-40. Epub 2012 Jun 8.

47.

Neuroprotective effects of nimodipine and nifedipine in the NGF-differentiated PC12 cells exposed to oxygen-glucose deprivation or trophic withdrawal.

Lecht S, Rotfeld E, Arien-Zakay H, Tabakman R, Matzner H, Yaka R, Lelkes PI, Lazarovici P.

Int J Dev Neurosci. 2012 Oct;30(6):465-9. doi: 10.1016/j.ijdevneu.2012.05.007. Epub 2012 Jun 5.

PMID:
22677442
48.

Importance of interaction between nerve growth factor and α9β1 integrin in glial tumor angiogenesis.

Walsh EM, Kim R, Del Valle L, Weaver M, Sheffield J, Lazarovici P, Marcinkiewicz C.

Neuro Oncol. 2012 Jul;14(7):890-901. doi: 10.1093/neuonc/nos119. Epub 2012 May 17.

49.

Alimentary 'green' proteins as electrospun scaffolds for skin regenerative engineering.

Lin L, Perets A, Har-el YE, Varma D, Li M, Lazarovici P, Woerdeman DL, Lelkes PI.

J Tissue Eng Regen Med. 2013 Dec;7(12):994-1008. doi: 10.1002/term.1493. Epub 2012 Apr 12.

PMID:
22499248
50.

Biphasic influence of hypoxia on tuftelin expression in mouse mesenchymal C3H10T1/2 stem cells.

Deutsch D, Silverstein N, Shilo D, Lecht S, Lazarovici P, Blumenfeld A.

Eur J Oral Sci. 2011 Dec;119 Suppl 1:55-61. doi: 10.1111/j.1600-0722.2011.00861.x.

PMID:
22243227

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