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Items: 1 to 50 of 184

1.

Protective mechanism of artemisinin on rat bone marrow-derived mesenchymal stem cells against apoptosis induced by hydrogen peroxide via activation of c-Raf-Erk1/2-p90rsk-CREB pathway.

Fang J, Zhao X, Li S, Xing X, Wang H, Lazarovici P, Zheng W.

Stem Cell Res Ther. 2019 Oct 26;10(1):312. doi: 10.1186/s13287-019-1419-2.

2.

Measurements of Cell Death Induced by Snake and Spider's Venoms and Derived Toxins.

Maatuf Y, Priel A, Lazarovici P.

Methods Mol Biol. 2020;2068:239-268. doi: 10.1007/978-1-4939-9845-6_13.

PMID:
31576532
3.

Cell-Based Adhesion Assays for Isolation of Snake Venom's Integrin Antagonists.

Lazarovici P, Marcinkiewicz C, Lelkes PI.

Methods Mol Biol. 2020;2068:205-223. doi: 10.1007/978-1-4939-9845-6_11.

PMID:
31576530
4.

Snake- and Spider-Venom-Derived Toxins as Lead Compounds for Drug Development.

Lazarovici P.

Methods Mol Biol. 2020;2068:3-26. doi: 10.1007/978-1-4939-9845-6_1.

PMID:
31576520
5.

From Snake Venom's Disintegrins and C-Type Lectins to Anti-Platelet Drugs.

Lazarovici P, Marcinkiewicz C, Lelkes PI.

Toxins (Basel). 2019 May 27;11(5). pii: E303. doi: 10.3390/toxins11050303. Review.

6.

Anti-inflammatory Effects of Traditional Chinese Medicines on Preclinical in vivo Models of Brain Ischemia-Reperfusion-Injury: Prospects for Neuroprotective Drug Discovery and Therapy.

Peng T, Jiang Y, Farhan M, Lazarovici P, Chen L, Zheng W.

Front Pharmacol. 2019 Mar 7;10:204. doi: 10.3389/fphar.2019.00204. eCollection 2019. Review.

7.

Tuftelin Is Required for NGF-Induced Differentiation of PC12 Cells.

Shilo D, Cohen G, Blumenfeld A, Goren K, Hanhan S, Sharon S, Haze A, Deutsch D, Lazarovici P.

J Mol Neurosci. 2019 May;68(1):135-143. doi: 10.1007/s12031-019-01292-1. Epub 2019 Mar 21.

PMID:
30903486
8.

cAMP Response Element-Binding Protein (CREB): A Possible Signaling Molecule Link in the Pathophysiology of Schizophrenia.

Wang H, Xu J, Lazarovici P, Quirion R, Zheng W.

Front Mol Neurosci. 2018 Aug 30;11:255. doi: 10.3389/fnmol.2018.00255. eCollection 2018. Review.

9.

Reverting the molecular fingerprint of tumor dormancy as a therapeutic strategy for glioblastoma.

Tiram G, Ferber S, Ofek P, Eldar-Boock A, Ben-Shushan D, Yeini E, Krivitsky A, Blatt R, Almog N, Henkin J, Amsalem O, Yavin E, Cohen G, Lazarovici P, Lee JS, Ruppin E, Milyavsky M, Grossman R, Ram Z, Calderón M, Haag R, Satchi-Fainaro R.

FASEB J. 2018 Jun 1:fj201701568R. doi: 10.1096/fj.201701568R. [Epub ahead of print]

PMID:
29856660
10.

Neuroprotective Effects of Bioactive Compounds and MAPK Pathway Modulation in "Ischemia"-Stressed PC12 Pheochromocytoma Cells.

Lahiani A, Brand-Yavin A, Yavin E, Lazarovici P.

Brain Sci. 2018 Feb 8;8(2). pii: E32. doi: 10.3390/brainsci8020032. Review.

11.

Nerve growth factor plays a role in the neurotherapeutic effect of a CD45+ pan-hematopoietic subpopulation derived from human umbilical cord blood in a traumatic brain injury model.

Gincberg G, Shohami E, Trembovler V, Alexandrovich AG, Lazarovici P, Elchalal U.

Cytotherapy. 2018 Feb;20(2):245-261. doi: 10.1016/j.jcyt.2017.11.008. Epub 2017 Dec 20.

PMID:
29274773
12.

Methylene-Cycloalkylacetate (MCA) Scaffold-Based Compounds as Novel Neurotropic Agents.

Lankri D, Haham D, Lahiani A, Lazarovici P, Tsvelikhovsky D.

ACS Chem Neurosci. 2018 Apr 18;9(4):691-698. doi: 10.1021/acschemneuro.7b00473. Epub 2017 Dec 29.

PMID:
29265805
13.
14.

Nerve Growth Factor-Induced Angiogenesis: 2. The Quail Chorioallantoic Membrane Assay.

Lazarovici P, Lahiani A, Gincberg G, Haham D, Marcinkiewicz C, Lelkes PI.

Methods Mol Biol. 2018;1727:251-259. doi: 10.1007/978-1-4939-7571-6_19.

PMID:
29222787
15.

Nerve Growth Factor-Induced Angiogenesis: 1. Endothelial Cell Tube Formation Assay.

Lazarovici P, Lahiani A, Gincberg G, Haham D, Fluksman A, Benny O, Marcinkiewicz C, Lelkes PI.

Methods Mol Biol. 2018;1727:239-250. doi: 10.1007/978-1-4939-7571-6_18.

PMID:
29222786
16.

Dysbindin-1 Involvement in the Etiology of Schizophrenia.

Wang H, Xu J, Lazarovici P, Zheng W.

Int J Mol Sci. 2017 Sep 22;18(10). pii: E2044. doi: 10.3390/ijms18102044. Review.

17.

The involvement of DARPP-32 in the pathophysiology of schizophrenia.

Wang H, Farhan M, Xu J, Lazarovici P, Zheng W.

Oncotarget. 2017 Apr 21;8(32):53791-53803. doi: 10.18632/oncotarget.17339. eCollection 2017 Aug 8. Review.

18.

The Molecular Basis of Toxins' Interactions with Intracellular Signaling via Discrete Portals.

Lahiani A, Yavin E, Lazarovici P.

Toxins (Basel). 2017 Mar 16;9(3). pii: E107. doi: 10.3390/toxins9030107. Review.

19.

Protein toxins of the Echis coloratus viper venom directly activate TRPV1.

Geron M, Kumar R, Matzner H, Lahiani A, Gincberg G, Cohen G, Lazarovici P, Priel A.

Biochim Biophys Acta Gen Subj. 2017 Mar;1861(3):615-623. doi: 10.1016/j.bbagen.2017.01.004. Epub 2017 Jan 4.

PMID:
28063984
20.

Novel Synthetic PEGylated Conjugate of α-Lipoic Acid and Tempol Reduces Cell Death in a Neuronal PC12 Clonal Line Subjected to Ischemia.

Lahiani A, Hidmi A, Katzhendler J, Yavin E, Lazarovici P.

ACS Chem Neurosci. 2016 Oct 19;7(10):1452-1462. Epub 2016 Aug 22.

PMID:
27499112
21.

Artemisinin conferred ERK mediated neuroprotection to PC12 cells and cortical neurons exposed to sodium nitroprusside-induced oxidative insult.

Zheng W, Chong CM, Wang H, Zhou X, Zhang L, Wang R, Meng Q, Lazarovici P, Fang J.

Free Radic Biol Med. 2016 Aug;97:158-167. doi: 10.1016/j.freeradbiomed.2016.05.023. Epub 2016 May 27.

PMID:
27242266
22.

Solid nano-in-nanoparticles for potential delivery of siRNA.

Amsalem O, Nassar T, Benhamron S, Lazarovici P, Benita S, Yavin E.

J Control Release. 2017 Jul 10;257:144-155. doi: 10.1016/j.jconrel.2016.05.043. Epub 2016 May 20.

PMID:
27215702
23.

Enhanced Re-Endothelialization of Decellularized Rat Lungs.

Stabler CT, Caires LC Jr, Mondrinos MJ, Marcinkiewicz C, Lazarovici P, Wolfson MR, Lelkes PI.

Tissue Eng Part C Methods. 2016 May;22(5):439-50. doi: 10.1089/ten.TEC.2016.0012. Epub 2016 Apr 1.

24.

Revascularization of decellularized lung scaffolds: principles and progress.

Stabler CT, Lecht S, Mondrinos MJ, Goulart E, Lazarovici P, Lelkes PI.

Am J Physiol Lung Cell Mol Physiol. 2015 Dec 1;309(11):L1273-85. doi: 10.1152/ajplung.00237.2015. Epub 2015 Sep 25. Review.

25.

Mesenchymal stem cells for therapeutic applications in pulmonary medicine.

Stabler CT, Lecht S, Lazarovici P, Lelkes PI.

Br Med Bull. 2015 Sep;115(1):45-56. doi: 10.1093/bmb/ldv026. Epub 2015 Jun 10. Review.

PMID:
26063231
26.

Enhanced therapeutic anti-inflammatory effect of betamethasone on topical administration with low-frequency, low-intensity (20 kHz, 100 mW/cm(2)) ultrasound exposure on carrageenan-induced arthritis in a mouse model.

Cohen G, Natsheh H, Sunny Y, Bawiec CR, Touitou E, Lerman MA, Lazarovici P, Lewin PA.

Ultrasound Med Biol. 2015 Sep;41(9):2449-57. doi: 10.1016/j.ultrasmedbio.2015.04.009. Epub 2015 May 21.

27.

Association of p75(NTR) and α9β1 integrin modulates NGF-dependent cellular responses.

Ventresca EM, Lecht S, Jakubowski P, Chiaverelli RA, Weaver M, Del Valle L, Ettinger K, Gincberg G, Priel A, Braiman A, Lazarovici P, Lelkes PI, Marcinkiewicz C.

Cell Signal. 2015 Jun;27(6):1225-36. doi: 10.1016/j.cellsig.2015.02.029. Epub 2015 Mar 5.

28.

Nerve growth factor-induced myoprotection in C2C12 muscle cells is mediated by α9β1 integrin via release of PGE2.

Ettinger K, Nevo Y, Marcinkiewicz C, Lazarovici P.

J Basic Clin Physiol Pharmacol. 2015 Jul;26(4):411-5. doi: 10.1515/jbcpp-2014-0111.

PMID:
25741790
29.

Anti-angiogenic activities of snake venom CRISP isolated from Echis carinatus sochureki.

Lecht S, Chiaverelli RA, Gerstenhaber J, Calvete JJ, Lazarovici P, Casewell NR, Harrison R, Lelkes PI, Marcinkiewicz C.

Biochim Biophys Acta. 2015 Jun;1850(6):1169-79. doi: 10.1016/j.bbagen.2015.02.002. Epub 2015 Feb 7.

PMID:
25665484
30.

Vipegitide: a folded peptidomimetic partial antagonist of α2β1 integrin with antiplatelet aggregation activity.

Momic T, Katzhendler J, Shai E, Noy E, Senderowitz H, Eble JA, Marcinkiewicz C, Varon D, Lazarovici P.

Drug Des Devel Ther. 2015 Jan 5;9:291-304. doi: 10.2147/DDDT.S72844. eCollection 2015.

31.

Gardenamide A attenuated cell apoptosis induced by serum deprivation insult via the ERK1/2 and PI3K/AKT signaling pathways.

Wang R, Yang J, Peng L, Zhao J, Mu N, Huang J, Lazarovici P, Chen H, Zheng W.

Neuroscience. 2015 Feb 12;286:242-50. doi: 10.1016/j.neuroscience.2014.11.056. Epub 2014 Dec 6.

PMID:
25485482
32.

Human placental eXpanded (PLX) mesenchymal-like adherent stromal cells confer neuroprotection to nerve growth factor (NGF)-differentiated PC12 cells exposed to ischemia by secretion of IL-6 and VEGF.

Lahiani A, Zahavi E, Netzer N, Ofir R, Pinzur L, Raveh S, Arien-Zakay H, Yavin E, Lazarovici P.

Biochim Biophys Acta. 2015 Feb;1853(2):422-30. doi: 10.1016/j.bbamcr.2014.11.009. Epub 2014 Nov 15.

33.

IGF-1 signaling via the PI3K/Akt pathway confers neuroprotection in human retinal pigment epithelial cells exposed to sodium nitroprusside insult.

Wang H, Liao S, Geng R, Zheng Y, Liao R, Yan F, Thrimawithana T, Little PJ, Feng ZP, Lazarovici P, Zheng W.

J Mol Neurosci. 2015 Apr;55(4):931-40. doi: 10.1007/s12031-014-0448-7. Epub 2014 Oct 23.

PMID:
25339505
34.

Transcriptional down-regulation of epidermal growth factor (EGF) receptors by nerve growth factor (NGF) in PC12 cells.

Cohen G, Ettinger K, Lecht S, Lelkes PI, Lazarovici P.

J Mol Neurosci. 2014 Nov;54(3):574-85. doi: 10.1007/s12031-014-0388-2. Epub 2014 Jul 31. Review.

PMID:
25078264
35.

Vimocin and vidapin, cyclic KTS peptides, are dual antagonists of α1β1/α2β1 integrins with antiangiogenic activity.

Momic T, Katzehendler J, Benny O, Lahiani A, Cohen G, Noy E, Senderowitz H, Eble JA, Marcinkiewicz C, Lazarovici P.

J Pharmacol Exp Ther. 2014 Sep;350(3):506-19. doi: 10.1124/jpet.114.214643. Epub 2014 Jun 17.

PMID:
24939421
36.

Neurotherapeutic effect of cord blood derived CD45+ hematopoietic cells in mice after traumatic brain injury.

Arien-Zakay H, Gincberg G, Nagler A, Cohen G, Liraz-Zaltsman S, Trembovler V, Alexandrovich AG, Matok I, Galski H, Elchalal U, Lelkes PI, Lazarovici P, Shohami E.

J Neurotrauma. 2014 Aug 15;31(16):1405-16. doi: 10.1089/neu.2013.3270. Epub 2014 Jul 14.

37.

Cytocompatibility of novel extracellular matrix protein analogs of biodegradable polyester polymers derived from α-hydroxy amino acids.

Lecht S, Cohen-Arazi N, Cohen G, Ettinger K, Momic T, Kolitz M, Naamneh M, Katzhendler J, Domb AJ, Lazarovici P, Lelkes PI.

J Biomater Sci Polym Ed. 2014;25(6):608-24. doi: 10.1080/09205063.2014.888303. Epub 2014 Feb 25.

PMID:
24568316
38.

The effects of a chactoid scorpion venom and its purified toxins on rat blood pressure and mast cells histamine release.

Ettinger K, Cohen G, Momic T, Lazarovici P.

Toxins (Basel). 2013 Jul 29;5(8):1332-42. doi: 10.3390/toxins5081332.

39.

Near infrared optical visualization of epidermal growth factor receptors levels in COLO205 colorectal cell line, orthotopic tumor in mice and human biopsies.

Cohen G, Lecht S, Oron-Herman M, Momic T, Nissan A, Lazarovici P.

Int J Mol Sci. 2013 Jul 12;14(7):14669-88. doi: 10.3390/ijms140714669.

40.

P-glycoprotein-dependent resistance of cancer cells toward the extrinsic TRAIL apoptosis signaling pathway.

Galski H, Oved-Gelber T, Simanovsky M, Lazarovici P, Gottesman MM, Nagler A.

Biochem Pharmacol. 2013 Sep 1;86(5):584-96. doi: 10.1016/j.bcp.2013.06.004. Epub 2013 Jun 14. Erratum in: Biochem Pharmacol. 2014 Dec 1;92(3):518.

41.

NGF promotes hemodynamic recovery in a rabbit hindlimb ischemic model through trkA- and VEGFR2-dependent pathways.

Karatzas A, Katsanos K, Lilis I, Papadaki H, Kitrou P, Lecht S, Marcinkiewicz C, Siablis D, Lelkes PI, Lazarovici P, Tsopanoglou NE.

J Cardiovasc Pharmacol. 2013 Sep;62(3):270-7. doi: 10.1097/FJC.0b013e3182982de7.

PMID:
23644989
42.

Tissue factor activity and ECM-related gene expression in human aortic endothelial cells grown on electrospun biohybrid scaffolds.

Han J, Gerstenhaber JA, Lazarovici P, Lelkes PI.

Biomacromolecules. 2013 May 13;14(5):1338-48. doi: 10.1021/bm400450m. Epub 2013 Apr 18.

PMID:
23560456
43.

Identification of inhibitors of α2β1 integrin, members of C-lectin type proteins, in Echis sochureki venom.

Jakubowski P, Calvete JJ, Eble JA, Lazarovici P, Marcinkiewicz C.

Toxicol Appl Pharmacol. 2013 May 15;269(1):34-42. doi: 10.1016/j.taap.2013.03.002. Epub 2013 Mar 13.

44.

Identification of α2β1 integrin inhibitor VP-i with anti-platelet properties in the venom of Vipera palaestinae.

Arlinghaus FT, Momic T, Ammar NA, Shai E, Spectre G, Varon D, Marcinkiewicz C, Heide H, Lazarovici P, Eble JA.

Toxicon. 2013 Mar 15;64:96-105. doi: 10.1016/j.toxicon.2013.01.001. Epub 2013 Jan 11.

PMID:
23319078
45.

Nerve growth factor reduces myocardial ischemia/reperfusion injury in rat hearts.

Strande JL, Routhu KV, Lecht S, Lazarovici P.

J Basic Clin Physiol Pharmacol. 2013;24(1):81-4. doi: 10.1515/jbcpp-2012-0045.

46.

Enhanced survival and neurite network formation of human umbilical cord blood neuronal progenitors in three-dimensional collagen constructs.

Bercu MM, Arien-Zakay H, Stoler D, Lecht S, Lelkes PI, Samuel S, Or R, Nagler A, Lazarovici P, Elchalal U.

J Mol Neurosci. 2013 Oct;51(2):249-61. doi: 10.1007/s12031-012-9933-z. Epub 2012 Dec 12.

PMID:
23233347
47.

Vixapatin (VP12), a c-type lectin-protein from Vipera xantina palestinae venom: characterization as a novel anti-angiogenic compound.

Momic T, Cohen G, Reich R, Arlinghaus FT, Eble JA, Marcinkiewicz C, Lazarovici P.

Toxins (Basel). 2012 Oct;4(10):862-77. doi: 10.3390/toxins4100862. Epub 2012 Oct 18.

48.

Bio-imaging of colorectal cancer models using near infrared labeled epidermal growth factor.

Cohen G, Lecht S, Arien-Zakay H, Ettinger K, Amsalem O, Oron-Herman M, Yavin E, Prus D, Benita S, Nissan A, Lazarovici P.

PLoS One. 2012;7(11):e48803. doi: 10.1371/journal.pone.0048803. Epub 2012 Nov 8.

49.

Electrospun hydroxyapatite-containing chitosan nanofibers crosslinked with genipin for bone tissue engineering.

Frohbergh ME, Katsman A, Botta GP, Lazarovici P, Schauer CL, Wegst UG, Lelkes PI.

Biomaterials. 2012 Dec;33(36):9167-78. doi: 10.1016/j.biomaterials.2012.09.009. Epub 2012 Sep 27.

50.

Neural stem cells: therapeutic potential for neurodegenerative diseases.

Gincberg G, Arien-Zakay H, Lazarovici P, Lelkes PI.

Br Med Bull. 2012;104:7-19. doi: 10.1093/bmb/lds024. Epub 2012 Sep 17. Review.

PMID:
22988303

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