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Items: 30

1.

Mapping the Interface of a GPCR Dimer: A Structural Model of the A2A Adenosine and D2 Dopamine Receptor Heteromer.

Borroto-Escuela DO, Rodriguez D, Romero-Fernandez W, Kapla J, Jaiteh M, Ranganathan A, Lazarova T, Fuxe K, Carlsson J.

Front Pharmacol. 2018 Aug 30;9:829. doi: 10.3389/fphar.2018.00829. eCollection 2018.

2.

pH-sensitive vibrational probe reveals a cytoplasmic protonated cluster in bacteriorhodopsin.

Lorenz-Fonfria VA, Saita M, Lazarova T, Schlesinger R, Heberle J.

Proc Natl Acad Sci U S A. 2017 Dec 19;114(51):E10909-E10918. doi: 10.1073/pnas.1707993114. Epub 2017 Dec 4.

3.

Multiscale scenarios for nature futures.

Rosa IMD, Pereira HM, Ferrier S, Alkemade R, Acosta LA, Akcakaya HR, den Belder E, Fazel AM, Fujimori S, Harfoot M, Harhash KA, Harrison PA, Hauck J, Hendriks RJJ, Hernández G, Jetz W, Karlsson-Vinkhuyzen SI, Kim H, King N, Kok MTJ, Kolomytsev GO, Lazarova T, Leadley P, Lundquist CJ, García Márquez J, Meyer C, Navarro LM, Nesshöver C, Ngo HT, Ninan KN, Palomo MG, Pereira LM, Peterson GD, Pichs R, Popp A, Purvis A, Ravera F, Rondinini C, Sathyapalan J, Schipper AM, Seppelt R, Settele J, Sitas N, van Vuuren D.

Nat Ecol Evol. 2017 Oct;1(10):1416-1419. doi: 10.1038/s41559-017-0273-9. No abstract available.

PMID:
29185524
4.

Identification of Specific Effect of Chloride on the Spectral Properties and Structural Stability of Multiple Extracellular Glutamic Acid Mutants of Bacteriorhodopsin.

Lazarova T, Mlynarczyk K, Querol E, Tenchov B, Filipek S, Padrós E.

PLoS One. 2016 Sep 22;11(9):e0162952. doi: 10.1371/journal.pone.0162952. eCollection 2016.

5.

Effect of micronized cellulose powder on the efficacy of topical oxymetazoline in allergic rhinitis.

Valerieva A, Popov TA, Staevska M, Kralimarkova T, Petkova E, Valerieva E, Mustakov T, Lazarova T, Dimitrov V, Church MK.

Allergy Asthma Proc. 2015 Nov-Dec;36(6):e134-9. doi: 10.2500/aap.2015.36.3879. Epub 2015 Jun 29.

PMID:
26133030
6.

The effect of triple glutamic mutations E9Q/E194Q/E204Q on the structural stability of bacteriorhodopsin.

Lazarova T, Mlynarczyk K, Filipek S, Kolinski M, Wassenaar TA, Querol E, Renugopalakrishnan V, Viswanathan S, Padrós E.

FEBS J. 2014 Feb;281(4):1181-95. doi: 10.1111/febs.12694. Epub 2014 Jan 10.

7.

Real life clinical study design supporting the effectiveness of extra-fine inhaled beclomethasone/formoterol at the level of small airways of asthmatics.

Popov TA, Petrova D, Kralimarkova TZ, Ivanov Y, Popova T, Peneva M, Odzhakova T, Ilieva Y, Yakovliev P, Lazarova T, Georgiev O, Hodzhev V, Hodzheva E, Staevska MT, Dimitrov VD.

Pulm Pharmacol Ther. 2013 Dec;26(6):624-9. doi: 10.1016/j.pupt.2013.06.002. Epub 2013 Jun 14.

PMID:
23769863
8.

Identifying and measuring transmembrane helix-helix interactions by FRET.

Thévenin D, Lazarova T.

Methods Mol Biol. 2012;914:87-106. doi: 10.1007/978-1-62703-023-6_6.

PMID:
22976024
9.

Study of membrane-induced conformations of substance P: detection of extended polyproline II helix conformation.

Foroutan A, Lazarova T, Padrós E.

J Phys Chem B. 2011 Apr 7;115(13):3622-31. doi: 10.1021/jp1101253. Epub 2011 Mar 11.

PMID:
21395305
10.

Analysis of adenosine A₂a receptor stability: effects of ligands and disulfide bonds.

O'Malley MA, Naranjo AN, Lazarova T, Robinson AS.

Biochemistry. 2010 Nov 2;49(43):9181-9. doi: 10.1021/bi101155r.

11.

Cross-linking of transmembrane helices reveals a rigid-body mechanism in bacteriorhodopsin transport.

Simón-Vázquez R, Lazarova T, Perálvarez-Marín A, Bourdelande JL, Padrós E.

Angew Chem Int Ed Engl. 2009;48(45):8523-5. doi: 10.1002/anie.200904031. No abstract available.

PMID:
19810071
12.

Study on the feasibility of bacteriorhodopsin as bio-photosensitizer in excitonic solar cell: a first report.

Thavasi V, Lazarova T, Filipek S, Kolinski M, Querol E, Kumar A, Ramakrishna S, Padrós E, Renugopalakrishnan V.

J Nanosci Nanotechnol. 2009 Mar;9(3):1679-87.

PMID:
19435025
13.

Coupling between the retinal thermal isomerization and the Glu194 residue of bacteriorhodopsin.

Lazarova T, Querol E, Padrós E.

Photochem Photobiol. 2009 Mar-Apr;85(2):617-23. doi: 10.1111/j.1751-1097.2008.00534.x.

PMID:
19267876
14.

Stable interactions between the transmembrane domains of the adenosine A2A receptor.

Thévenin D, Lazarova T.

Protein Sci. 2008 Jul;17(7):1188-99. doi: 10.1110/ps.034843.108. Epub 2008 Apr 23.

15.

High-level expression in Saccharomyces cerevisiae enables isolation and spectroscopic characterization of functional human adenosine A2a receptor.

O'Malley MA, Lazarova T, Britton ZT, Robinson AS.

J Struct Biol. 2007 Aug;159(2):166-78. Epub 2007 May 16.

16.

Synthesis and in vitro biological evaluation of aryl boronic acids as potential inhibitors of factor XIa.

Lazarova TI, Jin L, Rynkiewicz M, Gorga JC, Bibbins F, Meyers HV, Babine R, Strickler J.

Bioorg Med Chem Lett. 2006 Oct 1;16(19):5022-7. Epub 2006 Jul 28.

PMID:
16876411
17.

Synthesis, SAR exploration, and X-ray crystal structures of factor XIa inhibitors containing an alpha-ketothiazole arginine.

Deng H, Bannister TD, Jin L, Babine RE, Quinn J, Nagafuji P, Celatka CA, Lin J, Lazarova TI, Rynkiewicz MJ, Bibbins F, Pandey P, Gorga J, Meyers HV, Abdel-Meguid SS, Strickler JE.

Bioorg Med Chem Lett. 2006 Jun 1;16(11):3049-54. Epub 2006 Mar 9.

PMID:
16524727
18.

Identifying interactions between transmembrane helices from the adenosine A2A receptor.

Thévenin D, Roberts MF, Lazarova T, Robinson CR.

Biochemistry. 2005 Dec 13;44(49):16239-45.

PMID:
16331984
19.

Synthesis of N-heteroaryl retinals and their artificial bacteriorhodopsins.

López S, Rodríguez V, Montenegro J, Saá C, Alvarez R, Silva López C, de Lera AR, Simón R, Lazarova T, Padrós E.

Chembiochem. 2005 Nov;6(11):2078-87.

PMID:
16231392
20.

Oligomerization of the fifth transmembrane domain from the adenosine A2A receptor.

Thévenin D, Lazarova T, Roberts MF, Robinson CR.

Protein Sci. 2005 Aug;14(8):2177-86. Epub 2005 Jun 29.

21.

Characterization of peptides corresponding to the seven transmembrane domains of human adenosine A2a receptor.

Lazarova T, Brewin KA, Stoeber K, Robinson CR.

Biochemistry. 2004 Oct 12;43(40):12945-54.

PMID:
15461468
22.

Synthesis and biological evaluation of novel cyclosporin a analogues: potential soft drugs for the treatment of autoimmune diseases.

Lazarova T, Chen JS, Hamann B, Kang JM, Homuth-Trombino D, Han F, Hoffmann E, McClure C, Eckstein J, Or YS.

J Med Chem. 2003 Feb 27;46(5):674-6.

PMID:
12593646
23.

Synthesis of new 14-membered macrolide antibiotics via a novel ring contraction metathesis.

Lazarova TI, Binet SM, Vo NH, Chen JS, Phan LT, Or YS.

Org Lett. 2003 Feb 20;5(4):443-5.

PMID:
12583739
24.

Specific effects of chloride on the photocycle of E194Q and E204Q mutants of bacteriorhodopsin as measured by FTIR spectroscopy.

Lazarova T, Sanz C, Sepulcre F, Querol E, Padrós E.

Biochemistry. 2002 Jun 25;41(25):8176-83.

PMID:
12069610
25.

New Efficient Method for the Total Synthesis of (S,S)-Isodityrosine from Natural Amino Acids.

Jung ME, Lazarova TI.

J Org Chem. 1999 Apr 30;64(9):2976-2977. No abstract available.

PMID:
11674381
26.

Contribution of extracellular Glu residues to the structure and function of bacteriorhodopsin. Presence of specific cation-binding sites.

Sanz C, Márquez M, Perálvarez A, Elouatik S, Sepulcre F, Querol E, Lazarova T, Padrós E.

J Biol Chem. 2001 Nov 2;276(44):40788-94. Epub 2001 Aug 27.

27.

Bacteriorhodopsin thermal stability: influence of bound cations and lipids on the intrinsic protein fluorescence.

Tuparev N, Dobrikova A, Taneva S, Lazarova T.

Z Naturforsch C. 2000 May-Jun;55(5-6):355-60.

PMID:
10928546
29.

Opening the Schiff base moiety of bacteriorhodopsin by mutation of the four extracellular Glu side chains.

Sanz C, Lazarova T, Sepulcre F, González-Moreno R, Bourdelande JL, Querol E, Padrós E.

FEBS Lett. 1999 Jul 30;456(1):191-5.

30.

Helical and reverse turn changes in the BR->N transition of bacteriorhodopsin.

Lazarova T, Padrós E.

Biochemistry. 1996 Jun 25;35(25):8354-8.

PMID:
8679593

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