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Items: 38

1.

YoungMito 2018: Report on the 1st International Mitochondria Meeting for Young Scientists.

Yamano K, Lazarou M.

Genes Cells. 2018 Oct;23(10):822-827. doi: 10.1111/gtc.12638. Epub 2018 Oct 1.

PMID:
30273445
2.

Ablation of tau causes an olfactory deficit in a murine model of Parkinson's disease.

Beauchamp LC, Chan J, Hung LW, Padman BS, Vella LJ, Liu XM, Coleman B, Bush AI, Lazarou M, Hill AF, Jacobson L, Barnham KJ.

Acta Neuropathol Commun. 2018 Jul 5;6(1):57. doi: 10.1186/s40478-018-0560-y.

3.

BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis.

McArthur K, Whitehead LW, Heddleston JM, Li L, Padman BS, Oorschot V, Geoghegan ND, Chappaz S, Davidson S, San Chin H, Lane RM, Dramicanin M, Saunders TL, Sugiana C, Lessene R, Osellame LD, Chew TL, Dewson G, Lazarou M, Ramm G, Lessene G, Ryan MT, Rogers KL, van Delft MF, Kile BT.

Science. 2018 Feb 23;359(6378). pii: eaao6047. doi: 10.1126/science.aao6047.

PMID:
29472455
4.

Correction for Nguyen et al., "Bacteriophage Transcytosis Provides a Mechanism To Cross Epithelial Cell Layers".

Nguyen S, Baker K, Padman BS, Patwa R, Dunstan RA, Weston TA, Schlosser K, Bailey B, Lithgow T, Lazarou M, Luque A, Rohwer F, Blumberg RS, Barr JJ.

MBio. 2018 Jan 2;9(1). pii: e02207-17. doi: 10.1128/mBio.02207-17. No abstract available.

5.

Autophagy induced during apoptosis degrades mitochondria and inhibits type I interferon secretion.

Lindqvist LM, Frank D, McArthur K, Dite TA, Lazarou M, Oakhill JS, Kile BT, Vaux DL.

Cell Death Differ. 2018 Mar;25(4):782-794. doi: 10.1038/s41418-017-0017-z. Epub 2017 Dec 11.

PMID:
29229994
6.

Bacteriophage Transcytosis Provides a Mechanism To Cross Epithelial Cell Layers.

Nguyen S, Baker K, Padman BS, Patwa R, Dunstan RA, Weston TA, Schlosser K, Bailey B, Lithgow T, Lazarou M, Luque A, Rohwer F, Blumberg RS, Barr JJ.

MBio. 2017 Nov 21;8(6). pii: e01874-17. doi: 10.1128/mBio.01874-17. Erratum in: MBio. 2018 Jan 2;9(1):.

7.

Defining sepsis on the wards: results of a multi-centre point-prevalence study comparing two sepsis definitions.

Szakmany T, Pugh R, Kopczynska M, Lundin RM, Sharif B, Morgan P, Ellis G, Abreu J, Kulikouskaya S, Bashir K, Galloway L, Al-Hassan H, Grother T, McNulty P, Seal ST, Cains A, Vreugdenhil M, Abdimalik M, Dennehey N, Evans G, Whitaker J, Beasant E, Hall C, Lazarou M, Vanderpump CV, Harding K, Duffy L, Guerrier Sadler A, Keeling R, Banks C, Ng SWY, Heng SY, Thomas D, Puw EW, Otahal I, Battle C, Minik O, Lyons RA, Hall JE; Welsh Digital Data Collection Platform collaborators.

Anaesthesia. 2018 Feb;73(2):195-204. doi: 10.1111/anae.14062. Epub 2017 Nov 17.

PMID:
29150856
8.

Structure, function, and regulation of mitofusin-2 in health and disease.

Chandhok G, Lazarou M, Neumann B.

Biol Rev Camb Philos Soc. 2018 May;93(2):933-949. doi: 10.1111/brv.12378. Epub 2017 Oct 25.

PMID:
29068134
9.

Autophagosome formation and cargo sequestration in the absence of LC3/GABARAPs.

Padman BS, Nguyen TN, Lazarou M.

Autophagy. 2017 Apr 3;13(4):772-774. doi: 10.1080/15548627.2017.1281492. Epub 2017 Feb 6.

10.

A fresh look at IBS-opportunities for systems medicine approaches.

Albusoda A, Barki N, Herregods T, Kamphuis JB, Karunaratne TB, Lazarou M, Lee I, Mazurak N, Perna E, Polster A, Pribic T, Uhlig F, Wang H, Enck P.

Neurogastroenterol Motil. 2017 Mar;29(3). doi: 10.1111/nmo.12989. Epub 2016 Nov 7. Review.

PMID:
27997070
11.

Atg8 family LC3/GABARAP proteins are crucial for autophagosome-lysosome fusion but not autophagosome formation during PINK1/Parkin mitophagy and starvation.

Nguyen TN, Padman BS, Usher J, Oorschot V, Ramm G, Lazarou M.

J Cell Biol. 2016 Dec 19;215(6):857-874. Epub 2016 Nov 18.

12.

The porin VDAC2 is the mitochondrial platform for Bax retrotranslocation.

Lauterwasser J, Todt F, Zerbes RM, Nguyen TN, Craigen W, Lazarou M, van der Laan M, Edlich F.

Sci Rep. 2016 Sep 13;6:32994. doi: 10.1038/srep32994.

13.

Parkin and mitophagy in cancer.

Bernardini JP, Lazarou M, Dewson G.

Oncogene. 2017 Mar;36(10):1315-1327. doi: 10.1038/onc.2016.302. Epub 2016 Sep 5. Review.

PMID:
27593930
14.

Deciphering the Molecular Signals of PINK1/Parkin Mitophagy.

Nguyen TN, Padman BS, Lazarou M.

Trends Cell Biol. 2016 Oct;26(10):733-744. doi: 10.1016/j.tcb.2016.05.008. Epub 2016 Jun 10. Review.

PMID:
27291334
15.

The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy.

Lazarou M, Sliter DA, Kane LA, Sarraf SA, Wang C, Burman JL, Sideris DP, Fogel AI, Youle RJ.

Nature. 2015 Aug 20;524(7565):309-314. doi: 10.1038/nature14893. Epub 2015 Aug 12.

16.

Keeping the immune system in check: a role for mitophagy.

Lazarou M.

Immunol Cell Biol. 2015 Jan;93(1):3-10. doi: 10.1038/icb.2014.75. Epub 2014 Sep 30. Review.

PMID:
25267485
17.

PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity.

Kane LA, Lazarou M, Fogel AI, Li Y, Yamano K, Sarraf SA, Banerjee S, Youle RJ.

J Cell Biol. 2014 Apr 28;205(2):143-53. doi: 10.1083/jcb.201402104. Epub 2014 Apr 21.

18.

Fetal calcium regulates branching morphogenesis in the developing human and mouse lung: involvement of voltage-gated calcium channels.

Brennan SC, Finney BA, Lazarou M, Rosser AE, Scherf C, Adriaensen D, Kemp PJ, Riccardi D.

PLoS One. 2013 Nov 25;8(11):e80294. doi: 10.1371/journal.pone.0080294. eCollection 2013.

19.

Assembly of the Bak apoptotic pore: a critical role for the Bak protein α6 helix in the multimerization of homodimers during apoptosis.

Ma S, Hockings C, Anwari K, Kratina T, Fennell S, Lazarou M, Ryan MT, Kluck RM, Dewson G.

J Biol Chem. 2013 Sep 6;288(36):26027-38. doi: 10.1074/jbc.M113.490094. Epub 2013 Jul 26.

20.

Sequestration and autophagy of mitochondria do not cut proteins across the board.

Huang CH, Lazarou M, Youle RJ.

Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6252-3. doi: 10.1073/pnas.1303921110. Epub 2013 Apr 8. No abstract available.

21.

PINK1 drives Parkin self-association and HECT-like E3 activity upstream of mitochondrial binding.

Lazarou M, Narendra DP, Jin SM, Tekle E, Banerjee S, Youle RJ.

J Cell Biol. 2013 Jan 21;200(2):163-72. doi: 10.1083/jcb.201210111. Epub 2013 Jan 14.

22.

Tissue-specific splicing of an Ndufs6 gene-trap insertion generates a mitochondrial complex I deficiency-specific cardiomyopathy.

Ke BX, Pepe S, Grubb DR, Komen JC, Laskowski A, Rodda FA, Hardman BM, Pitt JJ, Ryan MT, Lazarou M, Koleff J, Cheung MM, Smolich JJ, Thorburn DR.

Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):6165-70. doi: 10.1073/pnas.1113987109. Epub 2012 Apr 2.

23.

Role of PINK1 binding to the TOM complex and alternate intracellular membranes in recruitment and activation of the E3 ligase Parkin.

Lazarou M, Jin SM, Kane LA, Youle RJ.

Dev Cell. 2012 Feb 14;22(2):320-33. doi: 10.1016/j.devcel.2011.12.014. Epub 2012 Jan 25.

24.

Mutations in the gene encoding C8orf38 block complex I assembly by inhibiting production of the mitochondria-encoded subunit ND1.

McKenzie M, Tucker EJ, Compton AG, Lazarou M, George C, Thorburn DR, Ryan MT.

J Mol Biol. 2011 Dec 2;414(3):413-26. doi: 10.1016/j.jmb.2011.10.012. Epub 2011 Oct 14.

PMID:
22019594
25.

Native-state stability determines the extent of degradation relative to secretion of protein variants from Pichia pastoris.

Whyteside G, Alcocer MJ, Kumita JR, Dobson CM, Lazarou M, Pleass RJ, Archer DB.

PLoS One. 2011;6(7):e22692. doi: 10.1371/journal.pone.0022692. Epub 2011 Jul 27.

26.

Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL.

Jin SM, Lazarou M, Wang C, Kane LA, Narendra DP, Youle RJ.

J Cell Biol. 2010 Nov 29;191(5):933-42. doi: 10.1083/jcb.201008084.

27.

Inhibition of Bak activation by VDAC2 is dependent on the Bak transmembrane anchor.

Lazarou M, Stojanovski D, Frazier AE, Kotevski A, Dewson G, Craigen WJ, Kluck RM, Vaux DL, Ryan MT.

J Biol Chem. 2010 Nov 19;285(47):36876-83. doi: 10.1074/jbc.M110.159301. Epub 2010 Sep 17.

28.

Cost of a naturally occurring two-amino acid deletion in cytochrome c oxidase subunit 7A in Drosophila simulans.

Ballard JW, Melvin RG, Lazarou M, Clissold FJ, Simpson SJ.

Am Nat. 2010 Oct;176(4):E98-E108. doi: 10.1086/656263.

PMID:
20698788
29.

Assembly of nuclear DNA-encoded subunits into mitochondrial complex IV, and their preferential integration into supercomplex forms in patient mitochondria.

Lazarou M, Smith SM, Thorburn DR, Ryan MT, McKenzie M.

FEBS J. 2009 Nov;276(22):6701-13. doi: 10.1111/j.1742-4658.2009.07384.x. Epub 2009 Oct 16.

30.

Inhibition of erythrocyte invasion and Plasmodium falciparum merozoite surface protein 1 processing by human immunoglobulin G1 (IgG1) and IgG3 antibodies.

Lazarou M, Guevara Patiño JA, Jennings RM, McIntosh RS, Shi J, Howell S, Cullen E, Jones T, Adame-Gallegos JR, Chappel JA, McBride JS, Blackman MJ, Holder AA, Pleass RJ.

Infect Immun. 2009 Dec;77(12):5659-67. doi: 10.1128/IAI.00167-09. Epub 2009 Oct 5.

31.

Chapter 18 Analysis of respiratory chain complex assembly with radiolabeled nuclear- and mitochondrial-encoded subunits.

McKenzie M, Lazarou M, Ryan MT.

Methods Enzymol. 2009;456:321-39. doi: 10.1016/S0076-6879(08)04418-2.

PMID:
19348897
32.

Assembly of mitochondrial complex I and defects in disease.

Lazarou M, Thorburn DR, Ryan MT, McKenzie M.

Biochim Biophys Acta. 2009 Jan;1793(1):78-88. doi: 10.1016/j.bbamcr.2008.04.015. Epub 2008 May 4. Review.

33.

Human CIA30 is involved in the early assembly of mitochondrial complex I and mutations in its gene cause disease.

Dunning CJ, McKenzie M, Sugiana C, Lazarou M, Silke J, Connelly A, Fletcher JM, Kirby DM, Thorburn DR, Ryan MT.

EMBO J. 2007 Jul 11;26(13):3227-37. Epub 2007 Jun 7.

34.

The importance of human FcgammaRI in mediating protection to malaria.

McIntosh RS, Shi J, Jennings RM, Chappel JC, de Koning-Ward TF, Smith T, Green J, van Egmond M, Leusen JH, Lazarou M, van de Winkel J, Jones TS, Crabb BS, Holder AA, Pleass RJ.

PLoS Pathog. 2007 May 18;3(5):e72.

35.

Analysis of the assembly profiles for mitochondrial- and nuclear-DNA-encoded subunits into complex I.

Lazarou M, McKenzie M, Ohtake A, Thorburn DR, Ryan MT.

Mol Cell Biol. 2007 Jun;27(12):4228-37. Epub 2007 Apr 16.

36.

Analysis of mitochondrial subunit assembly into respiratory chain complexes using Blue Native polyacrylamide gel electrophoresis.

McKenzie M, Lazarou M, Thorburn DR, Ryan MT.

Anal Biochem. 2007 May 15;364(2):128-37. Epub 2007 Feb 24.

PMID:
17391635
37.

Mitochondrial respiratory chain supercomplexes are destabilized in Barth Syndrome patients.

McKenzie M, Lazarou M, Thorburn DR, Ryan MT.

J Mol Biol. 2006 Aug 18;361(3):462-9. Epub 2006 Jul 5.

PMID:
16857210
38.

Crystal structure of the mitochondrial chaperone TIM9.10 reveals a six-bladed alpha-propeller.

Webb CT, Gorman MA, Lazarou M, Ryan MT, Gulbis JM.

Mol Cell. 2006 Jan 6;21(1):123-33.

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