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Items: 1 to 50 of 284

1.

Aspects of Gut Microbiota and Immune System Interactions in Infectious Diseases, Immunopathology, and Cancer.

Lazar V, Ditu LM, Pircalabioru GG, Gheorghe I, Curutiu C, Holban AM, Picu A, Petcu L, Chifiriuc MC.

Front Immunol. 2018 Aug 15;9:1830. doi: 10.3389/fimmu.2018.01830. eCollection 2018. Review.

2.

Bioactive Natural Products 2018.

Kourkoutas Y, Chorianopoulos N, Lazar V, Di Ciccio P.

Biomed Res Int. 2018 May 27;2018:5063437. doi: 10.1155/2018/5063437. eCollection 2018. No abstract available.

3.

Antibiotic-resistant bacteria show widespread collateral sensitivity to antimicrobial peptides.

Lázár V, Martins A, Spohn R, Daruka L, Grézal G, Fekete G, Számel M, Jangir PK, Kintses B, Csörgő B, Nyerges Á, Györkei Á, Kincses A, Dér A, Walter FR, Deli MA, Urbán E, Hegedűs Z, Olajos G, Méhi O, Bálint B, Nagy I, Martinek TA, Papp B, Pál C.

Nat Microbiol. 2018 Jun;3(6):718-731. doi: 10.1038/s41564-018-0164-0. Epub 2018 May 24.

PMID:
29795541
4.

Genetic alterations in sporadic triple negative breast cancer.

Pop LA, Cojocneanu-Petric RM, Pileczki V, Morar-Bolba G, Irimie A, Lazar V, Lombardo C, Paradiso A, Berindan-Neagoe I.

Breast. 2018 Apr;38:30-38. doi: 10.1016/j.breast.2017.11.006. Epub 2017 Dec 5.

PMID:
29202330
5.

Development and Biocompatibility Evaluation of Photocatalytic TiO₂/Reduced Graphene Oxide-Based Nanoparticles Designed for Self-Cleaning Purposes.

Nica IC, Stan MS, Popa M, Chifiriuc MC, Pircalabioru GG, Lazar V, Dumitrescu I, Diamandescu L, Feder M, Baibarac M, Cernea M, Maraloiu VA, Popescu T, Dinischiotu A.

Nanomaterials (Basel). 2017 Sep 19;7(9). pii: E279. doi: 10.3390/nano7090279.

6.

Photocatalytic, Antimicrobial and Biocompatibility Features of Cotton Knit Coated with Fe-N-Doped Titanium Dioxide Nanoparticles.

Stan MS, Nica IC, Dinischiotu A, Varzaru E, Iordache OG, Dumitrescu I, Popa M, Chifiriuc MC, Pircalabioru GG, Lazar V, Bezirtzoglou E, Feder M, Diamandescu L.

Materials (Basel). 2016 Sep 21;9(9). pii: E789. doi: 10.3390/ma9090789.

7.

Correction: Phenotypic heterogeneity promotes adaptive evolution.

Bódi Z, Farkas Z, Nevozhay D, Kalapis D, Lázár V, Csörgő B, Nyerges Á, Szamecz B, Fekete G, Papp B, Araújo H, Oliveira JL, Moura G, Santos MAS, Székely T Jr, Balázsi G, Pál C.

PLoS Biol. 2017 Jun 20;15(6):e1002607. doi: 10.1371/journal.pbio.1002607. eCollection 2017 Jun.

8.

Antibiotic Resistance and Virulence Phenotypes of Recent Bacterial Strains Isolated from Urinary Tract Infections in Elderly Patients with Prostatic Disease.

Delcaru C, Podgoreanu P, Alexandru I, Popescu N, Măruţescu L, Bleotu C, Mogoşanu GD, Chifiriuc MC, Gluck M, Lazăr V.

Pathogens. 2017 May 31;6(2). pii: E22. doi: 10.3390/pathogens6020022.

9.

Phenotypic heterogeneity promotes adaptive evolution.

Bódi Z, Farkas Z, Nevozhay D, Kalapis D, Lázár V, Csörgő B, Nyerges Á, Szamecz B, Fekete G, Papp B, Araújo H, Oliveira JL, Moura G, Santos MAS, Székely T Jr, Balázsi G, Pál C.

PLoS Biol. 2017 May 9;15(5):e2000644. doi: 10.1371/journal.pbio.2000644. eCollection 2017 May. Erratum in: PLoS Biol. 2017 Jun 20;15(6):e1002607.

10.

Optimized silicon reinforcement of carbon coatings by pulsed laser technique for superior functional biomedical surfaces fabrication.

Mihailescu IN, Bociaga D, Popescu-Pelin G, Stan GE, Duta L, Socol G, Chifiriuc MC, Bleotu C, Lazar V, Husanu MA, Zgura I, Miculescu F, Negut I, Hapenciuc C.

Biofabrication. 2017 Jun 1;9(2):025029. doi: 10.1088/1758-5090/aa7076.

PMID:
28462910
11.

High-Throughput Genomics and Clinical Outcome in Hard-to-Treat Advanced Cancers: Results of the MOSCATO 01 Trial.

Massard C, Michiels S, Ferté C, Le Deley MC, Lacroix L, Hollebecque A, Verlingue L, Ileana E, Rosellini S, Ammari S, Ngo-Camus M, Bahleda R, Gazzah A, Varga A, Postel-Vinay S, Loriot Y, Even C, Breuskin I, Auger N, Job B, De Baere T, Deschamps F, Vielh P, Scoazec JY, Lazar V, Richon C, Ribrag V, Deutsch E, Angevin E, Vassal G, Eggermont A, André F, Soria JC.

Cancer Discov. 2017 Jun;7(6):586-595. doi: 10.1158/2159-8290.CD-16-1396. Epub 2017 Apr 1.

12.

Interaction of New-Developed TiO₂-Based Photocatalytic Nanoparticles with Pathogenic Microorganisms and Human Dermal and Pulmonary Fibroblasts.

Nica IC, Stan MS, Popa M, Chifiriuc MC, Lazar V, Pircalabioru GG, Dumitrescu I, Ignat M, Feder M, Tanase LC, Mercioniu I, Diamandescu L, Dinischiotu A.

Int J Mol Sci. 2017 Jan 25;18(2). pii: E249. doi: 10.3390/ijms18020249.

13.

Development and Sequential Analysis of a New Multi-Agent, Anti-Acne Formulation Based on Plant-Derived Antimicrobial and Anti-Inflammatory Compounds.

Saviuc C, Ciubucă B, Dincă G, Bleotu C, Drumea V, Chifiriuc MC, Popa M, Gradisteanu Pircalabioru G, Marutescu L, Lazăr V.

Int J Mol Sci. 2017 Jan 17;18(1). pii: E175. doi: 10.3390/ijms18010175.

14.

Shared and unique patterns of phenotypic diversification along a stream gradient in two congeneric species.

Jourdan J, Krause ST, Lazar VM, Zimmer C, Sommer-Trembo C, Arias-Rodriguez L, Klaus S, Riesch R, Plath M.

Sci Rep. 2016 Dec 16;6:38971. doi: 10.1038/srep38971.

15.

Microbial Biofilms in Urinary Tract Infections and Prostatitis: Etiology, Pathogenicity, and Combating strategies.

Delcaru C, Alexandru I, Podgoreanu P, Grosu M, Stavropoulos E, Chifiriuc MC, Lazar V.

Pathogens. 2016 Nov 30;5(4). pii: E65. Review.

16.

Novel insight into triple-negative breast cancers, the emerging role of angiogenesis, and antiangiogenic therapy.

Braicu C, Chiorean R, Irimie A, Chira S, Tomuleasa C, Neagoe E, Paradiso A, Achimas-Cadariu P, Lazar V, Berindan-Neagoe I.

Expert Rev Mol Med. 2016 Nov 7;18:e18. Review.

PMID:
27817751
17.

MMS19 as a potential predictive marker of adjuvant chemotherapy benefit in resected non-small cell lung cancer.

Adam J, Sourisseau T, Olaussen KA, Robin A, Zhu CQ, Templier A, Civet A, Girard P, Lazar V, Validire P, Tsao MS, Soria JC, Besse B.

Cancer Biomark. 2016 Sep 26;17(3):323-333.

PMID:
27802208
18.

DUX4-induced constitutive DNA damage and oxidative stress contribute to aberrant differentiation of myoblasts from FSHD patients.

Dmitriev P, Bou Saada Y, Dib C, Ansseau E, Barat A, Hamade A, Dessen P, Robert T, Lazar V, Louzada RAN, Dupuy C, Zakharova V, Carnac G, Lipinski M, Vassetzky YS.

Free Radic Biol Med. 2016 Oct;99:244-258. doi: 10.1016/j.freeradbiomed.2016.08.007. Epub 2016 Aug 9.

PMID:
27519269
19.

Antibiotics: New recipe for targeting resistance.

Papp B, Lázár V.

Nat Chem Biol. 2016 Oct 18;12(11):891-892. doi: 10.1038/nchembio.2215. No abstract available.

PMID:
27755526
20.

First report of OXA-72 producing Acinetobacter baumannii in Romania.

Georgescu M, Gheorghe I, Dudu A, Czobor I, Costache M, Cristea VC, Lazăr V, Chifiriuc MC.

New Microbes New Infect. 2016 Jul 21;13:87-8. doi: 10.1016/j.nmni.2016.07.004. eCollection 2016 Sep.

21.

Efficient transmission of IncFIIY and IncL plasmids and Klebsiella pneumoniae ST101 clone producing OXA-48, NDM-1 or OXA-181 in Bucharest hospitals.

Czobor I, Novais Â, Rodrigues C, Chifiriuc MC, Mihăescu G, Lazăr V, Peixe L.

Int J Antimicrob Agents. 2016 Aug;48(2):223-4. doi: 10.1016/j.ijantimicag.2016.05.004. Epub 2016 Jun 23. No abstract available.

PMID:
27378198
22.

Fabrication, Characterization, and Evaluation of Bionanocomposites Based on Natural Polymers and Antibiotics for Wound Healing Applications.

Rădulescu M, Holban AM, Mogoantă L, Bălşeanu TA, Mogoșanu GD, Savu D, Popescu RC, Fufă O, Grumezescu AM, Bezirtzoglou E, Lazar V, Chifiriuc MC.

Molecules. 2016 Jun 10;21(6). pii: E761. doi: 10.3390/molecules21060761.

23.

Association of Biomarker-Based Treatment Strategies With Response Rates and Progression-Free Survival in Refractory Malignant Neoplasms: A Meta-analysis.

Schwaederle M, Zhao M, Lee JJ, Lazar V, Leyland-Jones B, Schilsky RL, Mendelsohn J, Kurzrock R.

JAMA Oncol. 2016 Nov 1;2(11):1452-1459. doi: 10.1001/jamaoncol.2016.2129.

PMID:
27273579
24.

Adaptive evolution of complex innovations through stepwise metabolic niche expansion.

Szappanos B, Fritzemeier J, Csörgő B, Lázár V, Lu X, Fekete G, Bálint B, Herczeg R, Nagy I, Notebaart RA, Lercher MJ, Pál C, Papp B.

Nat Commun. 2016 May 20;7:11607. doi: 10.1038/ncomms11607.

25.

Virulence and resistance features of Pseudomonas aeruginosa strains isolated from chronic leg ulcers.

Georgescu M, Gheorghe I, Curutiu C, Lazar V, Bleotu C, Chifiriuc MC.

BMC Infect Dis. 2016 Mar 8;16 Suppl 1:92. doi: 10.1186/s12879-016-1396-3.

26.

Antimicrobial coatings based on zinc oxide and orange oil for improved bioactive wound dressings and other applications.

Rădulescu M, Andronescu E, Cirja A, Holban AM, Mogoantă L, Bălşeanu TA, Cătălin B, Neagu TP, Lascăr I, Florea DA, Grumezescu AM, Ciubuca B, Lazăr V, Chifiriuc MC, Bolocan A.

Rom J Morphol Embryol. 2016;57(1):107-14.

27.

Pregaming, Drinking Duration, and Movement as Unique Predictors of Alcohol Use and Cognitions Among Mandated College Students.

Yurasek A, Miller MB, Mastroleo N, Lazar V, Borsari B.

Subst Use Misuse. 2016 Jul 2;51(8):993-1001. doi: 10.3109/10826084.2016.1152491. Epub 2016 Apr 12.

28.

Antagonistic activities of some Bifidobacterium sp. strains isolated from resident infant gastrointestinal microbiota on Gram-negative enteric pathogens.

Delcaru C, Alexandru I, Podgoreanu P, Cristea VC, Bleotu C, Chifiriuc MC, Bezirtzoglou E, Lazar V.

Anaerobe. 2016 Jun;39:39-44. doi: 10.1016/j.anaerobe.2016.02.010. Epub 2016 Feb 26.

PMID:
26921694
29.

A highly precise and portable genome engineering method allows comparison of mutational effects across bacterial species.

Nyerges Á, Csörgő B, Nagy I, Bálint B, Bihari P, Lázár V, Apjok G, Umenhoffer K, Bogos B, Pósfai G, Pál C.

Proc Natl Acad Sci U S A. 2016 Mar 1;113(9):2502-7. doi: 10.1073/pnas.1520040113. Epub 2016 Feb 16.

30.

Efficiency of gentamicin loaded in bacterial polysaccharides microcapsules against intracellular Gram-positive and Gram-negative invasive pathogens.

Croitoru CD, Mihaiescu DE, Chifiriuc MC, Bolocan A, Bleotu C, Grumezescu AM, Saviuc CM, Lazăr V, Curuţiu C.

Rom J Morphol Embryol. 2015;56(4):1417-21.

31.

Effects of Pseudomonas aeruginosa infection on the expression profile of transient receptor potential-like (TRPL) gene from Drosophila melanogaster.

Mihalache (Radu) MR, Raþiu AC, Neagu A, Lazãr V, Chifiriuc MC, Ecovoiu AA.

Roum Arch Microbiol Immunol. 2016 Jan-Jun;75(1-2):32-6.

PMID:
29616531
32.

Expression signature of some immunity genes triggered in Apis mellifera carpatica model by Pseudomonas entomophila experimental infection.

Neagu A, Raþiu AC, Mihalache (Radu) MR, Lazãr V, Chifiriuc MC, Ecovoiu AA.

Roum Arch Microbiol Immunol. 2016 Jan-Jun;75(1-2):18-24.

PMID:
29616529
33.

Innovative Self-Cleaning and Biocompatible Polyester Textiles Nano-Decorated with Fe-N-Doped Titanium Dioxide.

Nica IC, Stan MS, Dinischiotu A, Popa M, Chifiriuc MC, Lazar V, Pircalabioru GG, Bezirtzoglou E, Iordache OG, Varzaru E, Dumitrescu I, Feder M, Vasiliu F, Mercioniu I, Diamandescu L.

Nanomaterials (Basel). 2016 Nov 15;6(11). pii: E214. doi: 10.3390/nano6110214.

34.
35.

Phenotypic and Genetic Evaluation of the Influence of Pseudomonas aeruginosa Culture Fractions on the Human Mesenchymal Stem Cells Viability, Apoptotic Pathways and Cytokine Profile.

Holban AM, Bleotu C, Chifiriuc MC, Lazar V.

Curr Stem Cell Res Ther. 2017;12(2):175-180. doi: 10.2174/1574888X10666151026114817.

PMID:
26496886
36.

Chemical Composition and Antipathogenic Activity of Artemisia annua Essential Oil from Romania.

Marinas IC, Oprea E, Chifiriuc MC, Badea IA, Buleandra M, Lazar V.

Chem Biodivers. 2015 Oct;12(10):1554-64. doi: 10.1002/cbdv.201400340.

PMID:
26460560
37.

Impact of a Biomarker-Based Strategy on Oncology Drug Development: A Meta-analysis of Clinical Trials Leading to FDA Approval.

Jardim DL, Schwaederle M, Wei C, Lee JJ, Hong DS, Eggermont AM, Schilsky RL, Mendelsohn J, Lazar V, Kurzrock R.

J Natl Cancer Inst. 2015 Sep 15;107(11). pii: djv253. doi: 10.1093/jnci/djv253. Print 2015 Nov. Erratum in: J Natl Cancer Inst. 2016 Feb;108(2). pii: djv423. doi: 10.1093/jnci/djv423.

38.

Identifying and Assessing Interesting Subgroups in a Heterogeneous Population.

Lee W, Alexeyenko A, Pernemalm M, Guegan J, Dessen P, Lazar V, Lehtiö J, Pawitan Y.

Biomed Res Int. 2015;2015:462549. doi: 10.1155/2015/462549. Epub 2015 Aug 3.

39.

Impact of Precision Medicine in Diverse Cancers: A Meta-Analysis of Phase II Clinical Trials.

Schwaederle M, Zhao M, Lee JJ, Eggermont AM, Schilsky RL, Mendelsohn J, Lazar V, Kurzrock R.

J Clin Oncol. 2015 Nov 10;33(32):3817-25. doi: 10.1200/JCO.2015.61.5997. Epub 2015 Aug 24. Review.

40.

Influence of Staphylococcus aureus attachment to the herpes simplex virus infected cells.

Bleotu C, Chifiriuc MC, Lazăr V, Drăguşel R, Matei L, Aldea IM, Dragu LD, Ionescu B, Diaconu CC, Cernescu C, Mogoantă CA, Popescu CR, Popescu B, Grigore R, Berteşteanu ŞV.

Rom J Morphol Embryol. 2015;56(2):433-7.

41.

A simplified interventional mapping system (SIMS) for the selection of combinations of targeted treatments in non-small cell lung cancer.

Lazar V, Rubin E, Depil S, Pawitan Y, Martini JF, Gomez-Navarro J, Yver A, Kan Z, Dry JR, Kehren J, Validire P, Rodon J, Vielh P, Ducreux M, Galbraith S, Lehnert M, Onn A, Berger R, Pierotti MA, Porgador A, Pramesh CS, Ye DW, Carvalho AL, Batist G, Le Chevalier T, Morice P, Besse B, Vassal G, Mortlock A, Hansson J, Berindan-Neagoe I, Dann R, Haspel J, Irimie A, Laderman S, Nechushtan H, Al Omari AS, Haywood T, Bresson C, Soo KC, Osman I, Mata H, Lee JJ, Jhaveri K, Meurice G, Palmer G, Lacroix L, Koscielny S, Eterovic KA, Blay JY, Buller R, Eggermont A, Schilsky RL, Mendelsohn J, Soria JC, Rothenberg M, Scoazec JY, Hong WK, Kurzrock R.

Oncotarget. 2015 Jun 10;6(16):14139-52.

42.

Challenges in initiating and conducting personalized cancer therapy trials: perspectives from WINTHER, a Worldwide Innovative Network (WIN) Consortium trial.

Rodon J, Soria JC, Berger R, Batist G, Tsimberidou A, Bresson C, Lee JJ, Rubin E, Onn A, Schilsky RL, Miller WH, Eggermont AM, Mendelsohn J, Lazar V, Kurzrock R.

Ann Oncol. 2015 Aug;26(8):1791-8. doi: 10.1093/annonc/mdv191. Epub 2015 Apr 23.

43.

Microbial biofilms: impact on the pathogenesis of periodontitis, cystic fibrosis, chronic wounds and medical device-related infections.

Mihai MM, Holban AM, Giurcaneanu C, Popa LG, Oanea RM, Lazar V, Chifiriuc MC, Popa M, Popa MI.

Curr Top Med Chem. 2015;15(16):1552-76. Review.

PMID:
25877092
44.

Metallic-based micro and nanostructures with antimicrobial activity.

Pop CS, Hussien MD, Popa M, Mares A, Grumezescu AM, Grigore R, Lazar V, Chifiriuc MC, Sakizlian M, Bezirtzoglou E, Bertesteanu S.

Curr Top Med Chem. 2015;15(16):1577-82. Review.

PMID:
25877091
45.

Insights on Metal Based Dental Implants and their Interaction with the Surrounding Tissues.

Popa M, Hussien MD, Cirstea A, Grigore R, Lazar V, Bezirtzoglou E, Chifiriuc MC, Sakizlian M, Stavropoulou E, Bertesteanu S.

Curr Top Med Chem. 2015;15(16):1614-21. Review.

PMID:
25877088
46.

Collateral sensitivity of antibiotic-resistant microbes.

Pál C, Papp B, Lázár V.

Trends Microbiol. 2015 Jul;23(7):401-7. doi: 10.1016/j.tim.2015.02.009. Epub 2015 Mar 25. Review.

47.

Comparative analysis of primary tumour and matched metastases in colorectal cancer patients: evaluation of concordance between genomic and transcriptional profiles.

Vignot S, Lefebvre C, Frampton GM, Meurice G, Yelensky R, Palmer G, Capron F, Lazar V, Hannoun L, Miller VA, André F, Stephens PJ, Soria JC, Spano JP.

Eur J Cancer. 2015 May;51(7):791-9. doi: 10.1016/j.ejca.2015.02.012. Epub 2015 Mar 18.

PMID:
25797355
48.

Recognition and Impact of Host-derived Molecules on Bacterial Cell-to-cell Signalling Pathways.

Holban AM, Chifiriuc MC, Lazar V.

Med Chem. 2015;11(7):610-7. Review.

PMID:
25741882
49.

VEGF-A Expression Correlates with TP53 Mutations in Non-Small Cell Lung Cancer: Implications for Antiangiogenesis Therapy.

Schwaederlé M, Lazar V, Validire P, Hansson J, Lacroix L, Soria JC, Pawitan Y, Kurzrock R.

Cancer Res. 2015 Apr 1;75(7):1187-90. doi: 10.1158/0008-5472.CAN-14-2305. Epub 2015 Feb 11.

50.

Snapshot on carbapenemase-producing Pseudomonas aeruginosa and Acinetobacter baumannii in Bucharest hospitals reveals unusual clones and novel genetic surroundings for blaOXA-23.

Gheorghe I, Novais Â, Grosso F, Rodrigues C, Chifiriuc MC, Lazar V, Peixe L.

J Antimicrob Chemother. 2015 Apr;70(4):1016-20. doi: 10.1093/jac/dku527. Epub 2015 Jan 27.

PMID:
25630639

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