Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 312

1.

Identification of C2CD4A as a human diabetes susceptibility gene with a role in β cell insulin secretion.

Kuo T, Kraakman MJ, Damle M, Gill R, Lazar MA, Accili D.

Proc Natl Acad Sci U S A. 2019 Sep 16. pii: 201904311. doi: 10.1073/pnas.1904311116. [Epub ahead of print]

PMID:
31527256
2.

Circadian lipid synthesis in brown fat maintains murine body temperature during chronic cold.

Adlanmerini M, Carpenter BJ, Remsberg JR, Aubert Y, Peed LC, Richter HJ, Lazar MA.

Proc Natl Acad Sci U S A. 2019 Sep 10;116(37):18691-18699. doi: 10.1073/pnas.1909883116. Epub 2019 Aug 26.

PMID:
31451658
3.

Lipid-Associated Macrophages Control Metabolic Homeostasis in a Trem2-Dependent Manner.

Jaitin DA, Adlung L, Thaiss CA, Weiner A, Li B, Descamps H, Lundgren P, Bleriot C, Liu Z, Deczkowska A, Keren-Shaul H, David E, Zmora N, Eldar SM, Lubezky N, Shibolet O, Hill DA, Lazar MA, Colonna M, Ginhoux F, Shapiro H, Elinav E, Amit I.

Cell. 2019 Jul 25;178(3):686-698.e14. doi: 10.1016/j.cell.2019.05.054. Epub 2019 Jun 27.

PMID:
31257031
4.

Exercise test is essential in LV-only fusion CRT pacing without right ventricle lead.

Vacarescu C, Cozma D, Petrescu L, Dragan S, Mornos C, Crisan S, Feier H, Lazar MA, Cozlac RA, Luca CT.

Clin Interv Aging. 2019 Jun 4;14:969-975. doi: 10.2147/CIA.S206251. eCollection 2019.

5.

SR9009 has REV-ERB-independent effects on cell proliferation and metabolism.

Dierickx P, Emmett MJ, Jiang C, Uehara K, Liu M, Adlanmerini M, Lazar MA.

Proc Natl Acad Sci U S A. 2019 Jun 18;116(25):12147-12152. doi: 10.1073/pnas.1904226116. Epub 2019 May 24.

PMID:
31127047
6.

Induction of α cell-restricted Gc in dedifferentiating β cells contributes to stress-induced β-cell dysfunction.

Kuo T, Damle M, González BJ, Egli D, Lazar MA, Accili D.

JCI Insight. 2019 May 23;5. pii: 128351. doi: 10.1172/jci.insight.128351.

7.

Dysregulation of a long noncoding RNA reduces leptin leading to a leptin-responsive form of obesity.

Dallner OS, Marinis JM, Lu YH, Birsoy K, Werner E, Fayzikhodjaeva G, Dill BD, Molina H, Moscati A, Kutalik Z, Marques-Vidal P, Kilpeläinen TO, Grarup N, Linneberg A, Zhang Y, Vaughan R, Loos RJF, Lazar MA, Friedman JM.

Nat Med. 2019 Mar;25(3):507-516. doi: 10.1038/s41591-019-0370-1. Epub 2019 Mar 6.

PMID:
30842678
8.

Patient Adipose Stem Cell-Derived Adipocytes Reveal Genetic Variation that Predicts Antidiabetic Drug Response.

Hu W, Jiang C, Guan D, Dierickx P, Zhang R, Moscati A, Nadkarni GN, Steger DJ, Loos RJF, Hu C, Jia W, Soccio RE, Lazar MA.

Cell Stem Cell. 2019 Feb 7;24(2):299-308.e6. doi: 10.1016/j.stem.2018.11.018. Epub 2019 Jan 10.

PMID:
30639037
9.

Oral surgery for combined haemophilia A and B. The dos and don'ts presented in a clinical scenario.

Lazar MA, Muresan O, Roman CR, Dima D, Muresan MS, Armencea G, Tomuleasa C, Rotaru H.

Ann Ital Chir. 2018;89:374-378.

PMID:
30569902
10.

Toxicity of overexpressed MeCP2 is independent of HDAC3 activity.

Koerner MV, FitzPatrick L, Selfridge J, Guy J, De Sousa D, Tillotson R, Kerr A, Sun Z, Lazar MA, Lyst MJ, Bird A.

Genes Dev. 2018 Dec 1;32(23-24):1514-1524. doi: 10.1101/gad.320325.118. Epub 2018 Nov 21.

11.

Integrative regulation of physiology by histone deacetylase 3.

Emmett MJ, Lazar MA.

Nat Rev Mol Cell Biol. 2019 Feb;20(2):102-115. doi: 10.1038/s41580-018-0076-0. Review.

12.

Diet-Induced Circadian Enhancer Remodeling Synchronizes Opposing Hepatic Lipid Metabolic Processes.

Guan D, Xiong Y, Borck PC, Jang C, Doulias PT, Papazyan R, Fang B, Jiang C, Zhang Y, Briggs ER, Hu W, Steger D, Ischiropoulos H, Rabinowitz JD, Lazar MA.

Cell. 2018 Aug 9;174(4):831-842.e12. doi: 10.1016/j.cell.2018.06.031. Epub 2018 Jul 26.

13.

PPARγ is a nexus controlling alternative activation of macrophages via glutamine metabolism.

Nelson VL, Nguyen HCB, Garcìa-Cañaveras JC, Briggs ER, Ho WY, DiSpirito JR, Marinis JM, Hill DA, Lazar MA.

Genes Dev. 2018 Aug 1;32(15-16):1035-1044. doi: 10.1101/gad.312355.118. Epub 2018 Jul 13.

14.

A noncanonical PPARγ/RXRα-binding sequence regulates leptin expression in response to changes in adipose tissue mass.

Zhang Y, Dallner OS, Nakadai T, Fayzikhodjaeva G, Lu YH, Lazar MA, Roeder RG, Friedman JM.

Proc Natl Acad Sci U S A. 2018 Jun 26;115(26):E6039-E6047. doi: 10.1073/pnas.1806366115. Epub 2018 Jun 11.

15.

Observational study of the bisphosphonate-related osteonecrosis of jaws.

Lungu AE, Lazar MA, Tonea A, Rotaru H, Roman RC, Badea ME.

Clujul Med. 2018;91(2):209-215. doi: 10.15386/cjmed-838. Epub 2018 Apr 25.

16.

Distinct macrophage populations direct inflammatory versus physiological changes in adipose tissue.

Hill DA, Lim HW, Kim YH, Ho WY, Foong YH, Nelson VL, Nguyen HCB, Chegireddy K, Kim J, Habertheuer A, Vallabhajosyula P, Kambayashi T, Won KJ, Lazar MA.

Proc Natl Acad Sci U S A. 2018 May 29;115(22):E5096-E5105. doi: 10.1073/pnas.1802611115. Epub 2018 May 14.

17.

Reversing the curse on PPARγ.

Lazar MA.

J Clin Invest. 2018 Jun 1;128(6):2202-2204. doi: 10.1172/JCI121392. Epub 2018 May 14.

18.

Nighttime light exposure enhances Rev-erbα-targeting microRNAs and contributes to hepatic steatosis.

Borck PC, Batista TM, Vettorazzi JF, Soares GM, Lubaczeuski C, Guan D, Boschero AC, Vieira E, Lazar MA, Carneiro EM.

Metabolism. 2018 Aug;85:250-258. doi: 10.1016/j.metabol.2018.05.002. Epub 2018 May 8.

19.

β-Adrenergic receptors control brown adipose UCP-1 tone and cold response without affecting its circadian rhythmicity.

Razzoli M, Emmett MJ, Lazar MA, Bartolomucci A.

FASEB J. 2018 Oct;32(10):5640-5646. doi: 10.1096/fj.201800452R. Epub 2018 May 1.

PMID:
29715048
20.

Reduced ejection fraction heart failure - new data from multicenter studies and national registries regarding general and elderly populations: hopes and disappointments.

Crişan S, Petrescu L, Lazăr MA, Văcărescu C, Nicola AR, Cozma D, Mornoş C, Luca CT.

Clin Interv Aging. 2018 Apr 18;13:651-656. doi: 10.2147/CIA.S161385. eCollection 2018.

21.

Rev-erbα dynamically modulates chromatin looping to control circadian gene transcription.

Kim YH, Marhon SA, Zhang Y, Steger DJ, Won KJ, Lazar MA.

Science. 2018 Mar 16;359(6381):1274-1277. doi: 10.1126/science.aao6891. Epub 2018 Feb 8.

22.

Human resistin protects against endotoxic shock by blocking LPS-TLR4 interaction.

Jang JC, Li J, Gambini L, Batugedara HM, Sati S, Lazar MA, Fan L, Pellecchia M, Nair MG.

Proc Natl Acad Sci U S A. 2017 Nov 28;114(48):E10399-E10408. doi: 10.1073/pnas.1716015114. Epub 2017 Nov 13.

23.

Genome-Nuclear Lamina Interactions Regulate Cardiac Stem Cell Lineage Restriction.

Poleshko A, Shah PP, Gupta M, Babu A, Morley MP, Manderfield LJ, Ifkovits JL, Calderon D, Aghajanian H, Sierra-Pagán JE, Sun Z, Wang Q, Li L, Dubois NC, Morrisey EE, Lazar MA, Smith CL, Epstein JA, Jain R.

Cell. 2017 Oct 19;171(3):573-587.e14. doi: 10.1016/j.cell.2017.09.018. Epub 2017 Oct 12.

24.

An HDAC3-PROX1 corepressor module acts on HNF4α to control hepatic triglycerides.

Armour SM, Remsberg JR, Damle M, Sidoli S, Ho WY, Li Z, Garcia BA, Lazar MA.

Nat Commun. 2017 Sep 15;8(1):549. doi: 10.1038/s41467-017-00772-5.

25.

Rev-erbs: Integrating Metabolism Around the Clock.

Lazar MA.

In: Sassone-Corsi P, Christen Y, editors. A Time for Metabolism and Hormones [Internet]. Cham (CH): Springer; 2016.
2016 Apr 5.

26.

The hepatic circadian clock fine-tunes the lipogenic response to feeding through RORα/γ.

Zhang Y, Papazyan R, Damle M, Fang B, Jager J, Feng D, Peed LC, Guan D, Sun Z, Lazar MA.

Genes Dev. 2017 Jun 15;31(12):1202-1211. doi: 10.1101/gad.302323.117. Epub 2017 Jul 26.

27.

Histone deacetylase 3 prepares brown adipose tissue for acute thermogenic challenge.

Emmett MJ, Lim HW, Jager J, Richter HJ, Adlanmerini M, Peed LC, Briggs ER, Steger DJ, Ma T, Sims CA, Baur JA, Pei L, Won KJ, Seale P, Gerhart-Hines Z, Lazar MA.

Nature. 2017 Jun 22;546(7659):544-548. doi: 10.1038/nature22819. Epub 2017 Jun 14.

28.

Unraveling the Regulation of Hepatic Metabolism by Insulin.

Titchenell PM, Lazar MA, Birnbaum MJ.

Trends Endocrinol Metab. 2017 Jul;28(7):497-505. doi: 10.1016/j.tem.2017.03.003. Epub 2017 Apr 14. Review.

29.

Maturing of the nuclear receptor family.

Lazar MA.

J Clin Invest. 2017 Apr 3;127(4):1123-1125. doi: 10.1172/JCI92949. Epub 2017 Apr 3. Review.

30.

Targeting PPARγ in the epigenome rescues genetic metabolic defects in mice.

Soccio RE, Li Z, Chen ER, Foong YH, Benson KK, Dispirito JR, Mullican SE, Emmett MJ, Briggs ER, Peed LC, Dzeng RK, Medina CJ, Jolivert JF, Kissig M, Rajapurkar SR, Damle M, Lim HW, Won KJ, Seale P, Steger DJ, Lazar MA.

J Clin Invest. 2017 Apr 3;127(4):1451-1462. doi: 10.1172/JCI91211. Epub 2017 Feb 27.

31.

Deletion of histone deacetylase 3 in adult beta cells improves glucose tolerance via increased insulin secretion.

Remsberg JR, Ediger BN, Ho WY, Damle M, Li Z, Teng C, Lanzillotta C, Stoffers DA, Lazar MA.

Mol Metab. 2016 Nov 22;6(1):30-37. doi: 10.1016/j.molmet.2016.11.007. eCollection 2017 Jan.

32.

Regeneration of fat cells from myofibroblasts during wound healing.

Plikus MV, Guerrero-Juarez CF, Ito M, Li YR, Dedhia PH, Zheng Y, Shao M, Gay DL, Ramos R, Hsi TC, Oh JW, Wang X, Ramirez A, Konopelski SE, Elzein A, Wang A, Supapannachart RJ, Lee HL, Lim CH, Nace A, Guo A, Treffeisen E, Andl T, Ramirez RN, Murad R, Offermanns S, Metzger D, Chambon P, Widgerow AD, Tuan TL, Mortazavi A, Gupta RK, Hamilton BA, Millar SE, Seale P, Pear WS, Lazar MA, Cotsarelis G.

Science. 2017 Feb 17;355(6326):748-752. doi: 10.1126/science.aai8792. Epub 2017 Jan 5.

33.

Dissociation of muscle insulin sensitivity from exercise endurance in mice by HDAC3 depletion.

Hong S, Zhou W, Fang B, Lu W, Loro E, Damle M, Ding G, Jager J, Zhang S, Zhang Y, Feng D, Chu Q, Dill BD, Molina H, Khurana TS, Rabinowitz JD, Lazar MA, Sun Z.

Nat Med. 2017 Feb;23(2):223-234. doi: 10.1038/nm.4245. Epub 2016 Dec 19.

34.

Genetic and epigenomic mechanisms of mammalian circadian transcription.

Papazyan R, Zhang Y, Lazar MA.

Nat Struct Mol Biol. 2016 Dec 6;23(12):1045-1052. doi: 10.1038/nsmb.3324. Review.

35.

Circadian time signatures of fitness and disease.

Bass J, Lazar MA.

Science. 2016 Nov 25;354(6315):994-999. Review.

PMID:
27885004
36.

Physiological Suppression of Lipotoxic Liver Damage by Complementary Actions of HDAC3 and SCAP/SREBP.

Papazyan R, Sun Z, Kim YH, Titchenell PM, Hill DA, Lu W, Damle M, Wan M, Zhang Y, Briggs ER, Rabinowitz JD, Lazar MA.

Cell Metab. 2016 Dec 13;24(6):863-874. doi: 10.1016/j.cmet.2016.10.012. Epub 2016 Nov 17.

37.

Evaluation of the Biocompatibility of New Fiber-Reinforced Composite Materials for Craniofacial Bone Reconstruction.

Lazar MA, Rotaru H, Bâldea I, Boşca AB, Berce CP, Prejmerean C, Prodan D, Câmpian RS.

J Craniofac Surg. 2016 Oct;27(7):1694-1699.

PMID:
27763970
38.

Genetic backgrounds determine brown remodeling of white fat in rodents.

Ferrannini G, Namwanje M, Fang B, Damle M, Li D, Liu Q, Lazar MA, Qiang L.

Mol Metab. 2016 Aug 26;5(10):948-958. doi: 10.1016/j.molmet.2016.08.013. eCollection 2016 Oct.

39.

Antibacterial coating on biocomposites for cranio-facial reconstruction.

Lazar MA, Vodnar D, Prodan D, Rotaru H, Roman CR, Sorcoi LA, Baciut G, Campian RS.

Clujul Med. 2016;89(3):430-4. doi: 10.15386/cjmed-599. Epub 2016 Jul 28.

40.

HNF6 and Rev-erbα integrate hepatic lipid metabolism by overlapping and distinct transcriptional mechanisms.

Zhang Y, Fang B, Damle M, Guan D, Li Z, Kim YH, Gannon M, Lazar MA.

Genes Dev. 2016 Jul 15;30(14):1636-44. doi: 10.1101/gad.281972.116. Epub 2016 Jul 21.

41.

Lactate Dehydrogenase C Produces S-2-Hydroxyglutarate in Mouse Testis.

Teng X, Emmett MJ, Lazar MA, Goldberg E, Rabinowitz JD.

ACS Chem Biol. 2016 Sep 16;11(9):2420-7. doi: 10.1021/acschembio.6b00290. Epub 2016 Jul 7.

42.

Hdac3 Interaction with p300 Histone Acetyltransferase Regulates the Oligodendrocyte and Astrocyte Lineage Fate Switch.

Zhang L, He X, Liu L, Jiang M, Zhao C, Wang H, He D, Zheng T, Zhou X, Hassan A, Ma Z, Xin M, Sun Z, Lazar MA, Goldman SA, Olson EN, Richard Lu Q.

Dev Cell. 2016 Jun 20;37(6):582. doi: 10.1016/j.devcel.2016.06.004. No abstract available.

43.

The Nuclear Receptor Rev-erbα Regulates Adipose Tissue-specific FGF21 Signaling.

Jager J, Wang F, Fang B, Lim HW, Peed LC, Steger DJ, Won KJ, Kharitonenkov A, Adams AC, Lazar MA.

J Biol Chem. 2016 May 13;291(20):10867-75. doi: 10.1074/jbc.M116.719120. Epub 2016 Mar 21.

44.

Hdac3 Interaction with p300 Histone Acetyltransferase Regulates the Oligodendrocyte and Astrocyte Lineage Fate Switch.

Zhang L, He X, Liu L, Jiang M, Zhao C, Wang H, He D, Zheng T, Zhou X, Hassan A, Ma Z, Xin M, Sun Z, Lazar MA, Goldman SA, Olson EN, Lu QR.

Dev Cell. 2016 Feb 8;36(3):316-30. doi: 10.1016/j.devcel.2016.01.002.

45.

HDAC3-Dependent Epigenetic Pathway Controls Lung Alveolar Epithelial Cell Remodeling and Spreading via miR-17-92 and TGF-β Signaling Regulation.

Wang Y, Frank DB, Morley MP, Zhou S, Wang X, Lu MM, Lazar MA, Morrisey EE.

Dev Cell. 2016 Feb 8;36(3):303-15. doi: 10.1016/j.devcel.2015.12.031. Epub 2016 Jan 28.

46.

MYC Disrupts the Circadian Clock and Metabolism in Cancer Cells.

Altman BJ, Hsieh AL, Sengupta A, Krishnanaiah SY, Stine ZE, Walton ZE, Gouw AM, Venkataraman A, Li B, Goraksha-Hicks P, Diskin SJ, Bellovin DI, Simon MC, Rathmell JC, Lazar MA, Maris JM, Felsher DW, Hogenesch JB, Weljie AM, Dang CV.

Cell Metab. 2015 Dec 1;22(6):1009-19. doi: 10.1016/j.cmet.2015.09.003. Epub 2015 Sep 17.

47.

Dissecting the Rev-erbα Cistrome and the Mechanisms Controlling Circadian Transcription in Liver.

Fang B, Lazar MA.

Cold Spring Harb Symp Quant Biol. 2015;80:233-8. doi: 10.1101/sqb.2015.80.027508. Epub 2015 Sep 14. Review.

PMID:
26370410
48.

Enhanced thermal energy harvesting performance of a cobalt redox couple in ionic liquid-solvent mixtures.

Lazar MA, Al-Masri D, MacFarlane DR, Pringle JM.

Phys Chem Chem Phys. 2016 Jan 21;18(3):1404-10. doi: 10.1039/c5cp04305k. Epub 2015 Sep 8.

PMID:
26348719
49.

Rev-erbα and the circadian transcriptional regulation of metabolism.

Gerhart-Hines Z, Lazar MA.

Diabetes Obes Metab. 2015 Sep;17 Suppl 1:12-6. doi: 10.1111/dom.12510. Review.

50.

Genetic Variation Determines PPARγ Function and Anti-diabetic Drug Response In Vivo.

Soccio RE, Chen ER, Rajapurkar SR, Safabakhsh P, Marinis JM, Dispirito JR, Emmett MJ, Briggs ER, Fang B, Everett LJ, Lim HW, Won KJ, Steger DJ, Wu Y, Civelek M, Voight BF, Lazar MA.

Cell. 2015 Jul 2;162(1):33-44. doi: 10.1016/j.cell.2015.06.025.

Supplemental Content

Loading ...
Support Center