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Items: 1 to 50 of 111

1.

Transferrin Cycle and Clinical Roles of Citrate and Ascorbate in Improved Iron Metabolism.

Levina A, Lay PA.

ACS Chem Biol. 2019 May 17;14(5):893-900. doi: 10.1021/acschembio.8b01100. Epub 2019 Apr 24.

PMID:
30973710
2.

Hydrophobicity may enhance membrane affinity and anti-cancer effects of Schiff base vanadium(v) catecholate complexes.

Crans DC, Koehn JT, Petry SM, Glover CM, Wijetunga A, Kaur R, Levina A, Lay PA.

Dalton Trans. 2019 May 15;48(19):6383-6395. doi: 10.1039/c9dt00601j.

PMID:
30941380
3.

Reactivity and Transformation of Antimetastatic and Cytotoxic Rhodium(III)-Dimethyl Sulfoxide Complexes in Biological Fluids: An XAS Speciation Study.

Liang J, Levina A, Jia J, Kappen P, Glover C, Johannessen B, Lay PA.

Inorg Chem. 2019 Apr 15;58(8):4880-4893. doi: 10.1021/acs.inorgchem.8b03477. Epub 2019 Apr 1.

PMID:
30932487
4.

Lipid profiles of prostate cancer cells.

Sorvina A, Bader CA, Caporale C, Carter EA, Johnson IRD, Parkinson-Lawrence EJ, Simpson PV, Wright PJ, Stagni S, Lay PA, Massi M, Brooks DA, Plush SE.

Oncotarget. 2018 Oct 30;9(85):35541-35552. doi: 10.18632/oncotarget.26222. eCollection 2018 Oct 30.

5.

Assessment tools for microplastics and natural fibres ingested by fish in an urbanised estuary.

Halstead JE, Smith JA, Carter EA, Lay PA, Johnston EL.

Environ Pollut. 2018 Mar;234:552-561. doi: 10.1016/j.envpol.2017.11.085. Epub 2017 Dec 21.

PMID:
29220787
6.

Imaging of Vanadium in Microfossils: A New Potential Biosignature.

Marshall CP, Olcott Marshall A, Aitken JB, Lai B, Vogt S, Breuer P, Steemans P, Lay PA.

Astrobiology. 2017 Nov;17(11):1069-1076. doi: 10.1089/ast.2017.1709. Epub 2017 Sep 14.

PMID:
28910135
7.

Stabilities and Biological Activities of Vanadium Drugs: What is the Nature of the Active Species?

Levina A, Lay PA.

Chem Asian J. 2017 Jul 18;12(14):1692-1699. doi: 10.1002/asia.201700463. Epub 2017 Jun 13. Review.

PMID:
28401668
8.

High cytotoxicity of vanadium(IV) complexes with 1,10-phenanthroline and related ligands is due to decomposition in cell culture medium.

Le M, Rathje O, Levina A, Lay PA.

J Biol Inorg Chem. 2017 Jul;22(5):663-672. doi: 10.1007/s00775-017-1453-4. Epub 2017 Apr 3.

PMID:
28374136
9.

Infrared spectroscopic characterization of monocytic microvesicles (microparticles) released upon lipopolysaccharide stimulation.

Lee J, Wen B, Carter EA, Combes V, Grau GER, Lay PA.

FASEB J. 2017 Jul;31(7):2817-2827. doi: 10.1096/fj.201601272R. Epub 2017 Mar 17.

PMID:
28314769
10.

A Molecular Probe for the Detection of Polar Lipids in Live Cells.

Bader CA, Shandala T, Carter EA, Ivask A, Guinan T, Hickey SM, Werrett MV, Wright PJ, Simpson PV, Stagni S, Voelcker NH, Lay PA, Massi M, Plush SE, Brooks DA.

PLoS One. 2016 Aug 23;11(8):e0161557. doi: 10.1371/journal.pone.0161557. eCollection 2016.

11.

Comparison of KP1019 and NAMI-A in tumour-mimetic environments.

Gransbury GK, Kappen P, Glover CJ, Hughes JN, Levina A, Lay PA, Musgrave IF, Harris HH.

Metallomics. 2016 Aug 1;8(8):762-73. doi: 10.1039/c6mt00145a.

PMID:
27460862
12.

Spectroscopic characterization of genotoxic chromium(V) peptide complexes: Oxidation of Chromium(III) triglycine, tetraglycine and pentaglycine complexes.

Headlam HA, Lay PA.

J Inorg Biochem. 2016 Sep;162:227-237. doi: 10.1016/j.jinorgbio.2016.06.015. Epub 2016 Jun 16.

PMID:
27365280
13.

Binding of Chromium(III) to Transferrin Could Be Involved in Detoxification of Dietary Chromium(III) Rather than Transport of an Essential Trace Element.

Levina A, Pham TH, Lay PA.

Angew Chem Int Ed Engl. 2016 Jul 4;55(28):8104-7. doi: 10.1002/anie.201602996. Epub 2016 May 20.

PMID:
27197571
14.

Unprecedented staining of polar lipids by a luminescent rhenium complex revealed by FTIR microspectroscopy in adipocytes.

Bader CA, Carter EA, Safitri A, Simpson PV, Wright P, Stagni S, Massi M, Lay PA, Brooks DA, Plush SE.

Mol Biosyst. 2016 Jun 21;12(7):2064-8. doi: 10.1039/c6mb00242k.

PMID:
27170554
15.

XAS spectroelectrochemistry: reliable measurement of X-ray absorption spectra from redox manipulated solutions at room temperature.

Best SP, Levina A, Glover C, Johannessen B, Kappen P, Lay PA.

J Synchrotron Radiat. 2016 May;23(Pt 3):743-50. doi: 10.1107/S1600577516005464. Epub 2016 Apr 14.

PMID:
27140154
16.

A novel class of copper(II)- and zinc(II)-bound non-steroidal anti-inflammatory drugs that inhibits acute inflammation in vivo.

Puranik R, Bao S, Bonin AM, Kaur R, Weder JE, Casbolt L, Hambley TW, Lay PA, Barter PJ, Rye KA.

Cell Biosci. 2016 Feb 6;6:9. doi: 10.1186/s13578-016-0076-8. eCollection 2016.

17.

Mechanisms of murine cerebral malaria: Multimodal imaging of altered cerebral metabolism and protein oxidation at hemorrhage sites.

Hackett MJ, Aitken JB, El-Assaad F, McQuillan JA, Carter EA, Ball HJ, Tobin MJ, Paterson D, de Jonge MD, Siegele R, Cohen DD, Vogt S, Grau GE, Hunt NH, Lay PA.

Sci Adv. 2015 Dec 18;1(11):e1500911. doi: 10.1126/sciadv.1500911. eCollection 2015 Dec.

18.

Uncovering system-specific stress signatures in primate teeth with multimodal imaging.

Austin C, Smith TM, Farahani RM, Hinde K, Carter EA, Lee J, Lay PA, Kennedy BJ, Sarrafpour B, Wright RJ, Wright RO, Arora M.

Sci Rep. 2016 Jan 4;6:18802. doi: 10.1038/srep18802.

19.

Simultaneous biosynthesis of putrebactin, avaroferrin and bisucaberin by Shewanella putrefaciens and characterisation of complexes with iron(III), molybdenum(VI) or chromium(V).

Soe CZ, Telfer TJ, Levina A, Lay PA, Codd R.

J Inorg Biochem. 2016 Sep;162:207-215. doi: 10.1016/j.jinorgbio.2015.12.008. Epub 2015 Dec 17.

PMID:
26723537
20.

Carcinogenic Chromium(VI) Compounds Formed by Intracellular Oxidation of Chromium(III) Dietary Supplements by Adipocytes.

Wu LE, Levina A, Harris HH, Cai Z, Lai B, Vogt S, James DE, Lay PA.

Angew Chem Int Ed Engl. 2016 Jan 26;55(5):1742-5. doi: 10.1002/anie.201509065. Epub 2015 Dec 22.

PMID:
26696553
21.

Reactivity and Speciation of Anti-Diabetic Vanadium Complexes in Whole Blood and Its Components: The Important Role of Red Blood Cells.

Levina A, McLeod AI, Gasparini SJ, Nguyen A, De Silva WG, Aitken JB, Harris HH, Glover C, Johannessen B, Lay PA.

Inorg Chem. 2015 Aug 17;54(16):7753-66. doi: 10.1021/acs.inorgchem.5b00665. Epub 2015 Jul 31.

PMID:
26230577
22.

Vanadium(V) and -(IV) complexes of anionic polysaccharides: Controlled release pharmaceutical formulations and models of vanadium biotransformation products.

Kremer LE, McLeod AI, Aitken JB, Levina A, Lay PA.

J Inorg Biochem. 2015 Jun;147:227-34. doi: 10.1016/j.jinorgbio.2015.03.016. Epub 2015 Apr 7.

PMID:
25958254
23.

Biotransformations of Antidiabetic Vanadium Prodrugs in Mammalian Cells and Cell Culture Media: A XANES Spectroscopic Study.

Levina A, McLeod AI, Pulte A, Aitken JB, Lay PA.

Inorg Chem. 2015 Jul 20;54(14):6707-18. doi: 10.1021/ic5028948. Epub 2015 Apr 23.

24.

Solid-state structural studies of chromium(III) nicotinato nutritional supplements.

Pham TH, Aitken JB, Levina A, Lay PA.

Inorg Chem. 2014 Oct 6;53(19):10685-94. doi: 10.1021/ic501818w. Epub 2014 Sep 15.

PMID:
25222599
25.

Reactivity-activity relationships of oral anti-diabetic vanadium complexes in gastrointestinal media: an X-ray absorption spectroscopic study.

Levina A, McLeod AI, Kremer LE, Aitken JB, Glover CJ, Johannessen B, Lay PA.

Metallomics. 2014 Oct;6(10):1880-8. doi: 10.1039/c4mt00146j. Epub 2014 Aug 6.

PMID:
25100248
26.

Vanadium speciation by XANES spectroscopy: a three-dimensional approach.

Levina A, McLeod AI, Lay PA.

Chemistry. 2014 Sep 15;20(38):12056-60. doi: 10.1002/chem.201403993. Epub 2014 Aug 1.

PMID:
25088743
27.

The Fe-heme structure of met-indoleamine 2,3-dioxygenase-2 determined by X-ray absorption fine structure.

Aitken JB, Austin CJ, Hunt NH, Ball HJ, Lay PA.

Biochem Biophys Res Commun. 2014 Jul 18;450(1):25-9. doi: 10.1016/j.bbrc.2014.05.054. Epub 2014 May 22.

PMID:
24858687
28.

Parkinson's disease-linked human PARK9/ATP13A2 maintains zinc homeostasis and promotes α-Synuclein externalization via exosomes.

Kong SM, Chan BK, Park JS, Hill KJ, Aitken JB, Cottle L, Farghaian H, Cole AR, Lay PA, Sue CM, Cooper AA.

Hum Mol Genet. 2014 Jun 1;23(11):2816-33. doi: 10.1093/hmg/ddu099. Epub 2014 Mar 6.

PMID:
24603074
29.

α-Hemoglobin-stabilizing protein (AHSP) perturbs the proximal heme pocket of oxy-α-hemoglobin and weakens the iron-oxygen bond.

Dickson CF, Rich AM, D'Avigdor WM, Collins DA, Lowry JA, Mollan TL, Khandros E, Olson JS, Weiss MJ, Mackay JP, Lay PA, Gell DA.

J Biol Chem. 2013 Jul 5;288(27):19986-20001. doi: 10.1074/jbc.M112.437509. Epub 2013 May 21.

30.

Intracellular targeting and pharmacological activity of the superoxide dismutase mimics MnTE-2-PyP5+ and MnTnHex-2-PyP5+ regulated by their porphyrin ring substituents.

Aitken JB, Shearer EL, Giles NM, Lai B, Vogt S, Reboucas JS, Batinic-Haberle I, Lay PA, Giles GI.

Inorg Chem. 2013 Apr 15;52(8):4121-3. doi: 10.1021/ic300700g. Epub 2013 Apr 3.

PMID:
23551184
31.

Isolation, characterization, and nuclease activity of biologically relevant chromium(V) complexes with monosaccharides and model diols. Likely intermediates in chromium-induced cancers.

Bartholomäus R, Irwin JA, Shi L, Smith SM, Levina A, Lay PA.

Inorg Chem. 2013 Apr 15;52(8):4282-92. doi: 10.1021/ic3022408. Epub 2013 Mar 26.

PMID:
23531300
32.

Biotransformations of anticancer ruthenium(III) complexes: an X-ray absorption spectroscopic study.

Levina A, Aitken JB, Gwee YY, Lim ZJ, Liu M, Singharay AM, Wong PF, Lay PA.

Chemistry. 2013 Mar 11;19(11):3609-19. doi: 10.1002/chem.201203127. Epub 2013 Jan 30.

PMID:
23361836
33.

FTIR imaging of brain tissue reveals crystalline creatine deposits are an ex vivo marker of localized ischemia during murine cerebral malaria: general implications for disease neurochemistry.

Hackett MJ, Lee J, El-Assaad F, McQuillan JA, Carter EA, Grau GE, Hunt NH, Lay PA.

ACS Chem Neurosci. 2012 Dec 19;3(12):1017-24. doi: 10.1021/cn300093g. Epub 2012 Sep 11.

34.

X-ray-induced photo-chemistry and X-ray absorption spectroscopy of biological samples.

George GN, Pickering IJ, Pushie MJ, Nienaber K, Hackett MJ, Ascone I, Hedman B, Hodgson KO, Aitken JB, Levina A, Glover C, Lay PA.

J Synchrotron Radiat. 2012 Nov;19(Pt 6):875-86. doi: 10.1107/S090904951203943X. Epub 2012 Oct 18.

35.

Synthesis and characterization of a chromium(V) cis-1,2-cyclohexanediolato complex: a model of reactive intermediates in chromium-induced cancers.

Bartholomäus R, Harms K, Levina A, Lay PA.

Inorg Chem. 2012 Nov 5;51(21):11238-40. doi: 10.1021/ic301900q. Epub 2012 Oct 17.

PMID:
23075053
36.

Hans C. Freeman preface.

Lay PA, Hambley TW.

J Inorg Biochem. 2012 Oct;115:113. doi: 10.1016/j.jinorgbio.2012.09.010. No abstract available.

PMID:
23026017
37.

Synchrotron radiation induced X-ray emission studies of the antioxidant mechanism of the organoselenium drug ebselen.

Aitken JB, Lay PA, Duong TT, Aran R, Witting PK, Harris HH, Lai B, Vogt S, Giles GI.

J Biol Inorg Chem. 2012 Apr;17(4):589-98. doi: 10.1007/s00775-012-0879-y. Epub 2012 Feb 11.

PMID:
22327627
38.

Metal-based anti-diabetic drugs: advances and challenges.

Levina A, Lay PA.

Dalton Trans. 2011 Nov 28;40(44):11675-86. doi: 10.1039/c1dt10380f. Epub 2011 Jul 13. Review.

PMID:
21750828
39.

Chemical alterations to murine brain tissue induced by formalin fixation: implications for biospectroscopic imaging and mapping studies of disease pathogenesis.

Hackett MJ, McQuillan JA, El-Assaad F, Aitken JB, Levina A, Cohen DD, Siegele R, Carter EA, Grau GE, Hunt NH, Lay PA.

Analyst. 2011 Jul 21;136(14):2941-52. doi: 10.1039/c0an00269k. Epub 2011 May 31.

PMID:
21629894
40.

Studies on the biotransformations and biodistributions of metal-containing drugs using X-ray absorption spectroscopy.

Aitken JB, Levina A, Lay PA.

Curr Top Med Chem. 2011;11(5):553-71. Review.

PMID:
21189127
41.
42.

Silicon nitride as a versatile growth substrate for microspectroscopic imaging and mapping of individual cells.

Carter EA, Rayner BS, McLeod AI, Wu LE, Marshall CP, Levina A, Aitken JB, Witting PK, Lai B, Cai Z, Vogt S, Lee YC, Chen CI, Tobin MJ, Harris HH, Lay PA.

Mol Biosyst. 2010 Jul;6(7):1316-22. doi: 10.1039/c001499k. Epub 2010 May 6.

PMID:
20445927
43.

Imaging metals in proteins by combining electrophoresis with rapid x-ray fluorescence mapping.

Finney L, Chishti Y, Khare T, Giometti C, Levina A, Lay PA, Vogt S.

ACS Chem Biol. 2010 Jun 18;5(6):577-87. doi: 10.1021/cb1000263.

PMID:
20392082
44.

Characterization of a ruthenium(III)/NAMI-A adduct with bovine serum albumin that exhibits a high anti-metastatic activity.

Liu M, Lim ZJ, Gwee YY, Levina A, Lay PA.

Angew Chem Int Ed Engl. 2010 Feb 22;49(9):1661-4. doi: 10.1002/anie.200906079. No abstract available.

PMID:
20127775
45.

Inhibition of experimental colorectal cancer and reduction in renal and gastrointestinal toxicities by copper-indomethacin in rats.

Bonin AM, Yáñez JA, Fukuda C, Teng XW, Dillon CT, Hambley TW, Lay PA, Davies NM.

Cancer Chemother Pharmacol. 2010 Sep;66(4):755-64. doi: 10.1007/s00280-009-1220-5. Epub 2009 Dec 25.

PMID:
20035423
46.

Recent developments in ruthenium anticancer drugs.

Levina A, Mitra A, Lay PA.

Metallomics. 2009 Nov;1(6):458-70. doi: 10.1039/b904071d. Epub 2009 Aug 13. Review.

PMID:
21305154
47.

Vibrational spectroscopic mapping and imaging of tissues and cells.

Carter EA, Tam KK, Armstrong RS, Lay PA.

Biophys Rev. 2009 Jul;1(2):95-103. doi: 10.1007/s12551-009-0012-9. Epub 2009 Jun 23. Review.

48.

Multiple protective activities of neuroglobin in cultured neuronal cells exposed to hypoxia re-oxygenation injury.

Duong TT, Witting PK, Antao ST, Parry SN, Kennerson M, Lai B, Vogt S, Lay PA, Harris HH.

J Neurochem. 2009 Mar;108(5):1143-54. doi: 10.1111/j.1471-4159.2008.05846.x. Epub 2009 Jan 20.

49.

A potential role for protein tyrosine phosphatase inhibition by a RuIII-edta complex (edta = ethylenediaminetetraacetate) in its biological activity.

Chatterjee D, Mitra A, Levina A, Lay PA.

Chem Commun (Camb). 2008 Jul 7;(25):2864-6. doi: 10.1039/b803261k. Epub 2008 May 28.

PMID:
18566706
50.

Reactivity of chromium(III) nutritional supplements in biological media: an X-ray absorption spectroscopic study.

Nguyen A, Mulyani I, Levina A, Lay PA.

Inorg Chem. 2008 May 19;47(10):4299-309. doi: 10.1021/ic7024389. Epub 2008 Apr 23.

PMID:
18433095

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