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Items: 1 to 50 of 60

1.

Promoter orientation of the immunomodulatory Bacteroides fragilis capsular polysaccharide A (PSA) is off in individuals with inflammatory bowel disease (IBD).

Blandford LE, Johnston EL, Sanderson JD, Wade WG, Lax AJ.

Gut Microbes. 2019 Feb 7:1-9. doi: 10.1080/19490976.2018.1560755. [Epub ahead of print]

PMID:
30732524
2.

G-Alpha Subunit Abundance and Activity Differentially Regulate β-Catenin Signaling.

Banu A, Liu KJ, Lax AJ, Grigoriadis AE.

Mol Cell Biol. 2019 Feb 15;39(5). pii: e00422-18. doi: 10.1128/MCB.00422-18. Print 2019 Mar 1.

3.

The actions of Pasteurella multocida toxin on neuronal cells.

Surguy SM, Duricki DA, Reilly JM, Lax AJ, Robbins J.

Neuropharmacology. 2014 Feb;77:9-18. doi: 10.1016/j.neuropharm.2013.09.005. Epub 2013 Sep 18.

4.

Modification of heterotrimeric G-proteins in Swiss 3T3 cells stimulated with Pasteurella multocida toxin.

Babb RC, Homer KA, Robbins J, Lax AJ.

PLoS One. 2012;7(11):e47188. doi: 10.1371/journal.pone.0047188. Epub 2012 Nov 5.

5.

Histidine Residues at the Active Site of the Pasteurella multocida Toxin.

Pullinger GD, Lax AJ.

Open Biochem J. 2007;1:7-11. doi: 10.2174/1874091X00701010007. Epub 2007 Jun 15.

6.

New genotoxin shows diversity of bacterial attack mechanisms.

Lax AJ.

Trends Mol Med. 2007 Mar;13(3):91-3. Epub 2007 Jan 17. Review.

PMID:
17234453
7.

Opinion: Bacterial toxins and cancer--a case to answer?

Lax AJ.

Nat Rev Microbiol. 2005 Apr;3(4):343-9. Review.

PMID:
15806096
8.

Identification and characterization of the Pasteurella multocida toxin translocation domain.

Baldwin MR, Lakey JH, Lax AJ.

Mol Microbiol. 2004 Oct;54(1):239-50.

9.

The pasteurella multocida toxin interacts with signalling pathways to perturb cell growth and differentiation.

Lax AJ, Pullinger GD, Baldwin MR, Harmey D, Grigoriadis AE, Lakey JH.

Int J Med Microbiol. 2004 Apr;293(7-8):505-12. Review.

PMID:
15149025
10.

Regulation of osteoblast differentiation by Pasteurella multocida toxin (PMT): a role for Rho GTPase in bone formation.

Harmey D, Stenbeck G, Nobes CD, Lax AJ, Grigoriadis AE.

J Bone Miner Res. 2004 Apr;19(4):661-70. Epub 2004 Jan 5.

11.

The Pasteurella multocida toxin is encoded within a lysogenic bacteriophage.

Pullinger GD, Bevir T, Lax AJ.

Mol Microbiol. 2004 Jan;51(1):255-69.

12.

Pasteurella multocida toxin facilitates inositol phosphate formation by bombesin through tyrosine phosphorylation of G alpha q.

Baldwin MR, Pullinger GD, Lax AJ.

J Biol Chem. 2003 Aug 29;278(35):32719-25. Epub 2003 Jun 10.

13.

How bacteria could cause cancer: one step at a time.

Lax AJ, Thomas W.

Trends Microbiol. 2002 Jun;10(6):293-9. Review.

PMID:
12088666
14.

Role of the dermonecrotic toxin of Bordetella bronchiseptica in the pathogenesis of respiratory disease in swine.

Brockmeier SL, Register KB, Magyar T, Lax AJ, Pullinger GD, Kunkle RA.

Infect Immun. 2002 Feb;70(2):481-90.

15.

Localization of functional domains of the mitogenic toxin of Pasteurella multocida.

Pullinger GD, Sowdhamini R, Lax AJ.

Infect Immun. 2001 Dec;69(12):7839-50.

16.
17.

Cytotoxic necrotizing factor from Escherichia coli induces RhoA-dependent expression of the cyclooxygenase-2 Gene.

Thomas W, Ascott ZK, Harmey D, Slice LW, Rozengurt E, Lax AJ.

Infect Immun. 2001 Nov;69(11):6839-45.

19.

The pathological effect of the Bordetella dermonecrotic toxin in mice.

Magyar T, Glávits R, Pullinger GD, Lax AJ.

Acta Vet Hung. 2000;48(4):397-406.

PMID:
11402657
20.

Lysostaphin expression in mammary glands confers protection against staphylococcal infection in transgenic mice.

Kerr DE, Plaut K, Bramley AJ, Williamson CM, Lax AJ, Moore K, Wells KD, Wall RJ.

Nat Biotechnol. 2001 Jan;19(1):66-70.

PMID:
11135555
21.

Reduced pH causes structural changes in the potent mitogenic toxin of Pasteurella multocida.

Smyth MG, Sumner IG, Lax AJ.

FEMS Microbiol Lett. 1999 Nov 1;180(1):15-20.

22.

Activity of the mitogenic Pasteurella multocida toxin requires an essential C-terminal residue.

Ward PN, Miles AJ, Sumner IG, Thomas LH, Lax AJ.

Infect Immun. 1998 Dec;66(12):5636-42.

23.
24.

Identification of restriction barriers in Pasteurella multocida.

Hoskins IC, Lax AJ.

FEMS Microbiol Lett. 1997 Nov 15;156(2):223-6.

26.

Nasal infection with Pasteurella multocida causes proliferation of bladder epithelium in gnotobiotic pigs.

Hoskins IC, Thomas LH, Lax AJ.

Vet Rec. 1997 Jan 4;140(1):22. No abstract available.

PMID:
9004479
27.

Cloning, expression, and molecular characterization of the dermonecrotic toxin gene of Bordetella spp.

Pullinger GD, Adams TE, Mullan PB, Garrod TI, Lax AJ.

Infect Immun. 1996 Oct;64(10):4163-71.

28.

Constitutive expression of Pasteurella multocida toxin.

Hoskins IC, Lax AJ.

FEMS Microbiol Lett. 1996 Aug 1;141(2-3):189-93.

PMID:
8768521
29.

The Salmonella virulence plasmid enhances Salmonella-induced lysis of macrophages and influences inflammatory responses.

Guilloteau LA, Wallis TS, Gautier AV, MacIntyre S, Platt DJ, Lax AJ.

Infect Immun. 1996 Aug;64(8):3385-93.

30.
32.

The Salmonella dublin virulence plasmid does not modulate early T-cell responses in mice.

Guilloteau LA, Lax AJ, MacIntyre S, Wallis TS.

Infect Immun. 1996 Jan;64(1):222-9.

33.
34.

Current perspectives in salmonellosis.

Lax AJ, Barrow PA, Jones PW, Wallis TS.

Br Vet J. 1995 Jul-Aug;151(4):351-77. Review.

PMID:
7552193
35.
36.

Development of a probe and PCR primers specific to the virulence plasmid of Salmonella enteritidis.

Wood MW, Mahon J, Lax AJ.

Mol Cell Probes. 1994 Dec;8(6):473-9.

PMID:
7700269
37.

Mutation of a putative ADP-ribosylation motif in the Pasteurella multocida toxin does not affect mitogenic activity.

Ward PN, Higgins TE, Murphy AC, Mullan PB, Rozengurt E, Lax AJ.

FEBS Lett. 1994 Mar 28;342(1):81-4.

38.

Expression of the lysostaphin gene of Staphylococcus simulans in a eukaryotic system.

Williamson CM, Bramley AJ, Lax AJ.

Appl Environ Microbiol. 1994 Mar;60(3):771-6.

39.

Regulation of spvR, the positive regulatory gene of Salmonella plasmid virulence genes.

Spink JM, Pullinger GD, Wood MW, Lax AJ.

FEMS Microbiol Lett. 1994 Feb 1;116(1):113-21.

PMID:
8132151
41.

Molecular analysis of spv virulence genes of the Salmonella virulence plasmids.

Gulig PA, Danbara H, Guiney DG, Lax AJ, Norel F, Rhen M.

Mol Microbiol. 1993 Mar;7(6):825-30. Review.

PMID:
8483415
42.
43.

Pasteurella multocida toxin is a potent inducer of anchorage-independent cell growth.

Higgins TE, Murphy AC, Staddon JM, Lax AJ, Rozengurt E.

Proc Natl Acad Sci U S A. 1992 May 15;89(10):4240-4.

44.

Pasteurella multocida toxin, a potent mitogen, increases inositol 1,4,5-trisphosphate and mobilizes Ca2+ in Swiss 3T3 cells.

Staddon JM, Barker CJ, Murphy AC, Chanter N, Lax AJ, Michell RH, Rozengurt E.

J Biol Chem. 1991 Mar 15;266(8):4840-7.

45.

Sequence analysis of the potent mitogenic toxin of Pasteurella multocida.

Lax AJ, Chanter N, Pullinger GD, Higgins T, Staddon JM, Rozengurt E.

FEBS Lett. 1990 Dec 17;277(1-2):59-64.

46.
47.

Identification of proteins expressed by the essential virulence region of the Salmonella dublin plasmid.

Williamson CM, Pullinger GD, Lax AJ.

Microb Pathog. 1990 Jul;9(1):61-6.

PMID:
2077345
48.

The virulence plasmid of Salmonella dublin: detailed restriction map and analysis by transposon mutagenesis.

Lax AJ, Pullinger GD, Baird GD, Williamson CM.

J Gen Microbiol. 1990 Jun;136(6):1117-23.

PMID:
2166770
49.

Cloning of the toxin gene from Pasteurella multocida and its role in atrophic rhinitis.

Lax AJ, Chanter N.

J Gen Microbiol. 1990 Jan;136(1):81-7.

PMID:
2351955
50.

Pasteurella multocida toxin: potent mitogen for cultured fibroblasts.

Rozengurt E, Higgins T, Chanter N, Lax AJ, Staddon JM.

Proc Natl Acad Sci U S A. 1990 Jan;87(1):123-7.

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