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Items: 1 to 50 of 179

1.

From the Cover: Fenretinide, Troglitazone, and Elmiron Add to Weight of Evidence Support for Hemangiosarcoma Mode-of-Action From Studies in Mice.

Cook JC, Obert LA, Koza-Taylor P, Coskran TM, Opsahl AC, Ziemek D, Roy M, Qian J, Lawton MP, Criswell KA.

Toxicol Sci. 2018 Jan 1;161(1):58-75. doi: 10.1093/toxsci/kfx195.

PMID:
28973697
2.

Use of Rat Primary Mesenteric Cells for the Prediction of PDE4 Inhibitor Drug-Induced Vascular Injury.

Gosink MM, Chapin RE, Wilkie D, Davenport S, Kumpf SW, Enerson BE, Houle C, Koza-Taylor P, Wisialowski TA, Lawton MP.

Toxicol Sci. 2017 Sep 1;159(1):42-49. doi: 10.1093/toxsci/kfx113.

PMID:
28903491
3.

Nonclinical safety biomarkers of drug-induced vascular injury: current status and blueprint for the future.

Mikaelian I, Cameron M, Dalmas DA, Enerson BE, Gonzalez RJ, Guionaud S, Hoffmann PK, King NM, Lawton MP, Scicchitano MS, Smith HW, Thomas RA, Weaver JL, Zabka TS; Vascular Injury Working Group of the Predictive Safety Consortium.

Toxicol Pathol. 2014 Jun;42(4):635-57. doi: 10.1177/0192623314525686. Epub 2014 Apr 28.

PMID:
24777748
4.

The role of eNOS phosphorylation in causing drug-induced vascular injury.

Tobin GA, Zhang J, Goodwin D, Stewart S, Xu L, Knapton A, González C, Bancos S, Zhang L, Lawton MP, Enerson BE, Weaver JL.

Toxicol Pathol. 2014 Jun;42(4):709-24. doi: 10.1177/0192623314522885. Epub 2014 Apr 3.

PMID:
24705881
5.

Hemodynamic correlates of drug-induced vascular injury in the rat using high-frequency ultrasound imaging.

Swanson TA, Conte T, Deeley B, Portugal S, Kreeger JM, Obert LA, Joseph EC, Wisialowski TA, Sokolowski SA, Rief C, Nugent P, Lawton MP, Enerson BE.

Toxicol Pathol. 2014 Jun;42(4):784-91. doi: 10.1177/0192623314525687. Epub 2014 Mar 26.

PMID:
24670818
6.

Analysis of changes in hepatic gene expression in a murine model of tolerance to acetaminophen hepatotoxicity (autoprotection).

O'Connor MA, Koza-Taylor P, Campion SN, Aleksunes LM, Gu X, Enayetallah AE, Lawton MP, Manautou JE.

Toxicol Appl Pharmacol. 2014 Jan 1;274(1):156-67. doi: 10.1016/j.taap.2013.09.025. Epub 2013 Oct 11.

7.

Assessment of 180┬░ rotation of the choroid as a novel surgical treatment for age-related macular degeneration.

Lee E, Singh MS, Jones HE, Ahmed B, Andolina IM, Clements JT, Luong V, Munro PM, Lawton MP, Grieve KL, Aylward GW, Sillito AM, MacLaren RE.

Invest Ophthalmol Vis Sci. 2012 May 4;53(6):2523-32. doi: 10.1167/iovs.11-8674.

PMID:
22427591
8.

Identification and elucidation of the biology of adverse events: the challenges of safety assessment and translational medicine.

Turteltaub KW, Davis MA, Burns-Naas LA, Lawton MP, Clark AM, Reynolds JA.

Clin Cancer Res. 2011 Nov 1;17(21):6641-5. doi: 10.1158/1078-0432.CCR-11-1106.

9.

Increased serum enzyme levels associated with kupffer cell reduction with no signs of hepatic or skeletal muscle injury.

Radi ZA, Koza-Taylor PH, Bell RR, Obert LA, Runnels HA, Beebe JS, Lawton MP, Sadis S.

Am J Pathol. 2011 Jul;179(1):240-7. doi: 10.1016/j.ajpath.2011.03.029. Epub 2011 May 13.

10.

Effects of modulating in vivo nitric oxide production on the incidence and severity of PDE4 inhibitor-induced vascular injury in Sprague-Dawley rats.

Sheth CM, Enerson BE, Peters D, Lawton MP, Weaver JL.

Toxicol Sci. 2011 Jul;122(1):7-15. doi: 10.1093/toxsci/kfr082. Epub 2011 Apr 16.

PMID:
21498876
11.

The role of hypoxia in 2-butoxyethanol-induced hemangiosarcoma.

Laifenfeld D, Gilchrist A, Drubin D, Jorge M, Eddy SF, Frushour BP, Ladd B, Obert LA, Gosink MM, Cook JC, Criswell K, Somps CJ, Koza-Taylor P, Elliston KO, Lawton MP.

Toxicol Sci. 2010 Jan;113(1):254-66. doi: 10.1093/toxsci/kfp213. Epub 2009 Oct 7.

12.

Differential gene expression in mouse liver associated with the hepatoprotective effect of clofibrate.

Moffit JS, Koza-Taylor PH, Holland RD, Thibodeau MS, Beger RD, Lawton MP, Manautou JE.

Toxicol Appl Pharmacol. 2007 Jul 15;222(2):169-79. Epub 2007 May 3.

13.

Symptoms, affects, and self-rated health: evidence for a subjective trajectory of health.

Winter L, Lawton MP, Langston CA, Ruckdeschel K, Sando R.

J Aging Health. 2007 Jun;19(3):453-69.

PMID:
17496244
14.

Three-dimensional quantitative structure-activity relationship analysis of human CYP51 inhibitors.

Ekins S, Mankowski DC, Hoover DJ, Lawton MP, Treadway JL, Harwood HJ Jr.

Drug Metab Dispos. 2007 Mar;35(3):493-500. Epub 2006 Dec 28. Erratum in: Drug Metab Dispos. 2007 Jul;35(7):1246.

15.

Pathway analysis using random forests classification and regression.

Pang H, Lin A, Holford M, Enerson BE, Lu B, Lawton MP, Floyd E, Zhao H.

Bioinformatics. 2006 Aug 15;22(16):2028-36. Epub 2006 Jun 29.

PMID:
16809386
16.

Acute drug-induced vascular injury in beagle dogs: pathology and correlating genomic expression.

Enerson BE, Lin A, Lu B, Zhao H, Lawton MP, Floyd E.

Toxicol Pathol. 2006;34(1):27-32.

PMID:
16507541
17.

VAT on veterinary prescriptions.

Lawton MP.

Vet Rec. 2005 Oct 8;157(15):456; discussion 456. No abstract available.

PMID:
16215256
18.

Environmental correlates to behavioral health outcomes in Alzheimer's special care units.

Zeisel J, Silverstein NM, Hyde J, Levkoff S, Lawton MP, Holmes W.

Gerontologist. 2003 Oct;43(5):697-711.

PMID:
14570966
19.

Preferences for prolonging life: a prospect theory approach.

Winter L, Lawton MP, Ruckdeschel K.

Int J Aging Hum Dev. 2003;56(2):155-70.

PMID:
14533855
20.

Motivation in later life: personal projects and well-being.

Lawton MP, Moss MS, Winter L, Hoffman C.

Psychol Aging. 2002 Dec;17(4):539-47.

PMID:
12507352
21.

The Therapeutic Environment Screening Survey for Nursing Homes (TESS-NH): an observational instrument for assessing the physical environment of institutional settings for persons with dementia.

Sloane PD, Mitchell CM, Weisman G, Zimmerman S, Foley KM, Lynn M, Calkins M, Lawton MP, Teresi J, Grant L, Lindeman D, Montgomery R.

J Gerontol B Psychol Sci Soc Sci. 2002 Mar;57(2):S69-78.

PMID:
11867668
22.

The physical environment of the person with Alzheimer's disease.

Lawton MP.

Aging Ment Health. 2001 May;5 Suppl 1:S56-64.

PMID:
11513499
23.

An overview of the social and behavioral consequences of Alzheimer's disease.

Pearlin LI, Harrington C, Lawton MP, Montgomery RJ, Zarit SH.

Aging Ment Health. 2001 May;5 Suppl 1:S3-6. No abstract available.

PMID:
11513495
24.

Valuation of life: a concept and a scale.

Lawton MP, Moss M, Hoffman C, Kleban MH, Ruckdeschel K, Winter L.

J Aging Health. 2001 Feb;13(1):3-31.

PMID:
11503845
25.

Burring cheek teeth in rabbits.

Davies RR, Lawton MP.

Vet Rec. 2001 Jun 2;148(22):700. No abstract available.

PMID:
11425262
26.

Characterization of transgenic mouse strains using six human hepatic cytochrome P450 probe substrates.

Mankowski DC, Lawton MP, Ekins S.

Xenobiotica. 2000 Aug;30(8):745-54.

PMID:
11037108
27.

Two transitions in daughters' caregiving careers.

Lawton MP, Moss M, Hoffman C, Perkinson M.

Gerontologist. 2000 Aug;40(4):437-48.

PMID:
10961033
28.

Reptiles and zoonoses.

Divers SJ, Lawton MP.

Vet Rec. 2000 Jul 22;147(4):116. No abstract available.

PMID:
10955889
29.

The psychosocial preferences of older adults: a pilot examination of content and structure.

Carpenter BD, Van Haitsma K, Ruckdeschel K, Lawton MP.

Gerontologist. 2000 Jun;40(3):335-48.

PMID:
10853528
30.

The relationship between external events and affect states in older people.

Winter L, Lawton MP, Casten RJ, Sando RL.

Int J Aging Hum Dev. 2000;50(2):85-96.

PMID:
10791610
31.

Professional environmental assessment procedure for special care units for elders with dementing illness and its relationship to the therapeutic environment screening schedule.

Lawton MP, Weisman GD, Sloane P, Norris-Baker C, Calkins M, Zimmerman SI.

Alzheimer Dis Assoc Disord. 2000 Jan-Mar;14(1):28-38.

PMID:
10718202
32.

Molecular cloning, expression, and characterization of CYP2D17 from cynomolgus monkey liver.

Mankowski DC, Laddison KJ, Christopherson PA, Ekins S, Tweedie DJ, Lawton MP.

Arch Biochem Biophys. 1999 Dec 1;372(1):189-96.

PMID:
10562433
33.

Affect and quality of life: objective and subjective.

Lawton MP, Winter L, Kleban MH, Ruckdeschel K.

J Aging Health. 1999 May;11(2):169-98.

PMID:
10558435
34.

Health, valuation of life, and the wish to live.

Lawton MP, Moss M, Hoffman C, Grant R, Ten Have T, Kleban MH.

Gerontologist. 1999 Aug;39(4):406-16.

PMID:
10495578
35.

Salience of positive and negative affect in the recognition of depression among elderly persons.

Harralson TL, Lawton MP.

Dialogues Clin Neurosci. 1999 Sep;1(2):129-33.

36.

Quality of life in chronic illness.

Lawton MP.

Gerontology. 1999 Jul-Aug;45(4):181-3. Review.

PMID:
10394072
37.

A stimulation-retreat special care unit for elders with dementing illness.

Lawton MP, Van Haitsma K, Klapper J, Kleban MH, Katz IR, Corn J.

Int Psychogeriatr. 1998 Dec;10(4):379-95.

PMID:
9924833
38.

Expression and characterization of canine cytochrome P450 2D15.

Roussel F, Duignan DB, Lawton MP, Obach RS, Strick CA, Tweedie DJ.

Arch Biochem Biophys. 1998 Sep 1;357(1):27-36.

PMID:
9721180
39.

Psychometric characteristics of the minimum data set II: validity.

Lawton MP, Casten R, Parmelee PA, Van Haitsma K, Corn J, Kleban MH.

J Am Geriatr Soc. 1998 Jun;46(6):736-44.

PMID:
9625190
40.

Psychometric characteristics of the minimum data set I: confirmatory factor analysis.

Casten R, Lawton MP, Parmelee PA, Kleban MH.

J Am Geriatr Soc. 1998 Jun;46(6):726-35.

PMID:
9625189
42.

The structure of depression among elderly institution residents: affective and somatic correlates of physical frailty.

Parmelee PA, Lawton MP, Katz IR.

J Gerontol A Biol Sci Med Sci. 1998 Mar;53(2):M155-62.

PMID:
9520923
43.

Methodological aspects of the study of streams of behavior in elders with dementing illness.

VanHaitsma K, Lawton MP, Kleban MH, Klapper J, Corn J.

Alzheimer Dis Assoc Disord. 1997 Dec;11(4):228-38.

PMID:
9437440
44.

Future society and technology.

Lawton MP.

Stud Health Technol Inform. 1998;48:12-22. Review. No abstract available.

PMID:
10186494
45.

Outcome measures for Alzheimer disease research: the continuum of domains to be measured.

Holmes D, Hurley A, Lawton MP.

Alzheimer Dis Assoc Disord. 1997;11 Suppl 6:175-8. No abstract available.

PMID:
9437463
46.

Assessing quality of life in Alzheimer disease research.

Lawton MP.

Alzheimer Dis Assoc Disord. 1997;11 Suppl 6:91-9.

PMID:
9437453
47.

Structural characteristics of flavin-containing monooxygenase genes one and two (FMO1 and FMO2).

Wyatt MK, Philpot RM, Carver G, Lawton MP, Nikbakht KN.

Drug Metab Dispos. 1996 Dec;24(12):1320-7.

PMID:
8971137
48.

Affective states in normal and depressed older people.

Lawton MP, Parmelee PA, Katz IR, Nesselroade J.

J Gerontol B Psychol Sci Soc Sci. 1996 Nov;51(6):P309-16.

PMID:
8931618
49.

Depression and medical illness in late life: report of a symposium.

Lyness JM, Bruce ML, Koenig HG, Parmelee PA, Schulz R, Lawton MP, Reynolds CF 3rd.

J Am Geriatr Soc. 1996 Feb;44(2):198-203.

PMID:
8576513
50.

Behavioral problems and interventions in Alzheimer's disease: research needs.

Lawton MP.

Int Psychogeriatr. 1996;8 Suppl 1:95-8. No abstract available.

PMID:
8934274

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