Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 92

1.

Identification of AHCY inhibitors using novel high-throughput mass spectrometry.

Uchiyama N, Dougan DR, Lawson JD, Kimura H, Matsumoto SI, Tanaka Y, Kawamoto T.

Biochem Biophys Res Commun. 2017 Sep 9;491(1):1-7. doi: 10.1016/j.bbrc.2017.05.107. Epub 2017 May 19.

PMID:
28533090
2.

Design, synthesis and optimization of 7-substituted-pyrazolo[4,3-b]pyridine ALK5 (activin receptor-like kinase 5) inhibitors.

Sabat M, Wang H, Scorah N, Lawson JD, Atienza J, Kamran R, Hixon MS, Dougan DR.

Bioorg Med Chem Lett. 2017 May 1;27(9):1955-1961. doi: 10.1016/j.bmcl.2017.03.026. Epub 2017 Mar 14.

PMID:
28359790
3.

MET Tyrosine Kinase Inhibition Enhances the Antitumor Efficacy of an HGF Antibody.

Farrell PJ, Matuszkiewicz J, Balakrishna D, Pandya S, Hixon MS, Kamran R, Chu S, Lawson JD, Okada K, Hori A, Mizutani A, Iwata H, de Jong R, Hibner B, Vincent P.

Mol Cancer Ther. 2017 Jul;16(7):1269-1278. doi: 10.1158/1535-7163.MCT-16-0771. Epub 2017 Mar 24.

4.

Clinical efficacy and safety of surface imaging guided radiosurgery (SIG-RS) in the treatment of benign skull base tumors.

Lau SK, Patel K, Kim T, Knipprath E, Kim GY, Cerviño LI, Lawson JD, Murphy KT, Sanghvi P, Carter BS, Chen CC.

J Neurooncol. 2017 Apr;132(2):307-312. doi: 10.1007/s11060-017-2370-7. Epub 2017 Jan 24.

PMID:
28120301
5.

Structure-based optimization of 1H-imidazole-2-carboxamides as Axl kinase inhibitors utilizing a Mer mutant surrogate.

Keung W, Boloor A, Brown J, Kiryanov A, Gangloff A, Lawson JD, Skene R, Hoffman I, Atienza J, Kahana J, De Jong R, Farrell P, Balakrishna D, Halkowycz P.

Bioorg Med Chem Lett. 2017 Feb 15;27(4):1099-1104. doi: 10.1016/j.bmcl.2016.12.024. Epub 2016 Dec 20.

PMID:
28082036
6.

Design, synthesis and optimization of novel Alk5 (activin-like kinase 5) inhibitors.

Wang H, Lawson JD, Scorah N, Kamran R, Hixon MS, Atienza J, Dougan DR, Sabat M.

Bioorg Med Chem Lett. 2016 Sep 1;26(17):4334-9. doi: 10.1016/j.bmcl.2016.07.030. Epub 2016 Jul 16.

PMID:
27460209
7.

Discovery of potent, reversible MetAP2 inhibitors via fragment based drug discovery and structure based drug design-Part 1.

Cheruvallath Z, Tang M, McBride C, Komandla M, Miura J, Ton-Nu T, Erikson P, Feng J, Farrell P, Lawson JD, Vanderpool D, Wu Y, Dougan DR, Plonowski A, Holub C, Larson C.

Bioorg Med Chem Lett. 2016 Jun 15;26(12):2774-2778. doi: 10.1016/j.bmcl.2016.04.073. Epub 2016 Apr 25.

PMID:
27155900
8.

Discovery of potent, reversible MetAP2 inhibitors via fragment based drug discovery and structure based drug design-Part 2.

McBride C, Cheruvallath Z, Komandla M, Tang M, Farrell P, Lawson JD, Vanderpool D, Wu Y, Dougan DR, Plonowski A, Holub C, Larson C.

Bioorg Med Chem Lett. 2016 Jun 15;26(12):2779-2783. doi: 10.1016/j.bmcl.2016.04.072. Epub 2016 Apr 25.

PMID:
27136719
9.

Fragment-based drug discovery of potent and selective MKK3/6 inhibitors.

Adams M, Kobayashi T, Lawson JD, Saitoh M, Shimokawa K, Bigi SV, Hixon MS, Smith CR, Tatamiya T, Goto M, Russo J, Grimshaw CE, Swann S.

Bioorg Med Chem Lett. 2016 Feb 1;26(3):1086-1089. doi: 10.1016/j.bmcl.2015.11.054. Epub 2015 Nov 17.

PMID:
26704264
10.

Sex-dependent effects of chronic psychosocial stress on myocardial sensitivity to ischemic injury.

Rorabaugh BR, Krivenko A, Eisenmann ED, Bui AD, Seeley S, Fry ME, Lawson JD, Stoner LE, Johnson BL, Zoladz PR.

Stress. 2015;18(6):645-53. doi: 10.3109/10253890.2015.1087505. Epub 2015 Oct 12.

PMID:
26458179
11.

Fragment-Based Discovery of a Small Molecule Inhibitor of Bruton's Tyrosine Kinase.

Smith CR, Dougan DR, Komandla M, Kanouni T, Knight B, Lawson JD, Sabat M, Taylor ER, Vu P, Wyrick C.

J Med Chem. 2015 Jul 23;58(14):5437-44. doi: 10.1021/acs.jmedchem.5b00734. Epub 2015 Jul 2.

PMID:
26087137
12.

Residence time and kinetic efficiency analysis of extracellular signal-regulated kinase 2 inhibitors.

Vanderpool D, Grimshaw CE, Lawson JD, Ermolieff J.

Anal Biochem. 2015 Mar 15;473:46-52. doi: 10.1016/j.ab.2014.12.008. Epub 2014 Dec 20.

PMID:
25535956
13.

Neurocognitive assessment following whole brain radiation therapy and radiosurgery for patients with cerebral metastases.

McDuff SG, Taich ZJ, Lawson JD, Sanghvi P, Wong ET, Barker FG 2nd, Hochberg FH, Loeffler JS, Warnke PC, Murphy KT, Mundt AJ, Carter BS, McDonald CR, Chen CC.

J Neurol Neurosurg Psychiatry. 2013 Dec;84(12):1384-91. doi: 10.1136/jnnp-2013-305166. Epub 2013 May 28. Review.

PMID:
23715918
14.

Frameless, real-time, surface imaging-guided radiosurgery: clinical outcomes for brain metastases.

Pan H, Cerviño LI, Pawlicki T, Jiang SB, Alksne J, Detorie N, Russell M, Carter BS, Murphy KT, Mundt AJ, Chen C, Lawson JD.

Neurosurgery. 2012 Oct;71(4):844-51.

PMID:
22989959
15.

Prospective study of functional bone marrow-sparing intensity modulated radiation therapy with concurrent chemotherapy for pelvic malignancies.

Liang Y, Bydder M, Yashar CM, Rose BS, Cornell M, Hoh CK, Lawson JD, Einck J, Saenz C, Fanta P, Mundt AJ, Bydder GM, Mell LK.

Int J Radiat Oncol Biol Phys. 2013 Feb 1;85(2):406-14. doi: 10.1016/j.ijrobp.2012.04.044. Epub 2012 Jun 9.

PMID:
22687195
16.

Clinical practice patterns of lung stereotactic body radiation therapy in the United States: a secondary analysis.

Pan H, Rose BS, Simpson DR, Mell LK, Mundt AJ, Lawson JD.

Am J Clin Oncol. 2013 Jun;36(3):269-72. doi: 10.1097/COC.0b013e3182467db3.

17.

A Back-to-Front Fragment-Based Drug Design Search Strategy Targeting the DFG-Out Pocket of Protein Tyrosine Kinases.

Iwata H, Oki H, Okada K, Takagi T, Tawada M, Miyazaki Y, Imamura S, Hori A, Lawson JD, Hixon MS, Kimura H, Miki H.

ACS Med Chem Lett. 2012 Feb 28;3(4):342-6. doi: 10.1021/ml3000403. eCollection 2012 Apr 12.

18.

Initial clinical experience with a frameless and maskless stereotactic radiosurgery treatment.

Cerviño LI, Detorie N, Taylor M, Lawson JD, Harry T, Murphy KT, Mundt AJ, Jiang SB, Pawlicki TA.

Pract Radiat Oncol. 2012 Jan-Mar;2(1):54-62. doi: 10.1016/j.prro.2011.04.005. Epub 2011 Dec 20.

PMID:
24674037
19.

Patterns of imaging failures in glioblastoma patients treated with chemoradiation: a retrospective study.

Pan H, Alksne J, Mundt AJ, Murphy KT, Cornell M, Kesari S, Lawson JD.

Med Oncol. 2012 Sep;29(3):2040-5. doi: 10.1007/s12032-011-0116-5. Epub 2011 Nov 23.

PMID:
22108847
20.

DNA damage response and repair: insights into strategies for radiation sensitization of gliomas.

Kesari S, Advani SJ, Lawson JD, Kahle KT, Ng K, Carter B, Chen CC.

Future Oncol. 2011 Nov;7(11):1335-46. doi: 10.2217/fon.11.111. Review.

21.

Leptomeningeal Metastasis from Appendiceal Adenocarcinoma: Case Report and Literature Review.

Mahta A, Kim RY, Fanta PT, Lawson JD, Kesari S.

J Gastrointest Cancer. 2012 Sep;43 Suppl 1:108-10. doi: 10.1007/s12029-011-9312-y. Review. No abstract available.

PMID:
21826409
22.

Frameless image-guided stereotactic body radiation therapy for lung tumors with 4-dimensional computed tomography or 4-dimensional positron emission tomography/ computed tomography.

Nath SK, Sandhu AP, Jensen L, Kim D, Bharne A, Nobiensky PD, Lawson JD, Fuster MM, Bazhenova L, Song WY, Mundt AJ.

Clin Lung Cancer. 2011 May;12(3):180-6. doi: 10.1016/j.cllc.2011.03.014. Epub 2011 Apr 24.

PMID:
21663861
23.

Gastric cancer.

Lawson JD, Sicklick JK, Fanta PT.

Curr Probl Cancer. 2011 May-Jun;35(3):97-127. doi: 10.1016/j.currproblcancer.2011.03.001. No abstract available.

PMID:
21635986
24.

Locoregional and distant failure following image-guided stereotactic body radiation for early-stage primary lung cancer.

Nath SK, Sandhu AP, Kim D, Bharne A, Nobiensky PD, Lawson JD, Fuster M, Bazhenova L, Song WY, Mundt AJ.

Radiother Oncol. 2011 Apr;99(1):12-7. doi: 10.1016/j.radonc.2011.02.006. Epub 2011 Mar 21.

PMID:
21429608
25.

A survey of stereotactic body radiotherapy use in the United States.

Pan H, Simpson DR, Mell LK, Mundt AJ, Lawson JD.

Cancer. 2011 Oct 1;117(19):4566-72. doi: 10.1002/cncr.26067. Epub 2011 Mar 15.

26.

Novel use of the Contura for high dose rate cranial brachytherapy.

Scanderbeg DJ, Alksne JF, Lawson JD, Murphy KT.

Med Dosim. 2011 Winter;36(4):344-6. doi: 10.1016/j.meddos.2010.08.001. Epub 2010 Dec 8.

PMID:
21144735
27.

Longitudinal MRI evidence for decreased survival among periventricular glioblastoma.

Young GS, Macklin EA, Setayesh K, Lawson JD, Wen PY, Norden AD, Drappatz J, Kesari S.

J Neurooncol. 2011 Aug;104(1):261-9. doi: 10.1007/s11060-010-0477-1. Epub 2010 Dec 5.

28.

Observed magnetic resonance imaging changes in pediatric patients treated with stereotactic radiosurgery for intracranial tumors.

Nath SK, Carmona R, Rose BS, Simpson DR, Russell M, Lawson JD, Mundt AJ, Murphy KT.

Childs Nerv Syst. 2011 Mar;27(3):399-406. doi: 10.1007/s00381-010-1288-6. Epub 2010 Oct 7.

29.

A survey of image-guided radiation therapy use in the United States.

Simpson DR, Lawson JD, Nath SK, Rose BS, Mundt AJ, Mell LK.

Cancer. 2010 Aug 15;116(16):3953-60. doi: 10.1002/cncr.25129.

30.

Markerless lung tumor tracking and trajectory reconstruction using rotational cone-beam projections: a feasibility study.

Lewis JH, Li R, Watkins WT, Lawson JD, Segars WP, Cerviño LI, Song WY, Jiang SB.

Phys Med Biol. 2010 May 7;55(9):2505-22. doi: 10.1088/0031-9155/55/9/006. Epub 2010 Apr 14.

PMID:
20393232
31.

Evaluation of automatic atlas-based lymph node segmentation for head-and-neck cancer.

Stapleford LJ, Lawson JD, Perkins C, Edelman S, Davis L, McDonald MW, Waller A, Schreibmann E, Fox T.

Int J Radiat Oncol Biol Phys. 2010 Jul 1;77(3):959-66. doi: 10.1016/j.ijrobp.2009.09.023. Epub 2010 Mar 16.

PMID:
20231069
32.

Frame-less and mask-less cranial stereotactic radiosurgery: a feasibility study.

Cerviño LI, Pawlicki T, Lawson JD, Jiang SB.

Phys Med Biol. 2010 Apr 7;55(7):1863-73. doi: 10.1088/0031-9155/55/7/005. Epub 2010 Mar 12.

PMID:
20224158
33.

Single-isocenter frameless intensity-modulated stereotactic radiosurgery for simultaneous treatment of multiple brain metastases: clinical experience.

Nath SK, Lawson JD, Simpson DR, Vanderspek L, Wang JZ, Alksne JF, Ciacci J, Mundt AJ, Murphy KT.

Int J Radiat Oncol Biol Phys. 2010 Sep 1;78(1):91-7. doi: 10.1016/j.ijrobp.2009.07.1726. Epub 2010 Jan 22.

PMID:
20096509
34.

Utilization of advanced imaging technologies for target delineation in radiation oncology.

Simpson DR, Lawson JD, Nath SK, Rose BS, Mundt AJ, Mell LK.

J Am Coll Radiol. 2009 Dec;6(12):876-83. doi: 10.1016/j.jacr.2009.08.006.

PMID:
19945044
35.

Dosimetric comparison of intensity-modulated radiosurgery and helical tomotherapy for the treatment of multiple intracranial metastases.

Vanderspek L, Bauman G, Wang JZ, Yartsev S, Ménard C, Cho YB, Mundt AJ, Lawson JD, Murphy KT.

Technol Cancer Res Treat. 2009 Oct;8(5):361-7.

PMID:
19754212
36.

Optically-guided frameless linac-based radiosurgery for brain metastases: clinical experience.

Nath SK, Lawson JD, Wang JZ, Simpson DR, Newman CB, Alksne JF, Mundt AJ, Murphy KT.

J Neurooncol. 2010 Mar;97(1):67-72. doi: 10.1007/s11060-009-9989-y. Epub 2009 Aug 23.

37.

Intracranial application of IMRT based radiosurgery to treat multiple or large irregular lesions and verification of infra-red frameless localization system.

Lawson JD, Wang JZ, Nath SK, Rice R, Pawlicki T, Mundt AJ, Murphy K.

J Neurooncol. 2010 Mar;97(1):59-66. doi: 10.1007/s11060-009-9987-0. Epub 2009 Aug 20.

38.

Percutaneous feeding tubes in patients with head and neck cancer: rethinking prophylactic placement for patients undergoing chemoradiation.

Lawson JD, Gaultney J, Saba N, Grist W, Davis L, Johnstone PA.

Am J Otolaryngol. 2009 Jul-Aug;30(4):244-9. doi: 10.1016/j.amjoto.2008.06.010. Epub 2009 Feb 6.

PMID:
19563935
39.

Initial clinical experience with frameless optically guided stereotactic radiosurgery/radiotherapy in pediatric patients.

Keshavarzi S, Meltzer H, Ben-Haim S, Newman CB, Lawson JD, Levy ML, Murphy K.

Childs Nerv Syst. 2009 Jul;25(7):837-44. doi: 10.1007/s00381-009-0840-8. Epub 2009 Mar 27.

40.

Multileaf collimator-based linear accelerator radiosurgery: five-year efficiency analysis.

Lawson JD, Fox T, Waller AF, Davis L, Crocker I.

J Am Coll Radiol. 2009 Mar;6(3):190-3. doi: 10.1016/j.jacr.2008.11.016.

PMID:
19248995
41.

Early clinical experience with kilovoltage image-guided radiation therapy for interfraction motion management.

Lawson JD, Fox T, Elder E, Nowlan A, Davis L, Keller J, Crocker I.

Med Dosim. 2008 Winter;33(4):268-74. doi: 10.1016/j.meddos.2007.06.002.

PMID:
18973853
42.

Early clinical results from chemoradiation with 5-fluorouracil and oxaliplatin for locally advanced rectal cancer.

Lawson JD, Kauh J, Koshy M, Staley C, Landry J.

Clin Colorectal Cancer. 2008 Sep;7(5):325-30. doi: 10.3816/CCC.2008.n.043.

PMID:
18794065
43.

Intensity modulated radiation therapy for retroperitoneal sarcoma: a case for dose escalation and organ at risk toxicity reduction.

Koshy M, Landry JC, Lawson JD, Staley CA, Esiashvili N, Howell R, Ghavidel S, Davis LW.

Sarcoma. 2003;7(3-4):137-48. doi: 10.1080/13577140310001644751.

44.
45.
46.

Quantification of dosimetric impact of implementation of on-board imaging (OBI) for IMRT treatment of head-and-neck malignancies.

Lawson JD, Elder E, Fox T, Davis L, Crocker I.

Med Dosim. 2007 Winter;32(4):287-94.

PMID:
17980830
47.
48.

Chemoradiotherapy for gastrointestinal cancers.

Rich TA, Crane C, Lawson JD, Landry J.

Curr Oncol Rep. 2005 May;7(3):196-202. Review.

PMID:
15847710
49.

DisProt: a database of protein disorder.

Vucetic S, Obradovic Z, Vacic V, Radivojac P, Peng K, Iakoucheva LM, Cortese MS, Lawson JD, Brown CJ, Sikes JG, Newton CD, Dunker AK.

Bioinformatics. 2005 Jan 1;21(1):137-40. Epub 2004 Aug 13.

PMID:
15310560
50.

Molecular dynamics analysis of structural factors influencing back door pi release in myosin.

Lawson JD, Pate E, Rayment I, Yount RG.

Biophys J. 2004 Jun;86(6):3794-803.

Supplemental Content

Loading ...
Support Center