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Items: 21


AI-Assisted Forward Modeling of Biological Structures.

Lawrimore J, Doshi A, Walker B, Bloom K.

Front Cell Dev Biol. 2019 Nov 14;7:279. doi: 10.3389/fcell.2019.00279. eCollection 2019.


The regulation of chromosome segregation via centromere loops.

Lawrimore J, Bloom K.

Crit Rev Biochem Mol Biol. 2019 Aug;54(4):352-370. doi: 10.1080/10409238.2019.1670130. Epub 2019 Oct 1.


Transient crosslinking kinetics optimize gene cluster interactions.

Walker B, Taylor D, Lawrimore J, Hult C, Adalsteinsson D, Bloom K, Forest MG.

PLoS Comput Biol. 2019 Aug 21;15(8):e1007124. doi: 10.1371/journal.pcbi.1007124. eCollection 2019 Aug.


Three-Dimensional Thermodynamic Simulation of Condensin as a DNA-Based Translocase.

Lawrimore J, He Y, Forest GM, Bloom K.

Methods Mol Biol. 2019;2004:291-318. doi: 10.1007/978-1-4939-9520-2_21.


tRNA Genes Affect Chromosome Structure and Function via Local Effects.

Hamdani O, Dhillon N, Hsieh TS, Fujita T, Ocampo J, Kirkland JG, Lawrimore J, Kobayashi TJ, Friedman B, Fulton D, Wu KY, Chereji RV, Oki M, Bloom K, Clark DJ, Rando OJ, Kamakaka RT.

Mol Cell Biol. 2019 Apr 2;39(8). pii: e00432-18. doi: 10.1128/MCB.00432-18. Print 2019 Apr 15.


Fork pausing allows centromere DNA loop formation and kinetochore assembly.

Cook DM, Bennett M, Friedman B, Lawrimore J, Yeh E, Bloom K.

Proc Natl Acad Sci U S A. 2018 Nov 13;115(46):11784-11789. doi: 10.1073/pnas.1806791115. Epub 2018 Oct 29.


Geometric partitioning of cohesin and condensin is a consequence of chromatin loops.

Lawrimore J, Doshi A, Friedman B, Yeh E, Bloom K.

Mol Biol Cell. 2018 Nov 1;29(22):2737-2750. doi: 10.1091/mbc.E18-02-0131. Epub 2018 Sep 12.


Changes in extreme events and the potential impacts on human health.

Bell JE, Brown CL, Conlon K, Herring S, Kunkel KE, Lawrimore J, Luber G, Schreck C, Smith A, Uejio C.

J Air Waste Manag Assoc. 2018 Apr;68(4):265-287. doi: 10.1080/10962247.2017.1401017.


RotoStep: A Chromosome Dynamics Simulator Reveals Mechanisms of Loop Extrusion.

Lawrimore J, Friedman B, Doshi A, Bloom K.

Cold Spring Harb Symp Quant Biol. 2017;82:101-109. doi: 10.1101/sqb.2017.82.033696. Epub 2017 Nov 22.


Enrichment of dynamic chromosomal crosslinks drive phase separation of the nucleolus.

Hult C, Adalsteinsson D, Vasquez PA, Lawrimore J, Bennett M, York A, Cook D, Yeh E, Forest MG, Bloom K.

Nucleic Acids Res. 2017 Nov 2;45(19):11159-11173. doi: 10.1093/nar/gkx741.


Microtubule dynamics drive enhanced chromatin motion and mobilize telomeres in response to DNA damage.

Lawrimore J, Barry TM, Barry RM, York AC, Friedman B, Cook DM, Akialis K, Tyler J, Vasquez P, Yeh E, Bloom K.

Mol Biol Cell. 2017 Jun 15;28(12):1701-1711. doi: 10.1091/mbc.E16-12-0846. Epub 2017 Apr 27.


Entropy gives rise to topologically associating domains.

Vasquez PA, Hult C, Adalsteinsson D, Lawrimore J, Forest MG, Bloom K.

Nucleic Acids Res. 2016 Jul 8;44(12):5540-9. doi: 10.1093/nar/gkw510. Epub 2016 Jun 2.


SUMO-Targeted Ubiquitin Ligase (STUbL) Slx5 regulates proteolysis of centromeric histone H3 variant Cse4 and prevents its mislocalization to euchromatin.

Ohkuni K, Takahashi Y, Fulp A, Lawrimore J, Au WC, Pasupala N, Levy-Myers R, Warren J, Strunnikov A, Baker RE, Kerscher O, Bloom K, Basrai MA.

Mol Biol Cell. 2016 Mar 9. pii: mbc.E15-12-0827. [Epub ahead of print]


ChromoShake: a chromosome dynamics simulator reveals that chromatin loops stiffen centromeric chromatin.

Lawrimore J, Aicher JK, Hahn P, Fulp A, Kompa B, Vicci L, Falvo M, Taylor RM 2nd, Bloom K.

Mol Biol Cell. 2016 Jan 1;27(1):153-66. doi: 10.1091/mbc.E15-08-0575. Epub 2015 Nov 4.


DNA loops generate intracentromere tension in mitosis.

Lawrimore J, Vasquez PA, Falvo MR, Taylor RM 2nd, Vicci L, Yeh E, Forest MG, Bloom K.

J Cell Biol. 2015 Aug 17;210(4):553-64. doi: 10.1083/jcb.201502046.


CLIMATE CHANGE. Possible artifacts of data biases in the recent global surface warming hiatus.

Karl TR, Arguez A, Huang B, Lawrimore JH, McMahon JR, Menne MJ, Peterson TC, Vose RS, Zhang HM.

Science. 2015 Jun 26;348(6242):1469-72. doi: 10.1126/science.aaa5632. Epub 2015 Jun 4.


Determining absolute protein numbers by quantitative fluorescence microscopy.

Verdaasdonk JS, Lawrimore J, Bloom K.

Methods Cell Biol. 2014;123:347-65. doi: 10.1016/B978-0-12-420138-5.00019-7.


Changes in weather and climate extremes: state of knowledge relevant to air and water quality in the United States.

Peterson TC, Karl TR, Kossin JP, Kunkel KE, Lawrimore JH, McMahon JR, Vose RS, Yin X.

J Air Waste Manag Assoc. 2014 Feb;64(2):184-97. Review.


A Sensitized Emission Based Calibration of FRET Efficiency for Probing the Architecture of Macromolecular Machines.

Joglekar A, Chen R, Lawrimore J.

Cell Mol Bioeng. 2013;6(4):369-382. Epub 2013 Jul 11.


Spindle assembly checkpoint proteins are positioned close to core microtubule attachment sites at kinetochores.

Varma D, Wan X, Cheerambathur D, Gassmann R, Suzuki A, Lawrimore J, Desai A, Salmon ED.

J Cell Biol. 2013 Sep 2;202(5):735-46. doi: 10.1083/jcb.201304197. Epub 2013 Aug 26.


Point centromeres contain more than a single centromere-specific Cse4 (CENP-A) nucleosome.

Lawrimore J, Bloom KS, Salmon ED.

J Cell Biol. 2011 Nov 14;195(4):573-82. doi: 10.1083/jcb.201106036.

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