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Items: 1 to 50 of 54

1.

Detection of microscopic diffusion anisotropy in human cortical gray matter in vivo with double diffusion encoding.

Lawrenz M, Finsterbusch J.

Magn Reson Med. 2019 Feb;81(2):1296-1306. doi: 10.1002/mrm.27451. Epub 2018 Sep 11.

PMID:
30206991
2.

Inflammasome-Independent Leukotriene B4 Production Drives Crystalline Silica-Induced Sterile Inflammation.

Hegde B, Bodduluri SR, Satpathy SR, Alghsham RS, Jala VR, Uriarte SM, Chung DH, Lawrenz MB, Haribabu B.

J Immunol. 2018 May 15;200(10):3556-3567. doi: 10.4049/jimmunol.1701504. Epub 2018 Apr 2.

PMID:
29610142
3.

Yersinia pestis Targets the Host Endosome Recycling Pathway during the Biogenesis of the Yersinia-Containing Vacuole To Avoid Killing by Macrophages.

Connor MG, Pulsifer AR, Chung D, Rouchka EC, Ceresa BK, Lawrenz MB.

MBio. 2018 Feb 20;9(1). pii: e01800-17. doi: 10.1128/mBio.01800-17.

4.

Impact of Gentamicin Concentration and Exposure Time on Intracellular Yersinia pestis.

VanCleave TT, Pulsifer AR, Connor MG, Warawa JM, Lawrenz MB.

Front Cell Infect Microbiol. 2017 Dec 11;7:505. doi: 10.3389/fcimb.2017.00505. eCollection 2017.

5.

Crystal structure of Yersinia pestis virulence factor YfeA reveals two polyspecific metal-binding sites.

Radka CD, DeLucas LJ, Wilson LS, Lawrenz MB, Perry RD, Aller SG.

Acta Crystallogr D Struct Biol. 2017 Jul 1;73(Pt 7):557-572. doi: 10.1107/S2059798317006349. Epub 2017 Jun 30.

6.

Zinc transporters YbtX and ZnuABC are required for the virulence of Yersinia pestis in bubonic and pneumonic plague in mice.

Bobrov AG, Kirillina O, Fosso MY, Fetherston JD, Miller MC, VanCleave TT, Burlison JA, Arnold WK, Lawrenz MB, Garneau-Tsodikova S, Perry RD.

Metallomics. 2017 Jun 21;9(6):757-772. doi: 10.1039/c7mt00126f.

7.

Host FIH-Mediated Asparaginyl Hydroxylation of Translocated Legionella pneumophila Effectors.

Price C, Merchant M, Jones S, Best A, Von Dwingelo J, Lawrenz MB, Alam N, Schueler-Furman O, Kwaik YA.

Front Cell Infect Microbiol. 2017 Mar 6;7:54. doi: 10.3389/fcimb.2017.00054. eCollection 2017.

8.

Microscopic diffusion anisotropy in the human brain: Age-related changes.

Lawrenz M, Brassen S, Finsterbusch J.

Neuroimage. 2016 Nov 1;141:313-325. doi: 10.1016/j.neuroimage.2016.07.031. Epub 2016 Jul 17.

PMID:
27436594
9.

Novel Synthesis of Kanamycin Conjugated Gold Nanoparticles with Potent Antibacterial Activity.

Payne JN, Waghwani HK, Connor MG, Hamilton W, Tockstein S, Moolani H, Chavda F, Badwaik V, Lawrenz MB, Dakshinamurthy R.

Front Microbiol. 2016 May 2;7:607. doi: 10.3389/fmicb.2016.00607. eCollection 2016.

10.

Yersinia pestis Requires Host Rab1b for Survival in Macrophages.

Connor MG, Pulsifer AR, Price CT, Abu Kwaik Y, Lawrenz MB.

PLoS Pathog. 2015 Oct 23;11(10):e1005241. doi: 10.1371/journal.ppat.1005241. eCollection 2015 Oct.

11.

Conventions and nomenclature for double diffusion encoding NMR and MRI.

Shemesh N, Jespersen SN, Alexander DC, Cohen Y, Drobnjak I, Dyrby TB, Finsterbusch J, Koch MA, Kuder T, Laun F, Lawrenz M, Lundell H, Mitra PP, Nilsson M, Özarslan E, Topgaard D, Westin CF.

Magn Reson Med. 2016 Jan;75(1):82-7. doi: 10.1002/mrm.25901. Epub 2015 Sep 29. Review.

PMID:
26418050
12.

Corrigendum: Cloud-based simulations on Google Exacycle reveal ligand modulation of GPCR activation pathways.

Kohlhoff KJ, Shukla D, Lawrenz M, Bowman GR, Konerding DE, Belov D, Altman RB, Pande VS.

Nat Chem. 2015 Sep;7(9):759. doi: 10.1038/nchem.2272. No abstract available.

PMID:
26291949
13.

A network of molecular switches controls the activation of the two-component response regulator NtrC.

Vanatta DK, Shukla D, Lawrenz M, Pande VS.

Nat Commun. 2015 Jun 15;6:7283. doi: 10.1038/ncomms8283.

PMID:
26073186
14.

Nanotechnology's Impact on Medicinal Chemistry.

Hamilton W, Modi T, Waghwani HK, Tockstein S, Payne J, Filani O, Badwaik V, Shah M, Webb C, Lawrenz MB, Dakshinamurthy R.

Mini Rev Med Chem. 2015 May 11. [Epub ahead of print]

PMID:
25963566
15.

Elucidating Ligand-Modulated Conformational Landscape of GPCRs Using Cloud-Computing Approaches.

Shukla D, Lawrenz M, Pande VS.

Methods Enzymol. 2015;557:551-72. doi: 10.1016/bs.mie.2014.12.007. Epub 2015 Mar 24. Review.

PMID:
25950981
16.

Development and evaluation of murine lung-specific disease models for Pseudomonas aeruginosa applicable to therapeutic testing.

Lawrenz MB, Biller AE, Cramer DE, Kraenzle JL, Sotsky JB, Vanover CD, Yoder-Himes DR, Pollard A, Warawa JM.

Pathog Dis. 2015 Jul;73(5). pii: ftv025. doi: 10.1093/femspd/ftv025. Epub 2015 Apr 9.

17.

Cloud computing approaches for prediction of ligand binding poses and pathways.

Lawrenz M, Shukla D, Pande VS.

Sci Rep. 2015 Jan 22;5:7918. doi: 10.1038/srep07918.

18.

Microscopic diffusion anisotropy in the human brain: reproducibility, normal values, and comparison with the fractional anisotropy.

Lawrenz M, Brassen S, Finsterbusch J.

Neuroimage. 2015 Apr 1;109:283-97. doi: 10.1016/j.neuroimage.2015.01.025. Epub 2015 Jan 13.

PMID:
25595503
19.

Intubation-mediated intratracheal (IMIT) instillation: a noninvasive, lung-specific delivery system.

Lawrenz MB, Fodah RA, Gutierrez MG, Warawa J.

J Vis Exp. 2014 Nov 17;(93):e52261. doi: 10.3791/52261.

20.

Improving the Th1 cellular efficacy of the lead Yersinia pestis rF1-V subunit vaccine using SA-4-1BBL as a novel adjuvant.

Dinc G, Pennington JM, Yolcu ES, Lawrenz MB, Shirwan H.

Vaccine. 2014 Sep 3;32(39):5035-40. doi: 10.1016/j.vaccine.2014.07.015. Epub 2014 Jul 18.

PMID:
25045812
21.

Gold nanoparticles: various methods of synthesis and antibacterial applications.

Shah M, Badwaik V, Kherde Y, Waghwani HK, Modi T, Aguilar ZP, Rodgers H, Hamilton W, Marutharaj T, Webb C, Lawrenz MB, Dakshinamurthy R.

Front Biosci (Landmark Ed). 2014 Jun 1;19:1320-44. Review.

PMID:
24896353
22.

Mapping measures of microscopic diffusion anisotropy in human brain white matter in vivo with double-wave-vector diffusion-weighted imaging.

Lawrenz M, Finsterbusch J.

Magn Reson Med. 2015 Feb;73(2):773-83. doi: 10.1002/mrm.25140. Epub 2014 Jan 27.

PMID:
24469974
23.

Cloud-based simulations on Google Exacycle reveal ligand modulation of GPCR activation pathways.

Kohlhoff KJ, Shukla D, Lawrenz M, Bowman GR, Konerding DE, Belov D, Altman RB, Pande VS.

Nat Chem. 2014 Jan;6(1):15-21. doi: 10.1038/nchem.1821. Epub 2013 Dec 15. Erratum in: Nat Chem. 2015 Sep;7(9):759.

24.

Bioluminescent imaging of bacteria during mouse infection.

Warawa JM, Lawrenz MB.

Methods Mol Biol. 2014;1098:169-81. doi: 10.1007/978-1-62703-718-1_14.

PMID:
24166377
25.

Acquisition of omptin reveals cryptic virulence function of autotransporter YapE in Yersinia pestis.

Lawrenz MB, Pennington J, Miller VL.

Mol Microbiol. 2013 Jul;89(2):276-87. doi: 10.1111/mmi.12273. Epub 2013 Jun 10.

26.

Development of bioluminescent bioreporters for in vitro and in vivo tracking of Yersinia pestis.

Sun Y, Connor MG, Pennington JM, Lawrenz MB.

PLoS One. 2012;7(10):e47123. doi: 10.1371/journal.pone.0047123. Epub 2012 Oct 11.

27.

Double-wave-vector diffusion-weighted imaging reveals microscopic diffusion anisotropy in the living human brain.

Lawrenz M, Finsterbusch J.

Magn Reson Med. 2013 Apr;69(4):1072-82. doi: 10.1002/mrm.24347. Epub 2012 Jun 18.

28.

Thermodynamic integration to predict host-guest binding affinities.

Lawrenz M, Wereszczynski J, Ortiz-Sánchez JM, Nichols SE, McCammon JA.

J Comput Aided Mol Des. 2012 May;26(5):569-76. doi: 10.1007/s10822-012-9542-5. Epub 2012 Feb 16.

29.

Independent-Trajectory Thermodynamic Integration: a practical guide to protein-drug binding free energy calculations using distributed computing.

Lawrenz M, Baron R, Wang Y, McCammon JA.

Methods Mol Biol. 2012;819:469-86. doi: 10.1007/978-1-61779-465-0_27.

PMID:
22183552
30.

Genetic and pharmacological targeting of TPL-2 kinase ameliorates experimental colitis: a potential target for the treatment of Crohn's disease?

Lawrenz M, Visekruna A, Kühl A, Schmidt N, Kaufmann SH, Steinhoff U.

Mucosal Immunol. 2012 Mar;5(2):129-39. doi: 10.1038/mi.2011.57. Epub 2011 Dec 7.

PMID:
22157885
31.

Expression during host infection and localization of Yersinia pestis autotransporter proteins.

Lenz JD, Lawrenz MB, Cotter DG, Lane MC, Gonzalez RJ, Palacios M, Miller VL.

J Bacteriol. 2011 Nov;193(21):5936-49. doi: 10.1128/JB.05877-11. Epub 2011 Aug 26.

32.

Effects of Biomolecular Flexibility on Alchemical Calculations of Absolute Binding Free Energies.

Lawrenz M, Baron R, Wang Y, McCammon JA.

J Chem Theory Comput. 2011 Jun 2;7(7):2224-2232.

33.

Detection of microscopic diffusion anisotropy on a whole-body MR system with double wave vector imaging.

Lawrenz M, Finsterbusch J.

Magn Reson Med. 2011 Nov;66(5):1405-15. doi: 10.1002/mrm.22934. Epub 2011 Apr 12.

34.

The dependence of the Yersinia pestis capsule on pathogenesis is influenced by the mouse background.

Weening EH, Cathelyn JS, Kaufman G, Lawrenz MB, Price P, Goldman WE, Miller VL.

Infect Immun. 2011 Feb;79(2):644-52. doi: 10.1128/IAI.00981-10. Epub 2010 Nov 29.

35.

Porous protein frameworks with unsaturated metal centers in sterically encumbered coordination sites.

Radford RJ, Lawrenz M, Nguyen PC, McCammon JA, Tezcan FA.

Chem Commun (Camb). 2011 Jan 7;47(1):313-5. doi: 10.1039/c0cc02168g. Epub 2010 Aug 25.

PMID:
20740227
36.

Double-wave-vector diffusion-weighting experiments with multiple concatenations at long mixing times.

Lawrenz M, Finsterbusch J.

J Magn Reson. 2010 Sep;206(1):112-9. doi: 10.1016/j.jmr.2010.06.016. Epub 2010 Jun 30.

PMID:
20638307
37.

Impact of calcium on N1 influenza neuraminidase dynamics and binding free energy.

Lawrenz M, Wereszczynski J, Amaro R, Walker R, Roitberg A, McCammon JA.

Proteins. 2010 Aug 15;78(11):2523-32. doi: 10.1002/prot.22761.

38.

Model systems to study plague pathogenesis and develop new therapeutics.

Lawrenz MB.

Front Microbiol. 2010 Nov 4;1:119. doi: 10.3389/fmicb.2010.00119. eCollection 2010.

39.

A tensor model and measures of microscopic anisotropy for double-wave-vector diffusion-weighting experiments with long mixing times.

Lawrenz M, Koch MA, Finsterbusch J.

J Magn Reson. 2010 Jan;202(1):43-56. doi: 10.1016/j.jmr.2009.09.015. Epub 2009 Oct 1.

PMID:
19854085
41.

Comparative expression analysis and characterization of 20S proteasomes in human intestinal tissues: The proteasome pattern as diagnostic tool for IBD patients.

Visekruna A, Joeris T, Schmidt N, Lawrenz M, Ritz JP, Buhr HJ, Steinhoff U.

Inflamm Bowel Dis. 2009 Apr;15(4):526-33. doi: 10.1002/ibd.20805.

PMID:
19067411
42.

A novel autotransporter adhesin is required for efficient colonization during bubonic plague.

Lawrenz MB, Lenz JD, Miller VL.

Infect Immun. 2009 Jan;77(1):317-26. doi: 10.1128/IAI.01206-08. Epub 2008 Oct 20.

43.

The Yersinia pestis autotransporter YapC mediates host cell binding, autoaggregation and biofilm formation.

Felek S, Lawrenz MB, Krukonis ES.

Microbiology. 2008 Jun;154(Pt 6):1802-12. doi: 10.1099/mic.0.2007/010918-0.

PMID:
18524935
44.

Comparative analysis of the regulation of rovA from the pathogenic yersiniae.

Lawrenz MB, Miller VL.

J Bacteriol. 2007 Aug;189(16):5963-75. Epub 2007 Jun 15.

45.

Quiescence and functional reprogramming of Epstein-Barr virus (EBV)-specific CD8+ T cells during persistent infection.

Dunne PJ, Belaramani L, Fletcher JM, Fernandez de Mattos S, Lawrenz M, Soares MV, Rustin MH, Lam EW, Salmon M, Akbar AN.

Blood. 2005 Jul 15;106(2):558-65. Epub 2005 Mar 29.

46.
47.

Invasin and beyond: regulation of Yersinia virulence by RovA.

Ellison DW, Lawrenz MB, Miller VL.

Trends Microbiol. 2004 Jun;12(6):296-300. Review.

PMID:
15165608
48.

Effect of complement component C3 deficiency on experimental Lyme borreliosis in mice.

Lawrenz MB, Wooten RM, Zachary JF, Drouin SM, Weis JJ, Wetsel RA, Norris SJ.

Infect Immun. 2003 Aug;71(8):4432-40.

49.

A plasmid-encoded nicotinamidase (PncA) is essential for infectivity of Borrelia burgdorferi in a mammalian host.

Purser JE, Lawrenz MB, Caimano MJ, Howell JK, Radolf JD, Norris SJ.

Mol Microbiol. 2003 May;48(3):753-64.

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