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Clinical Development of Novel Drug-Radiotherapy Combinations.

Ahmad SS, Crittenden MR, Tran PT, Kluetz PG, Blumenthal GM, Bulbeck H, Baird RD, Williams KJ, Illidge T, Hahn S, Lawrence TS, Spears PA, Walker AJ, Sharma RA.

Clin Cancer Res. 2018 Nov 29. pii: clincanres.2466.2018. doi: 10.1158/1078-0432.CCR-18-2466. [Epub ahead of print]


Enhancing the Radiation Response in KRAS Mutant Colorectal Cancers Using the c-Met Inhibitor Crizotinib.

Cuneo KC, Mehta RK, Kurapati H, Thomas DG, Lawrence TS, Nyati MK.

Transl Oncol. 2018 Nov 6;12(2):209-216. doi: 10.1016/j.tranon.2018.10.005. [Epub ahead of print]


Greater reduction in mid-treatment FDG-PET volume may be associated with worse survival in non-small cell lung cancer.

Kong FS, Li L, Wang W, Campbell J, Waller JL, Piert M, Gross M, Cheng M, Owen D, Stenmark M, Huang KC, Frey KA, Ten Haken RK, Lawrence TS.

Radiother Oncol. 2018 Oct 30. pii: S0167-8140(18)33518-7. doi: 10.1016/j.radonc.2018.10.006. [Epub ahead of print]


Significance of Perioperative Tests to Diagnose the Infection in Revision Total Shoulder Arthroplasty.

Ahmadi S, Lawrence TM, Sahota S, Schleck CD, Harmsen WS, Cofield RH, Sperling JW.

Arch Bone Jt Surg. 2018 Sep;6(5):359-364.


Treatment data and technical process challenges for practical big data efforts in radiation oncology.

Mayo CS, Phillips M, McNutt TR, Palta J, Dekker A, Miller RC, Xiao Y, Moran JM, Matuszak MM, Gabriel P, Ayan AS, Prisciandaro J, Thor M, Dixit N, Popple R, Killoran J, Kaleba E, Kantor M, Ruan D, Kapoor R, Kessler ML, Lawrence TS.

Med Phys. 2018 Oct;45(10):e793-e810. doi: 10.1002/mp.13114. Epub 2018 Sep 18.


MR Imaging Evaluation of Hepatocellular Carcinoma Treated with Stereotactic Body Radiation Therapy (SBRT): Long Term Imaging Follow-Up.

Mendiratta-Lala M, Masch W, Shankar PR, Hartman HE, Davenport MS, Schipper MJ, Maurino C, Cuneo KC, Lawrence TS, Owen D.

Int J Radiat Oncol Biol Phys. 2018 Sep 10. pii: S0360-3016(18)33729-5. doi: 10.1016/j.ijrobp.2018.09.004. [Epub ahead of print]


Acetabular Subchondral Bone Decortication and Its Role in the Outcome of Cemented Total Hip Replacement in Young Patients.

Garala K, Boutefnouchet T, Amblawaner K, Chahal G, Lawrence T.

Hip Pelvis. 2018 Sep;30(3):182-189. doi: 10.5371/hp.2018.30.3.182. Epub 2018 Sep 4.


No Sugar Added: A New Strategy to Inhibit Glioblastoma Receptor Tyrosine Kinases.

Wahl DR, Lawrence TS.

Clin Cancer Res. 2018 Sep 4. doi: 10.1158/1078-0432.CCR-18-2113. [Epub ahead of print]


Molecular dissection of plasmacytoid dendritic cell activation in vivo during a viral infection.

Tomasello E, Naciri K, Chelbi R, Bessou G, Fries A, Gressier E, Abbas A, Pollet E, Pierre P, Lawrence T, Vu Manh TP, Dalod M.

EMBO J. 2018 Oct 1;37(19). pii: e98836. doi: 10.15252/embj.201798836. Epub 2018 Aug 21.


Biobrane™ versus acticoat™ for the treatment of mid-dermal pediatric burns: a prospective randomized controlled pilot study.

Hyland EJ, D'Cruz R, Menon S, Harvey JG, La Hei E, Lawrence T, Waddell K, Nash M, Holland AJ.

Int J Burns Trauma. 2018 Jun 20;8(3):63-67. eCollection 2018.


Spatially explicit action research for coastal fisheries management.

Lawrence TN, Bhalla RS.

PLoS One. 2018 Jul 11;13(7):e0199841. doi: 10.1371/journal.pone.0199841. eCollection 2018.


Combining Perfusion and High B-value Diffusion MRI to Inform Prognosis and Predict Failure Patterns in Glioblastoma.

Wahl DR, Kim MM, Aryal MP, Hartman H, Lawrence TS, Schipper MJ, Parmar HA, Cao Y.

Int J Radiat Oncol Biol Phys. 2018 Nov 15;102(4):757-764. doi: 10.1016/j.ijrobp.2018.04.045. Epub 2018 Jun 2.


Unexpected cause of fever in a patient with untreated HIV.

Chhetri M, Miaskiewicz S, Lawrence TA, Kapetanos A.

BMJ Case Rep. 2018 Jul 3;2018. pii: bcr-2018-225087. doi: 10.1136/bcr-2018-225087.


The Natural History of Full-Thickness Rotator Cuff Tears in Randomized Controlled Trials: A Systematic Review and Meta-analysis.

Khatri C, Ahmed I, Parsons H, Smith NA, Lawrence TM, Modi CS, Drew SJ, Bhabra G, Parsons NR, Underwood M, Metcalfe AJ.

Am J Sports Med. 2018 Jun 1:363546518780694. doi: 10.1177/0363546518780694. [Epub ahead of print]


Casual Causality: Does Radiofrequency Ablation Really Prolong Survival After Treatment of Localized Hepatocellular Carcinoma?

Wahl DR, Schipper MJ, Parikh ND, Owen D, Lawrence TS.

J Clin Oncol. 2018 Aug 20;36(24):2559-2560. doi: 10.1200/JCO.2018.78.0882. Epub 2018 Jun 26. No abstract available.


Chaperone Activity and Dimerization Properties of Hsp90α and Hsp90β in Glucocorticoid Receptor Activation by the Multiprotein Hsp90/Hsp70-Dependent Chaperone Machinery.

Morishima Y, Mehta RK, Yoshimura M, Lau M, Southworth DR, Lawrence TS, Pratt WB, Nyati MK, Osawa Y.

Mol Pharmacol. 2018 Sep;94(3):984-991. doi: 10.1124/mol.118.112516. Epub 2018 Jun 25.


A pharmacokinetics phase 1 bioequivalence study of the trastuzumab biosimilar MYL-1401O vs. EU-trastuzumab and US-trastuzumab.

Waller CF, Vutikullird A, Lawrence TE, Shaw A, Liu MS, Baczkowski M, Sharma R, Barve A, Goyal P, Donnelly C, Sengupta N, Pennella EJ.

Br J Clin Pharmacol. 2018 Oct;84(10):2336-2343. doi: 10.1111/bcp.13689. Epub 2018 Jul 31.


A report of 3 cases of Exeter V40 Stem fracture and explanation of possible causes.

Garala K, Laios T, Lawrence T.

Hip Int. 2018 Nov;28(6):NP1-NP5. doi: 10.1177/1120700018780887. Epub 2018 Jun 15.


The contribution of DNA replication stress marked by high-intensity, pan-nuclear γH2AX staining to chemosensitization by CHK1 and WEE1 inhibitors.

Parsels LA, Parsels JD, Tanska DM, Maybaum J, Lawrence TS, Morgan MA.

Cell Cycle. 2018;17(9):1076-1086. doi: 10.1080/15384101.2018.1475827. Epub 2018 Jul 18.


Effectiveness and cost of radiofrequency ablation and stereotactic body radiotherapy for treatment of early-stage hepatocellular carcinoma: An analysis of SEER-medicare.

Parikh ND, Marshall VD, Green M, Lawrence TS, Razumilava N, Owen D, Singal AG, Feng M.

J Med Imaging Radiat Oncol. 2018 Oct;62(5):673-681. doi: 10.1111/1754-9485.12754. Epub 2018 Jun 7.


Carcass fabrication yields of beef steers supplemented zilpaterol hydrochloride and offered ad libitum or maintenance energy intake.

Schmitz AN, Walter LJ, Nichols WT, Hutcheson JP, Lawrence TE.

J Anim Sci. 2018 Jul 28;96(8):3173-3183. doi: 10.1093/jas/sky192.


A multiobjective Bayesian networks approach for joint prediction of tumor local control and radiation pneumonitis in nonsmall-cell lung cancer (NSCLC) for response-adapted radiotherapy.

Luo Y, McShan DL, Matuszak MM, Ray D, Lawrence TS, Jolly S, Kong FM, Ten Haken RK, El Naqa I.

Med Phys. 2018 Jun 4. doi: 10.1002/mp.13029. [Epub ahead of print]


Representing the Process of Inflammation as Key Events in Adverse Outcome Pathways.

Villeneuve DL, Landesmann B, Allavena P, Ashley N, Bal-Price A, Corsini E, Halappanavar S, Hussell T, Laskin D, Lawrence T, Nikolic-Paterson D, Pallardy M, Paini A, Pieters R, Roth R, Tschudi-Monnet F.

Toxicol Sci. 2018 Jun 1;163(2):346-352. doi: 10.1093/toxsci/kfy047.


CD8 Follicular T Cells Promote B Cell Antibody Class Switch in Autoimmune Disease.

Valentine KM, Davini D, Lawrence TJ, Mullins GN, Manansala M, Al-Kuhlani M, Pinney JM, Davis JK, Beaudin AE, Sindi SS, Gravano DM, Hoyer KK.

J Immunol. 2018 Jul 1;201(1):31-40. doi: 10.4049/jimmunol.1701079. Epub 2018 May 9.


Maxillofacial injuries in patients with major trauma.

McGoldrick DM, Fragoso-Iñiguez M, Lawrence T, McMillan K.

Br J Oral Maxillofac Surg. 2018 Jul;56(6):496-500. doi: 10.1016/j.bjoms.2018.04.001. Epub 2018 May 4.


Quantification of liver function by linearization of a two-compartment model of gadoxetic acid uptake using dynamic contrast-enhanced magnetic resonance imaging.

Simeth J, Johansson A, Owen D, Cuneo K, Mierzwa M, Feng M, Lawrence TS, Cao Y.

NMR Biomed. 2018 Jun;31(6):e3913. doi: 10.1002/nbm.3913. Epub 2018 Apr 19.


A pharmacokinetics and pharmacodynamics equivalence trial of the proposed pegfilgrastim biosimilar, MYL-1401H, versus reference pegfilgrastim.

Waller CF, Tiessen RG, Lawrence TE, Shaw A, Liu MS, Sharma R, Baczkowski M, Kothekar MA, Micales CE, Barve A, Ranganna GM, Pennella EJ.

J Cancer Res Clin Oncol. 2018 Jun;144(6):1087-1095. doi: 10.1007/s00432-018-2643-3. Epub 2018 Apr 18.


Live growth performance, carcass grading characteristics, and harvest yields of beef steers supplemented zilpaterol hydrochloride and offered ad libitum or maintenance energy intake.

Judy Walter LA, Schmitz AN, Nichols WT, Hutcheson JP, Lawrence TE.

J Anim Sci. 2018 May 4;96(5):1688-1703. doi: 10.1093/jas/sky105.


Host expression of PD-L1 determines efficacy of PD-L1 pathway blockade-mediated tumor regression.

Lin H, Wei S, Hurt EM, Green MD, Zhao L, Vatan L, Szeliga W, Herbst R, Harms PW, Fecher LA, Vats P, Chinnaiyan AM, Lao CD, Lawrence TS, Wicha M, Hamanishi J, Mandai M, Kryczek I, Zou W.

J Clin Invest. 2018 Apr 2;128(4):1708. doi: 10.1172/JCI120803. Epub 2018 Apr 2. No abstract available.


Estimation of carcass composition using rib dissection of calf-fed Holstein steers supplemented zilpaterol hydrochloride.

McEvers TJ, May ND, Reed JA, Walter LJ, Hutcheson JP, Lawrence TE.

J Anim Sci. 2018 Apr 14;96(4):1396-1404. doi: 10.1093/jas/sky048.


Autophagy in dendritic cells.

Ghislat G, Lawrence T.

Cell Mol Immunol. 2018 Nov;15(11):944-952. doi: 10.1038/cmi.2018.2. Epub 2018 Mar 26.


Comparison of Stereotactic Body Radiation Therapy and Radiofrequency Ablation in the Treatment of Intrahepatic Metastases.

Jackson WC, Tao Y, Mendiratta-Lala M, Bazzi L, Wahl DR, Schipper MJ, Feng M, Cuneo KC, Lawrence TS, Owen D.

Int J Radiat Oncol Biol Phys. 2018 Mar 15;100(4):950-958. doi: 10.1016/j.ijrobp.2017.12.014. Epub 2017 Dec 15.


Standard dose and dose-escalated radiation therapy are associated with favorable survival in select elderly patients with newly diagnosed glioblastoma.

Jackson WC, Tsien CI, Junck L, Leung D, Hervey-Jumper S, Orringer D, Heth J, Wahl DR, Spratt DE, Cao Y, Lawrence TS, Kim MM.

J Neurooncol. 2018 May;138(1):155-162. doi: 10.1007/s11060-018-2782-z. Epub 2018 Feb 1.


Zinc injection as a novel castration method in beef bulls: effects on performance, behavior, and testosterone and haptoglobin concentration.

Ball JJ, Kegley EB, Lawrence TE, Roberts SL, Powell JG, Richeson JT.

J Anim Sci. 2018 Apr 3;96(3):890-901. doi: 10.1093/jas/skx039.


Modeling of Normal Tissue Complications Using Imaging and Biomarkers After Radiation Therapy for Hepatocellular Carcinoma.

El Naqa I, Johansson A, Owen D, Cuneo K, Cao Y, Matuszak M, Bazzi L, Lawrence TS, Ten Haken RK.

Int J Radiat Oncol Biol Phys. 2018 Feb 1;100(2):335-343. doi: 10.1016/j.ijrobp.2017.10.005.


Host expression of PD-L1 determines efficacy of PD-L1 pathway blockade-mediated tumor regression.

Lin H, Wei S, Hurt EM, Green MD, Zhao L, Vatan L, Szeliga W, Herbst R, Harms PW, Fecher LA, Vats P, Chinnaiyan AM, Lao CD, Lawrence TS, Wicha M, Hamanishi J, Mandai M, Kryczek I, Zou W.

J Clin Invest. 2018 Feb 1;128(2):805-815. doi: 10.1172/JCI96113. Epub 2018 Jan 16.


Distal Biceps and Triceps Injuries.

Beazley JC, Lawrence TM, Drew SJ, Modi CS.

Open Orthop J. 2017 Nov 30;11:1364-1372. doi: 10.2174/1874325001711011364. eCollection 2017. Review.


GADD45β Loss Ablates Innate Immunosuppression in Cancer.

Verzella D, Bennett J, Fischietti M, Thotakura AK, Recordati C, Pasqualini F, Capece D, Vecchiotti D, D'Andrea D, Di Francesco B, De Maglie M, Begalli F, Tornatore L, Papa S, Lawrence T, Forbes SJ, Sica A, Alesse E, Zazzeroni F, Franzoso G.

Cancer Res. 2018 Mar 1;78(5):1275-1292. doi: 10.1158/0008-5472.CAN-17-1833. Epub 2017 Dec 26.


Prognostic Value of c-MET Expression in Patients With Pancreatic Cancer Receiving Adjuvant and Neoadjuvant Chemoradiation Therapy.

Cuneo KC, Morgan MA, Griffith KA, Hawkins PG, Greenson JK, Ben-Josef E, Lawrence TS, Zalupski MM.

Int J Radiat Oncol Biol Phys. 2018 Feb 1;100(2):490-497. doi: 10.1016/j.ijrobp.2017.10.030. Epub 2017 Oct 28.


Prediction of Radiation Esophagitis in Non-Small Cell Lung Cancer Using Clinical Factors, Dosimetric Parameters, and Pretreatment Cytokine Levels.

Hawkins PG, Boonstra PS, Hobson ST, Hayman JA, Ten Haken RK, Matuszak MM, Stanton P, Kalemkerian GP, Lawrence TS, Schipper MJ, Kong FS, Jolly S.

Transl Oncol. 2018 Feb;11(1):102-108. doi: 10.1016/j.tranon.2017.11.005. Epub 2017 Dec 18.


Ensuring sample quality for blood biomarker studies in clinical trials: a multicenter international study for plasma and serum sample preparation.

Kong FS, Zhao L, Wang L, Chen Y, Hu J, Fu X, Bai C, Wang L, Lawrence TS, Anscher MS, Dicker A, Okunieff P.

Transl Lung Cancer Res. 2017 Dec;6(6):625-634. doi: 10.21037/tlcr.2017.09.13.


Receptor Activator of NF-κB Orchestrates Activation of Antiviral Memory CD8 T Cells in the Spleen Marginal Zone.

Habbeddine M, Verthuy C, Rastoin O, Chasson L, Bebien M, Bajenoff M, Adriouch S, den Haan JMM, Penninger JM, Lawrence T.

Cell Rep. 2017 Nov 28;21(9):2515-2527. doi: 10.1016/j.celrep.2017.10.111.


Tumor image signatures and habitats: a processing pipeline of multimodality metabolic and physiological images.

You D, Kim MM, Aryal MP, Parmar H, Piert M, Lawrence TS, Cao Y.

J Med Imaging (Bellingham). 2018 Jan;5(1):011009. doi: 10.1117/1.JMI.5.1.011009. Epub 2017 Nov 15.


PARP1 Trapping and DNA Replication Stress Enhance Radiosensitization with Combined WEE1 and PARP Inhibitors.

Parsels LA, Karnak D, Parsels JD, Zhang Q, Vélez-Padilla J, Reichert ZR, Wahl DR, Maybaum J, O'Connor MJ, Lawrence TS, Morgan MA.

Mol Cancer Res. 2018 Feb;16(2):222-232. doi: 10.1158/1541-7786.MCR-17-0455. Epub 2017 Nov 13.


Using Indocyanine Green Extraction to Predict Liver Function After Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma.

Suresh K, Owen D, Bazzi L, Jackson W, Ten Haken RK, Cuneo K, Feng M, Lawrence TS, Schipper MJ.

Int J Radiat Oncol Biol Phys. 2018 Jan 1;100(1):131-137. doi: 10.1016/j.ijrobp.2017.09.032. Epub 2017 Sep 22.


Case Report of Multiembolic Cerebrovascular Event Associated with Ramp Study Echocardiogram.

Butera BC, Grazette LP, Lawrence T, Bowdish ME, Yoon AJ.

Case Rep Cardiol. 2017;2017:9072523. doi: 10.1155/2017/9072523. Epub 2017 Sep 28.


Neuroimaging in the Diagnosis of Chronic Traumatic Encephalopathy: A Systematic Review.

Sparks P, Lawrence T, Hinze S.

Clin J Sport Med. 2017 Oct 25. doi: 10.1097/JSM.0000000000000541. [Epub ahead of print]


Stereotactic Body Radiation Therapy as an Alternative to Transarterial Chemoembolization for Hepatocellular Carcinoma.

Sapir E, Tao Y, Schipper MJ, Bazzi L, Novelli PM, Devlin P, Owen D, Cuneo KC, Lawrence TS, Parikh ND, Feng M.

Int J Radiat Oncol Biol Phys. 2018 Jan 1;100(1):122-130. doi: 10.1016/j.ijrobp.2017.09.001. Epub 2017 Sep 14.


Serum MicroRNA Signature Predicts Response to High-Dose Radiation Therapy in Locally Advanced Non-Small Cell Lung Cancer.

Sun Y, Hawkins PG, Bi N, Dess RT, Tewari M, Hearn JWD, Hayman JA, Kalemkerian GP, Lawrence TS, Ten Haken RK, Matuszak MM, Kong FM, Jolly S, Schipper MJ.

Int J Radiat Oncol Biol Phys. 2018 Jan 1;100(1):107-114. doi: 10.1016/j.ijrobp.2017.08.039. Epub 2017 Sep 4.


Tumor-associated macrophages (TAMs) depend on ZEB1 for their cancer-promoting roles.

Cortés M, Sanchez-Moral L, de Barrios O, Fernández-Aceñero MJ, Martínez-Campanario MC, Esteve-Codina A, Darling DS, Győrffy B, Lawrence T, Dean DC, Postigo A.

EMBO J. 2017 Nov 15;36(22):3336-3355. doi: 10.15252/embj.201797345. Epub 2017 Oct 16.

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