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Seeking to improve feed efficiency in pigs through microbial modulation via fecal microbiota transplantation in sows and dietary supplementation of offspring with inulin.

McCormack UM, Curião T, Metzler-Zebeli BU, Wilkinson T, Reyer H, Crispie F, Cotter PD, Creevey CJ, Gardiner GE, Lawlor PG.

Appl Environ Microbiol. 2019 Sep 13. pii: AEM.01255-19. doi: 10.1128/AEM.01255-19. [Epub ahead of print]


Delirium: non-pharmacological and pharmacological management.

Boland JW, Lawlor PG, Bush SH.

BMJ Support Palliat Care. 2019 Jul 30. pii: bmjspcare-2019-001966. doi: 10.1136/bmjspcare-2019-001966. [Epub ahead of print] No abstract available.


Fecal Microbiota Transplant From Highly Feed Efficient Donors Affects Cecal Physiology and Microbiota in Low- and High-Feed Efficient Chickens.

Metzler-Zebeli BU, Siegerstetter SC, Magowan E, Lawlor PG, O Connell NE, Zebeli Q.

Front Microbiol. 2019 Jul 9;10:1576. doi: 10.3389/fmicb.2019.01576. eCollection 2019.


Rating Delirium Severity Using the Nursing Delirium Screening Scale: A Validation Study in Patients in Palliative Care.

Barnes CJ, Webber C, Bush SH, McNamara-Kilian M, Brodeur J, Marchington K, Sabri E, Lawlor PG.

J Pain Symptom Manage. 2019 Oct;58(4):e4-e7. doi: 10.1016/j.jpainsymman.2019.06.027. Epub 2019 Jul 5. No abstract available.


Cancer-Related Pain: A Longitudinal Study of Time to Stable Pain Control and Its Clinicodemographic Predictors.

Reis-Pina P, Sabri E, Birkett NJ, Barbosa A, Lawlor PG.

J Pain Symptom Manage. 2019 Jun 26. pii: S0885-3924(19)30350-1. doi: 10.1016/j.jpainsymman.2019.06.017. [Epub ahead of print]


Inclusion, characteristics and outcomes of people requiring palliative care in studies of non-pharmacological interventions for delirium: A systematic review.

Hosie A, Siddiqi N, Featherstone I, Johnson M, Lawlor PG, Bush SH, Amgarth-Duff I, Edwards L, Cheah SL, Phillips J, Agar M.

Palliat Med. 2019 Sep;33(8):878-899. doi: 10.1177/0269216319853487. Epub 2019 Jun 28.


Microevolution of antimicrobial resistance and biofilm formation of Salmonella Typhimurium during persistence on pig farms.

Tassinari E, Duffy G, Bawn M, Burgess CM, McCabe EM, Lawlor PG, Gardiner G, Kingsley RA.

Sci Rep. 2019 Jun 20;9(1):8832. doi: 10.1038/s41598-019-45216-w.


Porcine Feed Efficiency-Associated Intestinal Microbiota and Physiological Traits: Finding Consistent Cross-Locational Biomarkers for Residual Feed Intake.

McCormack UM, Curião T, Metzler-Zebeli BU, Magowan E, Berry DP, Reyer H, Prieto ML, Buzoianu SG, Harrison M, Rebeiz N, Crispie F, Cotter PD, O'Sullivan O, Gardiner GE, Lawlor PG.

mSystems. 2019 Jun 18;4(4). pii: e00324-18. doi: 10.1128/mSystems.00324-18.


The incidence and prevalence of delirium across palliative care settings: A systematic review.

Watt CL, Momoli F, Ansari MT, Sikora L, Bush SH, Hosie A, Kabir M, Rosenberg E, Kanji S, Lawlor PG.

Palliat Med. 2019 Sep;33(8):865-877. doi: 10.1177/0269216319854944. Epub 2019 Jun 11.


A Single Dose of Fat-Based Energy Supplement to Light Birth Weight Pigs Shortly After Birth Does Not Increase Their Survival and Growth.

Schmitt O, Baxter EM, Lawlor PG, Boyle LA, O'Driscoll K.

Animals (Basel). 2019 May 9;9(5). pii: E227. doi: 10.3390/ani9050227.


Influence of the Intestinal Microbiota on Colonization Resistance to Salmonella and the Shedding Pattern of Naturally Exposed Pigs.

Argüello H, Estellé J, Leonard FC, Crispie F, Cotter PD, O'Sullivan O, Lynch H, Walia K, Duffy G, Lawlor PG, Gardiner GE.

mSystems. 2019 Apr 23;4(2). pii: e00021-19. doi: 10.1128/mSystems.00021-19. eCollection 2019 Mar-Apr.


RNA-Seq of Liver From Pigs Divergent in Feed Efficiency Highlights Shifts in Macronutrient Metabolism, Hepatic Growth and Immune Response.

Horodyska J, Hamill RM, Reyer H, Trakooljul N, Lawlor PG, McCormack UM, Wimmers K.

Front Genet. 2019 Feb 19;10:117. doi: 10.3389/fgene.2019.00117. eCollection 2019.


Feed Restriction Reveals Distinct Serum Metabolome Profiles in Chickens Divergent in Feed Efficiency Traits.

Metzler-Zebeli BU, Siegerstetter SC, Magowan E, Lawlor PG, O'Connell NE, Zebeli Q.

Metabolites. 2019 Feb 25;9(2). pii: E38. doi: 10.3390/metabo9020038.


Feed Restriction Modifies Intestinal Microbiota-Host Mucosal Networking in Chickens Divergent in Residual Feed Intake.

Metzler-Zebeli BU, Siegerstetter SC, Magowan E, Lawlor PG, Petri RM, O Connell NE, Zebeli Q.

mSystems. 2019 Jan 29;4(1). pii: e00261-18. doi: 10.1128/mSystems.00261-18. eCollection 2019 Jan-Feb.


Multicomponent non-pharmacological intervention to prevent delirium for hospitalised people with advanced cancer: study protocol for a phase II cluster randomised controlled trial.

Hosie A, Phillips J, Lam L, Kochovska S, Noble B, Brassil M, Kurrle SE, Cumming A, Caplan GA, Chye R, Le B, Ely EW, Lawlor PG, Bush SH, Davis JM, Lovell M, Brown L, Fazekas B, Cheah SL, Edwards L, Agar M.

BMJ Open. 2019 Jan 28;9(1):e026177. doi: 10.1136/bmjopen-2018-026177.


Exploring the roles of and interactions among microbes in dry co-digestion of food waste and pig manure using high-throughput 16S rRNA gene amplicon sequencing.

Jiang Y, Dennehy C, Lawlor PG, Hu Z, McCabe M, Cormican P, Zhan X, Gardiner GE.

Biotechnol Biofuels. 2019 Jan 4;12:5. doi: 10.1186/s13068-018-1344-0. eCollection 2019.


A Scoping Review to Map Empirical Evidence Regarding Key Domains and Questions in the Clinical Pathway of Delirium in Palliative Care.

Lawlor PG, Rutkowski NA, MacDonald AR, Ansari MT, Sikora L, Momoli F, Kanji S, Wright DK, Rosenberg E, Hosie A, Pereira JL, Meagher D, Rice J, Scott J, Bush SH.

J Pain Symptom Manage. 2019 Mar;57(3):661-681.e12. doi: 10.1016/j.jpainsymman.2018.12.002. Epub 2018 Dec 12.


Feed Restriction Modulates the Fecal Microbiota Composition, Nutrient Retention, and Feed Efficiency in Chickens Divergent in Residual Feed Intake.

Siegerstetter SC, Petri RM, Magowan E, Lawlor PG, Zebeli Q, O'Connell NE, Metzler-Zebeli BU.

Front Microbiol. 2018 Nov 19;9:2698. doi: 10.3389/fmicb.2018.02698. eCollection 2018.


Inactivation of Salmonella during dry co-digestion of food waste and pig manure.

Jiang Y, Dennehy C, Lawlor PG, Hu Z, Yang Q, McCarthy G, Tan SP, Zhan X, Gardiner GE.

Waste Manag. 2018 Dec;82:231-240. doi: 10.1016/j.wasman.2018.10.037. Epub 2018 Oct 28.


Transcriptome analysis of adipose tissue from pigs divergent in feed efficiency reveals alteration in gene networks related to adipose growth, lipid metabolism, extracellular matrix, and immune response.

Horodyska J, Reyer H, Wimmers K, Trakooljul N, Lawlor PG, Hamill RM.

Mol Genet Genomics. 2019 Apr;294(2):395-408. doi: 10.1007/s00438-018-1515-5. Epub 2018 Nov 27.


RNA-seq of muscle from pigs divergent in feed efficiency and product quality identifies differences in immune response, growth, and macronutrient and connective tissue metabolism.

Horodyska J, Wimmers K, Reyer H, Trakooljul N, Mullen AM, Lawlor PG, Hamill RM.

BMC Genomics. 2018 Nov 1;19(1):791. doi: 10.1186/s12864-018-5175-y.


Inhibition of volatile fatty acids on methane production kinetics during dry co-digestion of food waste and pig manure.

Jiang Y, Dennehy C, Lawlor PG, Hu Z, McCabe M, Cormican P, Zhan X, Gardiner GE.

Waste Manag. 2018 Sep;79:302-311. doi: 10.1016/j.wasman.2018.07.049. Epub 2018 Aug 4.


Moderate to Severe Cancer Pain: Are We Taking Serious Action? The Opioid Prescribing Scenario in Portugal.

Reis-Pina P, Lawlor PG, Barbosa A.

Acta Med Port. 2018 Sep 28;31(9):451-453. doi: 10.20344/amp.10999. Epub 2018 Sep 28. No abstract available.


An association analysis of sow parity, live-weight and back-fat depth as indicators of sow productivity.

Lavery A, Lawlor PG, Magowan E, Miller HM, O'Driscoll K, Berry DP.

Animal. 2019 Mar;13(3):622-630. doi: 10.1017/S1751731118001799. Epub 2018 Jul 18.


Delirium in adult cancer patients: ESMO Clinical Practice Guidelines.

Bush SH, Lawlor PG, Ryan K, Centeno C, Lucchesi M, Kanji S, Siddiqi N, Morandi A, Davis DHJ, Laurent M, Schofield N, Barallat E, Ripamonti CI; ESMO Guidelines Committee.

Ann Oncol. 2018 Oct 1;29(Suppl 4):iv143-iv165. doi: 10.1093/annonc/mdy147. No abstract available.


Interactions between metabolically active bacteria and host gene expression at the cecal mucosa in pigs of diverging feed efficiency.

Metzler-Zebeli BU, Lawlor PG, Magowan E, Zebeli Q.

J Anim Sci. 2018 Jun 4;96(6):2249-2264. doi: 10.1093/jas/sky118.


Authors' Reply.

Reis-Pina P, Acharya A, Lawlor PG.

J Pain Symptom Manage. 2018 Jul;56(1):e9-e10. doi: 10.1016/j.jpainsymman.2018.03.027. Epub 2018 Apr 11. No abstract available.


Fecal Microbiota Transplantation in Gestating Sows and Neonatal Offspring Alters Lifetime Intestinal Microbiota and Growth in Offspring.

McCormack UM, Curião T, Wilkinson T, Metzler-Zebeli BU, Reyer H, Ryan T, Calderon-Diaz JA, Crispie F, Cotter PD, Creevey CJ, Gardiner GE, Lawlor PG.

mSystems. 2018 Mar 13;3(3). pii: e00134-17. doi: 10.1128/mSystems.00134-17. eCollection 2018 May-Jun.


Surveillance Data Highlights Feed Form, Biosecurity, and Disease Control as Significant Factors Associated with Salmonella Infection on Farrow-to-Finish Pig Farms.

Argüello H, Manzanilla EG, Lynch H, Walia K, Leonard FC, Egan J, Duffy G, Gardiner GE, Lawlor PG.

Front Microbiol. 2018 Feb 15;9:187. doi: 10.3389/fmicb.2018.00187. eCollection 2018.


Reducing BW loss during lactation in sows: a meta-analysis on the use of a nonstarch polysaccharide-hydrolyzing enzyme supplement.

Cozannet P, Lawlor PG, Leterme P, Devillard E, Geraert PA, Rouffineau F, Preynat A.

J Anim Sci. 2018 Jun 29;96(7):2777-2788. doi: 10.1093/jas/sky045.


Differences in intestinal size, structure, and function contributing to feed efficiency in broiler chickens reared at geographically distant locations.

Metzler-Zebeli BU, Magowan E, Hollmann M, Ball MEE, Molnár A, Witter K, Ertl R, Hawken RJ, Lawlor PG, O'Connell NE, Aschenbach J, Zebeli Q.

Poult Sci. 2018 Feb 1;97(2):578-591. doi: 10.3382/ps/pex332.


Analysis of meat quality traits and gene expression profiling of pigs divergent in residual feed intake.

Horodyska J, Oster M, Reyer H, Mullen AM, Lawlor PG, Wimmers K, Hamill RM.

Meat Sci. 2018 Mar;137:265-274. doi: 10.1016/j.meatsci.2017.11.021. Epub 2017 Nov 20.


Salmonella in breeding pigs: Shedding pattern, transmission of infection and the role of environmental contamination in Irish commercial farrow-to-finish herds.

Lynch H, Walia K, Leonard FC, Lawlor PG, Manzanilla EG, Grant J, Duffy G, Gardiner GE, Cormican M, King J, Markey BK, Fanning S, Argüello H.

Zoonoses Public Health. 2018 Feb;65(1):e196-e206. doi: 10.1111/zph.12428. Epub 2017 Nov 27.


Intestinal microbiota profiles associated with low and high residual feed intake in chickens across two geographical locations.

Siegerstetter SC, Schmitz-Esser S, Magowan E, Wetzels SU, Zebeli Q, Lawlor PG, O'Connell NE, Metzler-Zebeli BU.

PLoS One. 2017 Nov 15;12(11):e0187766. doi: 10.1371/journal.pone.0187766. eCollection 2017.


Anaerobic co-digestion of pig manure and food waste; effects on digestate biosafety, dewaterability, and microbial community dynamics.

Dennehy C, Lawlor PG, McCabe MS, Cormican P, Sheahan J, Jiang Y, Zhan X, Gardiner GE.

Waste Manag. 2018 Jan;71:532-541. doi: 10.1016/j.wasman.2017.10.047. Epub 2017 Nov 4.


Fecal Microbiota Transplant from Highly Feed-Efficient Donors Shows Little Effect on Age-Related Changes in Feed-Efficiency-Associated Fecal Microbiota from Chickens.

Siegerstetter SC, Petri RM, Magowan E, Lawlor PG, Zebeli Q, O'Connell NE, Metzler-Zebeli BU.

Appl Environ Microbiol. 2018 Jan 2;84(2). pii: e02330-17. doi: 10.1128/AEM.02330-17. Print 2018 Jan 15.


Adequacy of cancer-related pain management and predictors of undertreatment at referral to a pain clinic.

Reis-Pina P, Lawlor PG, Barbosa A.

J Pain Res. 2017 Aug 31;10:2097-2107. doi: 10.2147/JPR.S139715. eCollection 2017.


Cancer Pain With a Neuropathic Component: A Cross-sectional Study of Its Clinical Characteristics, Associated Psychological Distress, Treatments, and Predictors at Referral to a Cancer Pain Clinic.

Reis-Pina P, Acharya A, Lawlor PG.

J Pain Symptom Manage. 2018 Feb;55(2):297-306. doi: 10.1016/j.jpainsymman.2017.08.028. Epub 2017 Sep 21.


Clinical Assessment and Management of Delirium in the Palliative Care Setting.

Bush SH, Tierney S, Lawlor PG.

Drugs. 2017 Oct;77(15):1623-1643. doi: 10.1007/s40265-017-0804-3. Review.


Inactivation of enteric indicator bacteria and system stability during dry co-digestion of food waste and pig manure.

Jiang Y, Dennehy C, Lawlor PG, Hu Z, Zhan X, Gardiner GE.

Sci Total Environ. 2018 Jan 15;612:293-302. doi: 10.1016/j.scitotenv.2017.08.214. Epub 2017 Sep 1.


Assessing serum metabolite profiles as predictors for feed efficiency in broiler chickens reared at geographically distant locations.

Metzler-Zebeli BU, Magowan E, Hollmann M, Ball MEE, Molnár A, Lawlor PG, Hawken RJ, O'Connell NE, Zebeli Q.

Br Poult Sci. 2017 Dec;58(6):729-738. doi: 10.1080/00071668.2017.1362688. Epub 2017 Aug 31.


Feed efficiency metrics in growing pigs.

Calderón Díaz JA, Berry DP, Rebeiz N, Metzler-Zebeli BU, Magowan E, Gardiner GE, Lawlor PG.

J Anim Sci. 2017 Jul;95(7):3037-3046. doi: 10.2527/jas.2017.1554.


Exploring a Possible Link between the Intestinal Microbiota and Feed Efficiency in Pigs.

McCormack UM, Curião T, Buzoianu SG, Prieto ML, Ryan T, Varley P, Crispie F, Magowan E, Metzler-Zebeli BU, Berry D, O'Sullivan O, Cotter PD, Gardiner GE, Lawlor PG.

Appl Environ Microbiol. 2017 Jul 17;83(15). pii: e00380-17. doi: 10.1128/AEM.00380-17. Print 2017 Aug 1.


Finishing pigs that are divergent in feed efficiency show small differences in intestinal functionality and structure.

Metzler-Zebeli BU, Lawlor PG, Magowan E, McCormack UM, Curião T, Hollmann M, Ertl R, Aschenbach JR, Zebeli Q.

PLoS One. 2017 Apr 5;12(4):e0174917. doi: 10.1371/journal.pone.0174917. eCollection 2017.


Investigation of in-feed organic acids as a low cost strategy to combat Salmonella in grower pigs.

Lynch H, Leonard FC, Walia K, Lawlor PG, Duffy G, Fanning S, Markey BK, Brady C, Gardiner GE, Argüello H.

Prev Vet Med. 2017 Apr 1;139(Pt A):50-57. doi: 10.1016/j.prevetmed.2017.02.008. Epub 2017 Feb 20.


The efficacy of different cleaning and disinfection procedures to reduce Salmonella and Enterobacteriaceae in the lairage environment of a pig abattoir.

Walia K, Argüello H, Lynch H, Grant J, Leonard FC, Lawlor PG, Gardiner GE, Duffy G.

Int J Food Microbiol. 2017 Apr 4;246:64-71. doi: 10.1016/j.ijfoodmicro.2017.02.002. Epub 2017 Feb 6.


Effect of strategic administration of an encapsulated blend of formic acid, citric acid, and essential oils on Salmonella carriage, seroprevalence, and growth of finishing pigs.

Walia K, Argüello H, Lynch H, Leonard FC, Grant J, Yearsley D, Kelly S, Duffy G, Gardiner GE, Lawlor PG.

Prev Vet Med. 2017 Feb 1;137(Pt A):28-35. doi: 10.1016/j.prevetmed.2016.12.007. Epub 2016 Dec 12.


Efficacy of Oral Risperidone, Haloperidol, or Placebo for Symptoms of Delirium Among Patients in Palliative Care: A Randomized Clinical Trial.

Agar MR, Lawlor PG, Quinn S, Draper B, Caplan GA, Rowett D, Sanderson C, Hardy J, Le B, Eckermann S, McCaffrey N, Devilee L, Fazekas B, Hill M, Currow DC.

JAMA Intern Med. 2017 Jan 1;177(1):34-42. doi: 10.1001/jamainternmed.2016.7491. Erratum in: JAMA Intern Med. 2017 Feb 1;177(2):293.


Symptom clusters and survival in Portuguese patients with advanced cancer.

Barata PC, Cardoso A, Custodio MP, Alves M, Papoila AL, António B, Lawlor PG.

Cancer Med. 2016 Oct;5(10):2731-2739. doi: 10.1002/cam4.860. Epub 2016 Sep 13.

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