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Synthesis of Water-Soluble Chiral DOTA Lanthanide Complexes with Predominantly Twisted Square Antiprism Isomers and Circularly Polarized Luminescence.

Dai L, Zhang J, Chen Y, Mackenzie LE, Pal R, Law GL.

Inorg Chem. 2019 Oct 7;58(19):12506-12510. doi: 10.1021/acs.inorgchem.9b01799. Epub 2019 Sep 6.


Catalytic asymmetric oxo-Diels-Alder reactions with chiral atropisomeric biphenyl diols.

Yeung CT, Chan WTK, Lo WS, Law GL, Wong WT.

Beilstein J Org Chem. 2019 Apr 18;15:955-962. doi: 10.3762/bjoc.15.92. eCollection 2019.


Breaking the 1,2-HOPO barrier with a cyclen backbone for more efficient sensitization of Eu(iii) luminescence and unprecedented two-photon excitation properties.

Dai L, Lo WS, Gu Y, Xiong Q, Wong KL, Kwok WM, Wong WT, Law GL.

Chem Sci. 2019 Mar 28;10(17):4550-4559. doi: 10.1039/c9sc00244h. eCollection 2019 May 7.


Triboluminescence of Centrosymmetric Lanthanide β-Diketonate Complexes with Aggregation-Induced Emission.

Wong HY, Chan WTK, Law GL.

Molecules. 2019 Feb 13;24(4). pii: E662. doi: 10.3390/molecules24040662.


Synthesis of a Conformationally Stable Atropisomeric Pair of Biphenyl Scaffold Containing Additional Stereogenic Centers.

Yeung CT, Chan WTK, Lo WS, Law GL, Wong WT.

Molecules. 2019 Feb 12;24(3). pii: E643. doi: 10.3390/molecules24030643.


EBNA1-targeted inhibitors: Novel approaches for the treatment of Epstein-Barr virus-associated cancers.

Jiang L, Xie C, Lung HL, Lo KW, Law GL, Mak NK, Wong KL.

Theranostics. 2018 Oct 22;8(19):5307-5319. doi: 10.7150/thno.26823. eCollection 2018. Review.


Assembly of Lanthanide(III) Cubanes and Dimers with Single-Molecule Magnetism and Photoluminescence.

Wong HY, Chan WTK, Law GL.

Inorg Chem. 2018 Jun 18;57(12):6893-6902. doi: 10.1021/acs.inorgchem.8b00505. Epub 2018 May 29.


Chiral DOTA chelators as an improved platform for biomedical imaging and therapy applications.

Dai L, Jones CM, Chan WTK, Pham TA, Ling X, Gale EM, Rotile NJ, Tai WC, Anderson CJ, Caravan P, Law GL.

Nat Commun. 2018 Feb 27;9(1):857. doi: 10.1038/s41467-018-03315-8.


Corrigendum: Interband Absorption Enhanced Optical Activity in Discrete Au@Ag Core-Shell Nanocuboids: Probing Extended Helical Conformation of Chemisorbed Cysteine Molecules.

Bao ZY, Zhang W, Zhang YL, He J, Dai J, Yeung CT, Law GL, Lei DY.

Angew Chem Int Ed Engl. 2018 Jan 22;57(4):870. doi: 10.1002/anie.201712503. No abstract available.


Gadolinium and Platinum in Tandem: Real-time Multi-Modal Monitoring of Drug Delivery by MRI and Fluorescence Imaging.

Li H, Harriss BI, Phinikaridou A, Lacerda S, Ramniceanu G, Doan BT, Ho KL, Chan CF, Lo WS, Botnar RM, Lan R, Richard C, Law GL, Long NJ, Wong KL.

Nanotheranostics. 2017 May 8;1(2):186-195. doi: 10.7150/ntno.18619. eCollection 2017.


Chiral transcription in self-assembled tetrahedral Eu4L6 chiral cages displaying sizable circularly polarized luminescence.

Yeung CT, Yim KH, Wong HY, Pal R, Lo WS, Yan SC, Yee-Man Wong M, Yufit D, Smiles DE, McCormick LJ, Teat SJ, Shuh DK, Wong WT, Law GL.

Nat Commun. 2017 Oct 24;8(1):1128. doi: 10.1038/s41467-017-01025-1.


A Smart Europium-Ruthenium Complex as Anticancer Prodrug: Controllable Drug Release and Real-Time Monitoring under Different Light Excitations.

Li H, Xie C, Lan R, Zha S, Chan CF, Wong WY, Ho KL, Chan BD, Luo Y, Zhang JX, Law GL, Tai WCS, Bünzli JG, Wong KL.

J Med Chem. 2017 Nov 9;60(21):8923-8932. doi: 10.1021/acs.jmedchem.7b01162. Epub 2017 Oct 19.


Mechanistic Investigation of Inducing Triboluminescence in Lanthanide(III) β-Diketonate Complexes.

Wong HY, Lo WS, Chan WTK, Law GL.

Inorg Chem. 2017 May 1;56(9):5135-5140. doi: 10.1021/acs.inorgchem.7b00273. Epub 2017 Apr 7.


Interband Absorption Enhanced Optical Activity in Discrete Au@Ag Core-Shell Nanocuboids: Probing Extended Helical Conformation of Chemisorbed Cysteine Molecules.

Bao ZY, Zhang W, Zhang YL, He J, Dai J, Yeung CT, Law GL, Lei DY.

Angew Chem Int Ed Engl. 2017 Jan 24;56(5):1283-1288. doi: 10.1002/anie.201607563. Epub 2016 Dec 22. Erratum in: Angew Chem Int Ed Engl. 2018 Jan 22;57(4):870.


αvβ3-Isoform specific erbium complexes highly specific for bladder cancer imaging and photodynamic therapy.

Zhou Y, Chan CF, Kwong DW, Law GL, Cobb S, Wong WK, Wong KL.

Chem Commun (Camb). 2017 Jan 3;53(3):557-560. doi: 10.1039/c6cc09246b.


New Class of Bright and Highly Stable Chiral Cyclen Europium Complexes for Circularly Polarized Luminescence Applications.

Dai L, Lo WS, Coates ID, Pal R, Law GL.

Inorg Chem. 2016 Sep 6;55(17):9065-70. doi: 10.1021/acs.inorgchem.6b01546. Epub 2016 Aug 18.


Thermodynamic selectivity of functional agents on zeolite for sodium dodecyl sulfate sequestration.

Leng L, Wang J, Qiu X, Zhao Y, Yip YW, Law GL, Shih K, Zhou Z, Lee PH.

J Hazard Mater. 2016 Nov 15;318:41-47. doi: 10.1016/j.jhazmat.2016.06.043. Epub 2016 Jun 22.


A smart "off-on" gate for the in situ detection of hydrogen sulphide with Cu(ii)-assisted europium emission.

Liang Z, Tsoi TH, Chan CF, Dai L, Wu Y, Du G, Zhu L, Lee CS, Wong WT, Law GL, Wong KL.

Chem Sci. 2016 Mar 1;7(3):2151-2156. doi: 10.1039/c5sc04091d. Epub 2015 Dec 7.


Effects of Ligand Geometry on the Photophysical Properties of Photoluminescent Eu(III) and Sm(III) 1-Hydroxypyridin-2-one Complexes in Aqueous Solution.

Daumann LJ, Tatum DS, Andolina CM, Pacold JI, D'Aléo A, Law GL, Xu J, Raymond KN.

Inorg Chem. 2016 Jan 4;55(1):114-24. doi: 10.1021/acs.inorgchem.5b01927. Epub 2015 Dec 17.


A highly selective on-off-on responsive lanthanide(iii) based probe for recognition of copper and hydrogen sulfide.

Yip YW, Law GL, Wong WT.

Dalton Trans. 2016 Jan 21;45(3):928-35. doi: 10.1039/c5dt03627e.


Highly luminescent Sm(III) complexes with intraligand charge-transfer sensitization and the effect of solvent polarity on their luminescent properties.

Lo WS, Zhang J, Wong WT, Law GL.

Inorg Chem. 2015 Apr 20;54(8):3725-7. doi: 10.1021/acs.inorgchem.5b00331. Epub 2015 Apr 2.


New insights into structure and luminescence of Eu(III) and Sm(III) complexes of the 3,4,3-LI(1,2-HOPO) ligand.

Daumann LJ, Tatum DS, Snyder BE, Ni C, Law GL, Solomon EI, Raymond KN.

J Am Chem Soc. 2015 Mar 4;137(8):2816-9. doi: 10.1021/ja5116524. Epub 2015 Feb 19.


Next-generation sequencing reveals a controlled immune response to Zaire Ebola virus challenge in cynomolgus macaques immunized with vesicular stomatitis virus expressing Zaire Ebola virus glycoprotein (VSVΔG/EBOVgp).

Barrenas F, Green RR, Thomas MJ, Law GL, Proll SC, Engelmann F, Messaoudi I, Marzi A, Feldmann H, Katze MG.

Clin Vaccine Immunol. 2015 Mar;22(3):354-6. doi: 10.1128/CVI.00733-14. Epub 2015 Jan 14.


Cytokine systems approach demonstrates differences in innate and pro-inflammatory host responses between genetically distinct MERS-CoV isolates.

Selinger C, Tisoncik-Go J, Menachery VD, Agnihothram S, Law GL, Chang J, Kelly SM, Sova P, Baric RS, Katze MG.

BMC Genomics. 2014 Dec 22;15:1161. doi: 10.1186/1471-2164-15-1161.


In vivo selective cancer-tracking gadolinium eradicator as new-generation photodynamic therapy agent.

Zhang T, Lan R, Chan CF, Law GL, Wong WK, Wong KL.

Proc Natl Acad Sci U S A. 2014 Dec 23;111(51):E5492-7. doi: 10.1073/pnas.1414499111. Epub 2014 Dec 1.


Lanthanide supramolecular helical diastereoselective breaking induced by point chirality: mixture or P-helix, M-helix.

Yeung CT, Chan WT, Yan SC, Yu KL, Yim KH, Wong WT, Law GL.

Chem Commun (Camb). 2015 Jan 11;51(3):592-5. doi: 10.1039/c4cc08362h. Epub 2014 Nov 21.


The draft genome sequence of the ferret (Mustela putorius furo) facilitates study of human respiratory disease.

Peng X, Alföldi J, Gori K, Eisfeld AJ, Tyler SR, Tisoncik-Go J, Brawand D, Law GL, Skunca N, Hatta M, Gasper DJ, Kelly SM, Chang J, Thomas MJ, Johnson J, Berlin AM, Lara M, Russell P, Swofford R, Turner-Maier J, Young S, Hourlier T, Aken B, Searle S, Sun X, Yi Y, Suresh M, Tumpey TM, Siepel A, Wisely SM, Dessimoz C, Kawaoka Y, Birren BW, Lindblad-Toh K, Di Palma F, Engelhardt JF, Palermo RE, Katze MG.

Nat Biotechnol. 2014 Dec;32(12):1250-5. doi: 10.1038/nbt.3079. Epub 2014 Nov 17.


Multiple low-dose challenges in a rhesus macaque AIDS vaccine trial result in an evolving host response that affects protective outcome.

Selinger C, Strbo N, Gonzalez L, Aicher L, Weiss JM, Law GL, Palermo RE, Vaccari M, Franchini G, Podack ER, Katze MG.

Clin Vaccine Immunol. 2014 Dec;21(12):1650-60. doi: 10.1128/CVI.00455-14. Epub 2014 Oct 1.


A lysosome-specific two-photon phosphorescent binuclear cyclometalated platinum(II) probe for in vivo imaging of live neurons.

Ho YM, Au NP, Wong KL, Chan CT, Kwok WM, Law GL, Tang KK, Wong WY, Ma CH, Lam MH.

Chem Commun (Camb). 2014 Apr 25;50(32):4161-3. doi: 10.1039/c3cc48934e.


A comprehensive collection of systems biology data characterizing the host response to viral infection.

Aevermann BD, Pickett BE, Kumar S, Klem EB, Agnihothram S, Askovich PS, Bankhead A 3rd, Bolles M, Carter V, Chang J, Clauss TR, Dash P, Diercks AH, Eisfeld AJ, Ellis A, Fan S, Ferris MT, Gralinski LE, Green RR, Gritsenko MA, Hatta M, Heegel RA, Jacobs JM, Jeng S, Josset L, Kaiser SM, Kelly S, Law GL, Li C, Li J, Long C, Luna ML, Matzke M, McDermott J, Menachery V, Metz TO, Mitchell H, Monroe ME, Navarro G, Neumann G, Podyminogin RL, Purvine SO, Rosenberger CM, Sanders CJ, Schepmoes AA, Shukla AK, Sims A, Sova P, Tam VC, Tchitchek N, Thomas PG, Tilton SC, Totura A, Wang J, Webb-Robertson BJ, Wen J, Weiss JM, Yang F, Yount B, Zhang Q, McWeeney S, Smith RD, Waters KM, Kawaoka Y, Baric R, Aderem A, Katze MG, Scheuermann RH.

Sci Data. 2014 Oct 14;1:140033. doi: 10.1038/sdata.2014.33. eCollection 2014.


Drug repurposing: a better approach for infectious disease drug discovery?

Law GL, Tisoncik-Go J, Korth MJ, Katze MG.

Curr Opin Immunol. 2013 Oct;25(5):588-92. doi: 10.1016/j.coi.2013.08.004. Epub 2013 Sep 5. Review.


Mechanisms of severe acute respiratory syndrome coronavirus-induced acute lung injury.

Gralinski LE, Bankhead A 3rd, Jeng S, Menachery VD, Proll S, Belisle SE, Matzke M, Webb-Robertson BJ, Luna ML, Shukla AK, Ferris MT, Bolles M, Chang J, Aicher L, Waters KM, Smith RD, Metz TO, Law GL, Katze MG, McWeeney S, Baric RS.

MBio. 2013 Aug 6;4(4). pii: e00271-13. doi: 10.1128/mBio.00271-13.


Real time detection of cell cycle regulator cyclin A on living tumor cells with europium emission.

Li H, Chadbourne FL, Lan R, Chan CF, Chan WL, Law GL, Lee CS, Cobb SL, Wong KL.

Dalton Trans. 2013 Oct 7;42(37):13495-501. doi: 10.1039/c3dt51053k. Epub 2013 Jul 30.


Systems virology: host-directed approaches to viral pathogenesis and drug targeting.

Law GL, Korth MJ, Benecke AG, Katze MG.

Nat Rev Microbiol. 2013 Jul;11(7):455-66. doi: 10.1038/nrmicro3036. Epub 2013 Jun 3. Review.


Circularly polarized luminescence of curium: a new characterization of the 5f actinide complexes.

Law GL, Andolina CM, Xu J, Luu V, Rutkowski PX, Muller G, Shuh DK, Gibson JK, Raymond KN.

J Am Chem Soc. 2012 Sep 19;134(37):15545-9. Epub 2012 Sep 11.


A potential water-soluble ytterbium-based porphyrin-cyclen dual bio-probe for Golgi apparatus imaging and photodynamic therapy.

Zhang JX, Li H, Chan CF, Lan R, Chan WL, Law GL, Wong WK, Wong KL.

Chem Commun (Camb). 2012 Oct 7;48(77):9646-8. doi: 10.1039/c2cc34963a.


A single sensitizer for the excitation of visible and NIR lanthanide emitters in water with high quantum yields.

Law GL, Pham TA, Xu J, Raymond KN.

Angew Chem Int Ed Engl. 2012 Mar 5;51(10):2371-4. doi: 10.1002/anie.201106748. Epub 2012 Jan 24. No abstract available.


Analysis of nucleosome positioning using a nucleosome-scanning assay.

Infante JJ, Law GL, Young ET.

Methods Mol Biol. 2012;833:63-87. doi: 10.1007/978-1-61779-477-3_5.


Octadentate cages of Tb(III) 2-hydroxyisophthalamides: a new standard for luminescent lanthanide labels.

Xu J, Corneillie TM, Moore EG, Law GL, Butlin NG, Raymond KN.

J Am Chem Soc. 2011 Dec 14;133(49):19900-10. doi: 10.1021/ja2079898. Epub 2011 Nov 14.


Next-generation sequencing reveals HIV-1-mediated suppression of T cell activation and RNA processing and regulation of noncoding RNA expression in a CD4+ T cell line.

Chang ST, Sova P, Peng X, Weiss J, Law GL, Palermo RE, Katze MG.

MBio. 2011 Sep 20;2(5). pii: e00134-11. doi: 10.1128/mBio.00134-11. Print 2011.


Responsive two-photon induced europium emission as fluorescent indicator for paralytic shellfish saxitoxin.

He S, Li H, Yip YW, Yeung CT, Fung YO, Kong HK, Yeung HL, Law GL, Wong KL, Lee CS, Lam MH, Murphy MB, Lam PK, Wong WT.

Org Lett. 2011 Oct 7;13(19):5036-9. doi: 10.1021/ol2018246. Epub 2011 Sep 6.


Host regulatory network response to infection with highly pathogenic H5N1 avian influenza virus.

Li C, Bankhead A 3rd, Eisfeld AJ, Hatta Y, Jeng S, Chang JH, Aicher LD, Proll S, Ellis AL, Law GL, Waters KM, Neumann G, Katze MG, McWeeney S, Kawaoka Y.

J Virol. 2011 Nov;85(21):10955-67. doi: 10.1128/JVI.05792-11. Epub 2011 Aug 24.


Two-photon induced responsive f-f emissive detection of Cyclin A with a europium-chelating peptide.

Kong HK, Chadbourne FL, Law GL, Li H, Tam HL, Cobb SL, Lau CK, Lee CS, Wong KL.

Chem Commun (Camb). 2011 Jul 28;47(28):8052-4. doi: 10.1039/c1cc12811f. Epub 2011 Jun 16.


Evidence for the optical signalling of changes in bicarbonate concentration within the mitochondrial region of living cells.

Smith DG, Law GL, Murray BS, Pal R, Parker D, Wong KL.

Chem Commun (Camb). 2011 Jul 14;47(26):7347-9. doi: 10.1039/c1cc11853f. Epub 2011 Jun 2.


In vitro imaging and human serum albumin responsive dimeric lanthanide DO3A complex.

Fung YO, Wu W, Yeung CT, Kong HK, Wong KK, Lo WS, Law GL, Wong KL, Lau CK, Lee CS, Wong WT.

Inorg Chem. 2011 Jun 20;50(12):5517-25. doi: 10.1021/ic2004672. Epub 2011 May 18.


Impressive europium red emission induced by two-photon excitation for biological applications.

Lo WS, Kwok WM, Law GL, Yeung CT, Chan CT, Yeung HL, Kong HK, Chen CH, Murphy MB, Wong KL, Wong WT.

Inorg Chem. 2011 Jun 20;50(12):5309-11. doi: 10.1021/ic102465j. Epub 2011 May 16.


Simultaneous synthesis and functionalization of water-soluble up-conversion nanoparticles for in-vitro cell and nude mouse imaging.

Wang ZL, Hao J, Chan HL, Law GL, Wong WT, Wong KL, Murphy MB, Su T, Zhang ZH, Zeng SQ.

Nanoscale. 2011 May;3(5):2175-81. doi: 10.1039/c1nr10090d. Epub 2011 Mar 24.


Activator-independent transcription of Snf1-dependent genes in mutants lacking histone tails.

Infante JJ, Law GL, Wang IT, Chang HW, Young ET.

Mol Microbiol. 2011 Apr;80(2):407-22. doi: 10.1111/j.1365-2958.2011.07583.x. Epub 2011 Mar 1.


A systems biology approach to infectious disease research: innovating the pathogen-host research paradigm.

Aderem A, Adkins JN, Ansong C, Galagan J, Kaiser S, Korth MJ, Law GL, McDermott JG, Proll SC, Rosenberger C, Schoolnik G, Katze MG.

MBio. 2011 Mar 1;2(1):e00325-10. doi: 10.1128/mBio.00325-10.


Synthesis and comparative anion binding profiles of two di-aqua Eu(III) complexes.

Imperio D, Giovenzana GB, Law GL, Parker D, Walton JW.

Dalton Trans. 2010 Nov 7;39(41):9897-903. doi: 10.1039/c0dt00773k. Epub 2010 Sep 17.


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