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A functional variant in UBE2L3 contributes to HBV infection and maintains cccDNA stability by inducing degradation of APOBEC3A protein.

Zhou L, Ren JH, Cheng ST, Xu HM, Chen WX, Chen DP, Wong VKW, Law BYK, Liu Y, Cai XF, Tang H, Yu HB, Hu JL, Hu Y, Zhou HZ, Ren F, He L, Hu ZW, Jiang H, Xu HY, Huang AL, Chen J.

Hepatology. 2019 Jan 7. doi: 10.1002/hep.30497. [Epub ahead of print]


Functional Peptide Nanofibers with Unique Tumor Targeting and Enzyme-Induced Local Retention Properties.

Bellat V, Ting R, Southard TL, Vahdat L, Molina H, Fernandez J, Aras O, Stokol T, Law B.

Adv Funct Mater. 2018 Oct 31;28(44). pii: 1803969. doi: 10.1002/adfm.201803969. Epub 2018 Sep 14.


Amide proton transfer MRI detects early changes in nasopharyngeal carcinoma: providing a potential imaging marker for treatment response.

Qamar S, King AD, Ai QY, Law BKH, Chan JSM, Poon DMC, Tong M, Mo FKF, Chen W, Bhatia KS, Ahuja AT, Ma BBY, Yeung DK, Wang YX, Yuan J.

Eur Arch Otorhinolaryngol. 2018 Dec 3. doi: 10.1007/s00405-018-5231-x. [Epub ahead of print]


Novel dauricine derivatives suppress cancer via autophagy-dependent cell death.

Zhou X, Qu YQ, Zheng Z, Law BYK, Mok SWF, Jiang ZH, Wong VKW, Bai LP.

Bioorg Chem. 2018 Nov 2;83:450-460. doi: 10.1016/j.bioorg.2018.10.074. [Epub ahead of print]


Near-future forest vulnerability to drought and fire varies across the western United States.

Buotte PC, Levis S, Law BE, Hudiburg TW, Rupp DE, Kent JJ.

Glob Chang Biol. 2019 Jan;25(1):290-303. doi: 10.1111/gcb.14490. Epub 2018 Nov 15.


Effects of metformin treatment on radiotherapy efficacy in patients with cancer and diabetes: a systematic review and meta-analysis.

Rao M, Gao C, Guo M, Law BYK, Xu Y.

Cancer Manag Res. 2018 Oct 24;10:4881-4890. doi: 10.2147/CMAR.S174535. eCollection 2018. Review.


ASR352, A potent anticancer agent: Synthesis, preliminary SAR, and biological activities against colorectal cancer bulk, 5-fluorouracil/oxaliplatin resistant and stem cells.

Narayan S, Ramisetti S, Jaiswal AS, Law BK, Singh-Pillay A, Singh P, Amin S, Sharma AK.

Eur J Med Chem. 2019 Jan 1;161:456-467. doi: 10.1016/j.ejmech.2018.10.052. Epub 2018 Oct 23.


Passive acoustics and sound recognition provide new insights on status and resilience of an iconic endangered marsupial (koala Phascolarctos cinereus) to timber harvesting.

Law BS, Brassil T, Gonsalves L, Roe P, Truskinger A, McConville A.

PLoS One. 2018 Oct 31;13(10):e0205075. doi: 10.1371/journal.pone.0205075. eCollection 2018.


The relationship between physical literacy scores and adherence to Canadian physical activity and sedentary behaviour guidelines.

Belanger K, Barnes JD, Longmuir PE, Anderson KD, Bruner B, Copeland JL, Gregg MJ, Hall N, Kolen AM, Lane KN, Law B, MacDonald DJ, Martin LJ, Saunders TJ, Sheehan D, Stone M, Woodruff SJ, Tremblay MS.

BMC Public Health. 2018 Oct 2;18(Suppl 2):1042. doi: 10.1186/s12889-018-5897-4.


The relationship between sedentary behaviour and physical literacy in Canadian children: a cross-sectional analysis from the RBC-CAPL Learn to Play study.

Saunders TJ, MacDonald DJ, Copeland JL, Longmuir PE, Barnes JD, Belanger K, Bruner B, Gregg MJ, Hall N, Kolen AM, Law B, Martin LJ, Sheehan D, Stone MR, Woodruff SJ, Tremblay MS.

BMC Public Health. 2018 Oct 2;18(Suppl 2):1037. doi: 10.1186/s12889-018-5892-9.


Cardiorespiratory fitness is associated with physical literacy in a large sample of Canadian children aged 8 to 12 years.

Lang JJ, Chaput JP, Longmuir PE, Barnes JD, Belanger K, Tomkinson GR, Anderson KD, Bruner B, Copeland JL, Gregg MJ, Hall N, Kolen AM, Lane KN, Law B, MacDonald DJ, Martin LJ, Saunders TJ, Sheehan D, Stone MR, Woodruff SJ, Tremblay MS.

BMC Public Health. 2018 Oct 2;18(Suppl 2):1041. doi: 10.1186/s12889-018-5896-5.


Physical literacy levels of Canadian children aged 8-12 years: descriptive and normative results from the RBC Learn to Play-CAPL project.

Tremblay MS, Longmuir PE, Barnes JD, Belanger K, Anderson KD, Bruner B, Copeland JL, Delisle Nyström C, Gregg MJ, Hall N, Kolen AM, Lane KN, Law B, MacDonald DJ, Martin LJ, Saunders TJ, Sheehan D, Stone MR, Woodruff SJ.

BMC Public Health. 2018 Oct 2;18(Suppl 2):1036. doi: 10.1186/s12889-018-5891-x.


Associations between teacher training and measures of physical literacy among Canadian 8- to 12-year-old students.

Law B, Bruner B, Scharoun Benson SM, Anderson K, Gregg M, Hall N, Lane K, MacDonald DJ, Saunders TJ, Sheehan D, Stone MR, Woodruff SJ, Belanger K, Barnes JD, Longmuir PE, Tremblay MS.

BMC Public Health. 2018 Oct 2;18(Suppl 2):1039. doi: 10.1186/s12889-018-5894-7.


A cross-sectional study exploring the relationship between age, gender, and physical measures with adequacy in and predilection for physical activity.

MacDonald DJ, Saunders TJ, Longmuir PE, Barnes JD, Belanger K, Bruner B, Copeland JL, Gregg MJ, Hall N, Kolen AM, Law B, Martin LJ, Sheehan D, Woodruff SJ, Tremblay MS.

BMC Public Health. 2018 Oct 2;18(Suppl 2):1038. doi: 10.1186/s12889-018-5893-8.


Core needle biopsy as an alternative to whole section in IHC4 score assessment for breast cancer prognostication.

Liu M, Tang SX, Tsang JYS, Shi YJ, Ni YB, Law BKB, Tse GMK.

J Clin Pathol. 2018 Dec;71(12):1084-1089. doi: 10.1136/jclinpath-2018-205228. Epub 2018 Sep 18.


The Role of Oxidative Stress and Inflammation in Acute Oxalate Nephropathy Associated With Ethylene Glycol Intoxication.

Wilson GJ, Gois PHF, Zhang A, Wang X, Law BMP, Kassianos AJ, Healy HG.

Kidney Int Rep. 2018 Jun 11;3(5):1217-1221. doi: 10.1016/j.ekir.2018.05.005. eCollection 2018 Sep. No abstract available.


Estimating regional effects of climate change and altered land use on biosphere carbon fluxes using distributed time delay neural networks with Bayesian regularized learning.

Schmidt A, Creason W, Law BE.

Neural Netw. 2018 Dec;108:97-113. doi: 10.1016/j.neunet.2018.08.004. Epub 2018 Aug 16.


N6-methyladenosine contributes to cellular phenotype in a genetically-defined model of breast cancer progression.

Fry NJ, Law BA, Ilkayeva OR, Carraway KR, Holley CL, Mansfield KD.

Oncotarget. 2018 Jul 27;9(58):31231-31243. doi: 10.18632/oncotarget.25782. eCollection 2018 Jul 27.


Circulating miRs-183-5p, -206-3p and -381-3p may serve as novel biomarkers for 4,4'-methylene diphenyl diisocyanate exposure.

Lin CC, Law BF, Siegel PD, Hettick JM.

Biomarkers. 2018 Dec 12:1-15. doi: 10.1080/1354750X.2018.1508308. [Epub ahead of print]


A Method for Rapid Screening of Anilide-Containing AMPK Modulators Based on Computational Docking and Biological Validation.

Mok SWF, Zeng W, Niu Y, Coghi P, Wu Y, Sin WM, Ng SI, Gordillo-Martínez F, Gao JY, Law BYK, Liu L, Yao X, Wong VKW.

Front Pharmacol. 2018 Jul 3;9:710. doi: 10.3389/fphar.2018.00710. eCollection 2018.


Critical role of histone demethylase Jumonji domain-containing protein 3 in the regulation of neointima formation following vascular injury.

Luo X, Yang D, Wu W, Long F, Xiao C, Qin M, Law BY, Suguro R, Xu X, Qu L, Liu X, Zhu YZ.

Cardiovasc Res. 2018 Dec 1;114(14):1894-1906. doi: 10.1093/cvr/cvy176.


Selective Inhibition of Lysine-Specific Demethylase 5A (KDM5A) Using a Rhodium(III) Complex for Triple-Negative Breast Cancer Therapy.

Yang GJ, Wang W, Mok SWF, Wu C, Law BYK, Miao XM, Wu KJ, Zhong HJ, Wong CY, Wong VKW, Ma DL, Leung CH.

Angew Chem Int Ed Engl. 2018 Oct 1;57(40):13091-13095. doi: 10.1002/anie.201807305. Epub 2018 Jul 19.


Effector γδ T cells in human renal fibrosis and chronic kidney disease.

Law BM, Wilkinson R, Wang X, Kildey K, Lindner M, Beagley K, Healy H, Kassianos AJ.

Nephrol Dial Transplant. 2019 Jan 1;34(1):40-48. doi: 10.1093/ndt/gfy098.


Head and Neck Tumors: Amide Proton Transfer MRI.

Law BKH, King AD, Ai QY, Poon DMC, Chen W, Bhatia KS, Ahuja AT, Ma BB, Ka-Wai Yeung D, Fai Mo FK, Wang YX, Yuan J.

Radiology. 2018 Sep;288(3):782-790. doi: 10.1148/radiol.2018171528. Epub 2018 Jun 12.


The unfolded protein response as a target for anticancer therapeutics.

Wang M, Law ME, Castellano RK, Law BK.

Crit Rev Oncol Hematol. 2018 Jul;127:66-79. doi: 10.1016/j.critrevonc.2018.05.003. Epub 2018 May 26. Review.


Quadrivalent human papillomavirus vaccination in girls and the risk of autoimmune disorders: the Ontario Grade 8 HPV Vaccine Cohort Study.

Liu EY, Smith LM, Ellis AK, Whitaker H, Law B, Kwong JC, Farrington P, Lévesque LE.

CMAJ. 2018 May 28;190(21):E648-E655. doi: 10.1503/cmaj.170871.


Loss of sirtuin 1 and mitofusin 2 contributes to enhanced ischemia/reperfusion injury in aged livers.

Chun SK, Lee S, Flores-Toro J, U RY, Yang MJ, Go KL, Biel TG, Miney CE, Pierre Louis S, Law BK, Law ME, Thomas EM, Behrns KE, Leeuwenburgh C, Kim JS.

Aging Cell. 2018 May 17:e12761. doi: 10.1111/acel.12761. [Epub ahead of print]


Staging nodal metastases in nasopharyngeal carcinoma: which method should be used to measure nodal dimension on MRI?

Ai QY, King AD, Mo FKF, Law BKH, Bhatia KS, Poon DMC, Kam MKM, Ma BB.

Clin Radiol. 2018 Jul;73(7):640-646. doi: 10.1016/j.crad.2017.12.015. Epub 2018 Apr 7.


SIRT3 restricts hepatitis B virus transcription and replication through epigenetic regulation of covalently closed circular DNA involving suppressor of variegation 3-9 homolog 1 and SET domain containing 1A histone methyltransferases.

Ren JH, Hu JL, Cheng ST, Yu HB, Wong VKW, Law BYK, Yang YF, Huang Y, Liu Y, Chen WX, Cai XF, Tang H, Hu Y, Zhang WL, Liu X, Long QX, Zhou L, Tao NN, Zhou HZ, Yang QX, Ren F, He L, Gong R, Huang AL, Chen J.

Hepatology. 2018 Oct;68(4):1260-1276. doi: 10.1002/hep.29912. Epub 2018 Jul 25.


Within-species patterns challenge our understanding of the leaf economics spectrum.

Anderegg LDL, Berner LT, Badgley G, Sethi ML, Law BE, HilleRisLambers J.

Ecol Lett. 2018 May;21(5):734-744. doi: 10.1111/ele.12945. Epub 2018 Mar 23.


Land use strategies to mitigate climate change in carbon dense temperate forests.

Law BE, Hudiburg TW, Berner LT, Kent JJ, Buotte PC, Harmon ME.

Proc Natl Acad Sci U S A. 2018 Apr 3;115(14):3663-3668. doi: 10.1073/pnas.1720064115. Epub 2018 Mar 19.


Interspecific differences and commonalities in maternity roosting by tree cavity-roosting bats over a maternity season in a timber production landscape.

Rueegger N, Law B, Goldingay R.

PLoS One. 2018 Mar 15;13(3):e0194429. doi: 10.1371/journal.pone.0194429. eCollection 2018.


Canada's eight-component vaccine safety system: A primer for health care workers.

MacDonald NE, Law BJ.

Paediatr Child Health. 2017 Jul;22(4):e13-e16. doi: 10.1093/pch/pxx073. Epub 2017 Jun 15.


2-Aminoethoxydiphenylborane sensitizes anti-tumor effect of bortezomib via suppression of calcium-mediated autophagy.

Qu YQ, Gordillo-Martinez F, Law BYK, Han Y, Wu A, Zeng W, Lam WK, Ho C, Mok SWF, He HQ, Wong VKW, Wang R.

Cell Death Dis. 2018 Mar 2;9(3):361. doi: 10.1038/s41419-018-0397-0.


The Association between Maternal Stress and Childhood Eczema: A Systematic Review.

Chan CWH, Law BMH, Liu YH, Ambrocio ARB, Au N, Jiang M, Chow KM.

Int J Environ Res Public Health. 2018 Feb 25;15(3). pii: E395. doi: 10.3390/ijerph15030395. Review.


Le système d'innocuité vaccinale canadien en huit étapes : des notions pour les travailleurs de la santé.

MacDonald NE, Law BJ.

Paediatr Child Health. 2017 Jul;22(4):e17-e20. doi: 10.1093/pch/pxx074. Epub 2017 Jun 15.


Le système d'innocuité vaccinale canadien en huit étapes : des notions pour les travailleurs de la santé.

MacDonald NE, Law BJ.

Paediatr Child Health. 2017 Jul;22(4):237. doi: 10.1093/pch/pxx103. Epub 2017 Jun 15.


Canada's eight-component vaccine safety system: A primer for health care workers.

MacDonald NE, Law BJ.

Paediatr Child Health. 2017 Jul;22(4):236. doi: 10.1093/pch/pxx102. Epub 2017 Jun 15.


18F-Radiolabeled Panobinostat Allows for Positron Emission Tomography Guided Delivery of a Histone Deacetylase Inhibitor.

Kommidi H, Tosi U, Maachani UB, Guo H, Marnell CS, Law B, Souweidane MM, Ting R.

ACS Med Chem Lett. 2018 Jan 17;9(2):114-119. doi: 10.1021/acsmedchemlett.7b00471. eCollection 2018 Feb 8.


Forest bat population dynamics over 14 years at a climate refuge: Effects of timber harvesting and weather extremes.

Law BS, Chidel M, Law PR.

PLoS One. 2018 Feb 14;13(2):e0191471. doi: 10.1371/journal.pone.0191471. eCollection 2018.


The Calcium-Induced Regulation in the Molecular and Transcriptional Circuitry of Human Inflammatory Response and Autoimmunity.

de Seabra Rodrigues Dias IR, Mok SWF, Gordillo-Martínez F, Khan I, Hsiao WWL, Law BYK, Wong VKW, Liu L.

Front Pharmacol. 2018 Jan 8;8:962. doi: 10.3389/fphar.2017.00962. eCollection 2017.


MR Imaging Criteria for the Detection of Nasopharyngeal Carcinoma: Discrimination of Early-Stage Primary Tumors from Benign Hyperplasia.

King AD, Wong LYS, Law BKH, Bhatia KS, Woo JKS, Ai QY, Tan TY, Goh J, Chuah KL, Mo FKF, Chan KCA, Chan ATC, Vlantis AC.

AJNR Am J Neuroradiol. 2017 Dec 28. doi: 10.3174/ajnr.A5493. [Epub ahead of print]


Finite-Size and Solvent Dependent Line Tension Effects for Nanoparticles at the Air-Liquid Surface.

Matsubara H, Otsuka J, Law BM.

Langmuir. 2018 Jan 9;34(1):331-340. doi: 10.1021/acs.langmuir.7b03700. Epub 2017 Dec 19.


Nasopharyngeal carcinoma: relationship between invasion of the prevertebral space and distant metastases.

Ai QY, Hu CW, Bhatia KS, Poon DMC, Hui EP, Mo FKF, Law BKH, Tong M, Ma BB, Chan ATC, King AD.

Eur Arch Otorhinolaryngol. 2018 Feb;275(2):497-505. doi: 10.1007/s00405-017-4825-z. Epub 2017 Nov 29.


Novel Strategies on Personalized Medicine for Breast Cancer Treatment: An Update.

Chan CWH, Law BMH, So WKW, Chow KM, Waye MMY.

Int J Mol Sci. 2017 Nov 15;18(11). pii: E2423. doi: 10.3390/ijms18112423. Review.


Lipotoxic very-long-chain ceramides cause mitochondrial dysfunction, oxidative stress, and cell death in cardiomyocytes.

Law BA, Liao X, Moore KS, Southard A, Roddy P, Ji R, Szulc Z, Bielawska A, Schulze PC, Cowart LA.

FASEB J. 2018 Mar;32(3):1403-1416. doi: 10.1096/fj.201700300R. Epub 2018 Jan 3.


Grassystatins D-F, Potent Aspartic Protease Inhibitors from Marine Cyanobacteria as Potential Antimetastatic Agents Targeting Invasive Breast Cancer.

Al-Awadhi FH, Law BK, Paul VJ, Luesch H.

J Nat Prod. 2017 Nov 22;80(11):2969-2986. doi: 10.1021/acs.jnatprod.7b00551. Epub 2017 Oct 31.


A Murine Model for Quantitative, Real-Time Evaluation of Convection-Enhanced Delivery (RT-CED) Using an 18[F]-Positron Emitting, Fluorescent Derivative of Dasatinib.

Wang M, Kommidi H, Tosi U, Guo H, Zhou Z, Schweitzer ME, Wu LY, Singh R, Hou S, Law B, Ting R, Souweidane MM.

Mol Cancer Ther. 2017 Dec;16(12):2902-2912. doi: 10.1158/1535-7163.MCT-17-0423. Epub 2017 Oct 4.


Development and Evaluation of Multimedia Interventions to Promote Breast and Cervical Health among South Asian Women in Hong Kong: A Project Protocol.

So WKW, Chan DNS, Rana T, Law BMH, Leung DYP, Chan HYL, Ng CC, Chair SY, Chan CWH.

Asia Pac J Oncol Nurs. 2017 Oct-Dec;4(4):361-365. doi: 10.4103/apjon.apjon_37_17.

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