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Items: 35

1.

GALAD Score for Hepatocellular Carcinoma Detection in Comparison with Liver Ultrasound and Proposal of GALADUS Score.

Yang JD, Addissie BD, Mara KC, Harmsen WS, Dai J, Zhang N, Wongjarupong N, Ali HM, Ali HA, Hassan FA, Lavu S, Cvinar JL, Giama NH, Moser CD, Miyabe K, Allotey LK, Algeciras-Schimnich A, Theobald JP, Ward MM, Nguyen MH, Befeler AS, Reddy KR, Schwartz M, Harnois DM, Yamada H, Srivastava S, Rinaudo JA, Gores GJ, Feng Z, Marrero JA, Roberts LR.

Cancer Epidemiol Biomarkers Prev. 2019 Mar;28(3):531-538. doi: 10.1158/1055-9965.EPI-18-0281. Epub 2018 Nov 21.

PMID:
30464023
2.

Serum erythropoietin levels in essential thrombocythemia: phenotypic and prognostic correlates.

Szuber N, Lavu S, Mudireddy M, Nicolosi M, Penna D, Vallapureddy RR, Lasho TL, Finke C, Hanson CA, Ketterling RP, Pardanani A, Gangat N, Tefferi A.

Blood Cancer J. 2018 Nov 19;8(12):118. doi: 10.1038/s41408-018-0157-5. No abstract available.

3.

Extramedullary hematopoiesis in the absence of myeloproliferative neoplasm: Mayo Clinic case series of 309 patients.

Fan N, Lavu S, Hanson CA, Tefferi A.

Blood Cancer J. 2018 Nov 19;8(12):119. doi: 10.1038/s41408-018-0156-6. No abstract available.

4.

JAK2 exon 12 mutated polycythemia vera: Mayo-Careggi MPN Alliance study of 33 consecutive cases and comparison with JAK2V617F mutated disease.

Tefferi A, Lavu S, Mudireddy M, Lasho TL, Finke CM, Gangat N, Pardanani A, Hanson CA, Mannarelli C, Guglielmelli P, Vannucchi AM.

Am J Hematol. 2018 Aug;93(4):E93-E96. doi: 10.1002/ajh.25017. No abstract available.

5.

Splanchnic vein thrombosis in patients with myeloproliferative neoplasms: The Mayo clinic experience with 84 consecutive cases.

Lavu S, Szuber N, Mudireddy M, Yogarajah M, Gangat N, Pardanani A, Hanson CA, Ketterling RP, Ashrani AA, Kamath PS, Tefferi A.

Am J Hematol. 2018 Mar;93(3):E61-E64. doi: 10.1002/ajh.24993. Epub 2017 Dec 18. No abstract available.

6.

Cardiac tamponade in myelofibrosis: A Mayo clinic series of nine consecutive cases.

Lavu S, Tefferi A.

Am J Hematol. 2017 Sep;92(9):E544-E545. doi: 10.1002/ajh.24800. Epub 2017 Jul 19. No abstract available.

7.

Discovery of thieno[3,2-d]pyrimidine-6-carboxamides as potent inhibitors of SIRT1, SIRT2, and SIRT3.

Disch JS, Evindar G, Chiu CH, Blum CA, Dai H, Jin L, Schuman E, Lind KE, Belyanskaya SL, Deng J, Coppo F, Aquilani L, Graybill TL, Cuozzo JW, Lavu S, Mao C, Vlasuk GP, Perni RB.

J Med Chem. 2013 May 9;56(9):3666-79. doi: 10.1021/jm400204k. Epub 2013 Apr 29.

PMID:
23570514
8.

Pharmacokinetics and tolerability of SRT2104, a first-in-class small molecule activator of SIRT1, after single and repeated oral administration in man.

Hoffmann E, Wald J, Lavu S, Roberts J, Beaumont C, Haddad J, Elliott P, Westphal C, Jacobson E.

Br J Clin Pharmacol. 2013 Jan;75(1):186-96. doi: 10.1111/j.1365-2125.2012.04340.x.

9.

Discovery of oxazolo[4,5-b]pyridines and related heterocyclic analogs as novel SIRT1 activators.

Bemis JE, Vu CB, Xie R, Nunes JJ, Ng PY, Disch JS, Milne JC, Carney DP, Lynch AV, Jin L, Smith JJ, Lavu S, Iffland A, Jirousek MR, Perni RB.

Bioorg Med Chem Lett. 2009 Apr 15;19(8):2350-3. doi: 10.1016/j.bmcl.2008.11.106. Epub 2008 Dec 6.

PMID:
19303289
10.

Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo.

Smith JJ, Kenney RD, Gagne DJ, Frushour BP, Ladd W, Galonek HL, Israelian K, Song J, Razvadauskaite G, Lynch AV, Carney DP, Johnson RJ, Lavu S, Iffland A, Elliott PJ, Lambert PD, Elliston KO, Jirousek MR, Milne JC, Boss O.

BMC Syst Biol. 2009 Mar 10;3:31. doi: 10.1186/1752-0509-3-31.

11.

Discovery of imidazo[1,2-b]thiazole derivatives as novel SIRT1 activators.

Vu CB, Bemis JE, Disch JS, Ng PY, Nunes JJ, Milne JC, Carney DP, Lynch AV, Smith JJ, Lavu S, Lambert PD, Gagne DJ, Jirousek MR, Schenk S, Olefsky JM, Perni RB.

J Med Chem. 2009 Mar 12;52(5):1275-83. doi: 10.1021/jm8012954.

PMID:
19199480
12.

Sirtuins--novel therapeutic targets to treat age-associated diseases.

Lavu S, Boss O, Elliott PJ, Lambert PD.

Nat Rev Drug Discov. 2008 Oct;7(10):841-53. doi: 10.1038/nrd2665. Review. Erratum in: Nat Rev Drug Discov. 2009 Jun;8(6):516.

PMID:
18827827
13.

Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes.

Milne JC, Lambert PD, Schenk S, Carney DP, Smith JJ, Gagne DJ, Jin L, Boss O, Perni RB, Vu CB, Bemis JE, Xie R, Disch JS, Ng PY, Nunes JJ, Lynch AV, Yang H, Galonek H, Israelian K, Choy W, Iffland A, Lavu S, Medvedik O, Sinclair DA, Olefsky JM, Jirousek MR, Elliott PJ, Westphal CH.

Nature. 2007 Nov 29;450(7170):712-6.

14.

Nampt/PBEF/Visfatin: a regulator of mammalian health and longevity?

Yang H, Lavu S, Sinclair DA.

Exp Gerontol. 2006 Aug;41(8):718-26. Epub 2006 Jul 13. Review.

15.

Design, synthesis, and biological evaluation of sirtinol analogues as class III histone/protein deacetylase (Sirtuin) inhibitors.

Mai A, Massa S, Lavu S, Pezzi R, Simeoni S, Ragno R, Mariotti FR, Chiani F, Camilloni G, Sinclair DA.

J Med Chem. 2005 Dec 1;48(24):7789-95.

PMID:
16302818
16.

Sirtuin activators mimic caloric restriction and delay ageing in metazoans.

Wood JG, Rogina B, Lavu S, Howitz K, Helfand SL, Tatar M, Sinclair D.

Nature. 2004 Aug 5;430(7000):686-9. Epub 2004 Jul 14. Erratum in: Nature. 2004 Sep 2;431(7004):107.

PMID:
15254550
17.

Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis.

Cohen HY, Lavu S, Bitterman KJ, Hekking B, Imahiyerobo TA, Miller C, Frye R, Ploegh H, Kessler BM, Sinclair DA.

Mol Cell. 2004 Mar 12;13(5):627-38.

18.

Yeast life-span extension by calorie restriction is independent of NAD fluctuation.

Anderson RM, Latorre-Esteves M, Neves AR, Lavu S, Medvedik O, Taylor C, Howitz KT, Santos H, Sinclair DA.

Science. 2003 Dec 19;302(5653):2124-2126. doi: 10.1126/science.1088697. Epub 2003 Nov 6.

19.

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan.

Howitz KT, Bitterman KJ, Cohen HY, Lamming DW, Lavu S, Wood JG, Zipkin RE, Chung P, Kisielewski A, Zhang LL, Scherer B, Sinclair DA.

Nature. 2003 Sep 11;425(6954):191-6. Epub 2003 Aug 24.

PMID:
12939617
20.

Cloning, expression and characterization of the CHO cell elongating factor (Cef) from Vibrio cholerae O1.

McCardell BA, Sathyamoorthy V, Michalski J, Lavu S, Kothary M, Livezey J, Kaper JB, Hall R.

Microb Pathog. 2002 Apr;32(4):165-72.

PMID:
12079406
21.

Analysis of the tumor suppressor gene p53 in xeroderma pigmentosum fibroblasts.

Lavu S, Srivastava M, Srivastava SK.

Cancer Lett. 1994 Sep 30;85(1):9-12.

PMID:
7923108
22.

The protective but nonsynergistic effect of dietary beta-carotene and vitamin E on skin tumorigenesis in Skh mice.

Lambert LA, Wamer WG, Wei RR, Lavu S, Chirtel SJ, Kornhauser A.

Nutr Cancer. 1994;21(1):1-12.

PMID:
8183718
23.

The absence of a synergistic protective effect of beta-carotene and vitamin E on skin tumorigenesis in mice.

Lambert LA, Wamer WG, Wei RR, Lavu S, Kornhauser A.

Ann N Y Acad Sci. 1993 Dec 31;691:259-61. No abstract available.

PMID:
8129306
24.

[Reasons for premature dropout of hospitalized patients with pulmonary tuberculosis].

Kolesnikov VV, Lavu SP, Fedorenko EG.

Probl Tuberk. 1990;(10):48-51. Russian. No abstract available.

PMID:
2150441
25.

Molecular cloning of a human monocyte-derived neutrophil chemotactic factor (MDNCF) and the induction of MDNCF mRNA by interleukin 1 and tumor necrosis factor.

Matsushima K, Morishita K, Yoshimura T, Lavu S, Kobayashi Y, Lew W, Appella E, Kung HF, Leonard EJ, Oppenheim JJ.

J Exp Med. 1988 Jun 1;167(6):1883-93.

26.

Molecular cloning and DNA sequence analysis of the human guanine nucleotide-binding protein Go alpha.

Lavu S, Clark J, Swarup R, Matsushima K, Paturu K, Moss J, Kung HF.

Biochem Biophys Res Commun. 1988 Jan 29;150(2):811-5. Erratum in: Biochem Biophys Res Commun 1988 May 31;153(1):487.

PMID:
3124840
27.

Molecular cloning and sequence analysis of two distinct types of Xenopus laevis protein kinase C.

Chen KH, Peng ZG, Lavu S, Kung HF.

Second Messengers Phosphoproteins. 1988-1989;12(5-6):251-60.

PMID:
3272298
28.

Deduced amino acid sequence of bovine retinal Go alpha: similarities to other guanine nucleotide-binding proteins.

Van Meurs KP, Angus CW, Lavu S, Kung HF, Czarnecki SK, Moss J, Vaughan M.

Proc Natl Acad Sci U S A. 1987 May;84(10):3107-11.

30.

Truncation of the c-myb gene by a retroviral integration in an interleukin 3-dependent myeloid leukemia cell line.

Weinstein Y, Ihle JN, Lavu S, Reddy EP.

Proc Natl Acad Sci U S A. 1986 Jul;83(14):5010-4.

31.

Chromosomal abnormalities induced by iodine-125 in mouse germ cells.

Lavu S, Reddy PP, Reddi OS.

Int J Radiat Biol Relat Stud Phys Chem Med. 1985 Oct;48(4):603-7.

PMID:
3876311
32.

Iodine-125 induced micronuclei and sperm head abnormalities in mice.

Lavu S, Reddy PP, Reddi OS.

Int J Radiat Biol Relat Stud Phys Chem Med. 1985 Mar;47(3):249-53.

PMID:
3872277
33.

Activation of the c-myb locus by viral insertional mutagenesis in plasmacytoid lymphosarcomas.

Shen-Ong GL, Potter M, Mushinski JF, Lavu S, Reddy EP.

Science. 1984 Nov 30;226(4678):1077-80.

PMID:
6093260
34.

Dominant lethal induction and testicular uptake of iodine-125 in mice.

Lavu S, Reddy PP, Reddi OS.

Int J Radiat Biol Relat Stud Phys Chem Med. 1984 Apr;45(4):331-43.

PMID:
6609144
35.

Structural organization of mouse c-myb locus and the mechanism of its rearrangement in ABPL-2 tumor line induced by pristane and Abelson murine leukemia virus.

Lavu S, Mushinski JF, Shen-Ong GL, Potter M, Reddy EP.

Curr Top Microbiol Immunol. 1984;113:37-40. No abstract available.

PMID:
6090069

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