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De novo expression of human polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6) in colon adenocarcinoma inhibits the differentiation of colonic epithelium.

Lavrsen K, Dabelsteen S, Vakhrushev SY, Levann AMR, Haue AD, Dylander A, Mandel U, Hansen L, Frödin M, Bennett EP, Wandall HH.

J Biol Chem. 2018 Jan 26;293(4):1298-1314. doi: 10.1074/jbc.M117.812826. Epub 2017 Nov 29.


Glycan elongation beyond the mucin associated Tn antigen protects tumor cells from immune-mediated killing.

Madsen CB, Lavrsen K, Steentoft C, Vester-Christensen MB, Clausen H, Wandall HH, Pedersen AE.

PLoS One. 2013 Sep 6;8(9):e72413. doi: 10.1371/journal.pone.0072413. eCollection 2013. Erratum in: PLoS One. 2013;8(10). doi:10.1371/annotation/81b54c99-e47f-4128-8aeb-b6b3e8c02562.


Precision mapping of the human O-GalNAc glycoproteome through SimpleCell technology.

Steentoft C, Vakhrushev SY, Joshi HJ, Kong Y, Vester-Christensen MB, Schjoldager KT, Lavrsen K, Dabelsteen S, Pedersen NB, Marcos-Silva L, Gupta R, Bennett EP, Mandel U, Brunak S, Wandall HH, Levery SB, Clausen H.

EMBO J. 2013 May 15;32(10):1478-88. doi: 10.1038/emboj.2013.79. Epub 2013 Apr 12.


Cancer associated aberrant protein O-glycosylation can modify antigen processing and immune response.

Madsen CB, Petersen C, Lavrsen K, Harndahl M, Buus S, Clausen H, Pedersen AE, Wandall HH.

PLoS One. 2012;7(11):e50139. doi: 10.1371/journal.pone.0050139. Epub 2012 Nov 26.


Aberrantly glycosylated MUC1 is expressed on the surface of breast cancer cells and a target for antibody-dependent cell-mediated cytotoxicity.

Lavrsen K, Madsen CB, Rasch MG, Woetmann A, Ødum N, Mandel U, Clausen H, Pedersen AE, Wandall HH.

Glycoconj J. 2013 Apr;30(3):227-36. doi: 10.1007/s10719-012-9437-7. Epub 2012 Aug 10.


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