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Items: 1 to 50 of 188

1.

Association of Histologic Disease Activity With Progression of Nonalcoholic Fatty Liver Disease.

Kleiner DE, Brunt EM, Wilson LA, Behling C, Guy C, Contos M, Cummings O, Yeh M, Gill R, Chalasani N, Neuschwander-Tetri BA, Diehl AM, Dasarathy S, Terrault N, Kowdley K, Loomba R, Belt P, Tonascia J, Lavine JE, Sanyal AJ; Nonalcoholic Steatohepatitis Clinical Research Network.

JAMA Netw Open. 2019 Oct 2;2(10):e1912565. doi: 10.1001/jamanetworkopen.2019.12565.

PMID:
31584681
2.

Factors to Consider in Development of Drugs for Pediatric Nonalcoholic Fatty Liver Disease.

Vos MB, Dimick-Santos L, Mehta R, Omokaro SO, Taminiau J, Schabel E, Kleiner DE, Szitanyi P, Socha P, Schwimmer JB, Noviello S, Silberg DG, Torstenson R, Miller V, Lavine JE.

Gastroenterology. 2019 Sep 11. pii: S0016-5085(19)41312-7. doi: 10.1053/j.gastro.2019.08.048. [Epub ahead of print] No abstract available.

PMID:
31520612
3.

Microbiome Signatures Associated With Steatohepatitis and Moderate to Severe Fibrosis in Children With Nonalcoholic Fatty Liver Disease.

Schwimmer JB, Johnson JS, Angeles JE, Behling C, Belt PH, Borecki I, Bross C, Durelle J, Goyal NP, Hamilton G, Holtz ML, Lavine JE, Mitreva M, Newton KP, Pan A, Simpson PM, Sirlin CB, Sodergren E, Tyagi R, Yates KP, Weinstock GM, Salzman NH.

Gastroenterology. 2019 Oct;157(4):1109-1122. doi: 10.1053/j.gastro.2019.06.028. Epub 2019 Jun 27.

PMID:
31255652
4.

Longitudinal ellipsoid zone and subretinal fluid mapping following ocriplasmin injection in the prospective observational ORBIT trial.

Lavine JA, Srivastava SK, Dukles N, Reese JL, Ehlers JP.

Br J Ophthalmol. 2019 Jun 27. pii: bjophthalmol-2019-314142. doi: 10.1136/bjophthalmol-2019-314142. [Epub ahead of print]

PMID:
31248879
5.

Heterogeneity of cultured melanocyte elongation and proliferation factor in bilateral diffuse uveal melanocytic proliferation.

Lavine JA, Ramos MS, Wolk AM, Baynes K, Sharma S, Rachitskaya AV, Anand-Apte B, Srivastava SK, Yuan A.

Exp Eye Res. 2019 Jul;184:30-37. doi: 10.1016/j.exer.2019.04.006. Epub 2019 Apr 10.

PMID:
30978346
6.

Haptoglobin 2 Allele is Associated With Histologic Response to Vitamin E in Subjects With Nonalcoholic Steatohepatitis.

Banini BA, Cazanave SC, Yates KP, Asgharpour A, Vincent R, Mirshahi F, Le P, Contos MJ, Tonascia J, Chalasani NP, Kowdley KV, McCullough AJ, Behling CA, Schwimmer JB, Lavine JE, Sanyal AJ; Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN).

J Clin Gastroenterol. 2019 Nov/Dec;53(10):750-758. doi: 10.1097/MCG.0000000000001142.

PMID:
30586008
7.

IMMUNE RECOVERY UVEITIS-LIKE SYNDROME MIMICKING RECURRENT T-CELL LYMPHOMA AFTER AUTOLOGOUS BONE MARROW TRANSPLANT.

Lavine JA, Singh AD, Baynes K, Srivastava SK.

Retin Cases Brief Rep. 2018 Nov 26. doi: 10.1097/ICB.0000000000000829. [Epub ahead of print]

PMID:
30489451
8.

Hepatocyte Notch activation induces liver fibrosis in nonalcoholic steatohepatitis.

Zhu C, Kim K, Wang X, Bartolome A, Salomao M, Dongiovanni P, Meroni M, Graham MJ, Yates KP, Diehl AM, Schwabe RF, Tabas I, Valenti L, Lavine JE, Pajvani UB.

Sci Transl Med. 2018 Nov 21;10(468). pii: eaat0344. doi: 10.1126/scitranslmed.aat0344.

PMID:
30463916
9.

Hepatic R2* is more strongly associated with proton density fat fraction than histologic liver iron scores in patients with nonalcoholic fatty liver disease.

Bashir MR, Wolfson T, Gamst AC, Fowler KJ, Ohliger M, Shah SN, Alazraki A, Trout AT, Behling C, Allende DS, Loomba R, Sanyal A, Schwimmer J, Lavine JE, Shen W, Tonascia J, Van Natta ML, Mamidipalli A, Hooker J, Kowdley KV, Middleton MS, Sirlin CB; NASH Clinical Research Network (NASH CRN).

J Magn Reson Imaging. 2019 May;49(5):1456-1466. doi: 10.1002/jmri.26312. Epub 2018 Oct 14.

PMID:
30318834
10.

Hepatic Nuclear Receptor Expression Associates with Features of Histology in Pediatric Nonalcoholic Fatty Liver Disease.

Elbel EE, Lavine JE, Downes M, Van Natta M, Yu R, Schwimmer JB, Behling C, Brunt EM, Tonascia J, Evans R.

Hepatol Commun. 2018 Sep 27;2(10):1213-1226. doi: 10.1002/hep4.1232. eCollection 2018 Oct.

11.

ULTRA-WIDEFIELD MULTIMODAL IMAGING OF PRIMARY VITREORETINAL LYMPHOMA.

Lavine JA, Singh AD, Sharma S, Baynes K, Lowder CY, Srivastava SK.

Retina. 2019 Oct;39(10):1861-1871. doi: 10.1097/IAE.0000000000002260.

PMID:
30044267
12.

Exome sequencing of an adolescent with nonalcoholic fatty liver disease identifies a clinically actionable case of Wilson disease.

Wattacheril J, Shea PR, Mohammad S, Behling C, Aggarwal V, Wilson LA, Yates KP, Ito J, Fishbein M, Stong N, Lavine JE, Goldstein DB.

Cold Spring Harb Mol Case Stud. 2018 Oct 1;4(5). pii: a003087. doi: 10.1101/mcs.a003087. Print 2018 Oct.

13.

Pediatric Nonalcoholic Fatty Liver Disease in New York City: An Autopsy Study.

Fernandes DM, Pantangi V, Azam M, Salomao M, Iuga AC, Lefkowitch JH, Gill J, Morotti R, Lavine JE, Mencin AA.

J Pediatr. 2018 Sep;200:174-180. doi: 10.1016/j.jpeds.2018.04.047. Epub 2018 Jun 11.

PMID:
29903531
14.

Alanine Aminotransferase as a Monitoring Biomarker in Children with Nonalcoholic Fatty Liver Disease: A Secondary Analysis Using TONIC Trial Data.

Arsik I, Frediani JK, Frezza D, Chen W, Ayer T, Keskinocak P, Jin R, Konomi JV, Barlow SE, Xanthakos SA, Lavine JE, Vos MB.

Children (Basel). 2018 May 25;5(6). pii: E64. doi: 10.3390/children5060064.

15.

Ventral striatal response during decision making involving risk and reward is associated with future binge drinking in adolescents.

Morales AM, Jones SA, Ehlers A, Lavine JB, Nagel BJ.

Neuropsychopharmacology. 2018 Aug;43(9):1884-1890. doi: 10.1038/s41386-018-0087-8. Epub 2018 May 7.

16.

Clinically Actionable Hypercholesterolemia and Hypertriglyceridemia in Children with Nonalcoholic Fatty Liver Disease.

Harlow KE, Africa JA, Wells A, Belt PH, Behling CA, Jain AK, Molleston JP, Newton KP, Rosenthal P, Vos MB, Xanthakos SA, Lavine JE, Schwimmer JB; Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN).

J Pediatr. 2018 Jul;198:76-83.e2. doi: 10.1016/j.jpeds.2018.02.038. Epub 2018 Apr 13.

17.

Associations of Early to Mid-Childhood Adiposity with Elevated Mid-Childhood Alanine Aminotransferase Levels in the Project Viva Cohort.

Woo Baidal JA, Elbel EE, Lavine JE, Rifas-Shiman SL, Gillman MW, Oken E, Taveras EM.

J Pediatr. 2018 Jun;197:121-127.e1. doi: 10.1016/j.jpeds.2018.01.069. Epub 2018 Apr 4.

18.

Genetic Variants Associated With Obesity and Insulin Resistance in Hispanic Boys With Nonalcoholic Fatty Liver Disease.

Rausch JC, Lavine JE, Chalasani N, Guo X, Kwon S, Schwimmer JB, Molleston JP, Loomba R, Brunt EM, Chen YI, Goodarzi MO, Taylor KD, Yates KP, Rotter JI; NASH Clinical Research Network.

J Pediatr Gastroenterol Nutr. 2018 May;66(5):789-796. doi: 10.1097/MPG.0000000000001926.

19.

Propranolol for Proliferative Diabetic Retinopathy.

Hendrick AM, Lavine JA, Domalpally A, Kulkarni AD, Ip MS.

Ophthalmic Surg Lasers Imaging Retina. 2018 Jan 1;49(1):35-40. doi: 10.3928/23258160-20171215-05.

PMID:
29304264
20.

Convergent neurobiological predictors of emergent psychopathology during adolescence.

Jones SA, Morales AM, Lavine JB, Nagel BJ.

Birth Defects Res. 2017 Dec 1;109(20):1613-1622. doi: 10.1002/bdr2.1176. Review.

21.

Diagnostic modalities for nonalcoholic fatty liver disease, nonalcoholic steatohepatitis, and associated fibrosis.

Younossi ZM, Loomba R, Anstee QM, Rinella ME, Bugianesi E, Marchesini G, Neuschwander-Tetri BA, Serfaty L, Negro F, Caldwell SH, Ratziu V, Corey KE, Friedman SL, Abdelmalek MF, Harrison SA, Sanyal AJ, Lavine JE, Mathurin P, Charlton MR, Goodman ZD, Chalasani NP, Kowdley KV, George J, Lindor K.

Hepatology. 2018 Jul;68(1):349-360. doi: 10.1002/hep.29721.

22.

Current and future therapeutic regimens for nonalcoholic fatty liver disease and nonalcoholic steatohepatitis.

Younossi ZM, Loomba R, Rinella ME, Bugianesi E, Marchesini G, Neuschwander-Tetri BA, Serfaty L, Negro F, Caldwell SH, Ratziu V, Corey KE, Friedman SL, Abdelmalek MF, Harrison SA, Sanyal AJ, Lavine JE, Mathurin P, Charlton MR, Chalasani NP, Anstee QM, Kowdley KV, George J, Goodman ZD, Lindor K.

Hepatology. 2018 Jul;68(1):361-371. doi: 10.1002/hep.29724.

23.

Association Between Cytokines and Liver Histology in Children with Nonalcoholic Fatty Liver Disease.

Perito ER, Ajmera V, Bass NM, Rosenthal P, Lavine JE, Schwimmer JB, Yates KP, Diehl AM, Molleston JP, Murray KF, Scheimann A, Gill R, Glidden D, Aouizerat B.

Hepatol Commun. 2017 Sep;1(7):609-622. doi: 10.1002/hep4.1068. Epub 2017 Jul 17.

24.

Diagnostic accuracy of magnetic resonance imaging hepatic proton density fat fraction in pediatric nonalcoholic fatty liver disease.

Middleton MS, Van Natta ML, Heba ER, Alazraki A, Trout AT, Masand P, Brunt EM, Kleiner DE, Doo E, Tonascia J, Lavine JE, Shen W, Hamilton G, Schwimmer JB, Sirlin CB; NASH Clinical Research Network.

Hepatology. 2018 Mar;67(3):858-872. doi: 10.1002/hep.29596. Epub 2018 Jan 26.

25.

Pediatric Cytochrome P450 Activity Alterations in Nonalcoholic Steatohepatitis.

Li H, Canet MJ, Clarke JD, Billheimer D, Xanthakos SA, Lavine JE, Erickson RP, Cherrington NJ.

Drug Metab Dispos. 2017 Dec;45(12):1317-1325. doi: 10.1124/dmd.117.077644. Epub 2017 Oct 6.

26.

Genome-Wide Associations Related to Hepatic Histology in Nonalcoholic Fatty Liver Disease in Hispanic Boys.

Wattacheril J, Lavine JE, Chalasani NP, Guo X, Kwon S, Schwimmer J, Molleston JP, Loomba R, Brunt EM, Chen YI, Goodarzi MO, Taylor KD, Yates KP, Tonascia J, Rotter JI.

J Pediatr. 2017 Nov;190:100-107.e2. doi: 10.1016/j.jpeds.2017.08.004. Epub 2017 Sep 14.

27.

Tidal Wave Retinal Detachment.

Lavine JA, Kumar JB, Rachitskaya AV.

Ophthalmology. 2017 Aug;124(8):1217. doi: 10.1016/j.ophtha.2017.01.041. No abstract available.

PMID:
28734335
28.

The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases.

Chalasani N, Younossi Z, Lavine JE, Charlton M, Cusi K, Rinella M, Harrison SA, Brunt EM, Sanyal AJ.

Hepatology. 2018 Jan;67(1):328-357. doi: 10.1002/hep.29367. Epub 2017 Sep 29. Review. No abstract available.

PMID:
28714183
29.

Agreement Between Magnetic Resonance Imaging Proton Density Fat Fraction Measurements and Pathologist-Assigned Steatosis Grades of Liver Biopsies From Adults With Nonalcoholic Steatohepatitis.

Middleton MS, Heba ER, Hooker CA, Bashir MR, Fowler KJ, Sandrasegaran K, Brunt EM, Kleiner DE, Doo E, Van Natta ML, Lavine JE, Neuschwander-Tetri BA, Sanyal A, Loomba R, Sirlin CB; NASH Clinical Research Network.

Gastroenterology. 2017 Sep;153(3):753-761. doi: 10.1053/j.gastro.2017.06.005. Epub 2017 Jun 15.

30.

Current Concepts in Pediatric Nonalcoholic Fatty Liver Disease.

Fleet SE, Lefkowitch JH, Lavine JE.

Gastroenterol Clin North Am. 2017 Jun;46(2):217-231. doi: 10.1016/j.gtc.2017.01.002. Review.

PMID:
28506362
31.

Magnetic resonance elastography measured shear stiffness as a biomarker of fibrosis in pediatric nonalcoholic fatty liver disease.

Schwimmer JB, Behling C, Angeles JE, Paiz M, Durelle J, Africa J, Newton KP, Brunt EM, Lavine JE, Abrams SH, Masand P, Krishnamurthy R, Wong K, Ehman RL, Yin M, Glaser KJ, Dzyubak B, Wolfson T, Gamst AC, Hooker J, Haufe W, Schlein A, Hamilton G, Middleton MS, Sirlin CB.

Hepatology. 2017 Nov;66(5):1474-1485. doi: 10.1002/hep.29241. Epub 2017 Oct 9.

32.

Low and High Birth Weights Are Risk Factors for Nonalcoholic Fatty Liver Disease in Children.

Newton KP, Feldman HS, Chambers CD, Wilson L, Behling C, Clark JM, Molleston JP, Chalasani N, Sanyal AJ, Fishbein MH, Lavine JE, Schwimmer JB; Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN).

J Pediatr. 2017 Aug;187:141-146.e1. doi: 10.1016/j.jpeds.2017.03.007. Epub 2017 Mar 30.

33.

In Children With Nonalcoholic Fatty Liver Disease, Zone 1 Steatosis Is Associated With Advanced Fibrosis.

Africa JA, Behling CA, Brunt EM, Zhang N, Luo Y, Wells A, Hou J, Belt PH, Kohil R, Lavine JE, Molleston JP, Newton KP, Whitington PF, Schwimmer JB; Nonalcoholic Steatohepatitis Clinical Research Network.

Clin Gastroenterol Hepatol. 2018 Mar;16(3):438-446.e1. doi: 10.1016/j.cgh.2017.02.030. Epub 2017 Mar 7.

34.

β2-Adrenergic Receptor Antagonism Attenuates CNV Through Inhibition of VEGF and IL-6 Expression.

Lavine JA, Farnoodian M, Wang S, Darjatmoko SR, Wright LS, Gamm DM, Ip MS, Sorenson CM, Sheibani N.

Invest Ophthalmol Vis Sci. 2017 Jan 1;58(1):299-308. doi: 10.1167/iovs.16-20204.

35.

In Children With Nonalcoholic Fatty Liver Disease, Cysteamine Bitartrate Delayed Release Improves Liver Enzymes but Does Not Reduce Disease Activity Scores.

Schwimmer JB, Lavine JE, Wilson LA, Neuschwander-Tetri BA, Xanthakos SA, Kohli R, Barlow SE, Vos MB, Karpen SJ, Molleston JP, Whitington PF, Rosenthal P, Jain AK, Murray KF, Brunt EM, Kleiner DE, Van Natta ML, Clark JM, Tonascia J, Doo E; NASH CRN.

Gastroenterology. 2016 Dec;151(6):1141-1154.e9. doi: 10.1053/j.gastro.2016.08.027. Epub 2016 Aug 26.

36.

Patient Sex, Reproductive Status, and Synthetic Hormone Use Associate With Histologic Severity of Nonalcoholic Steatohepatitis.

Yang JD, Abdelmalek MF, Guy CD, Gill RM, Lavine JE, Yates K, Klair J, Terrault NA, Clark JM, Unalp-Arida A, Diehl AM, Suzuki A; Nonalcoholic Steatohepatitis Clinical Research Network.

Clin Gastroenterol Hepatol. 2017 Jan;15(1):127-131.e2. doi: 10.1016/j.cgh.2016.07.034. Epub 2016 Aug 12.

37.

Prevalence of Prediabetes and Type 2 Diabetes in Children With Nonalcoholic Fatty Liver Disease.

Newton KP, Hou J, Crimmins NA, Lavine JE, Barlow SE, Xanthakos SA, Africa J, Behling C, Donithan M, Clark JM, Schwimmer JB; Nonalcoholic Steatohepatitis Clinical Research Network.

JAMA Pediatr. 2016 Oct 3;170(10):e161971. doi: 10.1001/jamapediatrics.2016.1971. Epub 2016 Oct 3.

38.

Multi-epitope Models Explain How Pre-existing Antibodies Affect the Generation of Broadly Protective Responses to Influenza.

Zarnitsyna VI, Lavine J, Ellebedy A, Ahmed R, Antia R.

PLoS Pathog. 2016 Jun 23;12(6):e1005692. doi: 10.1371/journal.ppat.1005692. eCollection 2016 Jun.

39.

A longer duration of estrogen deficiency increases fibrosis risk among postmenopausal women with nonalcoholic fatty liver disease.

Klair JS, Yang JD, Abdelmalek MF, Guy CD, Gill RM, Yates K, Unalp-Arida A, Lavine JE, Clark JM, Diehl AM, Suzuki A; Nonalcoholic Steatohepatitis Clinical Research Network.

Hepatology. 2016 Jul;64(1):85-91. doi: 10.1002/hep.28514. Epub 2016 Apr 5.

40.

The intersection of nonalcoholic fatty liver disease and obesity.

Woo Baidal JA, Lavine JE.

Sci Transl Med. 2016 Jan 27;8(323):323rv1. doi: 10.1126/scitranslmed.aad8390. Review.

PMID:
26819197
41.

Ocular Safety of Intravitreal Propranolol and Its Efficacy in Attenuation of Choroidal Neovascularization.

Nourinia R, Rezaei Kanavi M, Kaharkaboudi A, Taghavi SI, Aldavood SJ, Darjatmoko SR, Wang S, Gurel Z, Lavine JA, Safi S, Ahmadieh H, Daftarian N, Sheibani N.

Invest Ophthalmol Vis Sci. 2015 Dec;56(13):8228-35. doi: 10.1167/iovs.15-17169.

42.

Geographic atrophy in patients with advanced dry age-related macular degeneration: current challenges and future prospects.

Danis RP, Lavine JA, Domalpally A.

Clin Ophthalmol. 2015 Nov 20;9:2159-74. doi: 10.2147/OPTH.S92359. eCollection 2015. Review.

43.
44.

Cholecystokinin expression in the β-cell leads to increased β-cell area in aged mice and protects from streptozotocin-induced diabetes and apoptosis.

Lavine JA, Kibbe CR, Baan M, Sirinvaravong S, Umhoefer HM, Engler KA, Meske LM, Sacotte KA, Erhardt DP, Davis DB.

Am J Physiol Endocrinol Metab. 2015 Nov 15;309(10):E819-28. doi: 10.1152/ajpendo.00159.2015. Epub 2015 Sep 22.

45.

Caring for children with NAFLD and navigating their care into adulthood.

Mencin AA, Loomba R, Lavine JE.

Nat Rev Gastroenterol Hepatol. 2015 Nov;12(11):617-28. doi: 10.1038/nrgastro.2015.146. Epub 2015 Sep 1. Review.

PMID:
26323878
46.

Multimodal imaging of refractory Candida chorioretinitis progressing to endogenous endophthalmitis.

Lavine JA, Mititelu M.

J Ophthalmic Inflamm Infect. 2015 Dec;5(1):54. doi: 10.1186/s12348-015-0054-z. Epub 2015 Aug 8.

47.

Feasibility of and agreement between MR imaging and spectroscopic estimation of hepatic proton density fat fraction in children with known or suspected nonalcoholic fatty liver disease.

Achmad E, Yokoo T, Hamilton G, Heba ER, Hooker JC, Changchien C, Schroeder M, Wolfson T, Gamst A, Schwimmer JB, Lavine JE, Sirlin CB, Middleton MS.

Abdom Imaging. 2015 Oct;40(8):3084-90. doi: 10.1007/s00261-015-0506-9.

48.

Clinical Model for NASH and Advanced Fibrosis in Adult Patients With Diabetes and NAFLD: Guidelines for Referral in NAFLD.

Bazick J, Donithan M, Neuschwander-Tetri BA, Kleiner D, Brunt EM, Wilson L, Doo E, Lavine J, Tonascia J, Loomba R.

Diabetes Care. 2015 Jul;38(7):1347-55. doi: 10.2337/dc14-1239. Epub 2015 Apr 17.

49.

Improvement in liver histology is associated with reduction in dyslipidemia in children with nonalcoholic fatty liver disease.

Corey KE, Vuppalanchi R, Vos M, Kohli R, Molleston JP, Wilson L, Unalp-Arida A, Cummings OW, Lavine JE, Chalasani N; Nonalcoholic Steatohepatitis Clinical Research Network.

J Pediatr Gastroenterol Nutr. 2015 Mar;60(3):360-7. doi: 10.1097/MPG.0000000000000584.

50.

Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial.

Neuschwander-Tetri BA, Loomba R, Sanyal AJ, Lavine JE, Van Natta ML, Abdelmalek MF, Chalasani N, Dasarathy S, Diehl AM, Hameed B, Kowdley KV, McCullough A, Terrault N, Clark JM, Tonascia J, Brunt EM, Kleiner DE, Doo E; NASH Clinical Research Network.

Lancet. 2015 Mar 14;385(9972):956-65. doi: 10.1016/S0140-6736(14)61933-4. Epub 2014 Nov 7. Erratum in: Lancet. 2015 Mar 14;385(9972):946. Erratum in: Lancet. 2016 Apr 16;387(10028):1618.

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