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Items: 1 to 50 of 350

1.

Relationship between occupational noise exposure and the risk factors of cardiovascular disease in China: A meta-analysis.

Yang Y, Zhang E, Zhang J, Chen S, Yu G, Liu X, Peng C, Lavin MF, Du Z, Shao H.

Medicine (Baltimore). 2018 Jul;97(30):e11720. doi: 10.1097/MD.0000000000011720. Review.

2.

Design and Clinical Verification of Surface-Enhanced Raman Spectroscopy Diagnostic Technology for Individual Cancer Risk Prediction.

Koo KM, Wang J, Richards RS, Farrell A, Yaxley JW, Samaratunga H, Teloken PE, Roberts MJ, Coughlin GD, Lavin MF, Mainwaring PN, Wang Y, Gardiner RA, Trau M.

ACS Nano. 2018 Jul 26. doi: 10.1021/acsnano.8b03698. [Epub ahead of print]

PMID:
30028592
3.

Robot-assisted laparoscopic prostatectomy versus open radical retropubic prostatectomy: 24-month outcomes from a randomised controlled study.

Coughlin GD, Yaxley JW, Chambers SK, Occhipinti S, Samaratunga H, Zajdlewicz L, Teloken P, Dunglison N, Williams S, Lavin MF, Gardiner RA.

Lancet Oncol. 2018 Aug;19(8):1051-1060. doi: 10.1016/S1470-2045(18)30357-7. Epub 2018 Jul 17.

PMID:
30017351
4.

Transplantation of adipose-derived mesenchymal stem cells attenuates pulmonary fibrosis of silicosis via anti-inflammatory and anti-apoptosis effects in rats.

Chen S, Cui G, Peng C, Lavin MF, Sun X, Zhang E, Yang Y, Guan Y, Du Z, Shao H.

Stem Cell Res Ther. 2018 Apr 19;9(1):110. doi: 10.1186/s13287-018-0846-9.

5.

PIKKing a way to regulate inflammation.

Quek H, Lim YC, Lavin MF, Roberts TL.

Immunol Cell Biol. 2018 Jan;96(1):8-20. doi: 10.1111/imcb.1001. Epub 2017 Nov 14. Review.

PMID:
29359354
6.

Seminal plasma enables selection and monitoring of active surveillance candidates using nuclear magnetic resonance-based metabolomics: A preliminary investigation.

Roberts MJ, Richards RS, Chow CWK, Buck M, Yaxley J, Lavin MF, Schirra HJ, Gardiner RA.

Prostate Int. 2017 Dec;5(4):149-157. doi: 10.1016/j.prnil.2017.03.005. Epub 2017 Mar 23.

7.

Human iPSC-Derived Cerebellar Neurons from a Patient with Ataxia-Telangiectasia Reveal Disrupted Gene Regulatory Networks.

Nayler SP, Powell JE, Vanichkina DP, Korn O, Wells CA, Kanjhan R, Sun J, Taft RJ, Lavin MF, Wolvetang EJ.

Front Cell Neurosci. 2017 Oct 13;11:321. doi: 10.3389/fncel.2017.00321. eCollection 2017.

8.

Lentiviral Reprogramming of A-T Patient Fibroblasts to Induced Pluripotent Stem Cells.

Nayler S, Kozlov SV, Lavin MF, Wolvetang E.

Methods Mol Biol. 2017;1599:401-418. doi: 10.1007/978-1-4939-6955-5_29.

PMID:
28477135
9.

A Patient-Specific Stem Cell Model to Investigate the Neurological Phenotype Observed in Ataxia-Telangiectasia.

Stewart R, Wali G, Perry C, Lavin MF, Féron F, Mackay-Sim A, Sutharsan R.

Methods Mol Biol. 2017;1599:391-400. doi: 10.1007/978-1-4939-6955-5_28.

PMID:
28477134
10.

Identification of ATM Protein Kinase Phosphorylation Sites by Mass Spectrometry.

Graham ME, Lavin MF, Kozlov SV.

Methods Mol Biol. 2017;1599:127-144. doi: 10.1007/978-1-4939-6955-5_10.

PMID:
28477116
11.

Assaying for Radioresistant DNA Synthesis, the Hallmark Feature of the Intra-S-Phase Checkpoint Using a DNA Fiber Technique.

Kijas AW, Lavin MF.

Methods Mol Biol. 2017;1599:13-23. doi: 10.1007/978-1-4939-6955-5_2.

PMID:
28477108
12.

Loss of ATM in Airway Epithelial Cells Is Associated with Susceptibility to Oxidative Stress.

Yeo AJ, Fantino E, Czovek D, Wainwright CE, Sly PD, Lavin MF.

Am J Respir Crit Care Med. 2017 Aug 1;196(3):391-393. doi: 10.1164/rccm.201611-2210LE. No abstract available.

PMID:
28207280
13.

A rat model of ataxia-telangiectasia: evidence for a neurodegenerative phenotype.

Quek H, Luff J, Cheung K, Kozlov S, Gatei M, Lee CS, Bellingham MC, Noakes PG, Lim YC, Barnett NL, Dingwall S, Wolvetang E, Mashimo T, Roberts TL, Lavin MF.

Hum Mol Genet. 2017 Jan 1;26(1):109-123. doi: 10.1093/hmg/ddw371.

PMID:
28007901
14.

Rats with a missense mutation in Atm display neuroinflammation and neurodegeneration subsequent to accumulation of cytosolic DNA following unrepaired DNA damage.

Quek H, Luff J, Cheung K, Kozlov S, Gatei M, Lee CS, Bellingham MC, Noakes PG, Lim YC, Barnett NL, Dingwall S, Wolvetang E, Mashimo T, Roberts TL, Lavin MF.

J Leukoc Biol. 2017 Apr;101(4):927-947. doi: 10.1189/jlb.4VMA0716-316R. Epub 2016 Nov 28.

PMID:
27895165
15.

Prostate-based biofluids for the detection of prostate cancer: A comparative study of the diagnostic performance of cell-sourced RNA biomarkers.

Roberts MJ, Richards RS, Chow CW, Doi SA, Schirra HJ, Buck M, Samaratunga H, Perry-Keene J, Payton D, Yaxley J, Lavin MF, Gardiner RA.

Prostate Int. 2016 Sep;4(3):97-102. doi: 10.1016/j.prnil.2016.04.002. Epub 2016 May 5.

16.

Robot-assisted laparoscopic prostatectomy versus open radical retropubic prostatectomy: early outcomes from a randomised controlled phase 3 study.

Yaxley JW, Coughlin GD, Chambers SK, Occhipinti S, Samaratunga H, Zajdlewicz L, Dunglison N, Carter R, Williams S, Payton DJ, Perry-Keene J, Lavin MF, Gardiner RA.

Lancet. 2016 Sep 10;388(10049):1057-1066. doi: 10.1016/S0140-6736(16)30592-X. Epub 2016 Jul 26.

PMID:
27474375
17.

Correction: AarF Domain Containing Kinase 3 (ADCK3) Mutant Cells Display Signs of Oxidative Stress, Defects in Mitochondrial Homeostasis and Lysosomal Accumulation.

Cullen JK, Abdul Murad N, Yeo A, McKenzie M, Ward M, Chong KL, Schieber NL, Parton RG, Lim YC, Wolvetang E, Maghzal GJ, Stocker R, Lavin MF.

PLoS One. 2016 Jul 21;11(7):e0160162. doi: 10.1371/journal.pone.0160162. eCollection 2016.

18.

Can atorvastatin with metformin change the natural history of prostate cancer as characterized by molecular, metabolomic, imaging and pathological variables? A randomized controlled trial protocol.

Roberts MJ, Yaxley JW, Coughlin GD, Gianduzzo TR, Esler RC, Dunglison NT, Chambers SK, Medcraft RJ, Chow CW, Schirra HJ, Richards RS, Kienzle N, Lu M, Brereton I, Samaratunga H, Perry-Keene J, Payton D, Oyama C, Doi SA, Lavin MF, Gardiner RA.

Contemp Clin Trials. 2016 Sep;50:16-20. doi: 10.1016/j.cct.2016.06.014. Epub 2016 Jun 28.

PMID:
27370230
19.

Integrating Molecular Profiling of Liquid Biopsy Samples with a Calculator Algorithm To Detect High-risk Prostate Cancer.

Gardiner RA, Mainwaring P, Lavin MF.

Eur Urol. 2016 Nov;70(5):749-750. doi: 10.1016/j.eururo.2016.05.012. Epub 2016 May 24. No abstract available.

PMID:
27234996
20.

AarF Domain Containing Kinase 3 (ADCK3) Mutant Cells Display Signs of Oxidative Stress, Defects in Mitochondrial Homeostasis and Lysosomal Accumulation.

Cullen JK, Abdul Murad N, Yeo A, McKenzie M, Ward M, Chong KL, Schieber NL, Parton RG, Lim YC, Wolvetang E, Maghzal GJ, Stocker R, Lavin MF.

PLoS One. 2016 Feb 11;11(2):e0148213. doi: 10.1371/journal.pone.0148213. eCollection 2016. Erratum in: PLoS One. 2016;11(7):e0160162.

21.

Characterization and structural analysis of a potent anticoagulant phospholipase A2 from Pseudechis australis snake venom.

Du QS, Trabi M, Richards RS, Mirtschin P, Madaras F, Nouwens A, Zhao KN, de Jersey J, Lavin MF, Guddat LW, Masci PP.

Toxicon. 2016 Mar 1;111:37-49. doi: 10.1016/j.toxicon.2015.12.017. Epub 2015 Dec 30.

PMID:
26747471
22.

ATM-Dependent Phosphorylation of All Three Members of the MRN Complex: From Sensor to Adaptor.

Lavin MF, Kozlov S, Gatei M, Kijas AW.

Biomolecules. 2015 Oct 23;5(4):2877-902. doi: 10.3390/biom5042877. Review.

23.

ATM-dependent phosphorylation of MRE11 controls extent of resection during homology directed repair by signalling through Exonuclease 1.

Kijas AW, Lim YC, Bolderson E, Cerosaletti K, Gatei M, Jakob B, Tobias F, Taucher-Scholz G, Gueven N, Oakley G, Concannon P, Wolvetang E, Khanna KK, Wiesmüller L, Lavin MF.

Nucleic Acids Res. 2015 Sep 30;43(17):8352-67. doi: 10.1093/nar/gkv754. Epub 2015 Aug 3.

24.

A new model to study neurodegeneration in ataxia oculomotor apraxia type 2.

Becherel OJ, Sun J, Yeo AJ, Nayler S, Fogel BL, Gao F, Coppola G, Criscuolo C, De Michele G, Wolvetang E, Lavin MF.

Hum Mol Genet. 2015 Oct 15;24(20):5759-74. doi: 10.1093/hmg/ddv296. Epub 2015 Jul 30.

25.

Senataxin suppresses the antiviral transcriptional response and controls viral biogenesis.

Miller MS, Rialdi A, Ho JS, Tilove M, Martinez-Gil L, Moshkina NP, Peralta Z, Noel J, Melegari C, Maestre AM, Mitsopoulos P, Madrenas J, Heinz S, Benner C, Young JA, Feagins AR, Basler CF, Fernandez-Sesma A, Becherel OJ, Lavin MF, van Bakel H, Marazzi I.

Nat Immunol. 2015 May;16(5):485-94. doi: 10.1038/ni.3132. Epub 2015 Mar 30.

26.

Diagnostic performance of expression of PCA3, Hepsin and miR biomarkers inejaculate in combination with serum PSA for the detection of prostate cancer.

Roberts MJ, Chow CW, Schirra HJ, Richards R, Buck M, Selth LA, Doi SA, Samaratunga H, Perry-Keene J, Payton D, Yaxley J, Lavin MF, Gardiner RA.

Prostate. 2015 Apr 1;75(5):539-49. doi: 10.1002/pros.22942. Epub 2015 Jan 18.

PMID:
25597828
27.

Senataxin controls meiotic silencing through ATR activation and chromatin remodeling.

Yeo AJ, Becherel OJ, Luff JE, Graham ME, Richard D, Lavin MF.

Cell Discov. 2015 Sep 29;1:15025. doi: 10.1038/celldisc.2015.25. eCollection 2015.

28.

β-Adducin siRNA disruption of the spectrin-based cytoskeleton in differentiating keratinocytes prevented by calcium acting through calmodulin/epidermal growth factor receptor/cadherin pathway.

Wu J, Masci PP, Chen C, Chen J, Lavin MF, Zhao KN.

Cell Signal. 2015 Jan;27(1):15-25. doi: 10.1016/j.cellsig.2014.10.001. Epub 2014 Oct 7.

PMID:
25305142
29.

Increased sensitivity to ionizing radiation by targeting the homologous recombination pathway in glioma initiating cells.

Lim YC, Roberts TL, Day BW, Stringer BW, Kozlov S, Fazry S, Bruce ZC, Ensbey KS, Walker DG, Boyd AW, Lavin MF.

Mol Oncol. 2014 Dec;8(8):1603-15. doi: 10.1016/j.molonc.2014.06.012. Epub 2014 Jun 27.

30.

Human seminal fluid as a source of prostate cancer-specific microRNA biomarkers.

Selth LA, Roberts MJ, Chow CW, Marshall VR, Doi SA, Vincent AD, Butler LM, Lavin MF, Tilley WD, Gardiner RA.

Endocr Relat Cancer. 2014 Aug;21(4):L17-21. doi: 10.1530/ERC-14-0234. Epub 2014 May 23. No abstract available.

31.

Mutation of senataxin alters disease-specific transcriptional networks in patients with ataxia with oculomotor apraxia type 2.

Fogel BL, Cho E, Wahnich A, Gao F, Becherel OJ, Wang X, Fike F, Chen L, Criscuolo C, De Michele G, Filla A, Collins A, Hahn AF, Gatti RA, Konopka G, Perlman S, Lavin MF, Geschwind DH, Coppola G.

Hum Mol Genet. 2014 Sep 15;23(18):4758-69. doi: 10.1093/hmg/ddu190. Epub 2014 Apr 23.

32.

RAD50 phosphorylation promotes ATR downstream signaling and DNA restart following replication stress.

Gatei M, Kijas AW, Biard D, Dörk T, Lavin MF.

Hum Mol Genet. 2014 Aug 15;23(16):4232-48. doi: 10.1093/hmg/ddu141. Epub 2014 Apr 2.

PMID:
24694934
33.

R-loops in proliferating cells but not in the brain: implications for AOA2 and other autosomal recessive ataxias.

Yeo AJ, Becherel OJ, Luff JE, Cullen JK, Wongsurawat T, Jenjaroenpun P, Kuznetsov VA, McKinnon PJ, Lavin MF.

PLoS One. 2014 Mar 17;9(3):e90219. doi: 10.1371/journal.pone.0090219. eCollection 2014. Erratum in: PLoS One. 2014;9(8):e105258. Jenjaroenpoon, Piroon [corrected to Jenjaroenpun, Piroon].

34.

Protective role of RAD50 on chromatin bridges during abnormal cytokinesis.

Schröder-Heurich B, Wieland B, Lavin MF, Schindler D, Dörk T.

FASEB J. 2014 Mar;28(3):1331-41. doi: 10.1096/fj.13-236984. Epub 2013 Dec 16.

PMID:
24344331
35.

Loss of caspase-2 augments lymphomagenesis and enhances genomic instability in Atm-deficient mice.

Puccini J, Shalini S, Voss AK, Gatei M, Wilson CH, Hiwase DK, Lavin MF, Dorstyn L, Kumar S.

Proc Natl Acad Sci U S A. 2013 Dec 3;110(49):19920-5. doi: 10.1073/pnas.1311947110. Epub 2013 Nov 18.

36.

A progress report on a prospective randomised trial of open and robotic prostatectomy.

Gardiner RA, Coughlin GD, Yaxley JW, Dunglison NT, Occhipinti S, Younie SJ, Carter RC, Williams SG, Medcraft RJ, Samaratunga HM, Perry-Keene JL, Payton DJ, Lavin MF, Chambers SK.

Eur Urol. 2014 Mar;65(3):512-5. doi: 10.1016/j.eururo.2013.10.031. Epub 2013 Oct 31.

PMID:
24215940
37.

BMCC1 is an AP-2 associated endosomal protein in prostate cancer cells.

Harris JL, Richards RS, Chow CW, Lee S, Kim M, Buck M, Teng L, Clarke R, Gardiner RA, Lavin MF.

PLoS One. 2013 Sep 6;8(9):e73880. doi: 10.1371/journal.pone.0073880. eCollection 2013.

38.

Generating SM(a)RTer compounds for translation termination suppression in A-T and other genetic disorders.

Lavin MF.

Mol Ther. 2013 Sep;21(9):1650-2. doi: 10.1038/mt.2013.177. No abstract available.

39.

Calcium prevents retinoic acid-induced disruption of the spectrin-based cytoskeleton in keratinocytes through the Src/PI3K-p85α/AKT/PKCδ/β-adducin pathways.

Zhao KN, Masci PP, Chen J, Lavin MF.

Cell Calcium. 2013 Sep;54(3):151-62. doi: 10.1016/j.ceca.2013.05.009. Epub 2013 Jul 9.

PMID:
23849428
40.

Genotoxicity of hydroquinone in A549 cells.

Peng C, Arthur D, Liu F, Lee J, Xia Q, Lavin MF, Ng JC.

Cell Biol Toxicol. 2013 Aug;29(4):213-27. doi: 10.1007/s10565-013-9247-0. Epub 2013 Jun 8.

PMID:
23744186
41.

The appropriateness of the mouse model for ataxia-telangiectasia: neurological defects but no neurodegeneration.

Lavin MF.

DNA Repair (Amst). 2013 Aug;12(8):612-9. doi: 10.1016/j.dnarep.2013.04.014. Epub 2013 Jun 2. Review.

PMID:
23731731
42.

Senataxin plays an essential role with DNA damage response proteins in meiotic recombination and gene silencing.

Becherel OJ, Yeo AJ, Stellati A, Heng EY, Luff J, Suraweera AM, Woods R, Fleming J, Carrie D, McKinney K, Xu X, Deng C, Lavin MF.

PLoS Genet. 2013 Apr;9(4):e1003435. doi: 10.1371/journal.pgen.1003435. Epub 2013 Apr 11.

43.

A patient-derived olfactory stem cell disease model for ataxia-telangiectasia.

Stewart R, Kozlov S, Matigian N, Wali G, Gatei M, Sutharsan R, Bellette B, Wraith-Kijas A, Cochrane J, Coulthard M, Perry C, Sinclair K, Mackay-Sim A, Lavin MF.

Hum Mol Genet. 2013 Jun 15;22(12):2495-509. doi: 10.1093/hmg/ddt101. Epub 2013 Mar 7.

PMID:
23474819
44.

The structure of human microplasmin in complex with textilinin-1, an aprotinin-like inhibitor from the Australian brown snake.

Millers EK, Johnson LA, Birrell GW, Masci PP, Lavin MF, de Jersey J, Guddat LW.

PLoS One. 2013;8(1):e54104. doi: 10.1371/journal.pone.0054104. Epub 2013 Jan 15.

45.

Smg1 haploinsufficiency predisposes to tumor formation and inflammation.

Roberts TL, Ho U, Luff J, Lee CS, Apte SH, MacDonald KP, Raggat LJ, Pettit AR, Morrow CA, Waters MJ, Chen P, Woods RG, Thomas GP, St Pierre L, Farah CS, Clarke RA, Brown JA, Lavin MF.

Proc Natl Acad Sci U S A. 2013 Jan 22;110(4):E285-94. doi: 10.1073/pnas.1215696110. Epub 2012 Dec 31.

46.

Senataxin protects the genome: Implications for neurodegeneration and other abnormalities.

Lavin MF, Yeo AJ, Becherel OJ.

Rare Dis. 2013 Jun 6;1:e25230. doi: 10.4161/rdis.25230. eCollection 2013.

47.

Mitochondrial dysfunction in a novel form of autosomal recessive ataxia.

Murad NA, Cullen JK, McKenzie M, Ryan MT, Thorburn D, Gueven N, Kobayashi J, Birrell G, Yang J, Dörk T, Becherel O, Grattan-Smith P, Lavin MF.

Mitochondrion. 2013 May;13(3):235-45. doi: 10.1016/j.mito.2012.11.006. Epub 2012 Nov 22. Review.

PMID:
23178371
48.

A role for homologous recombination and abnormal cell-cycle progression in radioresistance of glioma-initiating cells.

Lim YC, Roberts TL, Day BW, Harding A, Kozlov S, Kijas AW, Ensbey KS, Walker DG, Lavin MF.

Mol Cancer Ther. 2012 Sep;11(9):1863-72. doi: 10.1158/1535-7163.MCT-11-1044. Epub 2012 Jul 6.

49.

A randomised trial of robotic and open prostatectomy in men with localised prostate cancer.

Gardiner RA, Yaxley J, Coughlin G, Dunglison N, Occhipinti S, Younie S, Carter R, Williams S, Medcraft RJ, Bennett N, Lavin MF, Chambers SK.

BMC Cancer. 2012 May 25;12:189. doi: 10.1186/1471-2407-12-189.

50.

Approaches to sensitizing glioblastoma to radiotherapy: use of lentiviral vectors.

Chuah TL, Walker DG, Wei M, Scott S, Lavin MF.

Int J Oncol. 2012 Jun;40(6):1963-9. doi: 10.3892/ijo.2012.1409. Epub 2012 Mar 22.

PMID:
22447336

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