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Items: 1 to 50 of 186

1.

Intrinsic cell-penetrating activity propels Omomyc from proof of concept to viable anti-MYC therapy.

Beaulieu ME, Jauset T, Massó-Vallés D, Martínez-Martín S, Rahl P, Maltais L, Zacarias-Fluck MF, Casacuberta-Serra S, Serrano Del Pozo E, Fiore C, Foradada L, Cano VC, Sánchez-Hervás M, Guenther M, Romero Sanz E, Oteo M, Tremblay C, Martín G, Letourneau D, Montagne M, Morcillo Alonso MÁ, Whitfield JR, Lavigne P, Soucek L.

Sci Transl Med. 2019 Mar 20;11(484). pii: eaar5012. doi: 10.1126/scitranslmed.aar5012.

2.

Validation of training levels in endoscopic endonasal surgery of the skull base.

Lavigne P, Faden D, Gardner PA, Fernandez-Miranda JC, Wang EW, Snyderman CH.

Laryngoscope. 2019 Mar 7. doi: 10.1002/lary.27895. [Epub ahead of print]

PMID:
30843604
3.

Determination of Ligand Binding Affinity and Specificity of Purified START Domains by Thermal Shift Assays Using Circular Dichroism.

Létourneau D, LeHoux JG, Lavigne P.

Methods Mol Biol. 2019;1949:293-306. doi: 10.1007/978-1-4939-9136-5_20.

PMID:
30790263
4.

Immunomodulators in chronic rhinosinusitis.

Lavigne P, Lee SE.

World J Otorhinolaryngol Head Neck Surg. 2018 Nov 10;4(3):186-192. doi: 10.1016/j.wjorl.2018.09.002. eCollection 2018 Sep. Review.

5.

Complications of Nasoseptal Flap Reconstruction: A Systematic Review.

Lavigne P, Faden DL, Wang EW, Snyderman CH.

J Neurol Surg B Skull Base. 2018 Oct;79(Suppl 4):S291-S299. doi: 10.1055/s-0038-1668158. Epub 2018 Aug 20.

PMID:
30210981
6.

Supratotal Resection of Residual Clival Chordoma With Combined Endoscopic Endonasal and Contralateral Transmaxillary Approaches: 2-Dimensional Operative Video.

Lavigne P, Wang EW, Fernandez-Miranda JC.

Oper Neurosurg (Hagerstown). 2019 Mar 1;16(3):E88-E89. doi: 10.1093/ons/opy220.

PMID:
30189024
7.

Angiotensin II cyclic analogs as tools to investigate AT1R biased signaling mechanisms.

St-Pierre D, Cabana J, Holleran BJ, Besserer-Offroy É, Escher E, Guillemette G, Lavigne P, Leduc R.

Biochem Pharmacol. 2018 Aug;154:104-117. doi: 10.1016/j.bcp.2018.04.021. Epub 2018 Apr 20.

PMID:
29684376
8.

Diagnosis and endoscopic endonasal management of nontraumatic pseudoaneurysms of the cranial base.

Faden DL, Hughes MA, Lavigne P, Jankowitz BT, Wang EW, Fernandez-Miranda JC, Gardner PA, Snyderman CH.

Int Forum Allergy Rhinol. 2018 May;8(5):641-647. doi: 10.1002/alr.22080. Epub 2018 Feb 27.

PMID:
29485762
9.

Etiology of Acute Coronary Syndrome after Noncardiac Surgery.

Helwani MA, Amin A, Lavigne P, Rao S, Oesterreich S, Samaha E, Brown JC, Nagele P.

Anesthesiology. 2018 Jun;128(6):1084-1091. doi: 10.1097/ALN.0000000000002107.

10.

Electromechanical properties of human osteoarthritic and asymptomatic articular cartilage are sensitive and early detectors of degeneration.

Hadjab I, Sim S, Karhula SS, Kauppinen S, Garon M, Quenneville E, Lavigne P, Lehenkari PP, Saarakkala S, Buschmann MD.

Osteoarthritis Cartilage. 2018 Mar;26(3):405-413. doi: 10.1016/j.joca.2017.12.002. Epub 2017 Dec 9.

11.

s protein binds ubiquitin to regulate epidermal growth factor receptor endosomal sorting.

Li X, Létourneau D, Holleran B, Leduc R, Lavigne P, Lavoie C.

Proc Natl Acad Sci U S A. 2017 Dec 19;114(51):13477-13482. doi: 10.1073/pnas.1708215114. Epub 2017 Nov 30.

12.

Characterization of Hsp90 Co-Chaperone p23 Cleavage by Caspase-7 Uncovers a Peptidase-Substrate Interaction Involving Intrinsically Disordered Regions.

Martini C, Bédard M, Lavigne P, Denault JB.

Biochemistry. 2017 Sep 26;56(38):5099-5111. doi: 10.1021/acs.biochem.7b00298. Epub 2017 Sep 18.

PMID:
28863261
13.

Development of a Traceability System Based on a SNP Array for Large-Scale Production of High-Value White Spruce (Picea glauca).

Godbout J, Tremblay L, Levasseur C, Lavigne P, Rainville A, Mackay J, Bousquet J, Isabel N.

Front Plant Sci. 2017 Jul 25;8:1264. doi: 10.3389/fpls.2017.01264. eCollection 2017.

14.

Erratum to: Development of an Electromechanical Grade to Assess Human Knee Articular Cartilage Quality.

Sim S, Hadjab I, Garon M, Quenneville E, Lavigne P, Buschmann MD.

Ann Biomed Eng. 2017 Oct;45(10):2422. doi: 10.1007/s10439-017-1887-4. No abstract available.

PMID:
28721491
15.

Development of an Electromechanical Grade to Assess Human Knee Articular Cartilage Quality.

Sim S, Hadjab I, Garon M, Quenneville E, Lavigne P, Buschmann MD.

Ann Biomed Eng. 2017 Oct;45(10):2410-2421. doi: 10.1007/s10439-017-1879-4. Epub 2017 Jun 26. Erratum in: Ann Biomed Eng. 2017 Jul 18;:.

PMID:
28653292
16.

Biophysical characterization of the b-HLH-LZ of ΔMax, an alternatively spliced isoform of Max found in tumor cells: Towards the validation of a tumor suppressor role for the Max homodimers.

Maltais L, Montagne M, Bédard M, Tremblay C, Soucek L, Lavigne P.

PLoS One. 2017 Mar 28;12(3):e0174413. doi: 10.1371/journal.pone.0174413. eCollection 2017.

17.

Structural Insights into c-Myc-interacting Zinc Finger Protein-1 (Miz-1) Delineate Domains Required for DNA Scanning and Sequence-specific Binding.

Bédard M, Roy V, Montagne M, Lavigne P.

J Biol Chem. 2017 Feb 24;292(8):3323-3340. doi: 10.1074/jbc.M116.748699. Epub 2016 Dec 29.

19.

Miz-1 and Max compete to engage c-Myc: implication for the mechanism of inhibition of c-Myc transcriptional activity by Miz-1.

Bédard M, Maltais L, Montagne M, Lavigne P.

Proteins. 2017 Feb;85(2):199-206. doi: 10.1002/prot.25214. Epub 2016 Dec 23.

PMID:
27859590
20.

Design, synthesis, and biological evaluation of CXCR4 ligands.

Mona CE, Besserer-Offroy É, Cabana J, Leduc R, Lavigne P, Heveker N, Marsault É, Escher E.

Org Biomol Chem. 2016 Nov 2;14(43):10298-10311.

PMID:
27752700
21.

E2F1 and TFDP1 Regulate PITX1 Expression in Normal and Osteoarthritic Articular Chondrocytes.

Pellicelli M, Picard C, Wang D, Lavigne P, Moreau A.

PLoS One. 2016 Nov 1;11(11):e0165951. doi: 10.1371/journal.pone.0165951. eCollection 2016. Erratum in: PLoS One. 2016 Nov 23;11(11):e0167530.

22.

Structure-Activity Relationship and Signaling of New Chimeric CXCR4 Agonists.

Mona CE, Besserer-Offroy É, Cabana J, Lefrançois M, Boulais PE, Lefebvre MR, Leduc R, Lavigne P, Heveker N, Marsault É, Escher E.

J Med Chem. 2016 Aug 25;59(16):7512-24. doi: 10.1021/acs.jmedchem.6b00566. Epub 2016 Aug 11.

PMID:
27434274
23.

STARD6 on steroids: solution structure, multiple timescale backbone dynamics and ligand binding mechanism.

Létourneau D, Bédard M, Cabana J, Lefebvre A, LeHoux JG, Lavigne P.

Sci Rep. 2016 Jun 24;6:28486. doi: 10.1038/srep28486.

24.

Modified Facial Artery Musculomucosal Flap for Reconstruction of Posterior Skull Base Defects.

Xie L, Lavigne P, Lavigne F, Ayad T.

J Neurol Surg Rep. 2016 Jun;77(2):e98-e101. doi: 10.1055/s-0036-1579630.

25.

Electromechanical probe and automated indentation maps are sensitive techniques in assessing early degenerated human articular cartilage.

Sim S, Chevrier A, Garon M, Quenneville E, Lavigne P, Yaroshinsky A, Hoemann CD, Buschmann MD.

J Orthop Res. 2017 Apr;35(4):858-867. doi: 10.1002/jor.23330. Epub 2016 Jun 22.

26.

Sustained Inner Ear Steroid Delivery via Bioabsorbable Stent: A Tolerability and Feasibility Study on Guinea Pigs.

Lavigne P, Lavigne F, Saliba I.

Otolaryngol Head Neck Surg. 2016 Oct;155(4):649-53. doi: 10.1177/0194599816651262. Epub 2016 May 24.

PMID:
27221576
27.

Solution structure of the 13th C2H2 Zinc Finger of Miz-1.

Tremblay C, Bédard M, Bonin MA, Lavigne P.

Biochem Biophys Res Commun. 2016 Apr 29;473(2):471-5. doi: 10.1016/j.bbrc.2016.03.034. Epub 2016 Mar 10.

PMID:
26972249
28.

GGA3 mediates TrkA endocytic recycling to promote sustained Akt phosphorylation and cell survival.

Li X, Lavigne P, Lavoie C.

Mol Biol Cell. 2015 Dec 1;26(24):4412-26. doi: 10.1091/mbc.E15-02-0087. Epub 2015 Oct 7.

29.

Effects of Fluticasone Furoate on Clinical and Immunological Outcomes (IL-17) for Patients With Nasal Polyposis Naive to Steroid Treatment.

Venkatesan N, Lavigne P, Lavigne F, Hamid Q.

Ann Otol Rhinol Laryngol. 2016 Mar;125(3):213-8. doi: 10.1177/0003489415606449. Epub 2015 Sep 24.

PMID:
26405064
30.

Intratympanic corticosteroids injections: a systematic review of literature.

Lavigne P, Lavigne F, Saliba I.

Eur Arch Otorhinolaryngol. 2016 Sep;273(9):2271-8. doi: 10.1007/s00405-015-3689-3. Epub 2015 Jun 23. Review.

PMID:
26100030
31.

Identification of Distinct Conformations of the Angiotensin-II Type 1 Receptor Associated with the Gq/11 Protein Pathway and the β-Arrestin Pathway Using Molecular Dynamics Simulations.

Cabana J, Holleran B, Leduc R, Escher E, Guillemette G, Lavigne P.

J Biol Chem. 2015 Jun 19;290(25):15835-54. doi: 10.1074/jbc.M114.627356. Epub 2015 May 1.

32.

Impact on Patient Management and Outcome of Switching between 2 Contemporary Sensitive Cardiac Troponin Assays.

Wilen CB, Szymanski JJ, Hung S, Rajan A, Lavigne PM, Char DM, Geltman EM, Scott MG.

Clin Chem. 2015 Jun;61(6):870-6. doi: 10.1373/clinchem.2015.238089. Epub 2015 Apr 17.

33.

Characterization of Angiotensin II Molecular Determinants Involved in AT1 Receptor Functional Selectivity.

Domazet I, Holleran BJ, Richard A, Vandenberghe C, Lavigne P, Escher E, Leduc R, Guillemette G.

Mol Pharmacol. 2015 Jun;87(6):982-95. doi: 10.1124/mol.114.097337. Epub 2015 Mar 25.

PMID:
25808928
34.

Mode of binding of the cyclic agonist peptide TC14012 to CXCR7: identification of receptor and compound determinants.

Montpas N, Cabana J, St-Onge G, Gravel S, Morin G, Kuroyanagi T, Lavigne P, Fujii N, Oishi S, Heveker N.

Biochemistry. 2015 Feb 24;54(7):1505-15. doi: 10.1021/bi501526s. Epub 2015 Feb 11.

PMID:
25669416
35.

The binding site specificity of STARD4 subfamily: Breaking the cholesterol paradigm.

Létourneau D, Lefebvre A, Lavigne P, LeHoux JG.

Mol Cell Endocrinol. 2015 Jun 15;408:53-61. doi: 10.1016/j.mce.2014.12.016. Epub 2014 Dec 24. Review.

PMID:
25542846
36.

Identification of transmembrane domain 1 & 2 residues that contribute to the formation of the ligand-binding pocket of the urotensin-II receptor.

Sainsily X, Cabana J, Holleran BJ, Escher E, Lavigne P, Leduc R.

Biochem Pharmacol. 2014 Nov 15;92(2):280-8. doi: 10.1016/j.bcp.2014.08.023. Epub 2014 Aug 29.

PMID:
25175740
37.

Total knee arthroplasty with a novel navigation system within the surgical field.

Scuderi GR, Fallaha M, Masse V, Lavigne P, Amiot LP, Berthiaume MJ.

Orthop Clin North Am. 2014 Apr;45(2):167-73. doi: 10.1016/j.ocl.2013.11.002. Epub 2014 Jan 16. Review.

PMID:
24684910
38.

Aβ induces its own prion protein N-terminal fragment (PrPN1)-mediated neutralization in amorphous aggregates.

Béland M, Bédard M, Tremblay G, Lavigne P, Roucou X.

Neurobiol Aging. 2014 Jul;35(7):1537-48. doi: 10.1016/j.neurobiolaging.2014.02.001. Epub 2014 Feb 6.

PMID:
24602510
39.

Identification of transmembrane domain 3, 4 & 5 residues that contribute to the formation of the ligand-binding pocket of the urotensin-II receptor.

Sainsily X, Cabana J, Boulais PE, Holleran BJ, Escher E, Lavigne P, Leduc R.

Biochem Pharmacol. 2013 Dec 1;86(11):1584-93. doi: 10.1016/j.bcp.2013.09.015. Epub 2013 Sep 29.

PMID:
24084430
40.

Effect of topical corticosteroids on allergic airway inflammation and disease severity in obstructive sleep apnoea.

Lavigne F, Petrof BJ, Johnson JR, Lavigne P, Binothman N, Kassissia GO, Al Samri M, Giordano C, Dubé N, Hercz D, Benedetti A, Hamid Q.

Clin Exp Allergy. 2013 Oct;43(10):1124-33. doi: 10.1111/cea.12158.

PMID:
24074330
41.

The landscape of nucleotide polymorphism among 13,500 genes of the conifer picea glauca, relationships with functions, and comparison with medicago truncatula.

Pavy N, Deschênes A, Blais S, Lavigne P, Beaulieu J, Isabel N, Mackay J, Bousquet J.

Genome Biol Evol. 2013;5(10):1910-25. doi: 10.1093/gbe/evt143.

42.

Methods for the expression, purification, preparation, and biophysical characterization of constructs of the c-Myc and Max b-HLH-LZs.

Beaulieu ME, McDuff FO, Bédard M, Montagne M, Lavigne P.

Methods Mol Biol. 2013;1012:7-20. doi: 10.1007/978-1-62703-429-6_2.

PMID:
24006055
43.

Structural and dynamical characterization of the Miz-1 zinc fingers 5-8 by solution-state NMR.

Bernard D, Bédard M, Bilodeau J, Lavigne P.

J Biomol NMR. 2013 Oct;57(2):103-16. doi: 10.1007/s10858-013-9770-6. Epub 2013 Aug 24.

PMID:
23975355
44.

Thermodynamic and solution state NMR characterization of the binding of secondary and conjugated bile acids to STARD5.

Létourneau D, Lorin A, Lefebvre A, Cabana J, Lavigne P, LeHoux JG.

Biochim Biophys Acta. 2013 Nov;1831(11):1589-99. doi: 10.1016/j.bbalip.2013.07.005. Epub 2013 Jul 16.

PMID:
23872533
45.

Electroarthrography: a novel method to assess articular cartilage and diagnose osteoarthritis by non-invasive measurement of load-induced electrical potentials at the surface of the knee.

Préville AM, Lavigne P, Buschmann MD, Hardin J, Han Q, Djerroud L, Savard P.

Osteoarthritis Cartilage. 2013 Nov;21(11):1731-7. doi: 10.1016/j.joca.2013.07.003. Epub 2013 Jul 9.

46.

Structure of the human angiotensin II type 1 (AT1) receptor bound to angiotensin II from multiple chemoselective photoprobe contacts reveals a unique peptide binding mode.

Fillion D, Cabana J, Guillemette G, Leduc R, Lavigne P, Escher E.

J Biol Chem. 2013 Mar 22;288(12):8187-97. doi: 10.1074/jbc.M112.442053. Epub 2013 Feb 5.

47.

Development of high-density SNP genotyping arrays for white spruce (Picea glauca) and transferability to subtropical and nordic congeners.

Pavy N, Gagnon F, Rigault P, Blais S, Deschênes A, Boyle B, Pelgas B, Deslauriers M, Clément S, Lavigne P, Lamothe M, Cooke JE, Jaramillo-Correa JP, Beaulieu J, Isabel N, Mackay J, Bousquet J.

Mol Ecol Resour. 2013 Mar;13(2):324-36. doi: 10.1111/1755-0998.12062. Epub 2013 Jan 25.

PMID:
23351128
48.

STARD5 specific ligand binding: comparison with STARD1 and STARD4 subfamilies.

Létourneau D, Lefebvre A, Lavigne P, LeHoux JG.

Mol Cell Endocrinol. 2013 May 22;371(1-2):20-5. doi: 10.1016/j.mce.2013.01.004. Epub 2013 Jan 19. Review.

PMID:
23337244
49.

Nuclear accumulation of prohibitin 1 in osteoarthritic chondrocytes down-regulates PITX1 expression.

Picard C, Pellicelli M, Taheri M, Lavoie JF, Doucet R, Wang D, Bernard L, Bouhanik S, Lavigne P, Moreau A.

Arthritis Rheum. 2013 Apr;65(4):993-1003. doi: 10.1002/art.37837.

50.

The current state of niacin in cardiovascular disease prevention: a systematic review and meta-regression.

Lavigne PM, Karas RH.

J Am Coll Cardiol. 2013 Jan 29;61(4):440-446. doi: 10.1016/j.jacc.2012.10.030. Epub 2012 Dec 19.

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