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Items: 1 to 50 of 112

1.

How to unveil self-quenched fluorophores and subsequently map the subcellular distribution of exogenous peptides.

Swiecicki JM, Thiebaut F, Di Pisa M, Gourdin-Bertin S, Tailhades J, Mansuy C, Burlina F, Chwetzoff S, Trugnan G, Chassaing G, Lavielle S.

Sci Rep. 2016 Feb 3;6:20237. doi: 10.1038/srep20237.

2.

Multi-Stage Mass Spectrometry Analysis of Sugar-Conjugated β-Turn Structures to be Used as Probes in Autoimmune Diseases.

Giangrande C, Auberger N, Rentier C, Papini AM, Mallet JM, Lavielle S, Vinh J.

J Am Soc Mass Spectrom. 2016 Apr;27(4):735-47. doi: 10.1007/s13361-015-1321-9. Epub 2016 Jan 4.

PMID:
26729456
3.

Peptides in Paris.

Papini AM, Lavielle S, Lubell WD; Co-editors and PIPS organizers.

Biopolymers. 2015 Sep;104(5):v-vii. doi: 10.1002/bip.22738. No abstract available.

PMID:
26400823
4.

Unsaturated acyl chains dramatically enhanced cellular uptake by direct translocation of a minimalist oligo-arginine lipopeptide.

Swiecicki JM, Di Pisa M, Lippi F, Chwetzoff S, Mansuy C, Trugnan G, Chassaing G, Lavielle S, Burlina F.

Chem Commun (Camb). 2015 Oct 7;51(78):14656-9. doi: 10.1039/c5cc06116d.

PMID:
26291669
5.

A Pathway Toward Tumor Cell-Selective CPPs?

Alves ID, Carré M, Lavielle S.

Methods Mol Biol. 2015;1324:279-301. doi: 10.1007/978-1-4939-2806-4_18.

PMID:
26202276
6.

Identification of an anti-inflammatory protein from Faecalibacterium prausnitzii, a commensal bacterium deficient in Crohn's disease.

Quévrain E, Maubert MA, Michon C, Chain F, Marquant R, Tailhades J, Miquel S, Carlier L, Bermúdez-Humarán LG, Pigneur B, Lequin O, Kharrat P, Thomas G, Rainteau D, Aubry C, Breyner N, Afonso C, Lavielle S, Grill JP, Chassaing G, Chatel JM, Trugnan G, Xavier R, Langella P, Sokol H, Seksik P.

Gut. 2016 Mar;65(3):415-425. doi: 10.1136/gutjnl-2014-307649. Epub 2015 Jun 4.

7.

Antibody recognition in multiple sclerosis and Rett syndrome using a collection of linear and cyclic N-glucosylated antigenic probes.

Real Fernández F, Di Pisa M, Rossi G, Auberger N, Lequin O, Larregola M, Benchohra A, Mansuy C, Chassaing G, Lolli F, Hayek J, Lavielle S, Rovero P, Mallet JM, Papini AM.

Biopolymers. 2015 Sep;104(5):560-76. doi: 10.1002/bip.22677.

PMID:
25973844
8.

Accumulation of cell-penetrating peptides in large unilamellar vesicles: A straightforward screening assay for investigating the internalization mechanism.

Swiecicki JM, Di Pisa M, Burlina F, Lécorché P, Mansuy C, Chassaing G, Lavielle S.

Biopolymers. 2015 Sep;104(5):533-43. doi: 10.1002/bip.22652.

PMID:
25846422
9.

Glaser oxidative coupling on peptides: stabilization of β-turn structure via a 1,3-butadiyne constraint.

Auberger N, Di Pisa M, Larregola M, Chassaing G, Peroni E, Lavielle S, Papini AM, Lequin O, Mallet JM.

Bioorg Med Chem. 2014 Dec 15;22(24):6924-32. doi: 10.1016/j.bmc.2014.10.026. Epub 2014 Oct 22.

PMID:
25456082
10.

Immune dysfunction in Rett syndrome patients revealed by high levels of serum anti-N(Glc) IgM antibody fraction.

Papini AM, Nuti F, Real-Fernandez F, Rossi G, Tiberi C, Sabatino G, Pandey S, Leoncini S, Signorini C, Pecorelli A, Guerranti R, Lavielle S, Ciccoli L, Rovero P, De Felice C, Hayek J.

J Immunol Res. 2014;2014:260973. doi: 10.1155/2014/260973. Epub 2014 Oct 15.

11.

A proapoptotic peptide conjugated to penetratin selectively inhibits tumor cell growth.

Alves ID, Carré M, Montero MP, Castano S, Lecomte S, Marquant R, Lecorché P, Burlina F, Schatz C, Sagan S, Chassaing G, Braguer D, Lavielle S.

Biochim Biophys Acta. 2014 Aug;1838(8):2087-98. doi: 10.1016/j.bbamem.2014.04.025. Epub 2014 May 2.

12.

The efficacies of cell-penetrating peptides in accumulating in large unilamellar vesicles depend on their ability to form inverted micelles.

Swiecicki JM, Bartsch A, Tailhades J, Di Pisa M, Heller B, Chassaing G, Mansuy C, Burlina F, Lavielle S.

Chembiochem. 2014 Apr 14;15(6):884-91. doi: 10.1002/cbic.201300742. Epub 2014 Feb 23.

PMID:
24677480
13.

Multivalent Interactions: Synthesis and Evaluation of Melanotropin Multimers - Tools for Melanoma Targeting.

Brabez N, Saunders K, Nguyen KL, Jayasundera TB, Weber C, Lynch RM, Chassaing G, Lavielle S, Hruby VJ.

ACS Med Chem Lett. 2013 Jan 1;4(1):98-102. Epub 2012 Nov 24.

14.

Synthesis and evaluation of cholecystokinin trimers: a multivalent approach to pancreatic cancer detection and treatment.

Brabez N, Nguyen KL, Saunders K, Lacy R, Xu L, Gillies RJ, Lynch RM, Chassaing G, Lavielle S, Hruby VJ.

Bioorg Med Chem Lett. 2013 Apr 15;23(8):2422-5. doi: 10.1016/j.bmcl.2013.02.022. Epub 2013 Feb 13.

15.

Self-assembling mini cell-penetrating peptides enter by both direct translocation and glycosaminoglycan-dependent endocytosis.

Bode SA, Thévenin M, Bechara C, Sagan S, Bregant S, Lavielle S, Chassaing G, Burlina F.

Chem Commun (Camb). 2012 Jul 21;48(57):7179-81. doi: 10.1039/c2cc33240j. Epub 2012 Jun 13.

PMID:
22692031
16.

Local control of the cis-trans isomerization and backbone dihedral angles in peptides using trifluoromethylated pseudoprolines.

Feytens D, Chaume G, Chassaing G, Lavielle S, Brigaud T, Byun BJ, Kang YK, Miclet E.

J Phys Chem B. 2012 Apr 5;116(13):4069-79. doi: 10.1021/jp300284u. Epub 2012 Mar 22.

PMID:
22397724
17.

Cellular uptake and biophysical properties of galactose and/or tryptophan containing cell-penetrating peptides.

Lécorché P, Walrant A, Burlina F, Dutot L, Sagan S, Mallet JM, Desbat B, Chassaing G, Alves ID, Lavielle S.

Biochim Biophys Acta. 2012 Mar;1818(3):448-57. doi: 10.1016/j.bbamem.2011.12.003. Epub 2011 Dec 13.

18.

Design, synthesis, and biological studies of efficient multivalent melanotropin ligands: tools toward melanoma diagnosis and treatment.

Brabez N, Lynch RM, Xu L, Gillies RJ, Chassaing G, Lavielle S, Hruby VJ.

J Med Chem. 2011 Oct 27;54(20):7375-84. doi: 10.1021/jm2009937. Epub 2011 Oct 3.

19.

Nanodiamond as a vector for siRNA delivery to Ewing sarcoma cells.

Alhaddad A, Adam MP, Botsoa J, Dantelle G, Perruchas S, Gacoin T, Mansuy C, Lavielle S, Malvy C, Treussart F, Bertrand JR.

Small. 2011 Nov 4;7(21):3087-95. doi: 10.1002/smll.201101193. Epub 2011 Sep 12. Erratum in: Small. 2012 Dec 7;8(23):3549.

PMID:
21913326
20.

β-Amino acids containing peptides and click-cyclized peptide as β-turn mimics: a comparative study with 'conventional' lactam- and disulfide-bridged hexapeptides.

Larregola M, Lequin O, Karoyan P, Guianvarc'h D, Lavielle S.

J Pept Sci. 2011 Sep;17(9):632-43. doi: 10.1002/psc.1382. Epub 2011 Jun 6.

PMID:
21644250
21.

The combination of prolinoamino acids and cyclopropylamino acids leads to fully functionalized, stable β-turns in water.

Guitot K, Larregola M, Pradhan TK, Vasse JL, Lavielle S, Bertus P, Szymoniak J, Lequin O, Karoyan P.

Chembiochem. 2011 May 2;12(7):1039-42. doi: 10.1002/cbic.201000707. Epub 2011 Mar 29. No abstract available.

PMID:
21448869
22.

First Quantitative Imaging of Organic Fluorine within Angiogenic Tissues by Particle Induced Gamma-Ray Emission (PIGE) Analysis: First PIGE Organic Fluorine Imaging.

Lavielle S, Gionnet K, Ortega R, Devès G, Kilarski V, Wehbe K, Bikfalvi A, Déléris G.

Pharmaceutics. 2011 Mar 9;3(1):88-106. doi: 10.3390/pharmaceutics3010088.

23.

Radical stability directs electron capture and transfer dissociation of β-amino acids in peptides.

Ben Hamidane H, Vorobyev A, Larregola M, Lukaszuk A, Tourwé D, Lavielle S, Karoyan P, Tsybin YO.

Chemistry. 2010 Apr 19;16(15):4612-22. doi: 10.1002/chem.200902480. Epub 2010 Mar 16.

PMID:
20235239
24.

Comparing lipid photo-cross-linking efficacy of penetratin analogues bearing three different photoprobes: dithienyl ketone, benzophenone, and trifluoromethylaryldiazirine.

Jiao CY, Alves ID, Point V, Lavielle S, Sagan S, Chassaing G.

Bioconjug Chem. 2010 Feb 17;21(2):352-9. doi: 10.1021/bc900466q.

PMID:
20088542
25.

Cell-penetrating peptides with intracellular actin-remodeling activity in malignant fibroblasts.

Delaroche D, Cantrelle FX, Subra F, Van Heijenoort C, Guittet E, Jiao CY, Blanchoin L, Chassaing G, Lavielle S, Auclair C, Sagan S.

J Biol Chem. 2010 Mar 5;285(10):7712-21. doi: 10.1074/jbc.M109.045872. Epub 2009 Dec 27.

26.

Prolinoamino acids as tools to build bifunctionalized, stable beta-turns in water.

Mothes C, Larregola M, Quancard J, Goasdoué N, Lavielle S, Chassaing G, Lequin O, Karoyan P.

Chembiochem. 2010 Jan 4;11(1):55-8. doi: 10.1002/cbic.200900572. No abstract available.

PMID:
19937896
27.

MALDI-TOF mass spectrometry: a powerful tool to study the internalization of cell-penetrating peptides.

Aubry S, Aussedat B, Delaroche D, Jiao CY, Bolbach G, Lavielle S, Chassaing G, Sagan S, Burlina F.

Biochim Biophys Acta. 2010 Dec;1798(12):2182-9. doi: 10.1016/j.bbamem.2009.11.011. Epub 2009 Nov 22. Review.

28.

Glycosylated cell-penetrating peptides and their conjugates to a proapoptotic peptide: preparation by click chemistry and cell viability studies.

Dutot L, Lécorché P, Burlina F, Marquant R, Point V, Sagan S, Chassaing G, Mallet JM, Lavielle S.

J Chem Biol. 2009 Nov 10;3(2):51-65. doi: 10.1007/s12154-009-0031-9.

29.

Lipid reorganization induced by membrane-active peptides probed using differential scanning calorimetry.

Joanne P, Galanth C, Goasdoué N, Nicolas P, Sagan S, Lavielle S, Chassaing G, El Amri C, Alves ID.

Biochim Biophys Acta. 2009 Sep;1788(9):1772-81. doi: 10.1016/j.bbamem.2009.05.001. Epub 2009 May 7.

30.

Cell-surface thiols affect cell entry of disulfide-conjugated peptides.

Aubry S, Burlina F, Dupont E, Delaroche D, Joliot A, Lavielle S, Chassaing G, Sagan S.

FASEB J. 2009 Sep;23(9):2956-67. doi: 10.1096/fj.08-127563. Epub 2009 Apr 27.

PMID:
19403512
31.

The interaction of cell-penetrating peptides with lipid model systems and subsequent lipid reorganization: thermodynamic and structural characterization.

Alves ID, Correia I, Jiao CY, Sachon E, Sagan S, Lavielle S, Tollin G, Chassaing G.

J Pept Sci. 2009 Mar;15(3):200-9. doi: 10.1002/psc.1070.

PMID:
18985709
32.

Peptide-grafted nanodiamonds: preparation, cytotoxicity and uptake in cells.

Vial S, Mansuy C, Sagan S, Irinopoulou T, Burlina F, Boudou JP, Chassaing G, Lavielle S.

Chembiochem. 2008 Sep 1;9(13):2113-9. doi: 10.1002/cbic.200800247.

PMID:
18677739
33.

Amino-zinc-ene-enolate cyclization: a short access to cis-3-substituted prolino-homotryptophane derivatives.

Mothes C, Lavielle S, Karoyan P.

J Org Chem. 2008 Sep 5;73(17):6706-10. doi: 10.1021/jo801006a. Epub 2008 Jul 26.

PMID:
18656982
34.

Membrane interaction and perturbation mechanisms induced by two cationic cell penetrating peptides with distinct charge distribution.

Alves ID, Goasdoué N, Correia I, Aubry S, Galanth C, Sagan S, Lavielle S, Chassaing G.

Biochim Biophys Acta. 2008 Jul-Aug;1780(7-8):948-59. doi: 10.1016/j.bbagen.2008.04.004. Epub 2008 May 2.

PMID:
18498774
35.

Modifications in the chemical structure of Trojan carriers: impact on cargo delivery.

Aussedat B, Dupont E, Sagan S, Joliot A, Lavielle S, Chassaing G, Burlina F.

Chem Commun (Camb). 2008 Mar 28;(12):1398-400. doi: 10.1039/b800433a. Epub 2008 Feb 22.

PMID:
18338035
36.

[Tracking Trojan peptides in cells].

Sagan S, Burlina F, Delaroche D, Aussedat B, Aubry S, Bolbach G, Lavielle S, Chassaing G.

J Soc Biol. 2006;200(3):213-9. Review. French.

PMID:
17417135
37.

Analysis of an intact G-protein coupled receptor by MALDI-TOF mass spectrometry: molecular heterogeneity of the tachykinin NK-1 receptor.

Alves ID, Sachon E, Bolbach G, Millstine L, Lavielle S, Sagan S.

Anal Chem. 2007 Mar 15;79(6):2189-98. Epub 2007 Feb 13.

PMID:
17295451
38.

Tracking a new cell-penetrating (W/R) nonapeptide, through an enzyme-stable mass spectrometry reporter tag.

Delaroche D, Aussedat B, Aubry S, Chassaing G, Burlina F, Clodic G, Bolbach G, Lavielle S, Sagan S.

Anal Chem. 2007 Mar 1;79(5):1932-8. Epub 2007 Jan 30.

PMID:
17260976
39.

High affinity Grb2-SH3 domain ligand incorporating Cbeta-substituted prolines in a Sos-derived decapeptide.

Jacquot Y, Broutin I, Miclet E, Nicaise M, Lequin O, Goasdoué N, Joss C, Karoyan P, Desmadril M, Ducruix A, Lavielle S.

Bioorg Med Chem. 2007 Feb 1;15(3):1439-47. Epub 2006 Nov 6.

PMID:
17113302
40.

The two NK-1 binding sites correspond to distinct, independent, and non-interconvertible receptor conformational states as confirmed by plasmon-waveguide resonance spectroscopy.

Alves ID, Delaroche D, Mouillac B, Salamon Z, Tollin G, Hruby VJ, Lavielle S, Sagan S.

Biochemistry. 2006 Apr 25;45(16):5309-18.

42.

Revisited and large-scale synthesis and purification of the mutated and wild type neu/erbB-2 membrane-spanning segment.

Khemtémourian L, Lavielle S, Bathany K, Schmitter JM, Dufourc EJ.

J Pept Sci. 2006 May;12(5):361-8.

PMID:
16285025
43.

Conformational analysis of the C-terminal Gly-Leu-Met-NH2 tripeptide of substance P bound to the NK-1 receptor.

Sagan S, Quancard J, Lequin O, Karoyan P, Chassaing G, Lavielle S.

Chem Biol. 2005 May;12(5):555-65.

44.

Chiral recognition and separation of beta2-amino acids using non-covalently molecularly imprinted polymers.

Shim YH, Yilmaz E, Lavielle S, Haupt K.

Analyst. 2004 Dec;129(12):1211-5. Epub 2004 Oct 13.

PMID:
15565220
45.

N- and Calpha-methylation in biologically active peptides: synthesis, structural and functional aspects.

Sagan S, Karoyan P, Lequin O, Chassaing G, Lavielle S.

Curr Med Chem. 2004 Nov;11(21):2799-822. Review.

PMID:
15544477
46.

Asymmetric synthesis of 3-substituted proline chimeras bearing polar side chains of proteinogenic amino acids.

Quancard J, Labonne A, Jacquot Y, Chassaing G, Lavielle S, Karoyan P.

J Org Chem. 2004 Nov 12;69(23):7940-8.

PMID:
15527274
47.

Incorporation of vinylogous scaffolds in the C-terminal tripeptide of substance P.

Claudel S, Tasseau O, Sagan S, Grison C, Coutrot P, Lavielle S.

J Pept Res. 2004 Nov;64(5):186-93.

PMID:
15485556
48.

Relative DNA binding affinity of helix 3 homeodomain analogues, major groove binders, can be rapidly screened by displacement of prebound ethidium bromide. A comparative study.

Shim YH, Arimondo PB, Laigle A, Garbesi A, Lavielle S.

Org Biomol Chem. 2004 Mar 21;2(6):915-21. Epub 2004 Feb 12.

PMID:
15007422
49.
50.

Characterization of the bioactive conformation of the C-terminal tripeptide Gly-Leu-Met-NH2 of substance P using [3-prolinoleucine10]SP analogues.

Quancard J, Karoyan P, Sagan S, Convert O, Lavielle S, Chassaing G, Lequin O.

Eur J Biochem. 2003 Jul;270(13):2869-78.

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