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Items: 8


Modulation of PICALM Levels Perturbs Cellular Cholesterol Homeostasis.

Mercer JL, Argus JP, Crabtree DM, Keenan MM, Wilks MQ, Chi JT, Bensinger SJ, Lavau CP, Wechsler DS.

PLoS One. 2015 Jun 15;10(6):e0129776. doi: 10.1371/journal.pone.0129776. eCollection 2015.


PICALM modulates autophagy activity and tau accumulation.

Moreau K, Fleming A, Imarisio S, Lopez Ramirez A, Mercer JL, Jimenez-Sanchez M, Bento CF, Puri C, Zavodszky E, Siddiqi F, Lavau CP, Betton M, O'Kane CJ, Wechsler DS, Rubinsztein DC.

Nat Commun. 2014 Sep 22;5:4998. doi: 10.1038/ncomms5998.


Effects of iron depletion on CALM-AF10 leukemias.

Heath JL, Weiss JM, Lavau CP, Wechsler DS.

Exp Hematol. 2014 Dec;42(12):1022-1030.e1. doi: 10.1016/j.exphem.2014.08.004. Epub 2014 Sep 3.


A critical role for CRM1 in regulating HOXA gene transcription in CALM-AF10 leukemias.

Conway AE, Haldeman JM, Wechsler DS, Lavau CP.

Leukemia. 2015 Feb;29(2):423-32. doi: 10.1038/leu.2014.221. Epub 2014 Jul 16.


Iron deprivation in cancer--potential therapeutic implications.

Heath JL, Weiss JM, Lavau CP, Wechsler DS.

Nutrients. 2013 Jul 24;5(8):2836-59. doi: 10.3390/nu5082836. Review.


A CALM-derived nuclear export signal is essential for CALM-AF10-mediated leukemogenesis.

Conway AE, Scotland PB, Lavau CP, Wechsler DS.

Blood. 2013 Jun 6;121(23):4758-68. doi: 10.1182/blood-2012-06-435792. Epub 2013 Mar 13.


The PICALM protein plays a key role in iron homeostasis and cell proliferation.

Scotland PB, Heath JL, Conway AE, Porter NB, Armstrong MB, Walker JA, Klebig ML, Lavau CP, Wechsler DS.

PLoS One. 2012;7(8):e44252. doi: 10.1371/journal.pone.0044252. Epub 2012 Aug 30.


Abl family kinases modulate T cell-mediated inflammation and chemokine-induced migration through the adaptor HEF1 and the GTPase Rap1.

Gu JJ, Lavau CP, Pugacheva E, Soderblom EJ, Moseley MA, Pendergast AM.

Sci Signal. 2012 Jul 17;5(233):ra51. doi: 10.1126/scisignal.2002632.

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