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Items: 1 to 50 of 62

1.

Modulating the cardiotoxic behaviour of immunoglobulin light chain dimers through point mutations.

Maritan M, Ambrosetti A, Oberti L, Barbiroli A, Diomede L, Romeo M, Lavatelli F, Sormanni P, Palladini G, Bolognesi M, Merlini G, Ricagno S.

Amyloid. 2019;26(sup1):105-106. doi: 10.1080/13506129.2019.1583185. No abstract available.

PMID:
31343361
2.

The concurrency of several biophysical traits links immunoglobulin light chains with toxicity in AL amyloidosis.

Oberti L, Maritan M, Rognoni P, Barbiroli A, Lavatelli F, Russo R, Palladini G, Bolognesi M, Merlini G, Ricagno S.

Amyloid. 2019;26(sup1):107-108. doi: 10.1080/13506129.2019.1583187. No abstract available.

PMID:
31343357
3.

Simple, reliable detection of amyloid in fat aspirates using the fluorescent dye FSB: prospective study in 206 patients.

Tasaki M, Milani P, Foli A, Verga L, Obici L, Basset M, Bozzola M, Ferraro G, Nuvolone M, Morbini P, Capello G, Ueda M, Obayashi K, Paulli M, Ando Y, Merlini G, Palladini G, Lavatelli F.

Blood. 2019 Jul 18;134(3):320-323. doi: 10.1182/blood.2019000420. Epub 2019 Jun 6. No abstract available.

PMID:
31171502
4.

Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain AL amyloidosis patient.

Swuec P, Lavatelli F, Tasaki M, Paissoni C, Rognoni P, Maritan M, Brambilla F, Milani P, Mauri P, Camilloni C, Palladini G, Merlini G, Ricagno S, Bolognesi M.

Nat Commun. 2019 Mar 20;10(1):1269. doi: 10.1038/s41467-019-09133-w.

5.

Zebrafish model of amyloid light chain cardiotoxicity: regeneration versus degeneration.

Mishra S, Joshi S, Ward JE, Buys EP, Mishra D, Mishra D, Morgado I, Fisch S, Lavatelli F, Merlini G, Dorbala S, MacRae CA, Liao R.

Am J Physiol Heart Circ Physiol. 2019 May 1;316(5):H1158-H1166. doi: 10.1152/ajpheart.00788.2018. Epub 2019 Mar 15.

PMID:
30875258
6.

ATR-FTIR Spectroscopy Supported by Multivariate Analysis for the Characterization of Adipose Tissue Aspirates from Patients Affected by Systemic Amyloidosis.

Ami D, Mereghetti P, Foli A, Tasaki M, Milani P, Nuvolone M, Palladini G, Merlini G, Lavatelli F, Natalello A.

Anal Chem. 2019 Feb 19;91(4):2894-2900. doi: 10.1021/acs.analchem.8b05008. Epub 2019 Feb 4.

PMID:
30676723
7.

Proteomics with Mass Spectrometry Imaging: Beyond Amyloid Typing.

Lavatelli F, Merlini G.

Proteomics. 2018 Apr;18(7):e1700353. doi: 10.1002/pmic.201700353. Epub 2018 Mar 8.

PMID:
29389069
8.

Concurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity.

Oberti L, Rognoni P, Barbiroli A, Lavatelli F, Russo R, Maritan M, Palladini G, Bolognesi M, Merlini G, Ricagno S.

Sci Rep. 2017 Dec 1;7(1):16809. doi: 10.1038/s41598-017-16953-7.

9.

Proteotoxicity in cardiac amyloidosis: amyloidogenic light chains affect the levels of intracellular proteins in human heart cells.

Imperlini E, Gnecchi M, Rognoni P, Sabidò E, Ciuffreda MC, Palladini G, Espadas G, Mancuso FM, Bozzola M, Malpasso G, Valentini V, Palladini G, Orrù S, Ferraro G, Milani P, Perlini S, Salvatore F, Merlini G, Lavatelli F.

Sci Rep. 2017 Nov 15;7(1):15661. doi: 10.1038/s41598-017-15424-3.

10.

How do we improve treatments for patients with amyloidosis using proteomics?

Lavatelli F, Merlini G.

Expert Rev Proteomics. 2017 Jul;14(7):561-563. doi: 10.1080/14789450.2017.1331737. Epub 2017 May 23. Review. No abstract available.

PMID:
28524784
11.

Patients with AL amyloidosis and low free light-chain burden have distinct clinical features and outcome.

Milani P, Basset M, Russo F, Foli A, Lavatelli F, Nuvolone M, Ferraro G, Palladini G, Merlini G.

Amyloid. 2017 Mar;24(sup1):64-65. doi: 10.1080/13506129.2017.1293517. No abstract available.

PMID:
28434343
12.

Patterns of relapse after upfront bortezomib therapy in AL amyloidosis.

Basset M, Milani P, Russo F, Lavatelli F, Nuvolone M, Foli A, Perlini S, Palladini G, Merlini G.

Amyloid. 2017 Mar;24(sup1):60-61. doi: 10.1080/13506129.2017.1292901. No abstract available.

PMID:
28434342
13.

Urinary albumin to creatinine ratio in diagnosis and risk stratification of renal AL amyloidosis.

Palladini G, Milani P, Basset M, Russo F, Lavatelli F, Nuvolone M, Ferraro G, Bozzola M, Foli A, Merlini G.

Amyloid. 2017 Mar;24(sup1):68-69. doi: 10.1080/13506129.2017.1293644. No abstract available.

PMID:
28434326
14.

Identification and quantification of urinary monoclonal proteins by capillary electrophoresis in AL amyloidosis.

Russo F, Valentini V, Basset M, Bosoni T, Milani P, Ferraro G, Pirolini L, Foli A, Lavatelli F, Belvisi F, Consogno G, Nuvolone M, Li Bergolis F, Bozzola M, Albertini R, Palladini G, Merlini G.

Amyloid. 2017 Mar;24(sup1):66-67. doi: 10.1080/13506129.2017.1293643. No abstract available.

PMID:
28434323
15.

Severity and reversibility of cardiac dysfunction and residual concentration of amyloidogenic light chain predict overall survival of patients with AL amyloidosis who attain complete response.

Palladini G, Milani P, Basset M, Russo F, Lavatelli F, Nuvolone M, Ferraro G, Bozzola M, Foli A, Perlini S, Merlini G.

Amyloid. 2017 Mar;24(sup1):54-55. doi: 10.1080/13506129.2017.1289916. No abstract available.

PMID:
28434293
16.

Prognostication of survival and progression to dialysis in AA amyloidosis.

Palladini G, Riva E, Basset M, Russo F, Milani P, Pasquinucci E, Foli A, Lavatelli F, Nuvolone M, Casarini S, Obici L, Merlini G.

Amyloid. 2017 Mar;24(sup1):136-137. doi: 10.1080/13506129.2017.1289917. No abstract available.

PMID:
28434292
17.

Regulated expression of amyloidogenic immunoglobulin light chains in mice.

Nuvolone M, Sorce S, Pelczar P, Rushing E, Lavatelli F, Rognoni P, Valentini V, Palladini G, Merlini G, Aguzzi A.

Amyloid. 2017 Mar;24(sup1):52-53. doi: 10.1080/13506129.2017.1289914. No abstract available.

PMID:
28434289
18.

Circulating free light chain measurement in the diagnosis, prognostic assessment and evaluation of response of AL amyloidosis: comparison of Freelite and N latex FLC assays.

Palladini G, Jaccard A, Milani P, Lavergne D, Foli A, Bender S, Lavatelli F, Bosoni T, Valentini V, Pirolini L, Ferraro G, Basset M, Russo F, Nuvolone M, Albertini R, Cogne M, Merlini G.

Clin Chem Lab Med. 2017 Oct 26;55(11):1734-1743. doi: 10.1515/cclm-2016-1024.

PMID:
28343171
19.

Advances in proteomic study of cardiac amyloidosis: progress and potential.

Lavatelli F, Merlini G.

Expert Rev Proteomics. 2016 Nov;13(11):1017-1027. doi: 10.1080/14789450.2016.1242417. Epub 2016 Oct 19.

PMID:
27678147
20.

In situ characterization of protein aggregates in human tissues affected by light chain amyloidosis: a FTIR microspectroscopy study.

Ami D, Lavatelli F, Rognoni P, Palladini G, Raimondi S, Giorgetti S, Monti L, Doglia SM, Natalello A, Merlini G.

Sci Rep. 2016 Jul 4;6:29096. doi: 10.1038/srep29096.

21.

The impact of renal function on the clinical performance of FLC measurement in AL amyloidosis.

Palladini G, Milani P, Foli A, Basset M, Russo F, Bosoni T, Pirolini L, Valentini V, Ferraro G, Lavatelli F, Barassi A, Albertini R, Merlini G.

Clin Chem Lab Med. 2016 Jun 1;54(6):939-45. doi: 10.1515/cclm-2015-0985.

PMID:
26943606
22.

Systemic amyloidoses and proteomics: The state of the art.

Lavatelli F, di Fonzo A, Palladini G, Merlini G.

EuPA Open Proteom. 2016 Feb 23;11:4-10. doi: 10.1016/j.euprot.2016.02.003. eCollection 2016 Jun.

23.

Nutritional counseling improves quality of life and preserves body weight in systemic immunoglobulin light-chain (AL) amyloidosis.

Caccialanza R, Palladini G, Cereda E, Bonardi C, Milani P, Cameletti B, Quarleri L, Cappello S, Foli A, Lavatelli F, Klersy C, Merlini G.

Nutrition. 2015 Oct;31(10):1228-34. doi: 10.1016/j.nut.2015.04.011. Epub 2015 May 11.

PMID:
26250487
24.

Novel mitochondrial protein interactors of immunoglobulin light chains causing heart amyloidosis.

Lavatelli F, Imperlini E, Orrù S, Rognoni P, Sarnataro D, Palladini G, Malpasso G, Soriano ME, Di Fonzo A, Valentini V, Gnecchi M, Perlini S, Salvatore F, Merlini G.

FASEB J. 2015 Nov;29(11):4614-28. doi: 10.1096/fj.15-272179. Epub 2015 Jul 28.

PMID:
26220173
25.

A practical approach to the diagnosis of systemic amyloidoses.

Fernández de Larrea C, Verga L, Morbini P, Klersy C, Lavatelli F, Foli A, Obici L, Milani P, Capello GL, Paulli M, Palladini G, Merlini G.

Blood. 2015 Apr 2;125(14):2239-44. doi: 10.1182/blood-2014-11-609883. Epub 2015 Jan 30.

PMID:
25636337
26.

Melphalan and dexamethasone with or without bortezomib in newly diagnosed AL amyloidosis: a matched case-control study on 174 patients.

Palladini G, Milani P, Foli A, Vidus Rosin M, Basset M, Lavatelli F, Nuvolone M, Obici L, Perlini S, Merlini G.

Leukemia. 2014 Dec;28(12):2311-6. doi: 10.1038/leu.2014.227. Epub 2014 Jul 25.

PMID:
25059496
27.

Investigating heart-specific toxicity of amyloidogenic immunoglobulin light chains: A lesson from C. elegans.

Diomede L, Rognoni P, Lavatelli F, Romeo M, di Fonzo A, Foray C, Fiordaliso F, Palladini G, Valentini V, Perfetti V, Salmona M, Merlini G.

Worm. 2014 Oct 30;3(3):e965590. doi: 10.4161/21624046.2014.965590. eCollection 2014 Jul-Sep.

28.

Biochemical markers in early diagnosis and management of systemic amyloidoses.

Lavatelli F, Albertini R, Di Fonzo A, Palladini G, Merlini G.

Clin Chem Lab Med. 2014 Nov;52(11):1517-31. doi: 10.1515/cclm-2014-0235. Review.

29.

A Caenorhabditis elegans-based assay recognizes immunoglobulin light chains causing heart amyloidosis.

Diomede L, Rognoni P, Lavatelli F, Romeo M, del Favero E, Cantù L, Ghibaudi E, di Fonzo A, Corbelli A, Fiordaliso F, Palladini G, Valentini V, Perfetti V, Salmona M, Merlini G.

Blood. 2014 Jun 5;123(23):3543-52. doi: 10.1182/blood-2013-10-525634. Epub 2014 Mar 24.

30.

Oral melphalan and dexamethasone grants extended survival with minimal toxicity in AL amyloidosis: long-term results of a risk-adapted approach.

Palladini G, Milani P, Foli A, Obici L, Lavatelli F, Nuvolone M, Caccialanza R, Perlini S, Merlini G.

Haematologica. 2014 Apr;99(4):743-50. doi: 10.3324/haematol.2013.095463. Epub 2013 Nov 8.

31.

A strategy for synthesis of pathogenic human immunoglobulin free light chains in E. coli.

Rognoni P, Lavatelli F, Casarini S, Palladini G, Verga L, Pedrazzoli P, Valentini G, Merlini G, Perfetti V.

PLoS One. 2013 Sep 27;8(9):e76022. doi: 10.1371/journal.pone.0076022. eCollection 2013.

32.

Shotgun protein profile of human adipose tissue and its changes in relation to systemic amyloidoses.

Brambilla F, Lavatelli F, Di Silvestre D, Valentini V, Palladini G, Merlini G, Mauri P.

J Proteome Res. 2013 Dec 6;12(12):5642-55. doi: 10.1021/pr400583h. Epub 2013 Oct 21.

PMID:
24083510
33.

Malnutrition at diagnosis predicts mortality in patients with systemic immunoglobulin light-chain amyloidosis independently of cardiac stage and response to treatment.

Caccialanza R, Palladini G, Klersy C, Cereda E, Bonardi C, Cameletti B, Quarleri L, Montagna E, Foli A, Milani P, Lavatelli F, Marena C, Merlini G.

JPEN J Parenter Enteral Nutr. 2014 Sep;38(7):891-4. doi: 10.1177/0148607113501328. Epub 2013 Sep 26.

PMID:
24072737
34.

Stanniocalcin1 is a key mediator of amyloidogenic light chain induced cardiotoxicity.

Guan J, Mishra S, Shi J, Plovie E, Qiu Y, Cao X, Gianni D, Jiang B, Del Monte F, Connors LH, Seldin DC, Lavatelli F, Rognoni P, Palladini G, Merlini G, Falk RH, Semigran MJ, Dec GW Jr, Macrae CA, Liao R.

Basic Res Cardiol. 2013 Sep;108(5):378. doi: 10.1007/s00395-013-0378-5. Epub 2013 Aug 28.

35.

Amyloid fibrils containing fragmented ATTR may be the standard fibril composition in ATTR amyloidosis.

Ihse E, Rapezzi C, Merlini G, Benson MD, Ando Y, Suhr OB, Ikeda S, Lavatelli F, Obici L, Quarta CC, Leone O, Jono H, Ueda M, Lorenzini M, Liepnieks J, Ohshima T, Tasaki M, Yamashita T, Westermark P.

Amyloid. 2013 Sep;20(3):142-50. doi: 10.3109/13506129.2013.797890. Epub 2013 May 28.

PMID:
23713495
36.

Clinical proteomics for diagnosis and typing of systemic amyloidoses.

Brambilla F, Lavatelli F, Merlini G, Mauri P.

Proteomics Clin Appl. 2013 Jan;7(1-2):136-43. doi: 10.1002/prca.201200097. Review.

PMID:
23184874
37.

A phase II trial of cyclophosphamide, lenalidomide and dexamethasone in previously treated patients with AL amyloidosis.

Palladini G, Russo P, Milani P, Foli A, Lavatelli F, Nuvolone M, Perlini S, Merlini G.

Haematologica. 2013 Mar;98(3):433-6. doi: 10.3324/haematol.2012.073593. Epub 2012 Sep 14.

38.

Changes in tissue proteome associated with ATTR amyloidosis: insights into pathogenesis.

Brambilla F, Lavatelli F, Valentini V, Di Silvestre D, Obici L, Mauri P, Merlini G.

Amyloid. 2012 Jun;19 Suppl 1:11-3. doi: 10.3109/13506129.2012.674989. Epub 2012 May 2.

PMID:
22551153
39.

Best use of cardiac biomarkers in patients with AL amyloidosis and renal failure.

Palladini G, Foli A, Milani P, Russo P, Albertini R, Lavatelli F, Obici L, Perlini S, Moratti R, Merlini G.

Am J Hematol. 2012 May;87(5):465-71. doi: 10.1002/ajh.23141. Epub 2012 Mar 3.

40.

Proteomic typing of amyloid deposits in systemic amyloidoses.

Lavatelli F, Vrana JA.

Amyloid. 2011 Dec;18(4):177-82. doi: 10.3109/13506129.2011.630762. Review.

PMID:
22080761
41.

Midregional proadrenomedullin (MR-proADM) is a powerful predictor of early death in AL amyloidosis.

Palladini G, Barassi A, Perlini S, Milani P, Foli A, Russo P, Albertini R, Obici L, Lavatelli F, Sarais G, Casarini S, Moratti R, Melzi d'Eril GV, Merlini G.

Amyloid. 2011 Dec;18(4):216-21. doi: 10.3109/13506129.2011.627069. Epub 2011 Nov 9.

PMID:
22070520
42.

Reliable typing of systemic amyloidoses through proteomic analysis of subcutaneous adipose tissue.

Brambilla F, Lavatelli F, Di Silvestre D, Valentini V, Rossi R, Palladini G, Obici L, Verga L, Mauri P, Merlini G.

Blood. 2012 Feb 23;119(8):1844-7. doi: 10.1182/blood-2011-07-365510. Epub 2011 Sep 13.

PMID:
21917755
43.

AMICA: an electronic patient record specifically designed for an amyloidosis network.

Ferrari R, Caffi E, Quaglini S, Stefanelli M, Russo P, Palladini G, Lavatelli F, Merlini G.

Amyloid. 2011 Jun;18 Suppl 1:236-8. doi: 10.3109/13506129.2011.574354089. No abstract available. Erratum in: Amyloid. 2011 Jun;18 Suppl 1:238.

PMID:
21838501
44.

A workflow management system for the biological samples exchange within the amyloidosis network.

Panzarasa S, Quaglini S, Ferrari R, Stefanelli M, Foli A, Palladini G, Russo P, Lavatelli F.

Amyloid. 2011 Jun;18 Suppl 1:233-5. doi: 10.3109/13506129.2011.574354088. No abstract available. Erratum in: Amyloid. 2011 Jun;18 Suppl 1:235.

PMID:
21838500
45.

Functional correlates of N-terminal natriuretic peptide type B (NT-proBNP) response to therapy in cardiac light chain (AL) amyloidosis.

Perlini S, Musca F, Salinaro F, Fracchioni I, Palladini G, Obici L, Albertini R, Moratti R, Lavatelli F, Palladini G, Rapezzi C, Merlini G.

Amyloid. 2011 Jun;18 Suppl 1:96-7. doi: 10.3109/13506129.2011.574354035. No abstract available. Erratum in: Amyloid. 2011 Jun;18 Suppl 1:97.

PMID:
21838447
46.

Mass spectrometry-based proteomics as a diagnostic tool when immunoelectron microscopy fails in typing amyloid deposits.

Lavatelli F, Valentini V, Palladini G, Verga L, Russo P, Foli A, Obici L, Sarais G, Perfetti V, Casarini S, Merlini G.

Amyloid. 2011 Jun;18 Suppl 1:64-6. doi: 10.3109/13506129.2011.574354023. No abstract available. Erratum in: Amyloid. 2011 Jun;18 Suppl 1:66.

PMID:
21838435
47.

Proteomic characterization of amyloid deposits in transthyretin amyloidosis associated with various mutations.

Valentini V, Lavatelli F, Obici L, Donadei S, Perlini S, Palladini G, Merlini G.

Amyloid. 2011 Jun;18 Suppl 1:61-3. doi: 10.3109/13506129.2011.574354022. No abstract available. Erratum in: Amyloid. 2011 Jun;18 Suppl 1:63.

PMID:
21838434
48.

Nutritional status independently affects quality of life of patients with systemic immunoglobulin light-chain (AL) amyloidosis.

Caccialanza R, Palladini G, Klersy C, Cereda E, Bonardi C, Cameletti B, Montagna E, Russo P, Foli A, Milani P, Lavatelli F, Merlini G.

Ann Hematol. 2012 Mar;91(3):399-406. doi: 10.1007/s00277-011-1309-x. Epub 2011 Aug 9.

PMID:
21826471
49.

Salvage therapy with lenalidomide and dexamethasone in patients with advanced AL amyloidosis refractory to melphalan, bortezomib, and thalidomide.

Palladini G, Russo P, Foli A, Milani P, Lavatelli F, Obici L, Nuvolone M, Brugnatelli S, Invernizzi R, Merlini G.

Ann Hematol. 2012 Jan;91(1):89-92. doi: 10.1007/s00277-011-1244-x. Epub 2011 Apr 30.

PMID:
21533608
50.

Treatment of IgM-associated AL amyloidosis with the combination of rituximab, bortezomib, and dexamethasone.

Palladini G, Foli A, Russo P, Milani P, Obici L, Lavatelli F, Merlini G.

Clin Lymphoma Myeloma Leuk. 2011 Feb;11(1):143-5. doi: 10.3816/CLML.2011.n.033.

PMID:
21454217

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