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Items: 26


Proteomic analyses reveal misregulation of LIN28 expression and delayed timing of glial differentiation in human iPS cells with MECP2 loss-of-function.

Kim JJ, Savas JN, Miller MT, Hu X, Carromeu C, Lavallée-Adam M, Freitas BCG, Muotri AR, Yates JR 3rd, Ghosh A.

PLoS One. 2019 Feb 21;14(2):e0212553. doi: 10.1371/journal.pone.0212553. eCollection 2019.


A complex of C9ORF72 and p62 uses arginine methylation to eliminate stress granules by autophagy.

Chitiprolu M, Jagow C, Tremblay V, Bondy-Chorney E, Paris G, Savard A, Palidwor G, Barry FA, Zinman L, Keith J, Rogaeva E, Robertson J, Lavallée-Adam M, Woulfe J, Couture JF, Côté J, Gibbings D.

Nat Commun. 2018 Jul 18;9(1):2794. doi: 10.1038/s41467-018-05273-7.


Increased proteomic complexity in Drosophila hybrids during development.

Bamberger C, Martínez-Bartolomé S, Montgomery M, Lavallée-Adam M, Yates JR 3rd.

Sci Adv. 2018 Feb 7;4(2):eaao3424. doi: 10.1126/sciadv.aao3424. eCollection 2018 Feb.


Amyloid Accumulation Drives Proteome-wide Alterations in Mouse Models of Alzheimer's Disease-like Pathology.

Savas JN, Wang YZ, DeNardo LA, Martinez-Bartolome S, McClatchy DB, Hark TJ, Shanks NF, Cozzolino KA, Lavallée-Adam M, Smukowski SN, Park SK, Kelly JW, Koo EH, Nakagawa T, Masliah E, Ghosh A, Yates JR 3rd.

Cell Rep. 2017 Nov 28;21(9):2614-2627. doi: 10.1016/j.celrep.2017.11.009.


High infestation levels of Schizotetranychus oryzae severely affects rice metabolism.

Blasi ÉAR, Buffon G, Rativa AGS, Lopes MCB, Berger M, Santi L, Lavallée-Adam M, Yates JR 3rd, Schwambach J, Beys-da-Silva WO, Sperotto RA.

J Plant Physiol. 2017 Dec;219:100-111. doi: 10.1016/j.jplph.2017.10.005. Epub 2017 Oct 28.


Proteomic and Metaproteomic Approaches to Understand Host-Microbe Interactions.

Starr AE, Deeke SA, Li L, Zhang X, Daoud R, Ryan J, Ning Z, Cheng K, Nguyen LVH, Abou-Samra E, Lavallée-Adam M, Figeys D.

Anal Chem. 2018 Jan 2;90(1):86-109. doi: 10.1021/acs.analchem.7b04340. Epub 2017 Nov 9. Review. No abstract available.


Functional 5' UTR motif discovery with LESMoN: Local Enrichment of Sequence Motifs in biological Networks.

Lavallée-Adam M, Cloutier P, Coulombe B, Blanchette M.

Nucleic Acids Res. 2017 Oct 13;45(18):10415-10427. doi: 10.1093/nar/gkx751.


Quantitative Analysis of the Proteome Response to the Histone Deacetylase Inhibitor (HDACi) Vorinostat in Niemann-Pick Type C1 disease.

Subramanian K, Rauniyar N, Lavalleé-Adam M, Yates JR 3rd, Balch WE.

Mol Cell Proteomics. 2017 Nov;16(11):1938-1957. doi: 10.1074/mcp.M116.064949. Epub 2017 Aug 31.


Using PSEA-Quant for Protein Set Enrichment Analysis of Quantitative Mass Spectrometry-Based Proteomics.

Lavallée-Adam M, Yates JR 3rd.

Curr Protoc Bioinformatics. 2016 Mar 24;53:13.28.1-16. doi: 10.1002/0471250953.bi1328s53.


Physiological and Molecular Alterations Promoted by Schizotetranychus oryzae Mite Infestation in Rice Leaves.

Buffon G, Blasi ÉA, Adamski JM, Ferla NJ, Berger M, Santi L, Lavallée-Adam M, Yates JR 3rd, Beys-da-Silva WO, Sperotto RA.

J Proteome Res. 2016 Feb 5;15(2):431-46. doi: 10.1021/acs.jproteome.5b00729. Epub 2015 Dec 30.


∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.

Pankow S, Bamberger C, Calzolari D, Martínez-Bartolomé S, Lavallée-Adam M, Balch WE, Yates JR 3rd.

Nature. 2015 Dec 24;528(7583):510-6. doi: 10.1038/nature15729. Epub 2015 Nov 30.


The Sorting Receptor SorCS1 Regulates Trafficking of Neurexin and AMPA Receptors.

Savas JN, Ribeiro LF, Wierda KD, Wright R, DeNardo-Wilke LA, Rice HC, Chamma I, Wang YZ, Zemla R, Lavallée-Adam M, Vennekens KM, O'Sullivan ML, Antonios JK, Hall EA, Thoumine O, Attie AD, Yates JR 3rd, Ghosh A, de Wit J.

Neuron. 2015 Aug 19;87(4):764-80. doi: 10.1016/j.neuron.2015.08.007.


Curation of the Mammalian Palmitoylome Indicates a Pivotal Role for Palmitoylation in Diseases and Disorders of the Nervous System and Cancers.

Sanders SS, Martin DD, Butland SL, Lavallée-Adam M, Calzolari D, Kay C, Yates JR 3rd, Hayden MR.

PLoS Comput Biol. 2015 Aug 14;11(8):e1004405. doi: 10.1371/journal.pcbi.1004405. eCollection 2015 Aug.


Recessive mutations in POLR1C cause a leukodystrophy by impairing biogenesis of RNA polymerase III.

Thiffault I, Wolf NI, Forget D, Guerrero K, Tran LT, Choquet K, Lavallée-Adam M, Poitras C, Brais B, Yoon G, Sztriha L, Webster RI, Timmann D, van de Warrenburg BP, Seeger J, Zimmermann A, Máté A, Goizet C, Fung E, van der Knaap MS, Fribourg S, Vanderver A, Simons C, Taft RJ, Yates JR 3rd, Coulombe B, Bernard G.

Nat Commun. 2015 Jul 7;6:7623. doi: 10.1038/ncomms8623.


From raw data to biological discoveries: a computational analysis pipeline for mass spectrometry-based proteomics.

Lavallée-Adam M, Park SK, Martínez-Bartolomé S, He L, Yates JR 3rd.

J Am Soc Mass Spectrom. 2015 Nov;26(11):1820-6. doi: 10.1007/s13361-015-1161-7. Epub 2015 May 22.


Quantitative Proteomics of Human Fibroblasts with I1061T Mutation in Niemann-Pick C1 (NPC1) Protein Provides Insights into the Disease Pathogenesis.

Rauniyar N, Subramanian K, Lavallée-Adam M, Martínez-Bartolomé S, Balch WE, Yates JR 3rd.

Mol Cell Proteomics. 2015 Jul;14(7):1734-49. doi: 10.1074/mcp.M114.045609. Epub 2015 Apr 14.


Sheathless capillary electrophoresis-tandem mass spectrometry for top-down characterization of Pyrococcus furiosus proteins on a proteome scale.

Han X, Wang Y, Aslanian A, Bern M, Lavallée-Adam M, Yates JR 3rd.

Anal Chem. 2014 Nov 18;86(22):11006-12. doi: 10.1021/ac503439n. Epub 2014 Oct 30.


PSEA-Quant: a protein set enrichment analysis on label-free and label-based protein quantification data.

Lavallée-Adam M, Rauniyar N, McClatchy DB, Yates JR 3rd.

J Proteome Res. 2014 Dec 5;13(12):5496-509. doi: 10.1021/pr500473n. Epub 2014 Oct 16.


Methylation of the DNA/RNA-binding protein Kin17 by METTL22 affects its association with chromatin.

Cloutier P, Lavallée-Adam M, Faubert D, Blanchette M, Coulombe B.

J Proteomics. 2014 Apr 4;100:115-24. doi: 10.1016/j.jprot.2013.10.008. Epub 2013 Oct 16.


Nuclear import of RNA polymerase II is coupled with nucleocytoplasmic shuttling of the RNA polymerase II-associated protein 2.

Forget D, Lacombe AA, Cloutier P, Lavallée-Adam M, Blanchette M, Coulombe B.

Nucleic Acids Res. 2013 Aug;41(14):6881-91. doi: 10.1093/nar/gkt455. Epub 2013 May 30.


A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity.

Cloutier P, Lavallée-Adam M, Faubert D, Blanchette M, Coulombe B.

PLoS Genet. 2013;9(1):e1003210. doi: 10.1371/journal.pgen.1003210. Epub 2013 Jan 17.


Discovery of cell compartment specific protein-protein interactions using affinity purification combined with tandem mass spectrometry.

Lavallée-Adam M, Rousseau J, Domecq C, Bouchard A, Forget D, Faubert D, Blanchette M, Coulombe B.

J Proteome Res. 2013 Jan 4;12(1):272-81. doi: 10.1021/pr300778b. Epub 2012 Dec 4.


Modeling contaminants in AP-MS/MS experiments.

Lavallée-Adam M, Cloutier P, Coulombe B, Blanchette M.

J Proteome Res. 2011 Feb 4;10(2):886-95. doi: 10.1021/pr100795z. Epub 2010 Dec 31.


The protein interaction network of the human transcription machinery reveals a role for the conserved GTPase RPAP4/GPN1 and microtubule assembly in nuclear import and biogenesis of RNA polymerase II.

Forget D, Lacombe AA, Cloutier P, Al-Khoury R, Bouchard A, Lavallée-Adam M, Faubert D, Jeronimo C, Blanchette M, Coulombe B.

Mol Cell Proteomics. 2010 Dec;9(12):2827-39. doi: 10.1074/mcp.M110.003616. Epub 2010 Sep 20.


Detection of locally over-represented GO terms in protein-protein interaction networks.

Lavallée-Adam M, Coulombe B, Blanchette M.

J Comput Biol. 2010 Mar;17(3):443-57. doi: 10.1089/cmb.2009.0165.


High-resolution mapping of the protein interaction network for the human transcription machinery and affinity purification of RNA polymerase II-associated complexes.

Cloutier P, Al-Khoury R, Lavallée-Adam M, Faubert D, Jiang H, Poitras C, Bouchard A, Forget D, Blanchette M, Coulombe B.

Methods. 2009 Aug;48(4):381-6. doi: 10.1016/j.ymeth.2009.05.005. Epub 2009 May 18.

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