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Items: 31


Evaluation of Holistic Treatment for ALS Reveals Possible Mechanism and Therapeutic Potential.

Lavado A, Guo X, Smith AS, Akanda N, Martin C, Cai Y, Elbrecht D, Tran M, Bryant JP, Colon A, Long CJ, Lambert S, Morgan D, Hickman JJ.

Int J Pharm Pharm Res. 2017 Dec;11(1):348-374. Epub 2017 Dec 30.


Modulatory Effect of Guinep (Melicoccus bijugatus Jacq) Fruit Pulp Extract on Isoproterenol-Induced Myocardial Damage in Rats. Identification of Major Metabolites Using High Resolution UHPLC Q-Orbitrap Mass Spectrometry.

Nwokocha CR, Warren I, Palacios J, Simirgiotis M, Nwokocha M, Harrison S, Thompson R, Paredes A, Bórquez J, Lavado A, Cifuentes F.

Molecules. 2019 Jan 10;24(2). pii: E235. doi: 10.3390/molecules24020235.


The Hippo Pathway Prevents YAP/TAZ-Driven Hypertranscription and Controls Neural Progenitor Number.

Lavado A, Park JY, Paré J, Finkelstein D, Pan H, Xu B, Fan Y, Kumar RP, Neale G, Kwak YD, McKinnon PJ, Johnson RL, Cao X.

Dev Cell. 2018 Dec 3;47(5):576-591.e8. doi: 10.1016/j.devcel.2018.09.021. Epub 2018 Oct 25.


Investigation of the effect of hepatic metabolism on off-target cardiotoxicity in a multi-organ human-on-a-chip system.

Oleaga C, Riu A, Rothemund S, Lavado A, McAleer CW, Long CJ, Persaud K, Narasimhan NS, Tran M, Roles J, Carmona-Moran CA, Sasserath T, Elbrecht DH, Kumanchik L, Bridges LR, Martin C, Schnepper MT, Ekman G, Jackson M, Wang YI, Note R, Langer J, Teissier S, Hickman JJ.

Biomaterials. 2018 Nov;182:176-190. doi: 10.1016/j.biomaterials.2018.07.062. Epub 2018 Aug 4.


Stem cell derived phenotypic human neuromuscular junction model for dose response evaluation of therapeutics.

Santhanam N, Kumanchik L, Guo X, Sommerhage F, Cai Y, Jackson M, Martin C, Saad G, McAleer CW, Wang Y, Lavado A, Long CJ, Hickman JJ.

Biomaterials. 2018 Jun;166:64-78. doi: 10.1016/j.biomaterials.2018.02.047. Epub 2018 Feb 27.


An Eye Organoid Approach Identifies Six3 Suppression of R-spondin 2 as a Critical Step in Mouse Neuroretina Differentiation.

Takata N, Abbey D, Fiore L, Acosta S, Feng R, Gil HJ, Lavado A, Geng X, Interiano A, Neale G, Eiraku M, Sasai Y, Oliver G.

Cell Rep. 2017 Nov 7;21(6):1534-1549. doi: 10.1016/j.celrep.2017.10.041.


The autophagy-inducing kinases, ULK1 and ULK2, regulate axon guidance in the developing mouse forebrain via a noncanonical pathway.

Wang B, Iyengar R, Li-Harms X, Joo JH, Wright C, Lavado A, Horner L, Yang M, Guan JL, Frase S, Green DR, Cao X, Kundu M.

Autophagy. 2018;14(5):796-811. doi: 10.1080/15548627.2017.1386820. Epub 2017 Dec 24.


Mental health problems in male young offenders in custodial versus community based-programs: implications for juvenile justice interventions.

Rijo D, Brazão N, Barroso R, da Silva DR, Vagos P, Vieira A, Lavado A, Macedo AM.

Child Adolesc Psychiatry Ment Health. 2016 Nov 1;10:40. eCollection 2016.


Prox1 Regulates the Subtype-Specific Development of Caudal Ganglionic Eminence-Derived GABAergic Cortical Interneurons.

Miyoshi G, Young A, Petros T, Karayannis T, McKenzie Chang M, Lavado A, Iwano T, Nakajima M, Taniguchi H, Huang ZJ, Heintz N, Oliver G, Matsuzaki F, Machold RP, Fishell G.

J Neurosci. 2015 Sep 16;35(37):12869-89. doi: 10.1523/JNEUROSCI.1164-15.2015.


Controlled intracellular generation of reactive oxygen species in human mesenchymal stem cells using porphyrin conjugated nanoparticles.

Lavado AS, Chauhan VM, Zen AA, Giuntini F, Jones DR, Boyle RW, Beeby A, Chan WC, Aylott JW.

Nanoscale. 2015 Sep 14;7(34):14525-31. doi: 10.1039/c5nr00795j.


The tumor suppressor Nf2 regulates corpus callosum development by inhibiting the transcriptional coactivator Yap.

Lavado A, Ware M, Paré J, Cao X.

Development. 2014 Nov;141(21):4182-93. doi: 10.1242/dev.111260.


Jagged1 is necessary for postnatal and adult neurogenesis in the dentate gyrus.

Lavado A, Oliver G.

Dev Biol. 2014 Apr 1;388(1):11-21. doi: 10.1016/j.ydbio.2014.02.004. Epub 2014 Feb 13.


Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators.

Lavado A, He Y, Paré J, Neale G, Olson EN, Giovannini M, Cao X.

Development. 2013 Aug;140(16):3323-34. doi: 10.1242/dev.096537. Epub 2013 Jul 17.


Orthogonally bifunctionalised polyacrylamide nanoparticles: a support for the assembly of multifunctional nanodevices.

Giuntini F, Dumoulin F, Daly R, Ahsen V, Scanlan EM, Lavado AS, Aylott JW, Rosser GA, Beeby A, Boyle RW.

Nanoscale. 2012 Mar 21;4(6):2034-45. doi: 10.1039/c2nr11947a. Epub 2012 Feb 21.


Six3 is required for ependymal cell maturation.

Lavado A, Oliver G.

Development. 2011 Dec;138(24):5291-300. doi: 10.1242/dev.067470. Epub 2011 Nov 9.


Prox1 is required for granule cell maturation and intermediate progenitor maintenance during brain neurogenesis.

Lavado A, Lagutin OV, Chow LM, Baker SJ, Oliver G.

PLoS Biol. 2010 Aug 17;8(8). pii: e1000460. doi: 10.1371/journal.pbio.1000460.


Canal cristae growth and fiber extension to the outer hair cells of the mouse ear require Prox1 activity.

Fritzsch B, Dillard M, Lavado A, Harvey NL, Jahan I.

PLoS One. 2010 Feb 23;5(2):e9377. doi: 10.1371/journal.pone.0009377.


Six3 inactivation causes progressive caudalization and aberrant patterning of the mammalian diencephalon.

Lavado A, Lagutin OV, Oliver G.

Development. 2008 Feb;135(3):441-50. Epub 2007 Dec 19.


Prox1 expression patterns in the developing and adult murine brain.

Lavado A, Oliver G.

Dev Dyn. 2007 Feb;236(2):518-24.


Expression of Six3 Opposite Strand (Six3OS) during mouse embryonic development.

Geng X, Lavado A, Lagutin OV, Liu W, Oliver G.

Gene Expr Patterns. 2007 Jan;7(3):252-7. Epub 2006 Sep 26.


New animal models to study the role of tyrosinase in normal retinal development.

Lavado A, Montoliu L.

Front Biosci. 2006 Jan 1;11:743-52. Review.


A strategy to study tyrosinase transgenes in mouse melanocytes.

Lavado A, Matheu A, Serrano M, Montoliu L.

BMC Cell Biol. 2005 Apr 12;6(1):18.


Regional abnormalities in retinal development are associated with local ocular hypopigmentation.

Giménez E, Lavado A, Jeffery G, Montoliu L.

J Comp Neurol. 2005 May 16;485(4):338-47.


Molecular basis of the extreme dilution mottled mouse mutation: a combination of coding and noncoding genomic alterations.

Lavado A, Olivares C, García-Borrón JC, Montoliu L.

J Biol Chem. 2005 Feb 11;280(6):4817-24. Epub 2004 Nov 30.


A transgenic mouse model with inducible Tyrosinase gene expression using the tetracycline (Tet-on) system allows regulated rescue of abnormal chiasmatic projections found in albinism.

Giménez E, Lavado A, Giraldo P, Cozar P, Jeffery G, Montoliu L.

Pigment Cell Res. 2004 Aug;17(4):363-70. Erratum in: Pigment Cell Res. 2005 Jun;18(3):224.


Generation and phenotypic analysis of sigma receptor type I (sigma 1) knockout mice.

Langa F, Codony X, Tovar V, Lavado A, Giménez E, Cozar P, Cantero M, Dordal A, Hernández E, Pérez R, Monroy X, Zamanillo D, Guitart X, Montoliu L.

Eur J Neurosci. 2003 Oct;18(8):2188-96.


Tyrosinase gene expression is not detected in mouse brain outside the retinal pigment epithelium cells.

Giménez E, Lavado A, Giraldo P, Montoliu L.

Eur J Neurosci. 2003 Nov;18(9):2673-6.


Functional dissection of the mouse tyrosinase locus control region identifies a new putative boundary activity.

Giraldo P, Martínez A, Regales L, Lavado A, García-Díaz A, Alonso A, Busturia A, Montoliu L.

Nucleic Acids Res. 2003 Nov 1;31(21):6290-305.


3-hydroxypicolinaldehyde thiosemicarbazone as an analytical reagent for spectrophotometric determination of cobalt.

Pavón JM, Lavado A, Pino F.

Mikrochim Acta. 1976;(3-4 Pt 2):233-9. No abstract available.


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