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Items: 1 to 50 of 68

1.

Characterization of Cystic Fibrosis Airway Smooth Muscle Cell Proliferative and Contractile Activities.

Jang JH, Panariti A, O'Sullivan MJ, Pyrch M, Wong C, Lauzon AM, Martin JG.

Am J Physiol Lung Cell Mol Physiol. 2019 Sep 11. doi: 10.1152/ajplung.00090.2019. [Epub ahead of print]

PMID:
31508974
2.

Spreading of perturbations in myosin group kinetics along actin filaments.

Balassy Z, Lauzon AM, Hilbert L.

Proc Natl Acad Sci U S A. 2019 Aug 27;116(35):17336-17344. doi: 10.1073/pnas.1904164116. Epub 2019 Aug 12.

PMID:
31405981
3.

Rapid time-stamped analysis of filament motility.

Ijpma G, Balassy Z, Lauzon AM.

J Muscle Res Cell Motil. 2018 Dec;39(5-6):153-162. doi: 10.1007/s10974-019-09503-3. Epub 2019 Apr 10.

PMID:
30972524
4.

Contractile Properties of Intrapulmonary Airway Smooth Muscle in Cystic Fibrosis.

Matusovsky OS, Kachmar L, Ijpma G, Panariti A, Benedetti A, Martin JG, Lauzon AM.

Am J Respir Cell Mol Biol. 2019 Apr;60(4):434-444. doi: 10.1165/rcmb.2018-0005OC.

PMID:
30359078
5.

Maintenance of contractile function of isolated airway smooth muscle after cryopreservation.

Ijpma G, Liang CQ, Kachmar L, Panariti A, Benedetti A, Lavoie JP, Lauzon AM.

Am J Physiol Lung Cell Mol Physiol. 2018 Nov 1;315(5):L724-L733. doi: 10.1152/ajplung.00064.2018. Epub 2018 Aug 9.

PMID:
30091377
6.

Basic Fibroblast Growth Factor 2 Is a Determinant of CD4 T Cell-Airway Smooth Muscle Cell Communication through Membrane Conduits.

Farahnak S, McGovern TK, Kim R, O'Sullivan M, Chen B, Lee M, Yoshie H, Wang A, Jang J, Al Heialy S, Lauzon AM, Martin JG.

J Immunol. 2017 Nov 1;199(9):3086-3093. doi: 10.4049/jimmunol.1700164. Epub 2017 Sep 18.

7.

Epithelial Cells Induce a Cyclo-Oxygenase-1-Dependent Endogenous Reduction in Airway Smooth Muscle Contractile Phenotype.

O'Sullivan MJ, Gabriel E, Panariti A, Park CY, Ijpma G, Fredberg JJ, Lauzon AM, Martin JG.

Am J Respir Cell Mol Biol. 2017 Dec;57(6):683-691. doi: 10.1165/rcmb.2016-0427OC.

8.

Directional preference of airway smooth muscle mass increase in human asthmatic airways.

Ijpma G, Panariti A, Lauzon AM, Martin JG.

Am J Physiol Lung Cell Mol Physiol. 2017 Jun 1;312(6):L845-L854. doi: 10.1152/ajplung.00353.2016. Epub 2017 Mar 30.

9.

Airway hyperresponsiveness; smooth muscle as the principal actor.

Lauzon AM, Martin JG.

F1000Res. 2016 Mar 9;5. pii: F1000 Faculty Rev-306. doi: 10.12688/f1000research.7422.1. eCollection 2016. Review.

10.

Peripheral Airway Smooth Muscle, but Not the Trachealis, Is Hypercontractile in an Equine Model of Asthma.

Matusovsky OS, Kachmar L, Ijpma G, Bates G, Zitouni N, Benedetti A, Lavoie JP, Lauzon AM.

Am J Respir Cell Mol Biol. 2016 May;54(5):718-27. doi: 10.1165/rcmb.2015-0180OC.

11.

Nanotubes connect CD4+ T cells to airway smooth muscle cells: novel mechanism of T cell survival.

Al Heialy S, Zeroual M, Farahnak S, McGovern T, Risse PA, Novali M, Lauzon AM, Roman HN, Martin JG.

J Immunol. 2015 Jun 15;194(12):5626-34. doi: 10.4049/jimmunol.1401718. Epub 2015 May 1.

12.

Human trachealis and main bronchi smooth muscle are normoresponsive in asthma.

Ijpma G, Kachmar L, Matusovsky OS, Bates JH, Benedetti A, Martin JG, Lauzon AM.

Am J Respir Crit Care Med. 2015 Apr 15;191(8):884-93. doi: 10.1164/rccm.201407-1296OC.

13.

Phosphate and ADP differently inhibit coordinated smooth muscle myosin groups.

Hilbert L, Balassy Z, Zitouni NB, Mackey MC, Lauzon AM.

Biophys J. 2015 Feb 3;108(3):622-31. doi: 10.1016/j.bpj.2014.12.008.

14.

A microfluidic chamber to study the dynamics of muscle-contraction-specific molecular interactions.

Roman HN, Juncker D, Lauzon AM.

Anal Chem. 2015 Mar 3;87(5):2582-7. doi: 10.1021/ac503963r. Epub 2015 Feb 10.

PMID:
25629255
15.

Inhaled corticosteroids modulate the (+)insert smooth muscle myosin heavy chain in the equine asthmatic airways.

Boivin R, Vargas A, Lefebvre-Lavoie J, Lauzon AM, Lavoie JP.

Thorax. 2014 Dec;69(12):1113-9. doi: 10.1136/thoraxjnl-2014-205572. Epub 2014 Sep 9.

PMID:
25205586
16.

The role of caldesmon and its phosphorylation by ERK on the binding force of unphosphorylated myosin to actin.

Roman HN, Zitouni NB, Kachmar L, Benedetti A, Sobieszek A, Lauzon AM.

Biochim Biophys Acta. 2014 Nov;1840(11):3218-25. doi: 10.1016/j.bbagen.2014.07.024. Epub 2014 Aug 7.

17.

CD4+ T cells enhance the unloaded shortening velocity of airway smooth muscle by altering the contractile protein expression.

Matusovsky OS, Nakada EM, Kachmar L, Fixman ED, Lauzon AM.

J Physiol. 2014 Jul 15;592(14):2999-3012. doi: 10.1113/jphysiol.2014.270843. Epub 2014 Mar 31.

18.

Molecular mechanical differences between isoforms of contractile actin in the presence of isoforms of smooth muscle tropomyosin.

Hilbert L, Bates G, Roman HN, Blumenthal JL, Zitouni NB, Sobieszek A, Mackey MC, Lauzon AM.

PLoS Comput Biol. 2013 Oct;9(10):e1003273. doi: 10.1371/journal.pcbi.1003273. Epub 2013 Oct 24.

19.

The kinetics of mechanically coupled myosins exhibit group size-dependent regimes.

Hilbert L, Cumarasamy S, Zitouni NB, Mackey MC, Lauzon AM.

Biophys J. 2013 Sep 17;105(6):1466-74. doi: 10.1016/j.bpj.2013.07.054.

20.

Unphosphorylated calponin enhances the binding force of unphosphorylated myosin to actin.

Roman HN, Zitouni NB, Kachmar L, Ijpma G, Hilbert L, Matusovsky O, Benedetti A, Sobieszek A, Lauzon AM.

Biochim Biophys Acta. 2013 Oct;1830(10):4634-41. doi: 10.1016/j.bbagen.2013.05.042. Epub 2013 Jun 6.

21.

Forces measured with micro-fabricated cantilevers during actomyosin interactions produced by filaments containing different myosin isoforms and loop 1 structures.

Kalganov A, Shalabi N, Zitouni N, Kachmar LH, Lauzon AM, Rassier DE.

Biochim Biophys Acta. 2013 Mar;1830(3):2710-9.

PMID:
23671932
22.

Molecular, cellular, and muscle strip mechanics of the mdx mouse diaphragm.

Bates G, Sigurdardottir S, Kachmar L, Zitouni NB, Benedetti A, Petrof BJ, Rassier D, Lauzon AM.

Am J Physiol Cell Physiol. 2013 May 1;304(9):C873-80. doi: 10.1152/ajpcell.00220.2012. Epub 2013 Feb 20.

23.

Accumulating evidence for increased velocity of airway smooth muscle shortening in asthmatic airway hyperresponsiveness.

Ijpma G, Matusovsky O, Lauzon AM.

J Allergy (Cairo). 2012;2012:156909. doi: 10.1155/2012/156909. Epub 2012 Dec 25.

24.

Forces measured with micro-fabricated cantilevers during actomyosin interactions produced by filaments containing different myosin isoforms and loop 1 structures.

Kalganov A, Shalabi N, Zitouni N, Kachmar LH, Lauzon AM, Rassier DE.

Biochim Biophys Acta. 2013 Mar;1830(3):2710-2719. doi: 10.1016/j.bbagen.2012.11.022. Epub 2012 Dec 7.

PMID:
23220701
25.

A multi-scale approach to airway hyperresponsiveness: from molecule to organ.

Lauzon AM, Bates JH, Donovan G, Tawhai M, Sneyd J, Sanderson MJ.

Front Physiol. 2012 Jun 11;3:191. doi: 10.3389/fphys.2012.00191. eCollection 2012.

26.

Caffeine relaxes smooth muscle through actin depolymerization.

Tazzeo T, Bates G, Roman HN, Lauzon AM, Khasnis MD, Eto M, Janssen LJ.

Am J Physiol Lung Cell Mol Physiol. 2012 Aug 15;303(4):L334-42. doi: 10.1152/ajplung.00103.2012. Epub 2012 Jun 8.

27.

Ileal smooth muscle dysfunction and remodeling in cystic fibrosis.

Risse PA, Kachmar L, Matusovsky OS, Novali M, Gil FR, Javeshghani S, Keary R, Haston CK, Michoud MC, Martin JG, Lauzon AM.

Am J Physiol Gastrointest Liver Physiol. 2012 Jul;303(1):G1-8. doi: 10.1152/ajpgi.00356.2011. Epub 2012 Apr 26.

28.

Linear dimensions and volumes of human lungs obtained from CT images.

Kramer GH, Capello K, Bearrs B, Lauzon A, Normandeau L.

Health Phys. 2012 Apr;102(4):378-83. doi: 10.1097/HP.0b013e31823a13f1.

PMID:
22378198
29.

The rise of passive airway smooth muscle mechanics.

Ijpma G, Lauzon AM.

J Appl Physiol (1985). 2012 Feb;112(3):335-6. doi: 10.1152/japplphysiol.01338.2011. Epub 2011 Nov 3. No abstract available.

30.

A continuous-binding cross-linker model for passive airway smooth muscle.

Donovan GM, Bullimore SR, Elvin AJ, Tawhai MH, Bates JH, Lauzon AM, Sneyd J.

Biophys J. 2010 Nov 17;99(10):3164-71. doi: 10.1016/j.bpj.2010.09.031.

31.

Could an increase in airway smooth muscle shortening velocity cause airway hyperresponsiveness?

Bullimore SR, Siddiqui S, Donovan GM, Martin JG, Sneyd J, Bates JH, Lauzon AM.

Am J Physiol Lung Cell Mol Physiol. 2011 Jan;300(1):L121-31. doi: 10.1152/ajplung.00228.2010. Epub 2010 Oct 22.

32.

A multiscale, spatially distributed model of asthmatic airway hyper-responsiveness.

Politi AZ, Donovan GM, Tawhai MH, Sanderson MJ, Lauzon AM, Bates JH, Sneyd J.

J Theor Biol. 2010 Oct 21;266(4):614-24. doi: 10.1016/j.jtbi.2010.07.032. Epub 2010 Aug 4.

33.

Acute response of airway muscle to extreme temperature includes disruption of actin-myosin interaction.

Dyrda P, Tazzeo T, DoHarris L, Nilius B, Roman HN, Lauzon AM, Aziz T, Lukic D, Janssen LJ.

Am J Respir Cell Mol Biol. 2011 Feb;44(2):213-21. doi: 10.1165/rcmb.2009-0259OC. Epub 2010 Apr 15.

PMID:
20395634
34.

The effects of repeated allergen challenge on airway smooth muscle structural and molecular remodeling in a rat model of allergic asthma.

Labonté I, Hassan M, Risse PA, Tsuchiya K, Laviolette M, Lauzon AM, Martin JG.

Am J Physiol Lung Cell Mol Physiol. 2009 Oct;297(4):L698-705. doi: 10.1152/ajplung.00142.2009. Epub 2009 Jul 31.

35.

Transient oscillatory force-length behavior of activated airway smooth muscle.

Bates JH, Bullimore SR, Politi AZ, Sneyd J, Anafi RC, Lauzon AM.

Am J Physiol Lung Cell Mol Physiol. 2009 Aug;297(2):L362-72. doi: 10.1152/ajplung.00095.2009. Epub 2009 Jun 12.

36.

Myosin, transgelin, and myosin light chain kinase: expression and function in asthma.

Léguillette R, Laviolette M, Bergeron C, Zitouni N, Kogut P, Solway J, Kachmar L, Hamid Q, Lauzon AM.

Am J Respir Crit Care Med. 2009 Feb 1;179(3):194-204. doi: 10.1164/rccm.200609-1367OC. Epub 2008 Nov 14.

37.

Affinity for MgADP and force of unbinding from actin of myosin purified from tonic and phasic smooth muscle.

Léguillette R, Zitouni NB, Govindaraju K, Fong LM, Lauzon AM.

Am J Physiol Cell Physiol. 2008 Sep;295(3):C653-60. doi: 10.1152/ajpcell.00100.2008. Epub 2008 Jul 9.

38.

Molecular mechanics of smooth muscle contractile proteins in airway hyperresponsiveness and asthma.

Léguillette R, Lauzon AM.

Proc Am Thorac Soc. 2008 Jan 1;5(1):40-6. Review.

PMID:
18094083
39.

Smooth muscle molecular mechanics in airway hyperresponsiveness and asthma.

Gil FR, Lauzon AM.

Can J Physiol Pharmacol. 2007 Jan;85(1):133-40. Review.

PMID:
17487252
40.

Airway smooth muscle dynamics: a common pathway of airway obstruction in asthma.

An SS, Bai TR, Bates JH, Black JL, Brown RH, Brusasco V, Chitano P, Deng L, Dowell M, Eidelman DH, Fabry B, Fairbank NJ, Ford LE, Fredberg JJ, Gerthoffer WT, Gilbert SH, Gosens R, Gunst SJ, Halayko AJ, Ingram RH, Irvin CG, James AL, Janssen LJ, King GG, Knight DA, Lauzon AM, Lakser OJ, Ludwig MS, Lutchen KR, Maksym GN, Martin JG, Mauad T, McParland BE, Mijailovich SM, Mitchell HW, Mitchell RW, Mitzner W, Murphy TM, Paré PD, Pellegrino R, Sanderson MJ, Schellenberg RR, Seow CY, Silveira PS, Smith PG, Solway J, Stephens NL, Sterk PJ, Stewart AG, Tang DD, Tepper RS, Tran T, Wang L.

Eur Respir J. 2007 May;29(5):834-60. Review.

41.

Parenchymal tethering, airway wall stiffness, and the dynamics of bronchoconstriction.

Bates JH, Lauzon AM.

J Appl Physiol (1985). 2007 May;102(5):1912-20. Epub 2007 Jan 4.

42.

Smooth muscle myosin isoform expression and LC20 phosphorylation in innate rat airway hyperresponsiveness.

Gil FR, Zitouni NB, Azoulay E, Maghni K, Lauzon AM.

Am J Physiol Lung Cell Mol Physiol. 2006 Nov;291(5):L932-40. Epub 2006 Jun 9.

43.

(+)Insert smooth muscle myosin heavy chain (SM-B): from single molecule to human.

Low R, Léguillette R, Lauzon AM.

Int J Biochem Cell Biol. 2006;38(11):1862-74. Epub 2006 Apr 6. Review.

PMID:
16716643
44.

(+)Insert smooth muscle myosin heavy chain (SM-B) isoform expression in human tissues.

Léguillette R, Gil FR, Zitouni N, Lajoie-Kadoch S, Sobieszek A, Lauzon AM.

Am J Physiol Cell Physiol. 2005 Nov;289(5):C1277-85. Epub 2005 Jul 6.

45.

Modeling the oscillation dynamics of activated airway smooth muscle strips.

Bates JH, Lauzon AM.

Am J Physiol Lung Cell Mol Physiol. 2005 Nov;289(5):L849-55. Epub 2005 May 13.

46.

On the terminology for describing the length-force relationship and its changes in airway smooth muscle.

Bai TR, Bates JH, Brusasco V, Camoretti-Mercado B, Chitano P, Deng LH, Dowell M, Fabry B, Ford LE, Fredberg JJ, Gerthoffer WT, Gilbert SH, Gunst SJ, Hai CM, Halayko AJ, Hirst SJ, James AL, Janssen LJ, Jones KA, King GG, Lakser OJ, Lambert RK, Lauzon AM, Lutchen KR, Maksym GN, Meiss RA, Mijailovich SM, Mitchell HW, Mitchell RW, Mitzner W, Murphy TM, Paré PD, Schellenberg RR, Seow CY, Sieck GC, Smith PG, Smolensky AV, Solway J, Stephens NL, Stewart AG, Tang DD, Wang L.

J Appl Physiol (1985). 2004 Dec;97(6):2029-34. Review.

47.

Time course of airway mechanics of the (+)insert myosin isoform knockout mouse.

Tuck SA, Maghni K, Poirier A, Babu GJ, Periasamy M, Bates JH, Leguillette R, Lauzon AM.

Am J Respir Cell Mol Biol. 2004 Mar;30(3):326-32. Epub 2003 Sep 4.

PMID:
12959948
48.
49.

Kinetics of respiratory system elastance after airway challenge in dogs.

Lauzon AM, Bates JH.

J Appl Physiol (1985). 2000 Nov;89(5):2023-9.

50.

Helium and sulfur hexafluoride bolus washin in short-term microgravity.

Dutrieue B, Lauzon AM, Verbanck S, Elliott AR, West JB, Paiva M, Prisk GK.

J Appl Physiol (1985). 1999 May;86(5):1594-602.

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