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The diagnostic usefulness of the combined COMPASS 31 questionnaire and electrochemical skin conductance for diabetic cardiovascular autonomic neuropathy and diabetic polyneuropathy.

D'Amato C, Greco C, Lombardo G, Frattina V, Campo M, Cefalo CMA, Izzo V, Lauro D, Spallone V.

J Peripher Nerv Syst. 2020 Mar;25(1):44-53. doi: 10.1111/jns.12366. Epub 2020 Feb 14.


Peroxiredoxin 6 Is a Key Antioxidant Enzyme in Modulating the Link between Glycemic and Lipogenic Metabolism.

Arriga R, Pacifici F, Capuani B, Coppola A, Orlandi A, Scioli MG, Pastore D, Andreadi A, Sbraccia P, Tesauro M, Daniele ND, Sconocchia G, Donadel G, Bellia A, Della-Morte D, Lauro D.

Oxid Med Cell Longev. 2019 Dec 19;2019:9685607. doi: 10.1155/2019/9685607. eCollection 2019.


Morning blood pressure surge is associated with autonomic neuropathy and peripheral vascular disease in patients with diabetes.

Di Gennaro F, D'Amato C, Morganti R, Greco C, Longo S, Corradini D, Lauro D, Spallone V.

J Hum Hypertens. 2019 Oct 17. doi: 10.1038/s41371-019-0270-3. [Epub ahead of print]


Proposed Tandem Effect of Physical Activity and Sirtuin 1 and 3 Activation in Regulating Glucose Homeostasis.

Pacifici F, Di Cola D, Pastore D, Abete P, Guadagni F, Donadel G, Bellia A, Esposito E, Salimei C, Sinibaldi Salimei P, Ricordi C, Lauro D, Della-Morte D.

Int J Mol Sci. 2019 Sep 25;20(19). pii: E4748. doi: 10.3390/ijms20194748. Review.


In vitro elimination of epidermal growth factor receptor-overexpressing cancer cells by CD32A-chimeric receptor T cells in combination with cetuximab or panitumumab.

Caratelli S, Arriga R, Sconocchia T, Ottaviani A, Lanzilli G, Pastore D, Cenciarelli C, Venditti A, Del Principe MI, Lauro D, Landoni E, Du H, Savoldo B, Ferrone S, Dotti G, Sconocchia G.

Int J Cancer. 2020 Jan 1;146(1):236-247. doi: 10.1002/ijc.32663. Epub 2019 Oct 12.


CD16-158-valine chimeric receptor T cells overcome the resistance of KRAS-mutated colorectal carcinoma cells to cetuximab.

Arriga R, Caratelli S, Lanzilli G, Ottaviani A, Cenciarelli C, Sconocchia T, Spagnoli GC, Iezzi G, Roselli M, Lauro D, Coppola A, Dotti G, Ferrone S, Sconocchia G.

Int J Cancer. 2020 May 1;146(9):2531-2538. doi: 10.1002/ijc.32618. Epub 2019 Aug 30.


Age-Dependent Levels of Protein Kinase Cs in Brain: Reduction of Endogenous Mechanisms of Neuroprotection.

Pastore D, Pacifici F, Dave KR, Palmirotta R, Bellia A, Pasquantonio G, Guadagni F, Donadel G, Di Daniele N, Abete P, Lauro D, Rundek T, Perez-Pinzon MA, Della-Morte D.

Int J Mol Sci. 2019 Jul 19;20(14). pii: E3544. doi: 10.3390/ijms20143544. Review.


Long-term observational study on the impact of GLP-1R agonists on lung function in diabetic patients.

Rogliani P, Matera MG, Calzetta L, Hanania NA, Page C, Rossi I, Andreadi A, Galli A, Coppola A, Cazzola M, Lauro D.

Respir Med. 2019 Jul - Aug;154:86-92. doi: 10.1016/j.rmed.2019.06.015. Epub 2019 Jun 18.


Fine-scale haplotype mapping of MUT, AACS, SLC6A15 and PRKCA genes indicates association with insulin resistance of metabolic syndrome and relationship with branched chain amino acid metabolism or regulation.

Haydar S, Grigorescu F, Vintilă M, Cogne Y, Lautier C, Tutuncu Y, Brun JF, Robine JM, Pugeat M, Normand C, Poucheret P, Gheorghiu ML, Georgescu C, Badiu C, Băculescu N, Renard E, Ylli D, Badiou S, Sutra T, Cristol JP, Mercier J, Gomis R, Macias JM, Litvinov S, Khusnutdinova E, Poiana C, Pasquali R, Lauro D, Sesti G, Prudente S, Trischitta V, Tsatsoulis A, Abdelhak S, Barakat A, Zenati A, Ylli A, Satman I, Kanninen T, Rinato Y, Missoni S.

PLoS One. 2019 Mar 26;14(3):e0214122. doi: 10.1371/journal.pone.0214122. eCollection 2019.


Insulin autoimmune syndrome in an Argentine woman taking α-lipoic acid: A case report and review of the literature.

Izzo V, Greco C, Corradini D, Infante M, Staltari MT, Romano M, Bellia A, Lauro D, Uccioli L.

SAGE Open Med Case Rep. 2018 Dec 26;6:2050313X18819601. doi: 10.1177/2050313X18819601. eCollection 2018.


Glucagon Like Peptide 1 and MicroRNA in Metabolic Diseases: Focusing on GLP1 Action on miRNAs.

Capuani B, Pacifici F, Della-Morte D, Lauro D.

Front Endocrinol (Lausanne). 2018 Dec 7;9:719. doi: 10.3389/fendo.2018.00719. eCollection 2018. Review.


Branched-Chain Amino Acid Database Integrated in MEDIPAD Software as a Tool for Nutritional Investigation of Mediterranean Populations.

Haydar S, Paillot T, Fagot C, Cogne Y, Fountas A, Tutuncu Y, Vintila M, Tsatsoulis A, Thanh Chi P, Garandeau P, Chetea D, Badiu C, Gheorghiu M, Ylli D, Lautier C, Jarec M, Monnier L, Normand C, Šarac J, Barakat A, Missoni S, Pugeat M, Poucheret P, Hanzu F, Gomis R, Macias JM, Litvinov S, Khusnutdinova E, Poiana C, Pasquali R, Lauro D, Sesti G, Trischitta V, Abdelhak S, Zenati A, Ylli A, Satman I, Kanninen T, Rinato Y, Grigorescu F.

Nutrients. 2018 Oct 1;10(10). pii: E1392. doi: 10.3390/nu10101392.


Pleiotropic effects of hypoglycemic agents: implications in asthma and COPD.

Rogliani P, Ora J, Di Daniele N, Lauro D.

Curr Opin Pharmacol. 2018 Jun;40:34-38. doi: 10.1016/j.coph.2018.01.002. Epub 2018 Feb 9. Review.


Parathyroid hormone in surgery-induced weight loss: no glucometabolic effects but potential adaptive response to skeletal loading.

Guglielmi V, Bellia A, Gentileschi P, Lombardo M, D'Adamo M, Lauro D, Sbraccia P.

Endocrine. 2018 Feb;59(2):288-295. doi: 10.1007/s12020-017-1477-0. Epub 2017 Nov 22.


Peroxiredoxin6, a Multitask Antioxidant Enzyme Involved in the Pathophysiology of Chronic Noncommunicable Diseases.

Pacifici F, Della Morte D, Capuani B, Pastore D, Bellia A, Sbraccia P, Di Daniele N, Lauro R, Lauro D.

Antioxid Redox Signal. 2019 Jan 20;30(3):399-414. doi: 10.1089/ars.2017.7427. Epub 2018 Jan 2.


Association between a MIR499A polymorphism and diabetic neuropathy in type 2 diabetes.

Ciccacci C, Latini A, Greco C, Politi C, D'Amato C, Lauro D, Novelli G, Borgiani P, Spallone V.

J Diabetes Complications. 2018 Jan;32(1):11-17. doi: 10.1016/j.jdiacomp.2017.10.011. Epub 2017 Oct 26.


FGF-2b and h-PL Transform Duct and Non-Endocrine Human Pancreatic Cells into Endocrine Insulin Secreting Cells by Modulating Differentiating Genes.

Donadel G, Pastore D, Della-Morte D, Capuani B, Lombardo MF, Pacifici F, Bugliani M, Grieco FA, Marchetti P, Lauro D.

Int J Mol Sci. 2017 Oct 25;18(11). pii: E2234. doi: 10.3390/ijms18112234.


Effects on the incidence of cardiovascular events of the addition of pioglitazone versus sulfonylureas in patients with type 2 diabetes inadequately controlled with metformin (TOSCA.IT): a randomised, multicentre trial.

Vaccaro O, Masulli M, Nicolucci A, Bonora E, Del Prato S, Maggioni AP, Rivellese AA, Squatrito S, Giorda CB, Sesti G, Mocarelli P, Lucisano G, Sacco M, Signorini S, Cappellini F, Perriello G, Babini AC, Lapolla A, Gregori G, Giordano C, Corsi L, Buzzetti R, Clemente G, Di Cianni G, Iannarelli R, Cordera R, La Macchia O, Zamboni C, Scaranna C, Boemi M, Iovine C, Lauro D, Leotta S, Dall'Aglio E, Cannarsa E, Tonutti L, Pugliese G, Bossi AC, Anichini R, Dotta F, Di Benedetto A, Citro G, Antenucci D, Ricci L, Giorgino F, Santini C, Gnasso A, De Cosmo S, Zavaroni D, Vedovato M, Consoli A, Calabrese M, di Bartolo P, Fornengo P, Riccardi G; Thiazolidinediones Or Sulfonylureas Cardiovascular Accidents Intervention Trial (TOSCA.IT) study group; Italian Diabetes Society.

Lancet Diabetes Endocrinol. 2017 Nov;5(11):887-897. doi: 10.1016/S2213-8587(17)30317-0. Epub 2017 Sep 13. Erratum in: Lancet Diabetes Endocrinol. 2017 Nov;5(11):e7.


Suboptimal use of statins for secondary cardiovascular prevention: a "planetary" issue.

Bellia A, Della-Morte D, Lauro D.

Intern Emerg Med. 2017 Dec;12(8):1091-1092. doi: 10.1007/s11739-017-1749-y. Epub 2017 Sep 14. No abstract available.


Drug interactions in users of tablet vs. oral liquid levothyroxine formulations: a real-world evidence study in primary care.

Guglielmi V, Bellia A, Bianchini E, Medea G, Cricelli I, Sbraccia P, Lauro D, Cricelli C, Lapi F.

Endocrine. 2018 Mar;59(3):585-592. doi: 10.1007/s12020-017-1412-4. Epub 2017 Sep 14.


Effects of parasitic infection and reproduction on corticosterone plasma levels in Galápagos land iguanas, Conolophus marthae and C. subcristatus.

Onorati M, Sancesario G, Pastore D, Bernardini S, Cruz M, Carrión JE, Carosi M, Vignoli L, Lauro D, Gentile G.

Ecol Evol. 2017 Jul 5;7(15):6046-6055. doi: 10.1002/ece3.3077. eCollection 2017 Aug.


Targeting Mechanisms Linking COPD to Type 2 Diabetes Mellitus.

Cazzola M, Rogliani P, Calzetta L, Lauro D, Page C, Matera MG.

Trends Pharmacol Sci. 2017 Oct;38(10):940-951. doi: 10.1016/ Epub 2017 Aug 7. Review.


Exercise individualized by TRIMPi method reduces arterial stiffness in early onset type 2 diabetic patients: A randomized controlled trial with aerobic interval training.

Bellia A, Iellamo F, De Carli E, Andreadi A, Padua E, Lombardo M, Annino G, Campoli F, Tartaglione S, D'Ottavio S, Della-Morte D, Lauro D.

Int J Cardiol. 2017 Dec 1;248:314-319. doi: 10.1016/j.ijcard.2017.06.065. Epub 2017 Jun 17.


Effectiveness of adherence to lipid lowering therapy on LDL-cholesterol in patients with very high cardiovascular risk: A real-world evidence study in primary care.

Guglielmi V, Bellia A, Pecchioli S, Della-Morte D, Parretti D, Cricelli I, Medea G, Sbraccia P, Lauro D, Cricelli C, Lapi F.

Atherosclerosis. 2017 Aug;263:36-41. doi: 10.1016/j.atherosclerosis.2017.05.018. Epub 2017 May 20.


FCγ Chimeric Receptor-Engineered T Cells: Methodology, Advantages, Limitations, and Clinical Relevance.

Caratelli S, Sconocchia T, Arriga R, Coppola A, Lanzilli G, Lauro D, Venditti A, Del Principe MI, Buccisano F, Maurillo L, Ferrone S, Sconocchia G.

Front Immunol. 2017 Apr 27;8:457. doi: 10.3389/fimmu.2017.00457. eCollection 2017. Review.


Sex-Genetic Interaction in the Risk for Cerebrovascular Disease.

Pastore D, Pacifici F, Capuani B, Palmirotta R, Dong C, Coppola A, Abete P, Roselli M, Sbraccia P, Guadagni F, Lauro D, Rundek T, Della-Morte D.

Curr Med Chem. 2017;24(24):2687-2699. doi: 10.2174/0929867324666170417100318. Review.


Retinal neurodegeneration in patients with type 1 diabetes mellitus: the role of glycemic variability.

Picconi F, Parravano M, Ylli D, Pasqualetti P, Coluzzi S, Giordani I, Malandrucco I, Lauro D, Scarinci F, Giorno P, Varano M, Frontoni S.

Acta Diabetol. 2017 May;54(5):489-497. doi: 10.1007/s00592-017-0971-4. Epub 2017 Feb 25.


Psychological characteristics of early-stage melanoma patients: a cross-sectional study on 204 patients.

Tesio V, Ribero S, Castelli L, Bassino S, Leombruni P, Caliendo V, Grassi M, Lauro D, Macripò G, Torta RGV.

Melanoma Res. 2017 Jun;27(3):277-280. doi: 10.1097/CMR.0000000000000348.


Validation of the Composite Autonomic Symptom Score 31 (COMPASS 31) for the assessment of symptoms of autonomic neuropathy in people with diabetes.

Greco C, Di Gennaro F, D'Amato C, Morganti R, Corradini D, Sun A, Longo S, Lauro D, Pierangeli G, Cortelli P, Spallone V.

Diabet Med. 2017 Jun;34(6):834-838. doi: 10.1111/dme.13310. Epub 2017 Jan 19.


Polyphenol intake and cardiovascular risk factors in a population with type 2 diabetes: The TOSCA.IT study.

Vitale M, Vaccaro O, Masulli M, Bonora E, Del Prato S, Giorda CB, Nicolucci A, Squatrito S, Auciello S, Babini AC, Bani L, Buzzetti R, Cannarsa E, Cignarelli M, Cigolini M, Clemente G, Cocozza S, Corsi L, D'Angelo F, Dall'Aglio E, Di Cianni G, Fontana L, Gregori G, Grioni S, Giordano C, Iannarelli R, Iovine C, Lapolla A, Lauro D, Laviola L, Mazzucchelli C, Signorini S, Tonutti L, Trevisan R, Zamboni C, Riccardi G, Rivellese AA; TOSCA.IT Study Group.

Clin Nutr. 2017 Dec;36(6):1686-1692. doi: 10.1016/j.clnu.2016.11.002. Epub 2016 Nov 14.


Recurrent transient global amnesia as presenting symptoms of CADASIL.

Pradotto L, Orsi L, Mencarelli M, Caglio M, Lauro D, Milesi A, Di Blasio A, Mauro A.

Clin Case Rep. 2016 Sep 28;4(11):1045-1048. eCollection 2016 Nov.


Genotypic and phenotypic heterogeneity in Streptococcus mutans isolated from diabetic patients in Rome, Italy.

De A, Pasquantonio G, Cerroni L, Petrelli D, Lauro D, Longhi M, Vitali LA.

Springerplus. 2016 Oct 13;5(1):1794. eCollection 2016.


What is the actual epidemiology of familial hypercholesterolemia in Italy? Evidence from a National Primary Care Database.

Guglielmi V, Bellia A, Pecchioli S, Medea G, Parretti D, Lauro D, Sbraccia P, Federici M, Cricelli I, Cricelli C, Lapi F.

Int J Cardiol. 2016 Nov 15;223:701-705. doi: 10.1016/j.ijcard.2016.08.269. Epub 2016 Aug 17.


Severe hypoglycemia in patients with known diabetes requiring emergency department care: A report from an Italian multicenter study.

Mantovani A, Grani G, Chioma L, Vancieri G, Giordani I, Rendina R, Rinaldi ME, Andreadi A, Coccaro C, Boccardo C, Fraenza C, Bertazzoni G, Bellia A, Zoppini G, Targher G, Baroni MG, Lauro D, D'Armiento M, Bonora E.

J Clin Transl Endocrinol. 2016 Aug 20;5:46-52. doi: 10.1016/j.jcte.2016.08.004. eCollection 2016 Sep.


Role of KIR and CD16A genotypes in colorectal carcinoma genetic risk and clinical stage.

Canossi A, Aureli A, Del Beato T, Rossi P, Franceschilli L, De Sanctis F, Sileri P, di Lorenzo N, Buonomo O, Lauro D, Venditti A, Sconocchia G.

J Transl Med. 2016 Aug 12;14(1):239. doi: 10.1186/s12967-016-1001-y.


The role of epsilon PKC in acute and chronic diseases: Possible pharmacological implications of its modulators.

Capuani B, Pacifici F, Pastore D, Palmirotta R, Donadel G, Arriga R, Bellia A, Di Daniele N, Rogliani P, Abete P, Sbraccia P, Guadagni F, Lauro D, Della-Morte D.

Pharmacol Res. 2016 Sep;111:659-667. doi: 10.1016/j.phrs.2016.07.029. Epub 2016 Jul 25. Review.


Plasma concentrations of progesterone and estradiol and the relation to reproduction in Galápagos land iguanas, Conolophus marthae and C. subcristatus (Squamata, Iguanidae).

Onorati M, Sancesario G, Pastore D, Bernardini S, Carrión JE, Carosi M, Vignoli L, Lauro D, Gentile G.

Anim Reprod Sci. 2016 Sep;172:105-13. doi: 10.1016/j.anireprosci.2016.07.007. Epub 2016 Jul 15.


Glucagon-Like Peptide 1 Receptor: A Novel Pharmacological Target for Treating Human Bronchial Hyperresponsiveness.

Rogliani P, Calzetta L, Capuani B, Facciolo F, Cazzola M, Lauro D, Matera MG.

Am J Respir Cell Mol Biol. 2016 Dec;55(6):804-814.


Sirtuins and Cancer: Role in the Epithelial-Mesenchymal Transition.

Palmirotta R, Cives M, Della-Morte D, Capuani B, Lauro D, Guadagni F, Silvestris F.

Oxid Med Cell Longev. 2016;2016:3031459. doi: 10.1155/2016/3031459. Epub 2016 Jun 9. Review.


Diabetic peripheral neuropathic pain is a stronger predictor of depression than other diabetic complications and comorbidities.

D'Amato C, Morganti R, Greco C, Di Gennaro F, Cacciotti L, Longo S, Mataluni G, Lauro D, Marfia GA, Spallone V.

Diab Vasc Dis Res. 2016 Nov;13(6):418-428. Epub 2016 Jun 22.


Obesity and kidney disease: Beyond the hyperfiltration.

Mascali A, Franzese O, Nisticò S, Campia U, Lauro D, Cardillo C, Di Daniele N, Tesauro M.

Int J Immunopathol Pharmacol. 2016 Sep;29(3):354-63. doi: 10.1177/0394632016643550. Epub 2016 Apr 4.


Late-onset panhypopituitarism in a 72-year-old male patient treated with ipilimumab for metastatic melanoma: a case report.

Vancieri G, Bellia A, Lauro D.

J Endocrinol Invest. 2016 Jul;39(7):805-6. doi: 10.1007/s40618-016-0439-3. Epub 2016 Feb 16. No abstract available.


T lymphocytes engineered to express a CD16-chimeric antigen receptor redirect T-cell immune responses against immunoglobulin G-opsonized target cells.

D'Aloia MM, Caratelli S, Palumbo C, Battella S, Arriga R, Lauro D, Palmieri G, Sconocchia G, Alimandi M.

Cytotherapy. 2016 Feb;18(2):278-90. doi: 10.1016/j.jcyt.2015.10.014. Epub 2015 Dec 17.


Enhancement of anti-leukemia activity of NK cells in vitro and in vivo by inhibition of leukemia cell-induced NK cell damage.

Arriga R, Caratelli S, Coppola A, Spagnoli GC, Venditti A, Amadori S, Lanzilli G, Lauro D, Palomba P, Sconocchia T, Del Principe MI, Maurillo L, Buccisano F, Capuani B, Ferrone S, Sconocchia G.

Oncotarget. 2016 Jan 12;7(2):2070-9. doi: 10.18632/oncotarget.6529.


SGK-1 protects kidney cells against apoptosis induced by ceramide and TNF-α.

Pastore D, Della-Morte D, Coppola A, Capuani B, Lombardo MF, Pacifici F, Ferrelli F, Arriga R, Mammi C, Federici M, Bellia A, Di Daniele N, Tesauro M, Donadel G, Noto D, Sbraccia P, Sconocchia G, Lauro D.

Cell Death Dis. 2015 Sep 17;6:e1890. doi: 10.1038/cddis.2015.232.


Influence of dietary fat and carbohydrates proportions on plasma lipids, glucose control and low-grade inflammation in patients with type 2 diabetes-The TOSCA.IT Study.

Vitale M, Masulli M, Rivellese AA, Babini AC, Boemi M, Bonora E, Buzzetti R, Ciano O, Cignarelli M, Cigolini M, Clemente G, Citro G, Corsi L, Dall'Aglio E, Del Prato S, Di Cianni G, Dolci MA, Giordano C, Iannarelli R, Iovine C, Lapolla A, Lauro D, Leotta S, Mazzucchelli C, Montani V, Perriello G, Romano G, Romeo F, Santarelli L, di Cola RS, Squatrito S, Tonutti L, Trevisan R, Turco AA, Zamboni C, Riccardi G, Vaccaro O.

Eur J Nutr. 2016 Jun;55(4):1645-51. doi: 10.1007/s00394-015-0983-1. Epub 2015 Aug 25.


Role of Serum and Glucocorticoid-Inducible Kinase (SGK)-1 in Senescence: A Novel Molecular Target Against Age-Related Diseases.

Lauro D, Pastore D, Capuani B, Pacifici F, Palmirotta R, Abete P, Roselli M, Bellia A, Federici M, Di Daniele N, Sbraccia P, Guadagni F, Lauro R, Della-Morte D.

Curr Med Chem. 2015;22(33):3765-88. Review.


Omental adipose tissue fibrosis and insulin resistance in severe obesity.

Guglielmi V, Cardellini M, Cinti F, Corgosinho F, Cardolini I, D'Adamo M, Zingaretti MC, Bellia A, Lauro D, Gentileschi P, Federici M, Cinti S, Sbraccia P.

Nutr Diabetes. 2015 Aug 10;5:e175. doi: 10.1038/nutd.2015.22.


Serum- and Glucocorticoid-Inducible Kinase 1 Delay the Onset of Endothelial Senescence by Directly Interacting with Human Telomerase Reverse Transcriptase.

Basello K, Pacifici F, Capuani B, Pastore D, Lombardo MF, Ferrelli F, Coppola A, Donadel G, Arriga R, Sconocchia G, Bellia A, Rogliani P, Federici M, Sbraccia P, Lauro D, Della-Morte D.

Rejuvenation Res. 2016 Feb;19(1):79-89. doi: 10.1089/rej.2015.1726.


NK Cell Inflammation in the Clinical Outcome of Colorectal Carcinoma.

Coppola A, Arriga R, Lauro D, Del Principe MI, Buccisano F, Maurillo L, Palomba P, Venditti A, Sconocchia G.

Front Med (Lausanne). 2015 May 26;2:33. doi: 10.3389/fmed.2015.00033. eCollection 2015. Review.

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