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An international multicenter study to evaluate reproducibility of automated scoring for assessment of Ki67 in breast cancer.

Rimm DL, Leung SCY, McShane LM, Bai Y, Bane AL, Bartlett JMS, Bayani J, Chang MC, Dean M, Denkert C, Enwere EK, Galderisi C, Gholap A, Hugh JC, Jadhav A, Kornaga EN, Laurinavicius A, Levenson R, Lima J, Miller K, Pantanowitz L, Piper T, Ruan J, Srinivasan M, Virk S, Wu Y, Yang H, Hayes DF, Nielsen TO, Dowsett M.

Mod Pathol. 2019 Jan;32(1):59-69. doi: 10.1038/s41379-018-0109-4. Epub 2018 Aug 24.


The Triarchic Psychopathy Measure: An examination in a Lithuanian inmate sample.

Sellbom M, Laurinavičius A, Ustinavičiūtė L, Laurinaitytė I.

Psychol Assess. 2018 Jul;30(7):e10-e20. doi: 10.1037/pas0000603.


Impact of self-reported fasting duration on lipid profile variability, cardiovascular risk stratification and metabolic syndrome diagnosis.

Janovsky CCPS, Laurinavicius A, Cesena F, Valente V, Ferreira CE, Mangueira C, Conceição R, Santos RD, Bittencourt MS.

Arch Endocrinol Metab. 2018 Apr 5;62(2):187-192. doi: 10.20945/2359-3997000000023. Print 2018 Mar-Apr.


Significance of Notch and Wnt signaling for chemoresistance of colorectal cancer cells HCT116.

Kukcinaviciute E, Jonusiene V, Sasnauskiene A, Dabkeviciene D, Eidenaite E, Laurinavicius A.

J Cell Biochem. 2018 Jul;119(7):5913-5920. doi: 10.1002/jcb.26783. Epub 2018 Apr 10.


Statin Eligibility in Primary Prevention: From a Risk-Based Strategy to a Personalized Approach Based on the Predicted Benefit.

Cesena FHY, Laurinavicius AG, Valente VA, Conceição RD, Nasir K, Santos RD, Bittencourt MS.

Am J Cardiol. 2018 Jun 1;121(11):1315-1320. doi: 10.1016/j.amjcard.2018.02.011. Epub 2018 Mar 1.


Low-density lipoprotein-cholesterol lowering in individuals at intermediate cardiovascular risk: Percent reduction or target level?

Cesena FHY, Laurinavicius AG, Valente VA, Conceição RD, Santos RD, Bittencourt MS.

Clin Cardiol. 2018 Mar;41(3):333-338. doi: 10.1002/clc.22868. Epub 2018 Mar 25.


Association between clinical factors and self-underestimation of cardiovascular risk in subjects submitted to a routine health evaluation.

Helou TN, Santos RD, Laurinavicius AG, Bittencourt MS, Pesaro AEP, Franco FGM, Conceição RDO, Carvalho JAM, Silva FMF, Wajngarten M, Katz M.

Clin Cardiol. 2018 Jan;41(1):28-33. doi: 10.1002/clc.22841. Epub 2018 Jan 22.


Decreased expression of MT1E is a potential biomarker of prostate cancer progression.

Demidenko R, Daniunaite K, Bakavicius A, Sabaliauskaite R, Skeberdyte A, Petroska D, Laurinavicius A, Jankevicius F, Lazutka JR, Jarmalaite S.

Oncotarget. 2017 Jun 27;8(37):61709-61718. doi: 10.18632/oncotarget.18683. eCollection 2017 Sep 22.


Teaching Digital Pathology: The International School of Digital Pathology and Proposed Syllabus.

Mea VD, Carbone A, Di Loreto C, Bueno G, De Paoli P, García-Rojo M, de Mena D, Gloghini A, Ilyas M, Laurinavicius A, Rasmusson A, Milione M, Dolcetti R, Pagani M, Stoppini A, Sulfaro S, Bartolo M, Mazzon E, Soyer HP, Pantanowitz L.

J Pathol Inform. 2017 Jul 25;8:27. doi: 10.4103/jpi.jpi_17_17. eCollection 2017.


The impact of IgM deposits on the outcome of Nephrotic syndrome in children.

Juozapaite S, Cerkauskiene R, Laurinavicius A, Jankauskiene A.

BMC Nephrol. 2017 Aug 3;18(1):260. doi: 10.1186/s12882-017-0674-7.


Association of subclinical inflammation, glycated hemoglobin and risk for obstructive sleep apnea syndrome.

D'Aurea CVR, Cerazi BGA, Laurinavicius AG, Janovsky CCPS, Conceição RDO, Santos RD, Bittencourt MS.

Einstein (Sao Paulo). 2017 Apr-Jun;15(2):136-140. doi: 10.1590/S1679-45082017AO3900. English, Portuguese.


Automated Image Analysis of HER2 Fluorescence In Situ Hybridization to Refine Definitions of Genetic Heterogeneity in Breast Cancer Tissue.

Radziuviene G, Rasmusson A, Augulis R, Lesciute-Krilaviciene D, Laurinaviciene A, Clim E, Laurinavicius A.

Biomed Res Int. 2017;2017:2321916. doi: 10.1155/2017/2321916. Epub 2017 May 28.


The Expected Cardiovascular Benefit of Plasma Cholesterol Lowering with or Without LDL-C Targets in Healthy Individuals at Higher Cardiovascular Risk.

Cesena FHY, Laurinavicius AG, Valente VA, Conceição RD, Santos RD, Bittencourt MS.

Arq Bras Cardiol. 2017 Jun;108(6):518-525. doi: 10.5935/abc.20170089. English, Portuguese.


Cardiovascular Risk Stratification and Statin Eligibility Based on the Brazilian vs. North American Guidelines on Blood Cholesterol Management.

Cesena FHY, Laurinavicius AG, Valente VA, Conceição RD, Santos RD, Bittencourt MS.

Arq Bras Cardiol. 2017 Jun;108(6):508-517. doi: 10.5935/abc.20170088. English, Portuguese.


Persistent Depressive Symptoms are Independent Predictors of Low-Grade Inflammation Onset Among Healthy Individuals.

Franco FGM, Laurinavicius AG, Lotufo PA, Conceição RD, Morita F, Katz M, Wajngarten M, Carvalho JAM, Bosworth HB, Santos RD.

Arq Bras Cardiol. 2017 Jun 29:0. doi: 10.5935/abc.20170080. [Epub ahead of print] English, Portuguese. Erratum in: Arq Bras Cardiol. 2017 Aug 07;:0.


Utility of the MMPI-2 Restructured Form (MMPI-2-RF) in a sample of Lithuanian male offenders.

Laurinaitytė I, Laurinavičius A, Ustinavičiūtė L, Wygant DB, Sellbom M.

Law Hum Behav. 2017 Oct;41(5):494-505. doi: 10.1037/lhb0000254. Epub 2017 Jun 29.


Digital pathology imaging as a novel platform for standardization and globalization of quantitative nephropathology.

Barisoni L, Gimpel C, Kain R, Laurinavicius A, Bueno G, Zeng C, Liu Z, Schaefer F, Kretzler M, Holzman LB, Hewitt SM.

Clin Kidney J. 2017 Apr;10(2):176-187. doi: 10.1093/ckj/sfw129. Epub 2017 Feb 18.


IgA nephropathy clinicopathologic study following the Oxford classification: Progression peculiarities and gender-related differences.

Riispere Ž, Laurinavičius A, Kuudeberg A, Seppet E, Sepp K, Ilmoja M, Luman M, Kõlvald K, Auerbach A, Ots-Rosenberg M.

Medicina (Kaunas). 2016;52(6):340-348. doi: 10.1016/j.medici.2016.11.003. Epub 2016 Nov 22.


Extremely elevated HDL-cholesterol levels are not associated with increased carotid intima-media thickness: data from ELSA Brasil.

Laurinavicius AG, Santos IS, Santos RD, Bensenor IM, Conceição RD, Lotufo PA.

J Clin Lipidol. 2016 Jul-Aug;10(4):898-904.e1. doi: 10.1016/j.jacl.2016.03.007. Epub 2016 Mar 21.


Impact of tissue sampling on accuracy of Ki67 immunohistochemistry evaluation in breast cancer.

Besusparis J, Plancoulaine B, Rasmusson A, Augulis R, Green AR, Ellis IO, Laurinaviciene A, Herlin P, Laurinavicius A.

Diagn Pathol. 2016 Aug 30;11(1):82. doi: 10.1186/s13000-016-0525-z.


Comprehensive Immunohistochemistry: Digital, Analytical and Integrated.

Laurinavicius A, Plancoulaine B, Herlin P, Laurinaviciene A.

Pathobiology. 2016;83(2-3):156-63. doi: 10.1159/000442389. Epub 2016 Apr 26.


Skeletal Muscle-Derived Stem/Progenitor Cells: A Potential Strategy for the Treatment of Acute Kidney Injury.

Pavyde E, Maciulaitis R, Mauricas M, Sudzius G, Ivanauskaite Didziokiene E, Laurinavicius A, Sutkeviciene N, Stankevicius E, Maciulaitis J, Usas A.

Stem Cells Int. 2016;2016:9618480. doi: 10.1155/2016/9618480. Epub 2016 Mar 16.


Bimodality of intratumor Ki67 expression is an independent prognostic factor of overall survival in patients with invasive breast carcinoma.

Laurinavicius A, Plancoulaine B, Rasmusson A, Besusparis J, Augulis R, Meskauskas R, Herlin P, Laurinaviciene A, Abdelhadi Muftah AA, Miligy I, Aleskandarany M, Rakha EA, Green AR, Ellis IO.

Virchows Arch. 2016 Apr;468(4):493-502. doi: 10.1007/s00428-016-1907-z. Epub 2016 Jan 27.


Association between non-alcoholic hepatic steatosis and hyper reactive blood pressure response on the exercise treadmill test.

Laurinavicius AG, Bittencourt MS, Blaha MJ, Nary FC, Kashiwagi NM, Conceiçao RD, Meneghelo RS, Prado RR, Carvalho JA, Nasir K, Blumenthal RS, Santos RD.

QJM. 2016 Aug;109(8):531-7. doi: 10.1093/qjmed/hcw003. Epub 2016 Jan 19.


Ki67/SATB1 ratio is an independent prognostic factor of overall survival in patients with early hormone receptor-positive invasive ductal breast carcinoma.

Laurinavicius A, Green AR, Laurinaviciene A, Smailyte G, Ostapenko V, Meskauskas R, Ellis IO.

Oncotarget. 2015 Dec 1;6(38):41134-45. doi: 10.18632/oncotarget.5838.


A methodology for comprehensive breast cancer Ki67 labeling index with intra-tumor heterogeneity appraisal based on hexagonal tiling of digital image analysis data.

Plancoulaine B, Laurinaviciene A, Herlin P, Besusparis J, Meskauskas R, Baltrusaityte I, Iqbal Y, Laurinavicius A.

Virchows Arch. 2015 Oct 19. [Epub ahead of print]


Check-up and cardiovascular risk progression: is there a room for innovation?

Conceição RD, Laurinavicius AG, Kashiwagi NM, Carvalho JA, Oliva CA, Santos Filho RD.

Einstein (Sao Paulo). 2015 Apr-Jun;13(2):196-201. doi: 10.1590/S1679-45082015AO3216. English, Portuguese.


Preclinical study of SZ2080 material 3D microstructured scaffolds for cartilage tissue engineering made by femtosecond direct laser writing lithography.

Mačiulaitis J, Deveikytė M, Rekštytė S, Bratchikov M, Darinskas A, Šimbelytė A, Daunoras G, Laurinavičienė A, Laurinavičius A, Gudas R, Malinauskas M, Mačiulaitis R.

Biofabrication. 2015 Mar 23;7(1):015015. doi: 10.1088/1758-5090/7/1/015015.


Nationwide renal biopsy data in Lithuania 1994-2012.

Brazdziute E, Miglinas M, Gruodyte E, Priluckiene J, Tamosaitis A, Bumblyte IA, Kuzminskis V, Burbaickaja S, Sakalauskienė M, Jankauskienė A, Cerkauskiene R, Pundziene B, Laurinavicius A.

Int Urol Nephrol. 2015 Apr;47(4):655-62. doi: 10.1007/s11255-015-0927-y. Epub 2015 Feb 17.


Digital immunohistochemistry wizard: image analysis-assisted stereology tool to produce reference data set for calibration and quality control.

Plancoulaine B, Laurinaviciene A, Meskauskas R, Baltrusaityte I, Besusparis J, Herlin P, Laurinavicius A.

Diagn Pathol. 2014;9 Suppl 1:S8. doi: 10.1186/1746-1596-9-S1-S8. Epub 2014 Dec 19.


Digital immunohistochemistry platform for the staining variation monitoring based on integration of image and statistical analyses with laboratory information system.

Laurinaviciene A, Plancoulaine B, Baltrusaityte I, Meskauskas R, Besusparis J, Lesciute-Krilaviciene D, Raudeliunas D, Iqbal Y, Herlin P, Laurinavicius A.

Diagn Pathol. 2014;9 Suppl 1:S10. doi: 10.1186/1746-1596-9-S1-S10. Epub 2014 Dec 19.


Heterogeneity of DNA methylation in multifocal prostate cancer.

Serenaite I, Daniunaite K, Jankevicius F, Laurinavicius A, Petroska D, Lazutka JR, Jarmalaite S.

Virchows Arch. 2015 Jan;466(1):53-9. doi: 10.1007/s00428-014-1678-3. Epub 2014 Nov 5.


Quantitative histopathological assessment of ocular surface squamous neoplasia using digital image analysis.

Ašoklis R, Kadziauskienė A, Paulavičienė R, Petroška D, Laurinavičius A.

Oncol Lett. 2014 Oct;8(4):1482-1486. Epub 2014 Jul 22.


Calculated and perceived cardiovascular risk in asymptomatic subjects submitted to a routine medical evaluation: The perception gap.

Katz M, Laurinavicius AG, Franco FG, Conceicao RD, Carvalho JA, Pesaro AE, Wajngarten M, Santos RD.

Eur J Prev Cardiol. 2015 Aug;22(8):1076-82. doi: 10.1177/2047487314543074. Epub 2014 Jul 18.


Prognostic value of RASSF1 promoter methylation in prostate cancer.

Daniunaite K, Jarmalaite S, Kalinauskaite N, Petroska D, Laurinavicius A, Lazutka JR, Jankevicius F.

J Urol. 2014 Dec;192(6):1849-55. doi: 10.1016/j.juro.2014.06.075. Epub 2014 Jun 26.


Quantification of myocardial fibrosis by digital image analysis and interactive stereology.

Daunoravicius D, Besusparis J, Zurauskas E, Laurinaviciene A, Bironaite D, Pankuweit S, Plancoulaine B, Herlin P, Bogomolovas J, Grabauskiene V, Laurinavicius A.

Diagn Pathol. 2014 Jun 9;9:114. doi: 10.1186/1746-1596-9-114.


A methodology to ensure and improve accuracy of Ki67 labelling index estimation by automated digital image analysis in breast cancer tissue.

Laurinavicius A, Plancoulaine B, Laurinaviciene A, Herlin P, Meskauskas R, Baltrusaityte I, Besusparis J, Dasevicius D, Elie N, Iqbal Y, Bor C.

Breast Cancer Res. 2014;16(2):R35.


Relevance of prehypertension as a diagnostic category in asymptomatic adults.

Nary FC, Santos RD, Laurinavicius AG, Conceição RD, Carvalho JA.

Einstein (Sao Paulo). 2013 Jul-Sep;11(3):303-9. English, Portuguese.


Non-linear optical microscopy of kidney tumours.

Galli R, Sablinskas V, Dasevicius D, Laurinavicius A, Jankevicius F, Koch E, Steiner G.

J Biophotonics. 2014 Jan;7(1-2):23-7. doi: 10.1002/jbio.201200216. Epub 2013 Jan 31.


SNOMED CT in pathology.

García-Rojo M, Daniel C, Laurinavicius A.

Stud Health Technol Inform. 2012;179:123-40.


Standards and specifications in pathology: image management, report management and terminology.

Daniel C, Booker D, Beckwith B, Della Mea V, García-Rojo M, Havener L, Kennedy M, Klossa J, Laurinavicius A, Macary F, Punys V, Scharber W, Schrader T.

Stud Health Technol Inform. 2012;179:105-22.


Consequences of "going digital" for pathology professionals - entering the cloud.

Laurinavicius A, Raslavicus P.

Stud Health Technol Inform. 2012;179:62-7. Review.


The effect of response style on self-reported Conscientiousness across 20 countries.

Mõttus R, Allik J, Realo A, Rossier J, Zecca G, Ah-Kion J, Amoussou-Yéyé D, Bäckström M, Barkauskiene R, Barry O, Bhowon U, Björklund F, Bochaver A, Bochaver K, de Bruin G, Cabrera HF, Chen SX, Church AT, Cissé DD, Dahourou D, Feng X, Guan Y, Hwang HS, Idris F, Katigbak MS, Kuppens P, Kwiatkowska A, Laurinavicius A, Mastor KA, Matsumoto D, Riemann R, Schug J, Simpson B, Tseung-Wong CN, Johnson W.

Pers Soc Psychol Bull. 2012 Nov;38(11):1423-36. doi: 10.1177/0146167212451275. Epub 2012 Jun 27.


Epigenetic markers of prostate cancer in plasma circulating DNA.

Cortese R, Kwan A, Lalonde E, Bryzgunova O, Bondar A, Wu Y, Gordevicius J, Park M, Oh G, Kaminsky Z, Tverkuviene J, Laurinavicius A, Jankevicius F, Sendorek DH, Haider S, Wang SC, Jarmalaite S, Laktionov P, Boutros PC, Petronis A.

Hum Mol Genet. 2012 Aug 15;21(16):3619-31. doi: 10.1093/hmg/dds192. Epub 2012 May 22.


Unilateral hydronephrosis and renal damage after acute leukemia.

Simanauskiene E, Daugelaviciene V, Laurinavicius A, Mickys U, Simonyte V, Vaitkeviciene G, Verkauskas G.

Case Rep Med. 2012;2012:968491. doi: 10.1155/2012/968491. Epub 2012 Apr 3.


Combined analysis of TMPRSS2-ERG and TERT for improved prognosis of biochemical recurrence in prostate cancer.

Sabaliauskaite R, Jarmalaite S, Petroska D, Dasevicius D, Laurinavicius A, Jankevicius F, Lazutka JR.

Genes Chromosomes Cancer. 2012 Aug;51(8):781-91. doi: 10.1002/gcc.21963. Epub 2012 Apr 16.


Immunohistochemistry profiles of breast ductal carcinoma: factor analysis of digital image analysis data.

Laurinavicius A, Laurinaviciene A, Ostapenko V, Dasevicius D, Jarmalaite S, Lazutka J.

Diagn Pathol. 2012 Mar 16;7:27. doi: 10.1186/1746-1596-7-27.


The First Congress of the International Academy of Digital Pathology: digital pathology comes of age.

Yagi Y, Rojo MG, Kayser K, Kayser G, Laurinavicius A, Della Mea V, Levy B, Klossa J, Tearney G, Szymas J, Tsuchihashi Y, Têtu B.

Anal Cell Pathol (Amst). 2012;35(1):1-2. doi: 10.3233/ACP-2011-0049. No abstract available.


Digital image analysis in pathology: benefits and obligation.

Laurinavicius A, Laurinaviciene A, Dasevicius D, Elie N, Plancoulaine B, Bor C, Herlin P.

Anal Cell Pathol (Amst). 2012;35(2):75-8. doi: 10.3233/ACP-2011-0033. Review.


Infrared spectroscopic imaging of renal tumor tissue.

Sablinskas V, Urboniene V, Ceponkus J, Laurinavicius A, Dasevicius D, Jankevicius F, Hendrixson V, Koch E, Steiner G.

J Biomed Opt. 2011 Sep;16(9):096006. doi: 10.1117/1.3622292.


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