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Items: 1 to 50 of 82

1.

Transcription Factor USF1 Is Required for Maintenance of Germline Stem Cells in Male Mice.

Faisal I, Cisneros-Montalvo S, Hamer G, Tuominen MM, Laurila PP, Tumiati M, Jauhiainen M, Kotaja N, Toppari J, Mäkelä JA, Kauppi L.

Endocrinology. 2019 May 1;160(5):1119-1136. doi: 10.1210/en.2018-01088.

PMID:
30759202
2.

Swallowing-related quality of life after free flap surgery due to cancer of the head and neck.

Lahtinen S, Koivunen P, Ala-Kokko T, Kaarela O, Laurila P, Liisanantti JH.

Eur Arch Otorhinolaryngol. 2019 Mar;276(3):821-826. doi: 10.1007/s00405-018-05264-w. Epub 2018 Dec 28.

3.

Short- and long-term mortality and causes of death after reconstruction of cancers of the head and neck with free flaps.

Lahtinen S, Koivunen P, Ala-Kokko T, Kaarela O, Ohtonen P, Laurila P, Liisanantti JH.

Br J Oral Maxillofac Surg. 2019 Jan;57(1):21-28. doi: 10.1016/j.bjoms.2018.12.004. Epub 2018 Dec 21.

PMID:
30583873
4.

USF1 deficiency alleviates inflammation, enhances cholesterol efflux and prevents cholesterol accumulation in macrophages.

Ruuth M, Soronen J, Kaiharju E, Merikanto K, Perttilä J, Metso J, Lee-Rueckert M, Taskinen MR, Kovanen PT, Öörni K, Olkkonen VM, Jauhiainen MS, Laurila PP.

Lipids Health Dis. 2018 Dec 13;17(1):285. doi: 10.1186/s12944-018-0930-2.

5.

Quality of life after free flap surgery for cancer of the head and neck in patients with or without postoperative complications.

Lahtinen S, Koivunen P, Ala-Kokko T, Laurila P, Kaarela O, Liisanantti JH.

Eur Arch Otorhinolaryngol. 2018 Oct;275(10):2575-2584. doi: 10.1007/s00405-018-5103-4. Epub 2018 Aug 24.

PMID:
30143854
6.

Complications and outcome after free flap surgery for cancer of the head and neck.

Lahtinen S, Koivunen P, Ala-Kokko T, Kaarela O, Ohtonen P, Laurila P, Liisanantti JH.

Br J Oral Maxillofac Surg. 2018 Oct;56(8):684-691. doi: 10.1016/j.bjoms.2018.07.009. Epub 2018 Aug 11.

PMID:
30107953
7.

Thromboelastography Values Remain Hypercoagulative 6 Months After Obesity Surgery: a Pilot Study.

Tuovila M, Erkinaro T, Koivukangas V, Savolainen ER, Laurila P, Ohtonen P, Ala-Kokko T.

Obes Surg. 2018 Dec;28(12):3943-3949. doi: 10.1007/s11695-018-3437-z.

PMID:
30083792
8.

Testing for high-risk HPV in cervical and tonsillar paraffin-embedded tissue using a cartridge-based assay.

Virtanen E, Laurila P, Hagström J, Nieminen P, Auvinen E.

APMIS. 2017 Oct;125(10):910-915. doi: 10.1111/apm.12727. Epub 2017 Jul 24.

PMID:
28736821
9.

The impact of sample site and storage on thromboelastography values.

Tuovila M, Erkinaro T, Savolainen ER, Laurila P, Ohtonen P, Ala-Kokko T.

Am J Hematol. 2017 Aug;92(8):E160-E162. doi: 10.1002/ajh.24766. Epub 2017 Jun 1. No abstract available.

10.

Goal-directed fluid management in free flap surgery for cancer of the head and neck.

Lahtinen SL, Liisanantti JH, Poukkanen MM, Laurila PA.

Minerva Anestesiol. 2017 Jan;83(1):59-68. doi: 10.23736/S0375-9393.16.11451-8. Epub 2016 Oct 19.

11.

The Contribution of GWAS Loci in Familial Dyslipidemias.

Ripatti P, Rämö JT, Söderlund S, Surakka I, Matikainen N, Pirinen M, Pajukanta P, Sarin AP, Service SK, Laurila PP, Ehnholm C, Salomaa V, Wilson RK, Palotie A, Freimer NB, Taskinen MR, Ripatti S.

PLoS Genet. 2016 May 26;12(5):e1006078. doi: 10.1371/journal.pgen.1006078. eCollection 2016 May.

12.

USF1 deficiency activates brown adipose tissue and improves cardiometabolic health.

Laurila PP, Soronen J, Kooijman S, Forsström S, Boon MR, Surakka I, Kaiharju E, Coomans CP, Van Den Berg SA, Autio A, Sarin AP, Kettunen J, Tikkanen E, Manninen T, Metso J, Silvennoinen R, Merikanto K, Ruuth M, Perttilä J, Mäkelä A, Isomi A, Tuomainen AM, Tikka A, Ramadan UA, Seppälä I, Lehtimäki T, Eriksson J, Havulinna A, Jula A, Karhunen PJ, Salomaa V, Perola M, Ehnholm C, Lee-Rueckert M, Van Eck M, Roivainen A, Taskinen MR, Peltonen L, Mervaala E, Jalanko A, Hohtola E, Olkkonen VM, Ripatti S, Kovanen PT, Rensen PC, Suomalainen A, Jauhiainen M.

Sci Transl Med. 2016 Jan 27;8(323):323ra13. doi: 10.1126/scitranslmed.aad0015.

PMID:
26819196
13.

Novel hepatic microRNAs upregulated in human nonalcoholic fatty liver disease.

Soronen J, Yki-Järvinen H, Zhou Y, Sädevirta S, Sarin AP, Leivonen M, Sevastianova K, Perttilä J, Laurila PP, Sigruener A, Schmitz G, Olkkonen VM.

Physiol Rep. 2016 Jan;4(1). pii: e12661. doi: 10.14814/phy2.12661.

14.
15.

Enhanced vascular permeability facilitates entry of plasma HDL and promotes macrophage-reverse cholesterol transport from skin in mice.

Kareinen I, Cedó L, Silvennoinen R, Laurila PP, Jauhiainen M, Julve J, Blanco-Vaca F, Escola-Gil JC, Kovanen PT, Lee-Rueckert M.

J Lipid Res. 2015 Feb;56(2):241-53. doi: 10.1194/jlr.M050948. Epub 2014 Dec 3.

16.

Osbpl8 deficiency in mouse causes an elevation of high-density lipoproteins and gender-specific alterations of lipid metabolism.

Béaslas O, Metso J, Nissilä E, Laurila PP, Kaiharju E, Batchu KC, Kaipiainen L, Mäyränpää MI, Yan D, Gylling H, Jauhiainen M, Olkkonen VM.

PLoS One. 2013;8(3):e58856. doi: 10.1371/journal.pone.0058856. Epub 2013 Mar 15.

17.

Genomic, transcriptomic, and lipidomic profiling highlights the role of inflammation in individuals with low high-density lipoprotein cholesterol.

Laurila PP, Surakka I, Sarin AP, Yetukuri L, Hyötyläinen T, Söderlund S, Naukkarinen J, Tang J, Kettunen J, Mirel DB, Soronen J, Lehtimäki T, Ruokonen A, Ehnholm C, Eriksson JG, Salomaa V, Jula A, Raitakari OT, Järvelin MR, Palotie A, Peltonen L, Oresic M, Jauhiainen M, Taskinen MR, Ripatti S.

Arterioscler Thromb Vasc Biol. 2013 Apr;33(4):847-57. doi: 10.1161/ATVBAHA.112.300733. Epub 2013 Feb 14.

PMID:
23413431
18.

Detection rates of precancerous and cancerous cervical lesions within one screening round of primary human papillomavirus DNA testing: prospective randomised trial in Finland.

Leinonen MK, Nieminen P, Lönnberg S, Malila N, Hakama M, Pokhrel A, Laurila P, Tarkkanen J, Anttila A.

BMJ. 2012 Nov 29;345:e7789. doi: 10.1136/bmj.e7789.

19.

The HPV test has similar sensitivity but more overdiagnosis than the Pap test--a randomised health services study on cervical cancer screening in Finland.

Malila N, Leinonen M, Kotaniemi-Talonen L, Laurila P, Tarkkanen J, Hakama M.

Int J Cancer. 2013 May 1;132(9):2141-7. doi: 10.1002/ijc.27850. Epub 2012 Oct 12.

20.

Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.

Inouye M, Ripatti S, Kettunen J, Lyytikäinen LP, Oksala N, Laurila PP, Kangas AJ, Soininen P, Savolainen MJ, Viikari J, Kähönen M, Perola M, Salomaa V, Raitakari O, Lehtimäki T, Taskinen MR, Järvelin MR, Ala-Korpela M, Palotie A, de Bakker PI.

PLoS Genet. 2012;8(8):e1002907. doi: 10.1371/journal.pgen.1002907. Epub 2012 Aug 16.

21.
22.

A randomised controlled trial comparing sugammadex and neostigmine at different depths of neuromuscular blockade in patients undergoing laparoscopic surgery.

Geldner G, Niskanen M, Laurila P, Mizikov V, Hübler M, Beck G, Rietbergen H, Nicolayenko E.

Anaesthesia. 2012 Sep;67(9):991-8. doi: 10.1111/j.1365-2044.2012.07197.x. Epub 2012 Jun 14.

23.

Silencing of OSBP-related protein 8 (ORP8) modifies the macrophage transcriptome, nucleoporin p62 distribution, and migration capacity.

Béaslas O, Vihervaara T, Li J, Laurila PP, Yan D, Olkkonen VM.

Exp Cell Res. 2012 Sep 10;318(15):1933-45. doi: 10.1016/j.yexcr.2012.05.026. Epub 2012 Jun 5.

PMID:
22683860
24.

Adipose tissue gene expression analysis reveals changes in inflammatory, mitochondrial respiratory and lipid metabolic pathways in obese insulin-resistant subjects.

Soronen J, Laurila PP, Naukkarinen J, Surakka I, Ripatti S, Jauhiainen M, Olkkonen VM, Yki-Järvinen H.

BMC Med Genomics. 2012 Apr 3;5:9. doi: 10.1186/1755-8794-5-9.

25.

A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol.

Surakka I, Isaacs A, Karssen LC, Laurila PP, Middelberg RP, Tikkanen E, Ried JS, Lamina C, Mangino M, Igl W, Hottenga JJ, Lagou V, van der Harst P, Mateo Leach I, Esko T, Kutalik Z, Wainwright NW, Struchalin MV, Sarin AP, Kangas AJ, Viikari JS, Perola M, Rantanen T, Petersen AK, Soininen P, Johansson A, Soranzo N, Heath AC, Papamarkou T, Prokopenko I, Tönjes A, Kronenberg F, Döring A, Rivadeneira F, Montgomery GW, Whitfield JB, Kähönen M, Lehtimäki T, Freimer NB, Willemsen G, de Geus EJ, Palotie A, Sandhu MS, Waterworth DM, Metspalu A, Stumvoll M, Uitterlinden AG, Jula A, Navis G, Wijmenga C, Wolffenbuttel BH, Taskinen MR, Ala-Korpela M, Kaprio J, Kyvik KO, Boomsma DI, Pedersen NL, Gyllensten U, Wilson JF, Rudan I, Campbell H, Pramstaller PP, Spector TD, Witteman JC, Eriksson JG, Salomaa V, Oostra BA, Raitakari OT, Wichmann HE, Gieger C, Järvelin MR, Martin NG, Hofman A, McCarthy MI, Peltonen L, van Duijn CM, Aulchenko YS, Ripatti S; ENGAGE Consortium.

PLoS Genet. 2011 Oct;7(10):e1002333. doi: 10.1371/journal.pgen.1002333. Epub 2011 Oct 20.

26.

The duration of residual neuromuscular block after administration of neostigmine or sugammadex at two visible twitches during train-of-four monitoring.

Illman HL, Laurila P, Antila H, Meretoja OA, Alahuhta S, Olkkola KT.

Anesth Analg. 2011 Jan;112(1):63-8. doi: 10.1213/ANE.0b013e3181fdf889. Epub 2010 Oct 26.

PMID:
20978247
27.

Rate of cervical cancer, severe intraepithelial neoplasia, and adenocarcinoma in situ in primary HPV DNA screening with cytology triage: randomised study within organised screening programme.

Anttila A, Kotaniemi-Talonen L, Leinonen M, Hakama M, Laurila P, Tarkkanen J, Malila N, Nieminen P.

BMJ. 2010 Apr 27;340:c1804. doi: 10.1136/bmj.c1804.

28.

Genetic association and interaction analysis of USF1 and APOA5 on lipid levels and atherosclerosis.

Laurila PP, Naukkarinen J, Kristiansson K, Ripatti S, Kauttu T, Silander K, Salomaa V, Perola M, Karhunen PJ, Barter PJ, Ehnholm C, Peltonen L.

Arterioscler Thromb Vasc Biol. 2010 Feb;30(2):346-52. doi: 10.1161/ATVBAHA.109.188912. Epub 2009 Nov 12.

29.

Age-specific evaluation of primary human papillomavirus screening vs conventional cytology in a randomized setting.

Leinonen M, Nieminen P, Kotaniemi-Talonen L, Malila N, Tarkkanen J, Laurila P, Anttila A.

J Natl Cancer Inst. 2009 Dec 2;101(23):1612-23. doi: 10.1093/jnci/djp367. Epub 2009 Nov 9.

PMID:
19903804
30.

Bone attachment to glass-fibre-reinforced composite implant with porous surface.

Mattila RH, Laurila P, Rekola J, Gunn J, Lassila LV, Mäntylä T, Aho AJ, Vallittu PK.

Acta Biomater. 2009 Jun;5(5):1639-46. doi: 10.1016/j.actbio.2009.01.020. Epub 2009 Jan 29.

PMID:
19268643
31.

Development of a multi-component fiber-reinforced composite implant for load-sharing conditions.

Zhao DS, Moritz N, Laurila P, Mattila R, Lassila LV, Strandberg N, Mäntylä T, Vallittu PK, Aro HT.

Med Eng Phys. 2009 May;31(4):461-9. doi: 10.1016/j.medengphy.2008.11.006. Epub 2008 Dec 23.

PMID:
19109047
32.

Test positivity cutoff level of a high risk human papillomavirus test could be increased in routine cervical cancer screening.

Kotaniemi-Talonen L, Malila N, Nieminen P, Anttila A, Tarkkanen J, Laurila P, Hakama M.

Int J Cancer. 2008 Dec 15;123(12):2902-6. doi: 10.1002/ijc.23839.

33.

Screening with a primary human papillomavirus test does not increase detection of cervical cancer and intraepithelial neoplasia 3.

Kotaniemi-Talonen L, Anttila A, Malila N, Tarkkanen J, Laurila P, Hakama M, Nieminen P.

Eur J Cancer. 2008 Mar;44(4):565-71. doi: 10.1016/j.ejca.2007.12.002. Epub 2008 Jan 8.

PMID:
18248809
34.

Effects of pH management during selective antegrade cerebral perfusion on cerebral microcirculation and metabolism: alpha-stat versus pH-stat.

Dahlbacka S, Alaoja H, Mäkelä J, Niemelä E, Laurila P, Kiviluoma K, Honkanen A, Ohtonen P, Anttila V, Juvonen T.

Ann Thorac Surg. 2007 Sep;84(3):847-55.

PMID:
17720388
35.

HPV DNA testing as an adjunct in the management of patients with low grade cytological lesions in Finland.

Tarkkanen J, Auvinen E, Nieminen P, Malmi R, Vartiainen J, Timonen T, Laurila P, Räisänen I, Unnerus HA, Sakki A, Mattila P, Van Den Brule AV, Tapper AM.

Acta Obstet Gynecol Scand. 2007;86(3):367-72.

PMID:
17364315
36.

Tight junction proteins in gallbladder epithelium: different expression in acute acalculous and calculous cholecystitis.

Laurila JJ, Karttunen T, Koivukangas V, Laurila PA, Syrjälä H, Saarnio J, Soini Y, Ala-Kokko TI.

J Histochem Cytochem. 2007 Jun;55(6):567-73. Epub 2007 Feb 5.

PMID:
17283368
37.

Leukocyte filtration to decrease the number of adherent leukocytes in the cerebral microcirculation after a period of deep hypothermic circulatory arrest.

Alaoja H, Niemelä E, Anttila V, Dahlbacka S, Mäkelä J, Kiviluoma K, Laurila P, Kaakinen T, Juvonen T.

J Thorac Cardiovasc Surg. 2006 Dec;132(6):1339-47.

38.

Incidence of infections in patients with status epilepticus requiring intensive care and effect on resource utilization.

Ala-Kokko TI, Säynäjäkangas P, Laurila P, Ohtonen P, Laurila JJ, Syrjälä H.

Anaesth Intensive Care. 2006 Oct;34(5):639-44.

39.

Fructose-1,6-bisphosphate supports cerebral energy metabolism in pigs after ischemic brain injury caused by experimental particle embolization.

Kaakinen T, Heikkinen J, Dahlbacka S, Alaoja H, Laurila P, Kiviluoma K, Salomäki T, Romsi P, Tuominen H, Biancari F, Lepola P, Nuutinen M, Juvonen T.

Heart Surg Forum. 2006;9(6):E828-35.

PMID:
16893758
40.

Aprotinin to improve cerebral outcome after hypothermic circulatory arrest: a study in a surviving porcine model.

Heikkinen J, Kaakinen T, Dahlbacka S, Kiviluoma K, Salomäki T, Laurila P, Biancari F, Tuominen H, Anttila V, Juvonen T.

Heart Surg Forum. 2006;9(4):E719-24.

PMID:
16844627
41.

Propofol is associated with impaired brain metabolism during hypothermic circulatory arrest: an experimental microdialysis study.

Dahlbacka S, Mäkelä J, Kaakinen T, Alaoja H, Heikkinen J, Laurila P, Kiviluoma K, Salomäki T, Tuominen H, Ohtonen P, Lepola P, Biancari F, Juvonen T.

Heart Surg Forum. 2006;9(4):E710-8; discussion E718.

PMID:
16844626
42.

Organ system dysfunction following open cholecystectomy for acute acalculous cholecystitis in critically ill patients.

Laurila J, Laurila PA, Saarnio J, Koivukangas V, Syrjälä H, Ala-Kokko TI.

Acta Anaesthesiol Scand. 2006 Feb;50(2):173-9.

PMID:
16430538
43.

Hypertonic saline dextran improves outcome after hypothermic circulatory arrest: a study in a surviving porcine model.

Kaakinen T, Alaoja H, Heikkinen J, Dahlbacka S, Laurila P, Kiviluoma K, Salomäki T, Tuominen H, Ohtonen P, Biancari F, Juvonen T.

Ann Thorac Surg. 2006 Jan;81(1):183-90.

PMID:
16368360
44.

Successful resuscitation after cardiovascular collapse following accidental intravenous infusion of levobupivacaine during general anesthesia.

Salomäki TE, Laurila PA, Ville J.

Anesthesiology. 2005 Nov;103(5):1095-6. No abstract available.

PMID:
16249685
45.

Histopathology of acute acalculous cholecystitis in critically ill patients.

Laurila JJ, Ala-Kokko TI, Laurila PA, Saarnio J, Koivukangas V, Syrjälä H, Karttunen TJ.

Histopathology. 2005 Nov;47(5):485-92.

PMID:
16241996
46.

pH-stat versus alpha-stat acid-base management strategy during hypothermic circulatory arrest combined with embolic brain injury.

Dahlbacka S, Heikkinen J, Kaakinen T, Laurila P, Vainionpää V, Kiviluoma K, Salomäki T, Tuominen H, Ohtonen P, Biancari F, Lepola P, Juvonen T.

Ann Thorac Surg. 2005 Apr;79(4):1316-25.

PMID:
15797070
47.

Acute acalculous cholecystitis in critically ill patients.

Laurila J, Syrjälä H, Laurila PA, Saarnio J, Ala-Kokko TI.

Acta Anaesthesiol Scand. 2004 Sep;48(8):986-91.

PMID:
15315616
48.

Apotransferrin, C1-esterase inhibitor, and alpha 1-acid glycoprotein for cerebral protection during experimental hypothermic circulatory arrest.

Heikkinen J, Koskenkari J, Kaakinen T, Dahlbacka S, Kiviluoma K, Salomäki T, Laurila P, Hirvonen J, Biancari F, Parkkinen J, Juvonen T.

Scand Cardiovasc J. 2004 Jun;38(3):178-86.

PMID:
15223717
49.

Interscalene brachial plexus block is superior to subacromial bursa block after arthroscopic shoulder surgery.

Laurila PA, Löppönen A, Kanga-Saarela T, Flinkkilä T, Salomäki TE.

Acta Anaesthesiol Scand. 2002 Sep;46(8):1031-6.

PMID:
12190808
50.

The adhesion molecule CD44v6 is associated with a high risk for local recurrence in adult soft tissue sarcomas.

Maula S, Huuhtanen RL, Blomqvist CP, Wiklund TA, Laurila P, Ristamäki R.

Br J Cancer. 2001 Jan;84(2):244-52.

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