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Items: 12

1.

Selective RET kinase inhibition for patients with RET-altered cancers.

Subbiah V, Velcheti V, Tuch BB, Ebata K, Busaidy NL, Cabanillas ME, Wirth LJ, Stock S, Smith S, Lauriault V, Corsi-Travali S, Henry D, Burkard M, Hamor R, Bouhana K, Winski S, Wallace RD, Hartley D, Rhodes S, Reddy M, Brandhuber BJ, Andrews S, Rothenberg SM, Drilon A.

Ann Oncol. 2018 Aug 1;29(8):1869-1876. doi: 10.1093/annonc/mdy137.

2.

A Next-Generation TRK Kinase Inhibitor Overcomes Acquired Resistance to Prior TRK Kinase Inhibition in Patients with TRK Fusion-Positive Solid Tumors.

Drilon A, Nagasubramanian R, Blake JF, Ku N, Tuch BB, Ebata K, Smith S, Lauriault V, Kolakowski GR, Brandhuber BJ, Larsen PD, Bouhana KS, Winski SL, Hamor R, Wu WI, Parker A, Morales TH, Sullivan FX, DeWolf WE, Wollenberg LA, Gordon PR, Douglas-Lindsay DN, Scaltriti M, Benayed R, Raj S, Hanusch B, Schram AM, Jonsson P, Berger MF, Hechtman JF, Taylor BS, Andrews S, Rothenberg SM, Hyman DM.

Cancer Discov. 2017 Sep;7(9):963-972. doi: 10.1158/2159-8290.CD-17-0507. Epub 2017 Jun 3.

3.

Antibody-mediated inhibition of fibroblast growth factor 19 results in increased bile acids synthesis and ileal malabsorption of bile acids in cynomolgus monkeys.

Pai R, French D, Ma N, Hotzel K, Plise E, Salphati L, Setchell KD, Ware J, Lauriault V, Schutt L, Hartley D, Dambach D.

Toxicol Sci. 2012 Apr;126(2):446-56. doi: 10.1093/toxsci/kfs011. Epub 2012 Jan 19.

PMID:
22268002
4.
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7.

The antidotal activity of the thiol drug diethyldithiocarbamate against N-acetyl-p-benzoquinone imine in isolated hepatocytes.

Lauriault VV, O'Brien PJ.

Adv Exp Med Biol. 1991;283:311-4. No abstract available.

PMID:
1648865
8.
9.

Modulation of benzoquinone-induced cytotoxicity by diethyldithiocarbamate in isolated hepatocytes.

Lauriault VV, McGirr LG, Wong WW, O'Brien PJ.

Arch Biochem Biophys. 1990 Oct;282(1):26-33.

PMID:
2171431
10.

Molecular mechanisms for bromotrichloromethane cytotoxicity in isolated rat hepatocytes.

McGirr LG, Khan S, Lauriault V, O'Brien PJ.

Xenobiotica. 1990 Sep;20(9):933-43.

PMID:
2238712
11.
12.

The toxicity of disulphides to isolated hepatocytes and mitochondria.

Jatoe SD, Lauriault V, McGirr LG, O'Brien PJ.

Drug Metabol Drug Interact. 1988;6(3-4):395-412.

PMID:
3155362

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