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Items: 1 to 50 of 382

1.

Health outcomes, utility and costs of returning incidental results from genomic sequencing in a Canadian cancer population: protocol for a mixed-methods randomised controlled trial.

Shickh S, Clausen M, Mighton C, Gutierrez Salazar M, Zakoor KR, Kodida R, Reble E, Elser C, Eisen A, Panchal S, Aronson M, Graham T, Armel SR, Morel CF, Fattouh R, Glogowski E, Schrader KA, Hamilton JG, Offit K, Robson M, Carroll JC, Isaranuwatchai W, Kim RH, Lerner-Ellis J, Thorpe KE, Laupacis A, Bombard Y; Incidental Genomics Study Team.

BMJ Open. 2019 Oct 7;9(10):e031092. doi: 10.1136/bmjopen-2019-031092.

2.

Effect on Treatment Adherence of Distributing Essential Medicines at No Charge: The CLEAN Meds Randomized Clinical Trial.

Persaud N, Bedard M, Boozary AS, Glazier RH, Gomes T, Hwang SW, Jüni P, Law MR, Mamdani MM, Manns BJ, Martin D, Morgan SG, Oh PI, Pinto AD, Shah BR, Sullivan F, Umali N, Thorpe KE, Tu K, Laupacis A; Carefully Selected and Easily Accessible at No Charge Medicines (CLEAN Meds) Study Team.

JAMA Intern Med. 2019 Oct 7. doi: 10.1001/jamainternmed.2019.4472. [Epub ahead of print]

PMID:
31589276
3.

Engaging Patients and Caregivers in Research for Pediatric Inflammatory Bowel Disease: Top 10 Research Priorities.

Grant A, Crane M, Laupacis A, Griffiths A, Burnett D, Hood A, Kluthe C, Maghera M, Mann M, Mansi M, Murray K, Trempe MJ, Otley A.

J Pediatr Gastroenterol Nutr. 2019 Sep;69(3):317-323. doi: 10.1097/MPG.0000000000002396.

PMID:
31436670
4.

Where do goals of care conversations belong? A case for the emergency department.

Cameron B, Laupacis A.

CJEM. 2019 Jul 22:1-3. doi: 10.1017/cem.2019.364. [Epub ahead of print] No abstract available.

PMID:
31327326
5.

Association of preoperative anaemia with cardiopulmonary exercise capacity and postoperative outcomes in noncardiac surgery: a substudy of the Measurement of Exercise Tolerance before Surgery (METS) Study.

Bartoszko J, Thorpe KE, Laupacis A, Wijeysundera DN; METS Study Investigators; International and National Coordinators; Central Project Office Operations Committee; CPET Methods Committee; Outcome Adjudication Committee; International Steering Committee.

Br J Anaesth. 2019 Aug;123(2):161-169. doi: 10.1016/j.bja.2019.04.058. Epub 2019 Jun 19.

6.

Engaging Patients and Caregivers in Research for Pediatric IBD: Top 10 Research Priorities.

Grant A, Crane M, Laupacis A, Griffiths A, Burnett D, Hood A, Kluthe C, Maghera M, Mann M, Mansi M, Murray K, Trempe MJ, Otley A.

J Pediatr Gastroenterol Nutr. 2019 May 18. doi: 10.1097/MPG.0000000000002396. [Epub ahead of print]

PMID:
31124889
7.

Temporal Trends of Women Enrollment in Major Cardiovascular Randomized Clinical Trials.

Gong IY, Tan NS, Ali SH, Lebovic G, Mamdani M, Goodman SG, Ko DT, Laupacis A, Yan AT.

Can J Cardiol. 2019 May;35(5):653-660. doi: 10.1016/j.cjca.2019.01.010. Epub 2019 Jan 30.

PMID:
31030866
8.

Trends in site of death and health care utilization at the end of life: a population-based cohort study.

Hill AD, Stukel TA, Fu L, Scales DC, Laupacis A, Rubenfeld GD, Wunsch H, Downar J, Rockwood K, Heyland DK, Sinha SK, Zimmermann C, Gandhi S, Myers J, Ross HJ, Kozak JF, Berry S, Dev SP, La Delfa I, Fowler RA.

CMAJ Open. 2019 Apr 26;7(2):E306-E315. doi: 10.9778/cmajo.20180097. Print 2019 Apr-Jun.

9.

Association of the Trauma of Hospitalization With 30-Day Readmission or Emergency Department Visit.

Rawal S, Kwan JL, Razak F, Detsky AS, Guo Y, Lapointe-Shaw L, Tang T, Weinerman A, Laupacis A, Subramanian SV, Verma AA.

JAMA Intern Med. 2019 Jan 1;179(1):38-45. doi: 10.1001/jamainternmed.2018.5100.

PMID:
30508018
10.

Effect of High-Dose Vitamin D Supplementation on Upper Respiratory Tract Infection Symptom Severity in Healthy Children.

Hueniken K, Aglipay M, Birken CS, Parkin PC, Loeb MB, Thorpe KE, Dai DWH, Laupacis A, Mamdani M, Mazzulli T, Maguire JL; TARGet Kids! Collaboration.

Pediatr Infect Dis J. 2019 Jun;38(6):564-568. doi: 10.1097/INF.0000000000002225.

PMID:
30399024
11.

Perceived Significance of Engagement in Research Prioritization Among Chronic Kidney Disease Patients, Caregivers, and Health Care Professionals: A Qualitative Study.

Elliott MJ, Goodarzi Z, Sale JEM, Wilhelm LA, Laupacis A, Hemmelgarn BR, Straus SE.

Can J Kidney Health Dis. 2018 Oct 19;5:2054358118807480. doi: 10.1177/2054358118807480. eCollection 2018.

12.

Long-term views on chronic kidney disease research priorities among stakeholders engaged in a priority-setting partnership: A qualitative study.

Elliott MJ, Sale JEM, Goodarzi Z, Wilhelm L, Laupacis A, Hemmelgarn BR, Straus SE.

Health Expect. 2018 Dec;21(6):1142-1149. doi: 10.1111/hex.12818. Epub 2018 Aug 15.

13.

Patient and Public Involvement in Identifying Dementia Research Priorities.

Bethell J, Pringle D, Chambers LW, Cohen C, Commisso E, Cowan K, Fehr P, Laupacis A, Szeto P, McGilton KS.

J Am Geriatr Soc. 2018 Aug;66(8):1608-1612. doi: 10.1111/jgs.15453. Epub 2018 Aug 7.

PMID:
30084194
14.

Xylitol for the prevention of acute otitis media episodes in children aged 2-4 years: protocol for a pragmatic randomised controlled trial.

Persaud N, Laupacis A, Azarpazhooh A, Birken C, Hoch JS, Isaranuwatchai W, Maguire JL, Mamdani MM, Thorpe K, Allen C, Mason D, Kowal C, Bazeghi F, Parkin P; TARGet Kids! Collaboration.

BMJ Open. 2018 Aug 5;8(8):e020941. doi: 10.1136/bmjopen-2017-020941.

15.

Intensive care utilization following major noncardiac surgical procedures in Ontario, Canada: a population-based study.

Jerath A, Laupacis A, Austin PC, Wunsch H, Wijeysundera DN.

Intensive Care Med. 2018 Sep;44(9):1427-1435. doi: 10.1007/s00134-018-5330-6. Epub 2018 Jul 27.

PMID:
30054691
16.

Emerging Trends in Clinical Research: With Implications for Population Health and Health Policy.

Chin-Yee B, Subramanian SV, Verma AA, Laupacis A, Razak F.

Milbank Q. 2018 Jun;96(2):369-401. doi: 10.1111/1468-0009.12328.

17.

Should thoracic paravertebral blocks be used to prevent chronic postsurgical pain after breast cancer surgery? A systematic analysis of evidence in light of IMMPACT recommendations.

Hussain N, Shastri U, McCartney CJL, Gilron I, Fillingim RB, Clarke H, Katz J, Juni P, Laupacis A, Wijeysundera D, Abdallah FW.

Pain. 2018 Oct;159(10):1955-1971. doi: 10.1097/j.pain.0000000000001292.

PMID:
29794879
18.

The Genomics ADvISER: development and usability testing of a decision aid for the selection of incidental sequencing results.

Bombard Y, Clausen M, Mighton C, Carlsson L, Casalino S, Glogowski E, Schrader K, Evans M, Scheer A, Baxter N, Hamilton JG, Lerner-Ellis J, Offit K, Robson M, Laupacis A.

Eur J Hum Genet. 2018 Jul;26(7):984-995. doi: 10.1038/s41431-018-0144-0. Epub 2018 Apr 27.

19.

Evaluation of a decision aid for incidental genomic results, the Genomics ADvISER: protocol for a mixed methods randomised controlled trial.

Shickh S, Clausen M, Mighton C, Casalino S, Joshi E, Glogowski E, Schrader KA, Scheer A, Elser C, Panchal S, Eisen A, Graham T, Aronson M, Semotiuk KM, Winter-Paquette L, Evans M, Lerner-Ellis J, Carroll JC, Hamilton JG, Offit K, Robson M, Thorpe KE, Laupacis A, Bombard Y.

BMJ Open. 2018 Apr 26;8(4):e021876. doi: 10.1136/bmjopen-2018-021876.

20.

Laying the digital and analytical foundations for Canada's future health care system.

Mamdani M, Laupacis A.

CMAJ. 2018 Jan 8;190(1):E1-E2. doi: 10.1503/cmaj.170955. No abstract available.

21.

Patient characteristics, resource use and outcomes associated with general internal medicine hospital care: the General Medicine Inpatient Initiative (GEMINI) retrospective cohort study.

Verma AA, Guo Y, Kwan JL, Lapointe-Shaw L, Rawal S, Tang T, Weinerman A, Cram P, Dhalla IA, Hwang SW, Laupacis A, Mamdani MM, Shadowitz S, Upshur R, Reid RJ, Razak F.

CMAJ Open. 2017 Dec 11;5(4):E842-E849. doi: 10.9778/cmajo.20170097. Epub 2017 Dec 13.

22.

Top 10 research priorities in head and neck cancer: Results of an Alberta priority setting partnership of patients, caregivers, family members, and clinicians.

Lechelt LA, Rieger JM, Cowan K, Debenham BJ, Krewski B, Nayar S, Regunathan A, Seikaly H, Singh AE, Laupacis A; Alberta Head and Neck Cancer Priority Setting Partnership Steering Committee.

Head Neck. 2018 Mar;40(3):544-554. doi: 10.1002/hed.24998. Epub 2017 Nov 17.

PMID:
29149525
23.

The kidney cancer research priority-setting partnership: Identifying the top 10 research priorities as defined by patients, caregivers, and expert clinicians.

Jones J, Bhatt J, Avery J, Laupacis A, Cowan K, Basappa N, Basiuk J, Canil C, Al-Asaaed S, Heng D, Wood L, Stacey D, Kollmannsberger C, Jewett MAS.

Can Urol Assoc J. 2017 Dec;11(12):379-387. doi: 10.5489/cuaj.4590. Epub 2017 Nov 1.

24.

Impact of the pan-Canadian Oncology Drug Review on provincial concordance with respect to cancer drug funding decisions and time to funding.

Srikanthan A, Mai H, Penner N, Amir E, Laupacis A, Sabharwal M, Chan KKW.

Curr Oncol. 2017 Oct;24(5):295-301. doi: 10.3747/co.24.3648. Epub 2017 Oct 25.

25.

Association Between Immigrant Status and End-of-Life Care in Ontario, Canada.

Yarnell CJ, Fu L, Manuel D, Tanuseputro P, Stukel T, Pinto R, Scales DC, Laupacis A, Fowler RA.

JAMA. 2017 Oct 17;318(15):1479-1488. doi: 10.1001/jama.2017.14418.

26.

Temporal Trends in Use of Composite End Points in Major Cardiovascular Randomized Clinical Trials in Prominent Medical Journals.

Tan NS, Ali SH, Lebovic G, Mamdani M, Laupacis A, Yan AT.

Circ Cardiovasc Qual Outcomes. 2017 Oct;10(10). pii: e003753. doi: 10.1161/CIRCOUTCOMES.117.003753. Review.

PMID:
28954803
27.

Hypertension management research priorities from patients, caregivers, and healthcare providers: A report from the Hypertension Canada Priority Setting Partnership Group.

Khan N, Bacon SL, Khan S, Perlmutter S, Gerlinsky C, Dermer M, Johnson L, Alves F, McLean D, Laupacis A, Pui M, Berg A, Flowitt F; Hypertension Canada Priority Setting Partnership Group.

J Clin Hypertens (Greenwich). 2017 Nov;19(11):1063-1069. doi: 10.1111/jch.13091. Epub 2017 Sep 25.

28.

Finding the right balance between precision medicine and personalized care.

McAlister FA, Laupacis A, Armstrong PW.

CMAJ. 2017 Aug 21;189(33):E1065-E1068. doi: 10.1503/cmaj.170107. Review. No abstract available.

29.

Effect of High-Dose vs Standard-Dose Wintertime Vitamin D Supplementation on Viral Upper Respiratory Tract Infections in Young Healthy Children.

Aglipay M, Birken CS, Parkin PC, Loeb MB, Thorpe K, Chen Y, Laupacis A, Mamdani M, Macarthur C, Hoch JS, Mazzulli T, Maguire JL; TARGet Kids! Collaboration.

JAMA. 2017 Jul 18;318(3):245-254. doi: 10.1001/jama.2017.8708.

30.

Patients' Perspectives on Outcomes of Care After Discharge From the Emergency Department: A Qualitative Study.

Vaillancourt S, Seaton MB, Schull MJ, Cheng AHY, Beaton DE, Laupacis A, Dainty KN.

Ann Emerg Med. 2017 Nov;70(5):648-658.e2. doi: 10.1016/j.annemergmed.2017.05.034. Epub 2017 Jul 14.

PMID:
28712607
31.

Protocol for a randomised controlled trial evaluating the effects of providing essential medicines at no charge: the Carefully seLected and Easily Accessible at No Charge Medicines (CLEAN Meds) trial.

Persaud N, Lee T, Ahmad H, Li W, Taglione MS, Rajakulasingam Y, Umali N, Boozary A, Glazier RH, Gomes T, Hwang SW, Jüni P, Law M, Mamdani MM, Manns B, Martin D, Morgan S, Oh P, Pinto AD, Shah BR, Sullivan FM, Thorpe KE, Tu K, Laupacis A.

BMJ Open. 2017 Jun 12;7(5):e015686. doi: 10.1136/bmjopen-2016-015686.

32.

Setting Research Priorities for Kidney Cancer.

Jones JM, Bhatt J, Avery J, Laupacis A, Cowan K, Basappa NS, Basiuk J, Canil C, Al-Asaaed S, Heng DYC, Wood L, Stacey D, Kollmannsberger C, Jewett MAS.

Eur Urol. 2017 Dec;72(6):861-864. doi: 10.1016/j.eururo.2017.04.011. Epub 2017 May 8.

PMID:
28495043
33.

Priority setting in paediatric preventive care research.

Lavigne M, Birken CS, Maguire JL, Straus S, Laupacis A.

Arch Dis Child. 2017 Aug;102(8):748-753. doi: 10.1136/archdischild-2016-312284. Epub 2017 Apr 12.

PMID:
28404552
34.

Development of a preliminary essential medicines list for Canada.

Taglione MS, Ahmad H, Slater M, Aliarzadeh B, Glazier RH, Laupacis A, Persaud N.

CMAJ Open. 2017 Feb 16;5(1):E137-E143. doi: 10.9778/cmajo.20160122. eCollection 2017 Jan-Mar.

35.

A qualitative study of emergency physicians' perspectives on PROMS in the emergency department.

Dainty KN, Seaton B, Laupacis A, Schull M, Vaillancourt S.

BMJ Qual Saf. 2017 Sep;26(9):714-721. doi: 10.1136/bmjqs-2016-006012. Epub 2017 Feb 9.

36.

Meta-analysis of timing of endovascular aneurysm treatment in subarachnoid haemorrhage: inconsistent results of early treatment within 1 day.

Rawal S, Alcaide-Leon P, Macdonald RL, Rinkel GJ, Victor JC, Krings T, Kapral MK, Laupacis A.

J Neurol Neurosurg Psychiatry. 2017 Mar;88(3):241-248. doi: 10.1136/jnnp-2016-314596. Epub 2017 Jan 18. Review.

PMID:
28100721
37.

Engaging Patients and Clinicians in Establishing Research Priorities for Gestational Diabetes Mellitus.

Rees SE, Chadha R, Donovan LE, Guitard AL, Koppula S, Laupacis A, Simpson S, Johnson JA.

Can J Diabetes. 2017 Apr;41(2):156-163. doi: 10.1016/j.jcjd.2016.08.219. Epub 2016 Nov 21.

PMID:
27881298
38.

A randomized controlled trial comparing in-person and wiki-inspired nominal group techniques for engaging stakeholders in chronic kidney disease research prioritization.

Elliott MJ, Straus SE, Pannu N, Ahmed SB, Laupacis A, Chong GC, Hillier DR, Huffman KT, Lei AC, Villanueva BV, Young DM, Tam-Tham H, Donald M, Lillie E, Manns BJ, Hemmelgarn BR.

BMC Med Inform Decis Mak. 2016 Aug 24;16:113. doi: 10.1186/s12911-016-0351-y.

39.

Potential Cost-Effectiveness of Ambulatory Cardiac Rhythm Monitoring After Cryptogenic Stroke.

Yong JH, Thavorn K, Hoch JS, Mamdani M, Thorpe KE, Dorian P, Sharma M, Laupacis A, Gladstone DJ; EMBRACE Steering Committee.

Stroke. 2016 Sep;47(9):2380-5. doi: 10.1161/STROKEAHA.115.011979. Epub 2016 Jul 28.

40.

SPIRIT 2013 Statement: defining standard protocol items for clinical trials.

Chan AW, Tetzlaff JM, Altman DG, Laupacis A, Gøtzsche PC, Krle A-Jerić K, Hrobjartsson A, Mann H, Dickersin K, Berlin JA, Dore CJ, Parulekar WR, Summerskill WS, Groves T, Schulz KF, Sox HC, Rockhold FW, Rennie D, Moher D.

Rev Panam Salud Publica. 2015 Dec;38(6):506-14.

41.

Predictors of diagnostic neuroimaging delays among adults presenting with symptoms suggestive of acute stroke in Ontario: a prospective cohort study.

Burton KR, Kapral MK, Li S, Fang J, Moody AR, Krahn M, Laupacis A.

CMAJ Open. 2016 Jun 20;4(2):E331-7. doi: 10.9778/cmajo.20150110. eCollection 2016 Apr-Jun.

42.

Efficacy and safety of non-immersive virtual reality exercising in stroke rehabilitation (EVREST): a randomised, multicentre, single-blind, controlled trial.

Saposnik G, Cohen LG, Mamdani M, Pooyania S, Ploughman M, Cheung D, Shaw J, Hall J, Nord P, Dukelow S, Nilanont Y, De Los Rios F, Olmos L, Levin M, Teasell R, Cohen A, Thorpe K, Laupacis A, Bayley M; Stroke Outcomes Research Canada.

Lancet Neurol. 2016 Sep;15(10):1019-27. doi: 10.1016/S1474-4422(16)30121-1. Epub 2016 Jun 27.

43.

Determining the research priorities for patients with chronic kidney disease not on dialysis.

Hemmelgarn BR, Pannu N, Ahmed SB, Elliott MJ, Tam-Tham H, Lillie E, Straus SE, Donald M, Barnieh L, Chong GC, Hillier DR, Huffman KT, Lei AC, Villanueva BV, Young DM, Fowler EA, Manns BJ, Laupacis A.

Nephrol Dial Transplant. 2017 May 1;32(5):847-854. doi: 10.1093/ndt/gfw065.

44.

The Influence of Socioeconomic Status on Selection of Anticoagulation for Atrial Fibrillation.

Sholzberg M, Gomes T, Juurlink DN, Yao Z, Mamdani MM, Laupacis A.

PLoS One. 2016 Feb 25;11(2):e0149142. doi: 10.1371/journal.pone.0149142. eCollection 2016.

45.

Survival Analysis in the Presence of Competing Risks: The Example of Waitlisted Kidney Transplant Candidates.

Sapir-Pichhadze R, Pintilie M, Tinckam KJ, Laupacis A, Logan AG, Beyene J, Kim SJ.

Am J Transplant. 2016 Jul;16(7):1958-66. doi: 10.1111/ajt.13717. Epub 2016 Mar 3. Review.

46.

Early Cholecystectomy for Acute Cholecystitis Offers the Best Outcomes at the Least Cost: A Model-Based Cost-Utility Analysis.

de Mestral C, Hoch JS, Laupacis A, Wijeysundera HC, Rotstein OD, Alali AS, Nathens AB.

J Am Coll Surg. 2016 Feb;222(2):185-94. doi: 10.1016/j.jamcollsurg.2015.10.015. Epub 2015 Nov 25.

PMID:
26705901
47.

Prevalence of Body Mass Index Lower Than 16 Among Women in Low- and Middle-Income Countries.

Razak F, Corsi DJ, Slutsky AS, Kurpad A, Berkman L, Laupacis A, Subramanian SV.

JAMA. 2015 Nov 24;314(20):2164-71. doi: 10.1001/jama.2015.15666. Erratum in: JAMA. 2016 Jan 12;315(2):204.

PMID:
26599184
48.

Validation of the 9-Point and 24-Point Hematoma Expansion Prediction Scores and Derivation of the PREDICT A/B Scores.

Huynh TJ, Aviv RI, Dowlatshahi D, Gladstone DJ, Laupacis A, Kiss A, Hill MD, Molina CA, Rodriguez-Luna D, Dzialowski I, Silva Y, Kobayashi A, Lum C, Boulanger JM, Gubitz G, Bhatia R, Padma V, Roy J, Kase CS, Symons SP, Demchuk AM; PREDICT/Sunnybrook CTA Investigators.

Stroke. 2015 Nov;46(11):3105-10. doi: 10.1161/STROKEAHA.115.009893. Epub 2015 Oct 13.

PMID:
26463691
49.

Assessing the extent to which current clinical research is consistent with patient priorities: a scoping review using a case study in patients on or nearing dialysis.

Jun M, Manns B, Laupacis A, Manns L, Rehal B, Crowe S, Hemmelgarn BR.

Can J Kidney Health Dis. 2015 Oct 1;2:35. doi: 10.1186/s40697-015-0070-9. eCollection 2015.

50.

Immune Sensitization and Mortality in Wait-Listed Kidney Transplant Candidates.

Sapir-Pichhadze R, Tinckam KJ, Laupacis A, Logan AG, Beyene J, Kim SJ.

J Am Soc Nephrol. 2016 Feb;27(2):570-8. doi: 10.1681/ASN.2014090894. Epub 2015 Jun 8.

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