Sort by
Items per page

Send to

Choose Destination

Search results

Items: 48


Mechanistic insights into store-operated Ca2+ entry during excitation-contraction coupling in skeletal muscle.

Koenig X, Choi RH, Schicker K, Singh DP, Hilber K, Launikonis BS.

Biochim Biophys Acta Mol Cell Res. 2019 Feb 27. pii: S0167-4889(19)30022-9. doi: 10.1016/j.bbamcr.2019.02.014. [Epub ahead of print]


Store-operated Ca2+ entry is activated by every action potential in skeletal muscle.

Koenig X, Choi RH, Launikonis BS.

Commun Biol. 2018 Apr 19;1:31. doi: 10.1038/s42003-018-0033-7. eCollection 2018.


Junctional membrane Ca2+ dynamics in human muscle fibers are altered by malignant hyperthermia causative RyR mutation.

Cully TR, Choi RH, Bjorksten AR, Stephenson DG, Murphy RM, Launikonis BS.

Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8215-8220. doi: 10.1073/pnas.1800490115. Epub 2018 Jul 23.


NHE- and diffusion-dependent proton fluxes across the tubular system membranes of fast-twitch muscle fibers of the rat.

Launikonis BS, Cully TR, Csernoch L, Stephenson DG.

J Gen Physiol. 2018 Jan 2;150(1):95-110. doi: 10.1085/jgp.201711891. Epub 2017 Dec 11.


Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest.

Mills RJ, Titmarsh DM, Koenig X, Parker BL, Ryall JG, Quaife-Ryan GA, Voges HK, Hodson MP, Ferguson C, Drowley L, Plowright AT, Needham EJ, Wang QD, Gregorevic P, Xin M, Thomas WG, Parton RG, Nielsen LK, Launikonis BS, James DE, Elliott DA, Porrello ER, Hudson JE.

Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):E8372-E8381. doi: 10.1073/pnas.1707316114. Epub 2017 Sep 15.


Dantrolene requires Mg2+ to arrest malignant hyperthermia.

Choi RH, Koenig X, Launikonis BS.

Proc Natl Acad Sci U S A. 2017 May 2;114(18):4811-4815. doi: 10.1073/pnas.1619835114. Epub 2017 Apr 3.


Doublet stimulation increases Ca2+ binding to troponin C to ensure rapid force development in skeletal muscle.

Bakker AJ, Cully TR, Wingate CD, Barclay CJ, Launikonis BS.

J Gen Physiol. 2017 Mar 6;149(3):323-334. doi: 10.1085/jgp.201611727. Epub 2017 Feb 16.


Human skeletal muscle plasmalemma alters its structure to change its Ca2+-handling following heavy-load resistance exercise.

Cully TR, Murphy RM, Roberts L, Raastad T, Fassett RG, Coombes JS, Jayasinghe ID, Launikonis BS.

Nat Commun. 2017 Feb 13;8:14266. doi: 10.1038/ncomms14266.


Additional in-series compliance reduces muscle force summation and alters the time course of force relaxation during fixed-end contractions.

Mayfield DL, Launikonis BS, Cresswell AG, Lichtwark GA.

J Exp Biol. 2016 Nov 15;219(Pt 22):3587-3596. Epub 2016 Sep 8.


Leaky ryanodine receptors delay the activation of store overload-induced Ca2+ release, a mechanism underlying malignant hyperthermia-like events in dystrophic muscle.

Cully TR, Launikonis BS.

Am J Physiol Cell Physiol. 2016 Apr 15;310(8):C673-80. doi: 10.1152/ajpcell.00366.2015. Epub 2016 Jan 28.


A quantitative description of tubular system Ca(2+) handling in fast- and slow-twitch muscle fibres.

Cully TR, Edwards JN, Murphy RM, Launikonis BS.

J Physiol. 2016 Jun 1;594(11):2795-810. doi: 10.1113/JP271658. Epub 2016 Feb 29.


Observation of the molecular organization of calcium release sites in fast- and slow-twitch skeletal muscle with nanoscale imaging.

Jayasinghe ID, Munro M, Baddeley D, Launikonis BS, Soeller C.

J R Soc Interface. 2014 Oct 6;11(99). pii: 20140570. doi: 10.1098/rsif.2014.0570.


Activation and propagation of Ca2+ release from inside the sarcoplasmic reticulum network of mammalian skeletal muscle.

Cully TR, Edwards JN, Launikonis BS.

J Physiol. 2014 Sep 1;592(17):3727-46. doi: 10.1113/jphysiol.2014.274274. Epub 2014 Jun 27.


Evidence that collaboration between HIF-1α and Notch-1 promotes neuronal cell death in ischemic stroke.

Cheng YL, Park JS, Manzanero S, Choi Y, Baik SH, Okun E, Gelderblom M, Fann DY, Magnus T, Launikonis BS, Mattson MP, Sobey CG, Jo DG, Arumugam TV.

Neurobiol Dis. 2014 Feb;62:286-95. doi: 10.1016/j.nbd.2013.10.009. Epub 2013 Oct 16.


Three-dimensional reconstruction and analysis of the tubular system of vertebrate skeletal muscle.

Jayasinghe ID, Launikonis BS.

J Cell Sci. 2013 Sep 1;126(Pt 17):4048-58. doi: 10.1242/jcs.131565. Epub 2013 Jun 26.


Examination of the subsarcolemmal tubular system of mammalian skeletal muscle fibers.

Jayasinghe ID, Lo HP, Morgan GP, Baddeley D, Parton RG, Soeller C, Launikonis BS.

Biophys J. 2013 Jun 4;104(11):L19-21. doi: 10.1016/j.bpj.2013.04.029.


Store-operated Ca²⁺ entry is not required for store refilling in skeletal muscle.

Cully TR, Launikonis BS.

Clin Exp Pharmacol Physiol. 2013 May;40(5):338-44. doi: 10.1111/1440-1681.12078. Review.


Evidence that the EphA2 receptor exacerbates ischemic brain injury.

Thundyil J, Manzanero S, Pavlovski D, Cully TR, Lok KZ, Widiapradja A, Chunduri P, Jo DG, Naruse C, Asano M, Launikonis BS, Sobey CG, Coulthard MG, Arumugam TV.

PLoS One. 2013;8(1):e53528. doi: 10.1371/journal.pone.0053528. Epub 2013 Jan 7.


Growth hormone secretagogues preserve the electrophysiological properties of mouse cardiomyocytes isolated from in vitro ischemia/reperfusion heart.

Ma Y, Zhang L, Launikonis BS, Chen C.

Endocrinology. 2012 Nov;153(11):5480-90. doi: 10.1210/en.2012-1404. Epub 2012 Sep 4.


Changes in plasma membrane Ca-ATPase and stromal interacting molecule 1 expression levels for Ca(2+) signaling in dystrophic mdx mouse muscle.

Cully TR, Edwards JN, Friedrich O, Stephenson DG, Murphy RM, Launikonis BS.

Am J Physiol Cell Physiol. 2012 Sep 1;303(5):C567-76. doi: 10.1152/ajpcell.00144.2012. Epub 2012 Jul 11.


Growth hormone secretagogues protect mouse cardiomyocytes from in vitro ischemia/reperfusion injury through regulation of intracellular calcium.

Ma Y, Zhang L, Edwards JN, Launikonis BS, Chen C.

PLoS One. 2012;7(4):e35265. doi: 10.1371/journal.pone.0035265. Epub 2012 Apr 6.


Longitudinal and transversal propagation of excitation along the tubular system of rat fast-twitch muscle fibres studied by high speed confocal microscopy.

Edwards JN, Cully TR, Shannon TR, Stephenson DG, Launikonis BS.

J Physiol. 2012 Feb 1;590(3):475-92. doi: 10.1113/jphysiol.2011.221796. Epub 2011 Dec 12.


Store-operated calcium entry remains fully functional in aged mouse skeletal muscle despite a decline in STIM1 protein expression.

Edwards JN, Blackmore DG, Gilbert DF, Murphy RM, Launikonis BS.

Aging Cell. 2011 Aug;10(4):675-85. doi: 10.1111/j.1474-9726.2011.00706.x. Epub 2011 May 3.


Toward the roles of store-operated Ca2+ entry in skeletal muscle.

Launikonis BS, Murphy RM, Edwards JN.

Pflugers Arch. 2010 Oct;460(5):813-23. doi: 10.1007/s00424-010-0856-7. Epub 2010 Jun 25. Review.


Ultra-rapid activation and deactivation of store-operated Ca(2+) entry in skeletal muscle.

Edwards JN, Murphy RM, Cully TR, von Wegner F, Friedrich O, Launikonis BS.

Cell Calcium. 2010 May;47(5):458-67. doi: 10.1016/j.ceca.2010.04.001.


Upregulation of store-operated Ca2+ entry in dystrophic mdx mouse muscle.

Edwards JN, Friedrich O, Cully TR, von Wegner F, Murphy RM, Launikonis BS.

Am J Physiol Cell Physiol. 2010 Jul;299(1):C42-50. doi: 10.1152/ajpcell.00524.2009. Epub 2010 Apr 28.


Rapid Ca2+ flux through the transverse tubular membrane, activated by individual action potentials in mammalian skeletal muscle.

Launikonis BS, Stephenson DG, Friedrich O.

J Physiol. 2009 May 15;587(Pt 10):2299-312. doi: 10.1113/jphysiol.2009.168682. Epub 2009 Mar 30.


Inhibitory control over Ca(2+) sparks via mechanosensitive channels is disrupted in dystrophin deficient muscle but restored by mini-dystrophin expression.

Teichmann MD, Wegner FV, Fink RH, Chamberlain JS, Launikonis BS, Martinac B, Friedrich O.

PLoS One. 2008;3(11):e3644. doi: 10.1371/journal.pone.0003644. Epub 2008 Nov 4.


The accessibility and interconnectivity of the tubular system network in toad skeletal muscle.

Edwards JN, Launikonis BS.

J Physiol. 2008 Nov 1;586(21):5077-89. doi: 10.1113/jphysiol.2008.155127. Epub 2008 Sep 4.


Calcium-dependent inactivation terminates calcium release in skeletal muscle of amphibians.

Ríos E, Zhou J, Brum G, Launikonis BS, Stern MD.

J Gen Physiol. 2008 Apr;131(4):335-48. doi: 10.1085/jgp.200709870. Epub 2008 Mar 17.


Dynamic regulation of the large exocytotic fusion pore in pancreatic acinar cells.

Larina O, Bhat P, Pickett JA, Launikonis BS, Shah A, Kruger WA, Edwardson JM, Thorn P.

Mol Biol Cell. 2007 Sep;18(9):3502-11. Epub 2007 Jun 27.


Store-operated Ca2+ entry during intracellular Ca2+ release in mammalian skeletal muscle.

Launikonis BS, Ríos E.

J Physiol. 2007 Aug 15;583(Pt 1):81-97. Epub 2007 Jun 14.


The elusive role of store depletion in the control of intracellular calcium release.

Ríos E, Launikonis BS, Royer L, Brum G, Zhou J.

J Muscle Res Cell Motil. 2006;27(5-7):337-50. Epub 2006 Aug 25. Review.


The changes in Ca2+ sparks associated with measured modifications of intra-store Ca2+ concentration in skeletal muscle.

Launikonis BS, Zhou J, Santiago D, Brum G, Ríos E.

J Gen Physiol. 2006 Jul;128(1):45-54. Epub 2006 Jun 12.


Depletion "skraps" and dynamic buffering inside the cellular calcium store.

Launikonis BS, Zhou J, Royer L, Shannon TR, Brum G, Ríos E.

Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2982-7. Epub 2006 Feb 10.


Concerted vs. sequential. Two activation patterns of vast arrays of intracellular Ca2+ channels in muscle.

Zhou J, Brum G, González A, Launikonis BS, Stern MD, Ríos E.

J Gen Physiol. 2005 Oct;126(4):301-9.


A probable role of dihydropyridine receptors in repression of Ca2+ sparks demonstrated in cultured mammalian muscle.

Zhou J, Yi J, Royer L, Launikonis BS, González A, García J, Ríos E.

Am J Physiol Cell Physiol. 2006 Feb;290(2):C539-53. Epub 2005 Sep 7. Erratum in: Am J Physiol Cell Physiol. 2006 May;290(5):C1459.


Confocal imaging of [Ca2+] in cellular organelles by SEER, shifted excitation and emission ratioing of fluorescence.

Launikonis BS, Zhou J, Royer L, Shannon TR, Brum G, Ríos E.

J Physiol. 2005 Sep 1;567(Pt 2):523-43. Epub 2005 Jun 9.


Osmotic properties of the sealed tubular system of toad and rat skeletal muscle.

Launikonis BS, Stephenson DG.

J Gen Physiol. 2004 Mar;123(3):231-47.


Ca2+ sparks and embers of mammalian muscle. Properties of the sources.

Zhou J, Brum G, Gonzalez A, Launikonis BS, Stern MD, Rios E.

J Gen Physiol. 2003 Jul;122(1):95-114.


Identification of the coupling between skeletal muscle store-operated Ca2+ entry and the inositol trisphosphate receptor.

Launikonis BS, Barnes M, Stephenson DG.

Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2941-4. Epub 2003 Feb 24.


Properties of the vertebrate skeletal muscle tubular system as a sealed compartment.

Launikonis BS, Stephenson DG.

Cell Biol Int. 2002;26(10):921-9.


Supplemental Content

Loading ...
Support Center